{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T20:07:20Z","timestamp":1790539640474,"version":"4.1.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2017,3,20]],"date-time":"2017-03-20T00:00:00Z","timestamp":1489968000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100010109","name":"Medical University of Graz","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100010109","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Radiol"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1007\/s00330-017-4788-x","type":"journal-article","created":{"date-parts":[[2017,3,20]],"date-time":"2017-03-20T16:37:14Z","timestamp":1490027834000},"page":"4173-4180","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["CT perfusion imaging of the liver and the spleen in patients with cirrhosis: Is there a correlation between perfusion and portal venous hypertension?"],"prefix":"10.1007","volume":"27","author":[{"given":"Emina","family":"Talaki\u0107","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Schaffellner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Kniepeiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helmut","family":"Mueller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudolf","family":"Stauber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franz","family":"Quehenberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helmut","family":"Schoellnast","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,3,20]]},"reference":[{"key":"4788_CR1","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1002\/hep.24129","volume":"53","author":"D Thabut","year":"2011","unstructured":"Thabut D, Moreau R, Lebrec D (2011) Noninvasive assessment of portal hypertension in patients with cirrhosis. Hepatology 53:683\u2013694","journal-title":"Hepatology"},{"key":"4788_CR2","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0950-3528(97)90037-3","volume":"11","author":"D Lebrec","year":"1997","unstructured":"Lebrec D, Sogni P, Vilgrain V (1997) Evaluation of patients with portal hypertension. Baillieres Clin Gastroenterol 11:221\u2013241","journal-title":"Baillieres Clin Gastroenterol"},{"key":"4788_CR3","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/j.1440-1746.1997.tb00401.x","volume":"12","author":"A Gadano","year":"1997","unstructured":"Gadano A, Hadengue A, Vachiery F et al (1997) Relationship between hepatic blood flow, liver tests, haemodynamic values and clinical characteristics in patients with chronic liver disease. J Gastroenterol Hepatol 12:167\u2013171","journal-title":"J Gastroenterol Hepatol"},{"key":"4788_CR4","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1002\/hep.1840050313","volume":"5","author":"G Garcia-Tsao","year":"1985","unstructured":"Garcia-Tsao G, Groszmann RJ, Fisher RL, Conn HO, Atterbury CE, Glickman M (1985) Portal pressure, presence of gastroesophageal varices and variceal bleeding. Hepatology 5:419\u2013424","journal-title":"Hepatology"},{"key":"4788_CR5","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1016\/0016-5085(80)90905-1","volume":"79","author":"D Lebrec","year":"1980","unstructured":"Lebrec D, De Fleury P, Rueff B, Nahum H, Benhamou JP (1980) Portal hypertension, size of esophageal varices, and risk of gastrointestinal bleeding in alcoholic cirrhosis. Gastroenterology 79:1139\u20131144","journal-title":"Gastroenterology"},{"key":"4788_CR6","doi-asserted-by":"crossref","first-page":"2254","DOI":"10.1056\/NEJMoa044456","volume":"353","author":"RJ Groszmann","year":"2005","unstructured":"Groszmann RJ, Garcia-Tsao G, Bosch J et al (2005) Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis. N Engl J Med 353:2254\u20132261","journal-title":"N Engl J Med"},{"key":"4788_CR7","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1053\/j.gastro.2007.05.024","volume":"133","author":"C Ripoll","year":"2007","unstructured":"Ripoll C, Groszmann R, Garcia-Tsao G et al (2007) Hepatic venous pressure gradient predicts clinical decompensation in patients with compensated cirrhosis. Gastroenterology 133:481\u2013488","journal-title":"Gastroenterology"},{"key":"4788_CR8","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/j.jhep.2009.01.014","volume":"50","author":"C Ripoll","year":"2009","unstructured":"Ripoll C, Groszmann RJ, Garcia-Tsao G et al (2009) Hepatic