{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:11:11Z","timestamp":1791976271461,"version":"4.4.0"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2016,12,5]],"date-time":"2016-12-05T00:00:00Z","timestamp":1480896000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"NIH\/NCI Cancer Center Support Grant","award":["P30 CA008748"],"award-info":[{"award-number":["P30 CA008748"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Radiol"],"published-print":{"date-parts":[[2017,7]]},"DOI":"10.1007\/s00330-016-4623-9","type":"journal-article","created":{"date-parts":[[2016,12,5]],"date-time":"2016-12-05T09:14:22Z","timestamp":1480929262000},"page":"2903-2915","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":155,"title":["Differentiation of Uterine Leiomyosarcoma from Atypical Leiomyoma: Diagnostic Accuracy of Qualitative MR Imaging Features and Feasibility of Texture Analysis"],"prefix":"10.1007","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3626-4502","authenticated-orcid":false,"given":"Yulia","family":"Lakhman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harini","family":"Veeraraghavan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Chaim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Feier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debra A.","family":"Goldman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaya S.","family":"Moskowitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Nougaret","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramon E.","family":"Sosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hebert Alberto","family":"Vargas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A.","family":"Soslow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadeem R.","family":"Abu-Rustum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hedvig","family":"Hricak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evis","family":"Sala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,12,5]]},"reference":[{"key":"4623_CR1","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1097\/01.grf.0000159538.27221.8c","volume":"48","author":"GL Ryan","year":"2005","unstructured":"Ryan GL, Syrop CH, Van Voorhis BJ (2005) Role, epidemiology, and natural history of benign uterine mass lesions. Clin Obstet Gynecol 48:312\u2013324","journal-title":"Clin Obstet Gynecol"},{"key":"4623_CR2","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1097\/01.AOG.0000136079.62513.39","volume":"104","author":"EE Wallach","year":"2004","unstructured":"Wallach EE, Vlahos NF (2004) Uterine myomas: an overview of development, clinical features, and management. Obstet Gynecol 104:393\u2013406","journal-title":"Obstet Gynecol"},{"key":"4623_CR3","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.ogc.2014.09.009","volume":"42","author":"C Owen","year":"2015","unstructured":"Owen C, Armstrong AY (2015) Clinical management of leiomyoma. Obstet Gynecol Clin N Am 42:67\u201385","journal-title":"Obstet Gynecol Clin N Am"},{"key":"4623_CR4","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.bpobgyn.2011.07.002","volume":"25","author":"TI Wu","year":"2011","unstructured":"Wu TI, Yen TC, Lai CH (2011) Clinical presentation and diagnosis of uterine sarcoma, including imaging. Best Pract Res Clin Obstet Gynaecol 25:681\u2013689","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"4623_CR5","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.ygyno.2009.09.023","volume":"116","author":"E D'Angelo","year":"2010","unstructured":"D'Angelo E, Prat J (2010) Uterine sarcomas: a review. Gynecol Oncol 116:131\u2013139","journal-title":"Gynecol Oncol"},{"key":"4623_CR6","doi-asserted-by":"crossref","first-page":"4","DOI":"10.5152\/dir.2014.14053","volume":"21","author":"P Santos","year":"2015","unstructured":"Santos P, Cunha TM (2015) Uterine sarcomas: clinical presentation and MRI features. Diagn Interv Radiol 21:4\u20139","journal-title":"Diagn Interv Radiol"},{"key":"4623_CR7","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1148\/radiology.158.2.3753623","volume":"158","author":"H Hricak","year":"1986","unstructured":"Hricak H, Tscholakoff D, Heinrichs L et al (1986) Uterine leiomyomas: correlation of MR, histopathologic findings, and symptoms. Radiology 158:385\u2013391","journal-title":"Radiology"},{"key":"4623_CR8","doi-asserted-by":"crossref","unstructured":"Ueda H, Togashi K, Konishi I et al (1999) Unusual appearances of uterine leiomyomas: MR imaging findings and their histopathologic backgrounds. Radiographics 19 Spec No:S131-145","DOI":"10.1148\/radiographics.19.suppl_1.g99oc04s131"},{"key":"4623_CR9","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/S0015-0282(98)00193-9","volume":"70","author":"LB Schwartz","year":"1998","unstructured":"Schwartz LB, Zawin M, Carcangiu ML, Lange R, McCarthy S (1998) Does pelvic magnetic resonance imaging differentiate among the histologic subtypes of uterine leiomyomata? Fertil Steril 70:580\u2013587","journal-title":"Fertil