{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T23:22:23Z","timestamp":1788218543527,"version":"build-2803163510"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2018,5,7]],"date-time":"2018-05-07T00:00:00Z","timestamp":1525651200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Radiol"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1007\/s00330-018-5437-8","type":"journal-article","created":{"date-parts":[[2018,5,7]],"date-time":"2018-05-07T17:13:29Z","timestamp":1525713209000},"page":"4900-4908","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":49,"title":["Diagnostic accuracy of 3T magnetic resonance imaging in the preoperative localisation of parathyroid adenomas: comparison with ultrasound and 99mTc-sestamibi scans"],"prefix":"10.1007","volume":"28","author":[{"given":"Renato","family":"Argir\u00f2","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6894-3433","authenticated-orcid":false,"given":"Daniele","family":"Diacinti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatrice","family":"Sacconi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"Iannarelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Diacinti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristiana","family":"Cipriani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Pisani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabetta","family":"Romagnoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Biffoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cira","family":"Di Gioia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Pepe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Bezzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Letizia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Minisola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Catalano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,5,7]]},"reference":[{"key":"5437_CR1","doi-asserted-by":"publisher","first-page":"1232","DOI":"10.1016\/j.surg.2013.06.051","volume":"154","author":"DM Press","year":"2013","unstructured":"Press DM, Siperstein AE, Berber E et al (2013) The prevalence of undiagnosed and unrecognised hyperparathyroidism: a population-based analysis from the electronic medical record. Surgery 154:1232\u20131237","journal-title":"Surgery"},{"key":"5437_CR2","doi-asserted-by":"publisher","first-page":"1128","DOI":"10.1097\/01.MLG.0000163745.57542.FE","volume":"115","author":"B Abboud","year":"2005","unstructured":"Abboud B, Sleilaty G, Helou E et al (2005) Existence and anatomic distribution of double parathyroid adenoma. Laryngoscope 115:1128\u20131131","journal-title":"Laryngoscope"},{"issue":"4","key":"5437_CR3","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1097\/01.sla.0000120072.85692.a7","volume":"239","author":"MS Eigelberger","year":"2004","unstructured":"Eigelberger MS, Cheah WK, Ituarte PH et al (2004) The NIH criteria for parathyroidectomy in asymptomatic primary hyperparathyroidism: are they too limited? Ann Surg 239(4):528\u2013535","journal-title":"Ann Surg"},{"issue":"10","key":"5437_CR4","doi-asserted-by":"publisher","first-page":"3580","DOI":"10.1210\/jc.2014-1415","volume":"99","author":"SJ Silverberg","year":"2014","unstructured":"Silverberg SJ, Clarke BL, Peacock M et al (2014) Current issues in the presentation of asymptomatic primary hyperparathyroidism: proceedings of the fourth international workshop. J Clin Endocrinol Metab 99(10):3580\u20133594","journal-title":"J Clin Endocrinol Metab"},{"issue":"10","key":"5437_CR5","doi-asserted-by":"publisher","first-page":"3561","DOI":"10.1210\/jc.2014-1413","volume":"99","author":"JP Bilezikian","year":"2014","unstructured":"Bilezikian JP, Brandi ML, Eastell R et al (2014) Guidelines for the management of asymptomatic primary hyperparathyroidism: summary statement from the fourth international workshop. J Clin Endocrinol Metab 99(10):3561\u20133569","journal-title":"J Clin Endocrinol Metab"},{"key":"5437_CR6","doi-asserted-by":"publisher","first-page":"1399","DOI":"10.1016\/S0039-6109(05)70236-X","volume":"80","author":"JR Howe","year":"2000","unstructured":"Howe JR (2000) Minimally invasive parathyroid surgery. Surg Clin North Am 80:1399\u20131426","journal-title":"Surg Clin North Am"},{"key":"5437_CR7","doi-asserted-by":"publisher","first-page":"814","DOI":"10.1002\/bjs.5048","volume":"92","author":"P Miccoli","year":"2005","unstructured":"Miccoli P, Barellini L, Monchik JM et al (2005) Randomized clinical trial comparing regional and general anaesthesia in minimally invasive video-assisted parathyroidectomy. Br J Surg. 92:814\u2013818","journal-title":"Br J Surg."