{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:45:51Z","timestamp":1790696751712,"version":"4.1.0"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2015,10,30]],"date-time":"2015-10-30T00:00:00Z","timestamp":1446163200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Radiol"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1007\/s00330-015-4063-y","type":"journal-article","created":{"date-parts":[[2015,10,29]],"date-time":"2015-10-29T23:08:58Z","timestamp":1446160138000},"page":"2494-2501","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["MDCT Linear and Volumetric Analysis of Adrenal Glands: Normative Data and Multiparametric Assessment"],"prefix":"10.1007","volume":"26","author":[{"given":"Aline","family":"Carsin-Vu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Oubaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9bastien","family":"Mul\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna\u00eblle","family":"Janvier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Delemer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Soyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Hoeffel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,10,30]]},"reference":[{"key":"4063_CR1","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1148\/rg.295095026","volume":"29","author":"PT Johnson","year":"2009","unstructured":"Johnson PT, Horton KM, Fishman EK (2009) Adrenal imaging with multidetector CT: evidence-based protocol optimization and interpretative practice. Radiographics 29:1319\u20131331","journal-title":"Radiographics"},{"key":"4063_CR2","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1007\/s00330-013-3050-4","volume":"24","author":"J Schek","year":"2013","unstructured":"Schek J, Macht S, Klasen-Sansone J et al (2013) Clinical impact of hyperattenuation of adrenal glands on contrast-enhanced computed tomography of polytraumatised patients. Eur Radiol 24:527\u2013530","journal-title":"Eur Radiol"},{"key":"4063_CR3","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1007\/s00330-014-3192-z","volume":"24","author":"A Helck","year":"2014","unstructured":"Helck A, Hummel N, Meinel FG, Johnson T, Nikolaou K, Graser A (2014) Can single-phase dual-energy CT reliably identify adrenal adenomas? Eur Radiol 24:1636\u20131642","journal-title":"Eur Radiol"},{"key":"4063_CR4","doi-asserted-by":"crossref","first-page":"997","DOI":"10.2214\/ajr.172.4.10587135","volume":"172","author":"SA Sohaib","year":"1999","unstructured":"Sohaib SA, Hanson JA, Newell-Price JD et al (1999) CT appearance of the adrenal glands in adrenocorticotrophic hormone-dependent Cushing\u2019s syndrome. Am J Roentgenol 172:997\u20131002","journal-title":"Am J Roentgenol"},{"key":"4063_CR5","doi-asserted-by":"crossref","first-page":"843","DOI":"10.2214\/ajr.181.3.1810843","volume":"181","author":"RK Lingam","year":"2003","unstructured":"Lingam RK, Sohaib SA, Vlahos I et al (2003) CT of primary hyperaldosteronism (Conn\u2019s syndrome): the value of measuring the adrenal gland. Am J Roentgenol 181:843\u2013849","journal-title":"Am J Roentgenol"},{"key":"4063_CR6","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1507\/endocrj.43.573","volume":"43","author":"I G\u00fclmez","year":"1996","unstructured":"G\u00fclmez I, Kele\u015ftimur F, Durak AC, Ozesmi M (1996) Changes in the size of adrenal glands in acute pulmonary tuberculosis with therapy. Endocr J 43:573\u2013576","journal-title":"Endocr J"},{"key":"4063_CR7","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1507\/endocrj.52.183","volume":"52","author":"O Yildiz","year":"2005","unstructured":"Yildiz O, Gokce C, Alp E et al (2005) Investigation of the hypothalamo-pituitary-adrenal axis and changes in the size of adrenal glands in acute brucellosis. Endocr J 52:183\u2013188","journal-title":"Endocr J"},{"key":"4063_CR8","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s10654-011-9585-2","volume":"26","author":"SH Golden","year":"2011","unstructured":"Golden SH, Wand GS, Malhotra S, Kamel I, Horton K (2011) Reliability of hypothalamic\u2013pituitary\u2013adrenal axis assessment methods for use in population-based studies. Eur J Epidemiol 26:511\u2013525","journal-title":"Eur J Epidemiol"},{"key":"4063_CR9","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0165-1781(87)90022-9","volume":"21","author":"JD Amsterdam","year":"1987","unstructured":"Amsterdam JD, Marinelli DL, Arger P, Winokur A (1987) Assessment of adrenal gland volume by computed tomography in depressed patients and healthy volunteers: a pilot study. Psychiatry Res 21:189\u2013197","journal-title":"Psychiatry Res"},{"key":"4063_CR10","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.psyneuen.2010.05.007","volume":"36","author":"LV