{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T22:15:14Z","timestamp":1780352114016,"version":"3.54.1"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T00:00:00Z","timestamp":1430438400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Radiol"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1007\/s00330-015-3782-4","type":"journal-article","created":{"date-parts":[[2015,4,30]],"date-time":"2015-04-30T11:51:08Z","timestamp":1430394668000},"page":"3577-3585","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Changes in structural lung disease in cystic fibrosis children over 4\u00a0years as evaluated by high-resolution computed tomography"],"prefix":"10.1007","volume":"25","author":[{"given":"Carlos","family":"Carpio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo","family":"Albi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Carlos","family":"Ray\u00f3n-Aledo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodolfo","family":"\u00c1lvarez-Sala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa","family":"Gir\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Concepci\u00f3n","family":"Prados","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paloma","family":"Caballero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,5,1]]},"reference":[{"key":"3782_CR1","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/S0140-6736(03)12567-6","volume":"361","author":"F Ratjen","year":"2003","unstructured":"Ratjen F, Goring G (2003) Cystic fibrosis. Lancet 361:681\u2013689","journal-title":"Lancet"},{"key":"3782_CR2","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1093\/oxfordjournals.aje.a008664","volume":"143","author":"M Corey","year":"1996","unstructured":"Corey M, Farewell W (1996) Determinants of mortality from cystic fibrosis in Canada, 1970\u20131989. Am J Epidemiol 143:1007\u20131017","journal-title":"Am J Epidemiol"},{"key":"3782_CR3","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1002\/ppul.1113","volume":"32","author":"M Gappa","year":"2001","unstructured":"Gappa M, Ranganathan SC, Stocks J (2001) Lung function testing in infants with cystic fibrosis: lessons from the past and future directions. Pediatr Pulmonol 32:228\u2013381","journal-title":"Pediatr Pulmonol"},{"key":"3782_CR4","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/S0720-048X(00)00236-9","volume":"37","author":"FB Demirkazik","year":"2001","unstructured":"Demirkazik FB, Ariy\u00fcrek OM, Oz\u00e7elik U, G\u00f6\u00e7men A, Hassanabad HK, Kiper N (2001) High resolution CT in children with cystic fibrosis: correlation with pulmonary functions and radiograph scores. Eur J Radiol 37:54\u201359","journal-title":"Eur J Radiol"},{"key":"3782_CR5","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1067\/mpd.2001.111820","volume":"138","author":"TE Robinson","year":"2001","unstructured":"Robinson TE, Leung AN, Northway WH, Blankenberg FG, Bloch DA, Oehlert JW et al (2001) Spirometer-triggered high-resolution computed tomography and pulmonary function measurements during and acute exacerbation in patients with cystic fibrosis. J Pediatr 138:553\u2013559","journal-title":"J Pediatr"},{"key":"3782_CR6","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.jpeds.2004.02.038","volume":"145","author":"AS Brody","year":"2004","unstructured":"Brody AS, Klein JS, Molina PL, Quan J, Bean JA, Wilmott RW (2004) High-resolution computed tomography in young patients with cystic fibrosis: distribution of abnormalitites and correlation with pulmonary function tests. J Pediatr 145:32\u201338","journal-title":"J Pediatr"},{"key":"3782_CR7","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1007\/s00330-007-0810-z","volume":"18","author":"A Oikonomou","year":"2008","unstructured":"Oikonomou A, Tsanakas J, Hatziagorou E, Kirvassilis F, Efremidis S, Prassopoulos P (2008) High resolution computed tomography of the chest in cystic fibrosis (CF): is simplification of scoring systems feasible? Eur Radiol 18:538\u2013547","journal-title":"Eur Radiol"},{"key":"3782_CR8","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1007\/s00330-002-1340-3","volume":"12","author":"A Oikonomou","year":"2002","unstructured":"Oikonomou A, Manavis J, Karaguanni P, Tsanakas J, Wells AU, Hansell DM et al (2002) Loss of FEV1 in cystic fibrosis: correlation with HRCT features. Eur Radiol 12:2229\u20132235","journal-title":"Eur Radiol"},{"key":"3782_CR9","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1183\/09031936.03.00006603","volume":"23","author":"PA Jong de","year":"2004","unstructured":"de Jong PA, Nakano Y, Lequin MH, Mayo JR, Woods R, Par\u00e9 PD et al (2004) Progressive damage on high resolution computed tomography despite stable lung function in cystic fibrosis. Eur Respir J 23:93\u201397","journal-title":"Eur Respir J"},{"key":"3782_CR10","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.2214\/AJR.07.3000","volume":"190","author":"F Cademartiri","year":"2008","unstructured":"Cademartiri F, Luccichenti G, Palumbo AA, Maffei E, Pisi G, Zompatori M et al (2008) Predictive value of chest CT in patients with