venous pressure gradient predicts development of hepatocellular carcinoma independently of severity of cirrhosis. J Hepatol 50:923\u2013928","journal-title":"J Hepatol"},{"key":"4788_CR9","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/0016-5085(92)90185-2","volume":"102","author":"C Merkel","year":"1992","unstructured":"Merkel C, Bolognesi M, Bellon S et al (1992) Prognostic usefulness of hepatic vein catheterization in patients with cirrhosis and esophageal varices. Gastroenterology 102:973\u2013979","journal-title":"Gastroenterology"},{"key":"4788_CR10","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1002\/hep.28031","volume":"62","author":"G Silva-Junior","year":"2015","unstructured":"Silva-Junior G, Baiges A, Turon F et al (2015) The prognostic value of hepatic venous pressure gradient in patients with cirrhosis is highly dependent on the accuracy of the technique. Hepatology 62:1584\u20131592","journal-title":"Hepatology"},{"key":"4788_CR11","doi-asserted-by":"crossref","first-page":"3465","DOI":"10.3748\/wjg.v11.i22.3465","volume":"11","author":"S Guan","year":"2005","unstructured":"Guan S, Zhao WD, Zhou KR, Peng WJ, Mao J, Tang F (2005) CT perfusion at early stage of hepatic diffuse disease. World J Gastroenterol 11:3465\u20133467","journal-title":"World J Gastroenterol"},{"key":"4788_CR12","first-page":"677","volume":"16","author":"K Hashimoto","year":"2006","unstructured":"Hashimoto K, Murakami T, Dono K et al (2006) Assessment of the severity of liver disease and fibrotic change: the usefulness of hepatic CT perfusion imaging. Oncol Rep 16:677\u2013683","journal-title":"Oncol Rep"},{"key":"4788_CR13","doi-asserted-by":"crossref","first-page":"667","DOI":"10.2214\/ajr.176.3.1760667","volume":"176","author":"BE Beers Van","year":"2001","unstructured":"Van Beers BE, Leconte I, Materne R, Smith AM, Jamart J, Horsmans Y (2001) Hepatic perfusion parameters in chronic liver disease: dynamic CT measurements correlated with disease severity. AJR Am J Roentgenol 176:667\u2013673","journal-title":"AJR Am J Roentgenol"},{"key":"4788_CR14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.rcl.2015.09.002","volume":"54","author":"D Fleischmann","year":"2016","unstructured":"Fleischmann D, Chin AS, Molvin L, Wang J, Hallett R (2016) Computed Tomography Angiography: A Review and Technical Update. Radiol Clin North Am 54:1\u201312","journal-title":"Radiol Clin North Am"},{"key":"4788_CR15","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1259\/bjr\/13564625","volume":"76","author":"KA Miles","year":"2003","unstructured":"Miles KA, Griffiths MR (2003) Perfusion CT: a worthwhile enhancement? Br J Radiol 76:220\u2013231","journal-title":"Br J Radiol"},{"key":"4788_CR16","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-016-4277-7","author":"MA Fischer","year":"2016","unstructured":"Fischer MA, Brehmer K, Svensson A, Aspelin P, Brismar TB (2016) Renal versus splenic maximum slope based perfusion CT modelling in patients with portal-hypertension. Eur Radiol. doi: 10.1007\/s00330-016-4277-7","journal-title":"Eur Radiol"},{"key":"4788_CR17","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1002\/hep.20062","volume":"39","author":"RJ Groszmann","year":"2004","unstructured":"Groszmann RJ, Wongcharatrawee S (2004) The hepatic venous pressure gradient: anything worth doing should be done right. Hepatology 39:280\u2013282","journal-title":"Hepatology"},{"key":"4788_CR18","doi-asserted-by":"crossref","first-page":"153","DOI":"10.2214\/ajr.170.1.9423623","volume":"170","author":"Y Tsushima","year":"1998","unstructured":"Tsushima Y, Koizumi J, Yokoyama H, Takeda A, Kusano S (1998) Evaluation of portal pressure by splenic perfusion measurement using dynamic CT. AJR Am J Roentgenol 170:153\u2013155","journal-title":"AJR Am J Roentgenol"},{"key":"4788_CR19","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S1076-6332(97)80155-9","volume":"4","author":"MJ Blomley","year":"1997","unstructured":"Blomley MJ, Kormano M, Coulden R, Lim-Dunham J, Dawson P, Lipton MJ (1997) Splenic blood flow: evaluation with computed tomography. Acad Radiol 4:13\u201320","journal-title":"Acad Radiol"},{"key":"4788_CR20","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1177\/0284185113503322","volume":"55","author":"AW