Kessing","year":"2011","unstructured":"Kessing LV, Willer IS, Knorr U (2011) Volume of the adrenal and pituitary glands in depression. Psychoneuroendocrinology 36:19\u201327","journal-title":"Psychoneuroendocrinology"},{"key":"4063_CR11","doi-asserted-by":"crossref","first-page":"229","DOI":"10.2190\/PM.38.3.a","volume":"38","author":"B Ludescher","year":"2008","unstructured":"Ludescher B, Najib A, Baar S et al (2008) Increase of visceral fat and adrenal gland volume in women with depression: preliminary results of a morphometric MRI study. Int J Psychiatry Med 38:229\u2013240","journal-title":"Int J Psychiatry Med"},{"key":"4063_CR12","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1097\/PSY.0b013e3181904f59","volume":"71","author":"B Ludescher","year":"2009","unstructured":"Ludescher B, Leitlein G, Schaefer J-E et al (2009) Changes of body composition in bulimia nervosa: increased visceral fat and adrenal gland size. Psychosom Med 71:93\u201397","journal-title":"Psychosom Med"},{"key":"4063_CR13","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.1038\/sj.bjc.6690603","volume":"80","author":"PJ Jenkins","year":"1999","unstructured":"Jenkins PJ, Sohaib SA, Trainer PJ, Lister TA, Besser GM, Reznek R (1999) Adrenal enlargement and failure of suppression of circulating cortisol by dexamethasone in patients with malignancy. Br J Cancer 80:1815\u20131819","journal-title":"Br J Cancer"},{"key":"4063_CR14","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1148\/radiol.2352031708","volume":"235","author":"N Benitah","year":"2005","unstructured":"Benitah N, Yeh BM, Qayyum A, Williams G, Breiman RS, Coakley FV (2005) Minor morphologic abnormalities of adrenal glands at CT: prognostic importance in patients with lung cancer. Radiology 235:517\u2013522","journal-title":"Radiology"},{"key":"4063_CR15","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.1007\/s00330-010-1804-9","volume":"20","author":"S Nougaret","year":"2010","unstructured":"Nougaret S, Jung B, Aufort S, Chanques G, Jaber S, Gallix B (2010) Adrenal gland volume measurement in septic shock and control patients: a pilot study. Eur Radiol 20:2348\u20132357","journal-title":"Eur Radiol"},{"key":"4063_CR16","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1097\/ALN.0b013e318225cfd7","volume":"115","author":"B Jung","year":"2011","unstructured":"Jung B, Nougaret S, Chanques G et al (2011) The absence of adrenal gland enlargement during septic shock predicts mortality: a computed tomography study of 239 patients. Anesthesiology 115:334\u2013343","journal-title":"Anesthesiology"},{"key":"4063_CR17","doi-asserted-by":"crossref","first-page":"e37","DOI":"10.1016\/j.crad.2013.08.017","volume":"69","author":"YZ Tang","year":"2014","unstructured":"Tang YZ, Bharwani N, Micco M, Akker S, Rockall AG, Sahdev A (2014) The prevalence of incidentally detected adrenal enlargement on CT. Clin Radiol 69:e37\u2013e42","journal-title":"Clin Radiol"},{"key":"4063_CR18","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1016\/j.acra.2014.06.008","volume":"21","author":"J Schneller","year":"2014","unstructured":"Schneller J, Reiser M, Beuschlein F et al (2014) Linear and volumetric evaluation of the adrenal gland\u2014MDCT-based measurements of the adrenals. Acad Radiol 21:1465\u20131474","journal-title":"Acad Radiol"},{"key":"4063_CR19","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/S1001-9294(13)60005-X","volume":"27","author":"X Wang","year":"2013","unstructured":"Wang X, Jin Z-Y, Xue H-D et al (2013) Evaluation of Normal Adrenal Gland Volume by 64-slice CT. Chin Med Sci J 27:220\u2013224","journal-title":"Chin Med Sci J"},{"key":"4063_CR20","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/BF03344090","volume":"29","author":"AF Godoy-Matos","year":"2006","unstructured":"Godoy-Matos AF, Vieira AR, Moreira RO et al (2006) The potential role of increased adrenal volume in the pathophysiology of obesity-related type 2 diabetes. J Endocrinol Invest 29:159\u2013163","journal-title":"J Endocrinol Invest"},{"key":"4063_CR21","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0009-9260(05)81739-8","volume":"49","author":"JM Vincent","year":"1994","unstructured":"Vincent JM, Morrison ID, Armstrong P, Reznek RH (1994) The size of normal adrenal glands on computed tomography. Clin Radiol 49:453\u2013455","journal-title":"Clin Radiol"},{"key":"4063_CR22","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1037\/0033-2909.86.2.420","volume":"86","author":"PE Shrout","year":"1979","unstructured":"Shrout PE, Fleiss JL (1979) Intraclass correlations: uses in assessing rater reliability. Psychol Bull 