cystic fibrosis: a single-center 10-year experience. AJR Am J Roentgenol 190:1475\u20131580","journal-title":"AJR Am J Roentgenol"},{"key":"3782_CR11","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1136\/thoraxjnl-2011-200912","volume":"67","author":"LS Mott","year":"2012","unstructured":"Mott LS, Park J, Murray CP, Gangell CL, de Klerk NH, Robinson PJ et al (2012) Progression of early structural lung disease in young children with cystic fibrosis assessed using CT. Thorax 67:509\u2013516","journal-title":"Thorax"},{"key":"3782_CR12","first-page":"567","volume":"19","author":"P Casan","year":"1983","unstructured":"Casan P, Roca J, Sanchis J (1983) Spirometric response to a bronchodilator. Reference values for healthy children and adolescents. Bull Eur Physiopathol Respir 19:567\u2013569","journal-title":"Bull Eur Physiopathol Respir"},{"key":"3782_CR13","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1183\/09031936.05.00034805","volume":"26","author":"MR Miller","year":"2005","unstructured":"Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A et al (2005) Standardisation of spirometry. Eur Respir J 26:319\u2013338","journal-title":"Eur Respir J"},{"key":"3782_CR14","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1542\/peds.63.1.24","volume":"63","author":"D Brasfield","year":"1979","unstructured":"Brasfield D, Hicks G, Soong S, Tiller RE (1979) The chest roentgenogram in cystic fibrosis: a new scoring system. Pediatrics 63:24\u201329","journal-title":"Pediatrics"},{"key":"3782_CR15","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.2214\/ajr.134.6.1195","volume":"134","author":"D Brasfield","year":"1980","unstructured":"Brasfield D, Hicks G, Soong S, Tiller R (1980) Evaluation of scoring system of the chest radiograph in cystic fibrosis: a collaborative study. AJR Am J Roentgenol 134:1195\u20131198","journal-title":"AJR Am J Roentgenol"},{"key":"3782_CR16","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1148\/radiology.179.3.2027992","volume":"179","author":"M Bhalla","year":"1991","unstructured":"Bhalla M, Turcios N, Aponte V, Jenkins M, Leitman BS, McCauley DI et al (1991) Cystic fibrosis: scoring system with thin-section CT. Radiology 179:783\u2013788","journal-title":"Radiology"},{"key":"3782_CR17","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.rx.2011.04.007","volume":"54","author":"G Albi","year":"2012","unstructured":"Albi G, Ray\u00f3n-Aldeo JC, Caballero P, Rosado P, Garc\u00eda-Esparza E (2012) Fibrosis qu\u00edstica en im\u00e1genes. Clasificaci\u00f3n de Bhalla para la tomograf\u00eda computarizada en pacientes pedi\u00e1tricos. Radiolog\u00eda 54:260\u2013268","journal-title":"Radiolog\u00eda"},{"key":"3782_CR18","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1136\/thx.2005.045146","volume":"61","author":"PA Jong de","year":"2006","unstructured":"de Jong PA, Lindblad A, Rubin L, Hop WC, de Jongste JC, Brink M et al (2006) Progression of lung disease on computed tomography and pulmonary function tests in children and adults with cystic fibrosis. Thorax 61:80\u201385","journal-title":"Thorax"},{"key":"3782_CR19","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1378\/chest.130.5.1424","volume":"130","author":"EP Judge","year":"2006","unstructured":"Judge EP, Dodd JD, Masterson JB, Gallagher CG (2006) Pulmonary abnormalities on high-resolution CT demonstrate more rapid decline than FEV1 in adults with cystic fibrosis. Chest 130:1424\u20131432","journal-title":"Chest"},{"key":"3782_CR20","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/S0022-3476(97)70025-8","volume":"131","author":"M Corey","year":"1997","unstructured":"Corey M, Edwards L, Levison H, Knowles M (1997) Longitudinal analysis of pulmonary function decline in patients with cystic fibrosis. J Pediatr 131:809\u201314","journal-title":"J Pediatr"},{"key":"3782_CR21","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1378\/chest.123.5.1655","volume":"123","author":"ML Goris","year":"2003","unstructured":"Goris ML, Zhu HJ, Blankeberg F, Chan F, Robinson TE (2003) An automated approach to quantitative air trapping measurements in mild cystic fibrosis. Chest 123:1655\u20131663","journal-title":"Chest"},{"key":"3782_CR22","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1093\/oxfordjournals.aje.a009172","volume":"145","author":"M Rosenfeld","year":"1997","unstructured":"Rosenfeld M, Davis R, Fitz Simmons S, Pepe M, Ramsey B (1997) Gender gap in cystic fibrosis mortality. Am J Epidemiol 145:794\u2013803","journal-title":"Am J Epidemiol"},{"key":"3782_CR23","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1002\/ppul.21265","volume":"45","author":"HV Olesen","year":"2010","unstructured":"Olesen HV, Pressler T, Hjelte L, Mared L, Lindblad A, Knudsen PK et al (2010) Gender differences in the Scandinavian cystic fibrosis population. Pediatr Pulmonol 45:959\u2013965","journal-title":"Pediatr Pulmonol"},{"key":"3782_CR24","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1136\/thorax.57.2.142","volume":"57","author":"MJ Ledson","year":"2002","unstructured":"Ledson MJ, Gallagher