Steril"},{"key":"4623_CR10","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.2214\/ajr.177.6.1771307","volume":"177","author":"A Sahdev","year":"2001","unstructured":"Sahdev A, Sohaib SA, Jacobs I, Shepherd JH, Oram DH, Reznek RH (2001) MR imaging of uterine sarcomas. AJR Am J Roentgenol 177:1307\u20131311","journal-title":"AJR Am J Roentgenol"},{"key":"4623_CR11","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1046\/j.1525-1438.2002.01086.x","volume":"12","author":"A Goto","year":"2002","unstructured":"Goto A, Takeuchi S, Sugimura K, Maruo T (2002) Usefulness of Gd-DTPA contrast-enhanced dynamic MRI and serum determination of LDH and its isozymes in the differential diagnosis of leiomyosarcoma from degenerated leiomyoma of the uterus. Int J Gynecol Cancer 12:354\u2013361","journal-title":"Int J Gynecol Cancer"},{"key":"4623_CR12","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1002\/jmri.20207","volume":"20","author":"YO Tanaka","year":"2004","unstructured":"Tanaka YO, Nishida M, Tsunoda H, Okamoto Y, Yoshikawa H (2004) Smooth muscle tumors of uncertain malignant potential and leiomyosarcomas of the uterus: MR findings. J Magn Reson Imaging 20:998\u20131007","journal-title":"J Magn Reson Imaging"},{"key":"4623_CR13","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1007\/s00330-007-0787-7","volume":"18","author":"K Tamai","year":"2008","unstructured":"Tamai K, Koyama T, Saga T et al (2008) The utility of diffusion-weighted MR imaging for differentiating uterine sarcomas from benign leiomyomas. Eur Radiol 18:723\u2013730","journal-title":"Eur Radiol"},{"key":"4623_CR14","doi-asserted-by":"crossref","first-page":"2756","DOI":"10.1007\/s00330-009-1471-x","volume":"19","author":"T Namimoto","year":"2009","unstructured":"Namimoto T, Yamashita Y, Awai K et al (2009) Combined use of T2-weighted and diffusion-weighted 3-T MR imaging for differentiating uterine sarcomas from benign leiomyomas. Eur Radiol 19:2756\u20132764","journal-title":"Eur Radiol"},{"key":"4623_CR15","doi-asserted-by":"crossref","first-page":"2306","DOI":"10.1007\/s00330-013-2819-9","volume":"23","author":"I Thomassin-Naggara","year":"2013","unstructured":"Thomassin-Naggara I, Dechoux S, Bonneau C et al (2013) How to differentiate benign from malignant myometrial tumours using MR imaging. Eur Radiol 23:2306\u20132314","journal-title":"Eur Radiol"},{"key":"4623_CR16","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.ejrad.2009.03.005","volume":"74","author":"D Cornfeld","year":"2010","unstructured":"Cornfeld D, Israel G, Martel M, Weinreb J, Schwartz P, McCarthy S (2010) MRI appearance of mesenchymal tumors of the uterus. Eur J Radiol 74:241\u2013249","journal-title":"Eur J Radiol"},{"key":"4623_CR17","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1007\/s00261-014-0324-5","volume":"40","author":"A Tasaki","year":"2015","unstructured":"Tasaki A, Asatani MO, Umezu H et al (2015) Differential diagnosis of uterine smooth muscle tumors using diffusion-weighted imaging: correlations with the apparent diffusion coefficient and cell density. Abdom Imaging 40:1742\u20131752","journal-title":"Abdom Imaging"},{"key":"4623_CR18","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1186\/s40064-015-1318-7","volume":"4","author":"T Nagai","year":"2015","unstructured":"Nagai T, Takai Y, Akahori T et al (2015) Highly improved accuracy of the revised PREoperative sarcoma score (rPRESS) in the decision of performing surgery for patients presenting with a uterine mass. Springerplus 4:520","journal-title":"Springerplus"},{"key":"4623_CR19","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1016\/j.acra.2014.07.023","volume":"21","author":"SP Raman","year":"2014","unstructured":"Raman SP, Chen Y, Schroeder JL, Huang P, Fishman EK (2014) CT texture analysis of renal masses: pilot study using random forest classification for prediction of pathology. Acad Radiol 21:1587\u20131596","journal-title":"Acad Radiol"},{"key":"4623_CR20","first-page":"383","volume":"39","author":"SP Raman","year":"2015","unstructured":"Raman SP, Schroeder JL, Huang P et al (2015) Preliminary data using computed tomography texture analysis for the classification of hypervascular liver lesions: generation of a predictive model on the basis of quantitative spatial frequency measurements--a work in progress. J Comput Assist Tomogr 39:383\u2013395","journal-title":"J Comput Assist Tomogr"},{"key":"4623_CR21","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1016\/j.acra.2015.04.004","volume":"22","author":"L Yan","year":"2015","unstructured":"Yan L, Liu Z, Wang G et al (2015) Angiomyolipoma with minimal fat: differentiation from clear cell renal cell carcinoma and papillary renal cell carcinoma by texture analysis on CT images. Acad Radiol 22:1115\u20131121","journal-title":"Acad Radiol"},{"key":"4623_CR22","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1148\/radiol.2015142215","volume":"276","author":"T Hodgdon","year":"2015","unstructured":"Hodgdon T, McInnes MD, Schieda N, Flood TA, Lamb L, Thornhill RE (2015) Can Quantitative CT Texture