86:420\u2013428","journal-title":"Psychol Bull"},{"key":"4063_CR23","first-page":"127","volume":"86","author":"DV Cicchetti","year":"1981","unstructured":"Cicchetti DV, Sparrow SA (1981) Developing criteria for establishing interrater reliability of specific items: applications to assessment of adaptive behavior. Am J Ment Defic 86:127\u2013137","journal-title":"Am J Ment Defic"},{"key":"4063_CR24","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1111\/cen.12193","volume":"79","author":"EM Freel","year":"2013","unstructured":"Freel EM, Nicholas RS, Sudarshan T et al (2013) Assessment of the accuracy and reproducibility of adrenal volume measurements using MRI and its relationship with corticosteroid phenotype: a normal volunteer pilot study. Clin Endocrinol (Oxf) 79:484\u2013490","journal-title":"Clin Endocrinol (Oxf)"},{"key":"4063_CR25","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1210\/jc.2006-2674","volume":"92","author":"SH Golden","year":"2007","unstructured":"Golden SH, Malhotra S, Wand GS, Brancati FL, Ford D, Horton K (2007) Adrenal gland volume and dexamethasone-suppressed cortisol correlate with total daily salivary cortisol in African-American women. J Clin Endocrinol Metab 92:1358\u20131363","journal-title":"J Clin Endocrinol Metab"},{"key":"4063_CR26","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/2251-6581-12-9","volume":"12","author":"Z Elahi-Moghaddam","year":"2013","unstructured":"Elahi-Moghaddam Z, Behnam-Rassouli M, Mahdavi-Shahri N, Hajinejad-Boshroue R, Khajouee E (2013) Comparative study on the effects of type 1 and type 2 diabetes on structural changes and hormonal output of the adrenal cortex in male Wistar rats. J Diabetes Metab Disord 12:9\u201315","journal-title":"J Diabetes Metab Disord"},{"key":"4063_CR27","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/0006-3223(94)91212-2","volume":"36","author":"E Szigethy","year":"1994","unstructured":"Szigethy E, Conwell Y, Forbes NT, Cox C, Caine ED (1994) Adrenal weight and morphology in victims of completed suicide. Biol Psychiatry 36:374\u2013380","journal-title":"Biol Psychiatry"},{"key":"4063_CR28","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1001\/archpsyc.1992.01820050048008","volume":"49","author":"CB Nemeroff","year":"1992","unstructured":"Nemeroff CB, Krishnan KR, Reed D, Leder R, Beam C, Dunnick NR (1992) Adrenal gland enlargement in major depression. A computed tomographic study. Arch Gen Psychiatry 49:384\u2013387","journal-title":"Arch Gen Psychiatry"},{"key":"4063_CR29","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0006-3223(95)00358-4","volume":"40","author":"RT Rubin","year":"1996","unstructured":"Rubin RT, Phillips JJ, McCracken JT, Sadow TF (1996) Adrenal gland volume in major depression: relationship to basal and stimulated pituitary-adrenal cortical axis function. Biol Psychiatry 40:89\u201397","journal-title":"Biol Psychiatry"},{"key":"4063_CR30","doi-asserted-by":"crossref","first-page":"117","DOI":"10.3109\/02841850903352620","volume":"51","author":"LA Grant","year":"2010","unstructured":"Grant LA, Napolitano A, Miller S, Stephens K, McHugh SM, Dixon AK (2010) A pilot study to assess the feasibility of measurement of adrenal gland volume by magnetic resonance imaging. Acta Radiol 51:117\u2013120","journal-title":"Acta Radiol"},{"key":"4063_CR31","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1007\/s12020-011-9445-6","volume":"40","author":"C Davenport","year":"2011","unstructured":"Davenport C, Liew A, Doherty B et al (2011) The prevalence of adrenal incidentaloma in routine clinical practice. Endocrine 40:80\u201383","journal-title":"Endocrine"},{"key":"4063_CR32","doi-asserted-by":"crossref","first-page":"174","DOI":"10.4103\/0971-6203.62130","volume":"35","author":"ND Prionas","year":"2010","unstructured":"Prionas ND, Gillen MA, Boone JM (2010) Longitudinal volume analysis from computed tomography: Reproducibility using adrenal glands as surrogate tumors. J Med Phys 35:174\u2013180","journal-title":"J Med Phys"},{"key":"4063_CR33","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1053\/j.semnuclmed.2007.02.001","volume":"37","author":"JM Meier","year":"2007","unstructured":"Meier JM, Alavi A, Iruvuri S et al (2007) Assessment of age-related changes in abdominal organ structure and function with computed tomography and positron emission tomography. Semin Nucl Med 37:154\u2013172","journal-title":"Semin Nucl Med"},{"key":"4063_CR34","doi-asserted-by":"crossref","unstructured":"Hornsby PJ (2004) Aging of the human adrenal cortex. Sci Aging Knowledge Environ 2004:re6","DOI":"10.1126\/sageke.2004.35.re6"},{"key":"4063_CR35","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1001\/archinte.1948.00220190045004","volume":"81","author":"RR