Sauter","year":"2014","unstructured":"Sauter AW, Spira D, Schulze M, Horger MS (2014) Explanations for the heterogeneity of splenic enhancement derived from blood flow kinetic measurements using dynamic contrast-enhanced CT (DCE-CT). Acta Radiol 55:645\u2013653","journal-title":"Acta Radiol"},{"key":"4788_CR21","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1097\/00003072-198105000-00008","volume":"6","author":"HJ Biersack","year":"1981","unstructured":"Biersack HJ, Torres J, Thelen M, Monzon O, Winkler C (1981) Determination of liver and spleen perfusion by quantitative sequential scintigraphy: results in normal subjects and in patients with portal hypertension. Clin Nucl Med 6:218\u2013220","journal-title":"Clin Nucl Med"},{"key":"4788_CR22","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1097\/00004836-199303000-00017","volume":"16","author":"T Dao","year":"1993","unstructured":"Dao T, Elfadel S, Bouvard G et al (1993) Assessment of portal contribution to liver perfusion by quantitative sequential scintigraphy and Doppler ultrasound in alcoholic cirrhosis. Diagnostic value in the detection of portal hypertension. J Clin Gastroenterol 16:160\u2013167","journal-title":"J Clin Gastroenterol"},{"key":"4788_CR23","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/BF00253798","volume":"15","author":"M Gianpaolo","year":"1989","unstructured":"Gianpaolo M, Massimo B, Enzo S, Corrado M (1989) Assessment of liver circulation by quantitative scintiangiography: evaluation of the relative contribution of the hepatic arterial and portal venous blood flows to liver perfusion. Eur J Nucl Med 15:211\u2013216","journal-title":"Eur J Nucl Med"},{"key":"4788_CR24","volume":"10","author":"WK Jeong","year":"2015","unstructured":"Jeong WK, Kim TY, Sohn JH, Kim Y, Kim J (2015) Severe portal hypertension in cirrhosis: evaluation of perfusion parameters with contrast-enhanced ultrasonography. PLoS One 10, e0121601","journal-title":"PLoS One"},{"key":"4788_CR25","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1148\/radiol.2292021128","volume":"229","author":"L Annet","year":"2003","unstructured":"Annet L, Materne R, Danse E, Jamart J, Horsmans Y, Van Beers BE (2003) Hepatic flow parameters measured with MR imaging and Doppler US: correlations with degree of cirrhosis and portal hypertension. Radiology 229:409\u2013414","journal-title":"Radiology"},{"key":"4788_CR26","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1007\/s00330-015-3991-x","volume":"26","author":"H Gouya","year":"2016","unstructured":"Gouya H, Grabar S, Vignaux O et al (2016) Portal hypertension in patients with cirrhosis: indirect assessment of hepatic venous pressure gradient by measuring azygos flow with 2D-cine phase-contrast magnetic resonance imaging. Eur Radiol 26:1981\u20131990","journal-title":"Eur Radiol"},{"key":"4788_CR27","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1007\/s00261-015-0614-6","volume":"41","author":"S Kihira","year":"2016","unstructured":"Kihira S, Kagen AC, Vasudevan P et al (2016) Non-invasive prediction of portal pressures using CT and MRI in chronic liver disease. Abdom Radiol (NY) 41:42\u201349","journal-title":"Abdom Radiol (NY)"},{"key":"4788_CR28","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-016-4648-0","author":"PJ Pickhardt","year":"2016","unstructured":"Pickhardt PJ, Malecki K, Hunt OF et al (2016) Hepatosplenic volumetric assessment at MDCT for staging liver fibrosis. Eur Radiol. doi: 10.1007\/s00330-016-4648-0","journal-title":"Eur Radiol"}],"container-title":["European Radiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00330-017-4788-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-017-4788-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-017-4788-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,17]],"date-time":"2020-05-17T18:28:35Z","timestamp":1589740115000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00330-017-4788-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,20]]},"references-count":28,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["4788"],"URL":"https:\/\/doi.org\/10.1007\/s00330-017-4788-x","relation":{},"ISSN":["0938-7994","1432-1084"],"issn-type":[{"value":"0938-7994","type":"print"},{"value":"1432-1084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,20]]}}}