Analysis be Used to Differentiate Fat-poor Renal Angiomyolipoma from Renal Cell Carcinoma on Unenhanced CT Images? Radiology 276:787\u2013796","journal-title":"Radiology"},{"key":"4623_CR23","doi-asserted-by":"crossref","first-page":"2840","DOI":"10.1007\/s00330-015-3701-8","volume":"25","author":"A Wibmer","year":"2015","unstructured":"Wibmer A, Hricak H, Gondo T et al (2015) Haralick texture analysis of prostate MRI: utility for differentiating non-cancerous prostate from prostate cancer and differentiating prostate cancers with different Gleason scores. Eur Radiol 25:2840\u20132850","journal-title":"Eur Radiol"},{"key":"4623_CR24","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1097\/00000478-199406000-00001","volume":"18","author":"SW Bell","year":"1994","unstructured":"Bell SW, Kempson RL, Hendrickson MR (1994) Problematic uterine smooth muscle neoplasms. A clinicopathologic study of 213 cases. Am J Surg Pathol 18:535\u2013558","journal-title":"Am J Surg Pathol"},{"key":"4623_CR25","volume-title":"Pathology and genetics of tumours of the breast and female genital organs","author":"Tavassoli FA, Devilee P, International Agency for Research on C, World Health O","year":"2003","unstructured":"Tavassoli FA, Devilee P, International Agency for Research on C, World Health O (2003) Pathology and genetics of tumours of the breast and female genital organs. IAPS Press, Lyon"},{"key":"4623_CR26","first-page":"586","volume":"85","author":"TS Yoo","year":"2002","unstructured":"Yoo TS, Ackerman MJ, Lorensen WE et al (2002) Engineering and algorithm design for an image processing Api: a technical report on ITK--the Insight Toolkit. Stud Health Technol Inform 85:586\u2013592","journal-title":"Stud Health Technol Inform"},{"key":"4623_CR27","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1109\/42.836373","volume":"19","author":"LG Nyul","year":"2000","unstructured":"Nyul LG, Udupa JK, Zhang X (2000) New variants of a method of MRI scale standardization. IEEE Trans Med Imaging 19:143\u2013150","journal-title":"IEEE Trans Med Imaging"},{"key":"4623_CR28","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1364\/JOSAA.2.001160","volume":"2","author":"JG Daugman","year":"1985","unstructured":"Daugman JG (1985) Uncertainty relation for resolution in space, spatial frequency, and orientation optimized by two-dimensional visual cortical filters. J Opt Soc Am A 2:1160\u20131169","journal-title":"J Opt Soc Am A"},{"key":"4623_CR29","doi-asserted-by":"crossref","unstructured":"Haralick RM, Shanmuga K, Dinstein I (1973) Textural features for image classification. Ieee Transactions on Systems Man and Cybernetics SMC3:610-621","DOI":"10.1109\/TSMC.1973.4309314"},{"key":"4623_CR30","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/0734-189X(84)90197-X","volume":"25","author":"RW Conners","year":"1984","unstructured":"Conners RW, Trivedi MM, Harlow CA (1984) Segmentation of a high-resolution urban scene using texture operators. Comput Vis Graph Image Process 25:273\u2013310","journal-title":"Comput Vis Graph Image Process"},{"key":"4623_CR31","first-page":"1601","volume":"17","author":"LPP Zelnik-Manor","year":"2005","unstructured":"Zelnik-Manor LPP (2005) Self-tuning spectral clustering. Adv Neural Inf Proces Syst 17:1601\u20131608","journal-title":"Adv Neural Inf Proces Syst"},{"key":"4623_CR32","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2307\/2529310","volume":"33","author":"JR Landis","year":"1977","unstructured":"Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159\u2013174","journal-title":"Biometrics"},{"key":"4623_CR33","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s10397-015-0878-4","volume":"12","author":"H Brolmann","year":"2015","unstructured":"Brolmann H, Tanos V, Grimbizis G et al (2015) Options on fibroid morcellation: a literature review. Gynecol Surg 12:3\u201315","journal-title":"Gynecol Surg"},{"key":"4623_CR34","first-page":"370","volume":"27","author":"CM Juang","year":"2006","unstructured":"Juang CM, Yen MS, Horng HC, Twu NF, Yu HC, Hsu WL (2006) Potential role of preoperative serum CA125 for the differential diagnosis between uterine leiomyoma and uterine leiomyosarcoma. Eur J Gynaecol Oncol 27:370\u2013374","journal-title":"Eur J Gynaecol Oncol"}],"container-title":["European Radiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00330-016-4623-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-016-4623-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-016-4623-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,8]],"date-time":"2017-06-08T07:09:38Z","timestamp":1496905778000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00330-016-4623-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,5]]},"references-count":34,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["4623"],"URL":"https:\/\/doi.org\/10.1007\/s00330-016-4623-9","relation":{},"ISSN":["0938-7994","1432-1084"],"issn-type":[{"value":"0938-7994","type":"print"},{"value":"1432-1084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,5]]}}}