Commons","year":"1948","unstructured":"Commons RR, Callaway CP (1948) Adenomas of the adrenal cortex. Arch Intern Med (Chic) 81:37\u201341","journal-title":"Arch Intern Med (Chic)"},{"key":"4063_CR36","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1097\/00006842-200203000-00010","volume":"64","author":"B Weber-Hamann","year":"2002","unstructured":"Weber-Hamann B, Hentschel F, Kniest A et al (2002) Hypercortisolemic depression is associated with increased intra-abdominal fat. Psychosom Med 64:274\u2013277","journal-title":"Psychosom Med"},{"key":"4063_CR37","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1055\/s-2007-982518","volume":"39","author":"B Ludescher","year":"2007","unstructured":"Ludescher B, Najib A, Baar S et al (2007) Gender specific correlations of adrenal gland size and body fat distribution: a whole body MRI study. Horm Metab Res 39:515\u2013518","journal-title":"Horm Metab Res"},{"key":"4063_CR38","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1097\/00006842-200009000-00005","volume":"62","author":"ES Epel","year":"2000","unstructured":"Epel ES, McEwen B, Seeman T et al (2000) Stress and body shape: stress-induced cortisol secretion is consistently greater among women with central fat. Psychosom Med 62:623\u2013632","journal-title":"Psychosom Med"},{"key":"4063_CR39","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/S1056-8727(97)00006-8","volume":"12","author":"MS Roy","year":"1998","unstructured":"Roy MS, Roy A, Brown S (1998) Increased urinary-free cortisol outputs in diabetic patients. J Diabetes Complications 12:24\u201327","journal-title":"J Diabetes Complications"},{"key":"4063_CR40","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1016\/j.metabol.2006.04.010","volume":"55","author":"I Chiodini","year":"2006","unstructured":"Chiodini I, Di Lembo S, Morelli V et al (2006) Hypothalamic\u2013pituitary\u2013adrenal activity in type 2 diabetes mellitus: role of autonomic imbalance. Metabolism 55:1135\u20131140","journal-title":"Metabolism"},{"key":"4063_CR41","first-page":"448","volume":"34","author":"HC Becker","year":"2012","unstructured":"Becker HC (2012) Effects of alcohol dependence and withdrawal on stress responsiveness and alcohol consumption. Alcohol Res 34:448\u2013458","journal-title":"Alcohol Res"},{"key":"4063_CR42","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0091-3057(80)80021-9","volume":"13","author":"RH Ylikahri","year":"1980","unstructured":"Ylikahri RH, Huttunen MO, H\u00e4rk\u00f6nen M (1980) Hormonal changes during alcohol intoxication and withdrawal. Pharmacol Biochem Behav 13:131\u2013137","journal-title":"Pharmacol Biochem Behav"},{"key":"4063_CR43","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1093\/alcalc\/agr054","volume":"46","author":"D Diki\u0107","year":"2011","unstructured":"Diki\u0107 D, Bude\u010d M, Vranje\u0161-Duri\u0107 S, Koko V, Vignjevi\u0107 S, Mitrovi\u0107 O (2011) The acute effect of ethanol on adrenal cortex in female rats\u2014possible role of nitric oxide. Alcohol 46:523\u2013528","journal-title":"Alcohol"},{"key":"4063_CR44","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.semarthrit.2013.04.008","volume":"43","author":"RH Straub","year":"2013","unstructured":"Straub RH, Bijlsma JWJ, Masi A, Cutolo M (2013) Role of neuroendocrine and neuroimmune mechanisms in chronic inflammatory rheumatic diseases\u2014the 10-year update. Semin Arthritis Rheum 43:392\u2013404","journal-title":"Semin Arthritis Rheum"},{"key":"4063_CR45","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1111\/j.1749-6632.2000.tb05449.x","volume":"917","author":"M Cutolo","year":"2000","unstructured":"Cutolo M, Villaggio B, Foppiani L et al (2000) The hypothalamic\u2013pituitary\u2013adrenal and gonadal axes in rheumatoid arthritis. Ann N Y Acad Sci 917:835\u2013843","journal-title":"Ann N Y Acad Sci"}],"container-title":["European Radiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-015-4063-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00330-015-4063-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-015-4063-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T12:00:12Z","timestamp":1559044812000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00330-015-4063-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10,30]]},"references-count":45,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["4063"],"URL":"https:\/\/doi.org\/10.1007\/s00330-015-4063-y","relation":{},"ISSN":["0938-7994","1432-1084"],"issn-type":[{"value":"0938-7994","type":"print"},{"value":"1432-1084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,10,30]]}}}