MJ, Jackson M, Hart CA, Walshaw MJ (2002) Outcome of Burkholderia cepacia colonization in an adult cystic fibrosis centre. Thorax 57:142\u2013145","journal-title":"Thorax"},{"key":"3782_CR25","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.jpeds.2009.05.005","volume":"155","author":"SM Stick","year":"2009","unstructured":"Stick SM, Brennan S, Murray C, Douglas T, von Ungern-Sternberg BS, Garratt LW et al (2009) Bronchiectasis in infants and preschool children diagnosed with cystic fibrosis after newborn screening. J Pediatr 155:623\u2013628","journal-title":"J Pediatr"},{"key":"3782_CR26","doi-asserted-by":"crossref","first-page":"2824","DOI":"10.1378\/chest.128.4.2824","volume":"128","author":"N Verma","year":"2005","unstructured":"Verma N, Bush A, Buchdahl R (2005) Is there still a gender gap in cystic fibrosis? Chest 128:2824\u20132834","journal-title":"Chest"},{"key":"3782_CR27","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1056\/NEJMoa1301725","volume":"368","author":"PD Sly","year":"2013","unstructured":"Sly PD, Gangell CL, Chen L, Ware RS, Ranganathan S, Mott LS et al (2013) Risk factors for bronchiectasis in children with cystic fibrosis. N Engl J Med 368:1963\u20131970","journal-title":"N Engl J Med"},{"key":"3782_CR28","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1378\/chest.10-1763","volume":"139","author":"N Kapur","year":"2011","unstructured":"Kapur N, Masel JP, Watson D, Masters IB, Chang AB (2011) Bronchoarterial ratio on high-resolution CT scan of the chest in children without pulmonary pathology: need to redefine bronchial dilation. Chest 139:1445\u20131450","journal-title":"Chest"},{"key":"3782_CR29","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1164\/rccm.201111-2065OC","volume":"185","author":"M Loeve","year":"2012","unstructured":"Loeve M, Hop WC, de Bruijne M, van Hal PT, Robinson P, Aitken ML et al (2012) Chest computed tomography scores are predictive of survival in patients with cystic fibrosis awaiting lung transplantation. Am J Respir Crit Care Med 185:1096\u20131103","journal-title":"Am J Respir Crit Care Med"},{"key":"3782_CR30","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1148\/radiol.2312021393","volume":"231","author":"PA Jong De","year":"2004","unstructured":"De Jong PA, Ottink MD, Robben SG, Lequin MH, Hop WC, Hendriks JJ et al (2004) Pulmonary disease assessment in cystic fibrosis: comparison of CT-scoring systems and value of bronchial and arterial dimension measurements. Radiology 231:434\u2013439","journal-title":"Radiology"},{"key":"3782_CR31","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1148\/radiol.2422060030","volume":"242","author":"M Montaudon","year":"2007","unstructured":"Montaudon M, Berger P, Cangini-Sacher A, de Dietrich G, Tunon-de-Lara JM, Marthan et al (2007) Bronchial measurement with three-dimensional quantitative thin-section CT in patients with cystic fibrosis. Radiology 242:573\u2013581","journal-title":"Radiology"},{"key":"3782_CR32","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1164\/rccm.200901-0069OC","volume":"180","author":"PD Sly","year":"2009","unstructured":"Sly PD, Brennan S, Gangell C, de Klerk N, Murray C, Mott L et al (2009) Lung disease at diagnosis in infants with cystic fibrosis detected by newborn screening. Am J Respir Crit Care Med 180:146\u2013152","journal-title":"Am J Respir Crit Care Med"},{"key":"3782_CR33","unstructured":"Albi G. La tomograf\u00eda computarizada de alta resoluci\u00f3n en pacientes pedi\u00e1tricos con fibrosis qu\u00edstica: correlaci\u00f3n con la radiograf\u00eda del t\u00f3rax, la espirometr\u00eda y los datos cl\u00ednicos. Estudio dosim\u00e9trico [dissertation]. [Madrid (Spain)]: Aut\u00f3noma de Madrid University; 2009. 140 p. https:\/\/repositorio.uam.es\/xmlui\/bitstream\/handle\/10486\/4324\/29122_albi_rodriguez_gustavo.pdf?sequence=1 . Accessed 1 Oct 2014"},{"key":"3782_CR34","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1183\/09031936.00.15121700","volume":"15","author":"J Blic De","year":"2000","unstructured":"De Blic J, Midulla F, Barbato A, Clement A, Dab I, Eber E et al (2000) Bronchoalveolar lavage in children. ERS Task Force on bronchoalveolar lavage in children. European Respiratory Society. Eur Respir J 15:217\u201323","journal-title":"Eur Respir J"}],"container-title":["European Radiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-015-3782-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00330-015-3782-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-015-3782-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,6]],"date-time":"2022-05-06T19:04:49Z","timestamp":1651863889000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00330-015-3782-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5,1]]},"references-count":34,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["3782"],"URL":"https:\/\/doi.org\/10.1007\/s00330-015-3782-4","relation":{},"ISSN":["0938-7994","1432-1084"],"issn-type":[{"value":"0938-7994","type":"print"},{"value":"1432-1084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5,1]]}}}