},{"key":"5437_CR8","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1097\/01.sla.0000179622.37270.36","volume":"242","author":"H Chen","year":"2005","unstructured":"Chen H, Mack E, Starling JR (2005) A comprehensive evaluation of perioperative adjuncts during minimally invasive parathyroidectomy: which is most reliable? Ann Surg 242:375\u2013383","journal-title":"Ann Surg"},{"issue":"2","key":"5437_CR9","doi-asserted-by":"publisher","first-page":"183","DOI":"10.7863\/jum.2009.28.2.183","volume":"28","author":"ME Tublin","year":"2009","unstructured":"Tublin ME, Pryma DA, Yim JH et al (2009) Localization of parathyroid adenomas by sonography and technetium Tc 99m sestamibi single-photon emission computed tomography before minimally invasive parathyroidectomy: are both studies really needed? J Ultrasound Med 28(2):183\u2013190","journal-title":"J Ultrasound Med"},{"key":"5437_CR10","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1007\/s00268-005-0312-6","volume":"30","author":"M Barczy\u0144ski","year":"2006","unstructured":"Barczy\u0144ski M, Cicho\u0144 S, Konturek A et al (2006) Minimally invasive video-assisted parathyroidectomy versus open minimally invasive parathyroidectomy for a solitary parathyroid adenoma: a prospective, randomized, blinded trial. World J Surg 30:721\u2013731","journal-title":"World J Surg"},{"key":"5437_CR11","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1530\/eje.0.1460783","volume":"146","author":"E Vignali","year":"2002","unstructured":"Vignali E, Picone A, Materazzi G et al (2002) A quick intraoperative parathyroid hormone assay in the surgical management of patients with primary hyperparathyroidism: a study of 206 consecutive cases. Eur J Endocrinol 146:783\u2013788","journal-title":"Eur J Endocrinol"},{"key":"5437_CR12","doi-asserted-by":"publisher","first-page":"1706","DOI":"10.2214\/AJR.06.0938","volume":"188","author":"NA Johnson","year":"2007","unstructured":"Johnson NA, Tublin ME, Ogilvie JB (2007) Parathyroid imaging: technique and role in the preoperative evaluation of primary hyperparathyroidism. AJR 188:1706\u20131715","journal-title":"AJR"},{"key":"5437_CR13","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1053\/j.sult.2011.12.003","volume":"33","author":"CD Phillips","year":"2012","unstructured":"Phillips CD, Shatzkes DR (2012) Imaging of the parathyroid glands. Semin Ultrasound CT MR 33:123\u2013129","journal-title":"Semin Ultrasound CT MR"},{"key":"5437_CR14","doi-asserted-by":"publisher","first-page":"902","DOI":"10.1210\/jc.2012-3168","volume":"98","author":"JW Kunstman","year":"2013","unstructured":"Kunstman JW, Kirsch JD, Mahajan A, Udelsman R (2013) Parathyroid localisation and implications for clinical management. J Clin Endocrinol Metab. 98:902\u2013912","journal-title":"J Clin Endocrinol Metab."},{"key":"5437_CR15","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1007\/s003300101045","volume":"12","author":"C Berczi","year":"2002","unstructured":"Berczi C, Mez\u00f5si E, Galuska L et al (2002) Technetium-99m-sestamibi\/pertechnetate subtraction scintigraphy vs ultrasonography for preoperative localisation in primary hyperparathyroidism. Eur Radiol. 12:605\u2013609","journal-title":"Eur Radiol."},{"key":"5437_CR16","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1530\/eje.0.1430755","volume":"143","author":"F Lumachi","year":"2000","unstructured":"Lumachi F, Zucchetta P, Marzola MC et al (2000) Advantages of combined technetium-99m-sestamibi scintigraphy and high-resolution ultrasonography in parathyroid localisation: comparative study in 91 patients with primary hyperparathyroidism. Eur J Endocrinol 143:755\u2013760","journal-title":"Eur J Endocrinol"},{"key":"5437_CR17","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1148\/radiol.2203000998","volume":"220","author":"A Dalen van","year":"2001","unstructured":"van Dalen A, Smit CP, van Vroonhoven TJ (2001) Minimally invasive surgery for solitary parathyroid adenomas in patients with primary hyperparathyroidism: role of US with supplemental CT. Radiology 220:631\u2013639","journal-title":"Radiology"},{"key":"5437_CR18","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1259\/bjr\/44399050","volume":"77","author":"F Lumachi","year":"2004","unstructured":"Lumachi F, Tregnaghi A, Zucchetta P (2004) Technetium-99m sestamibi scintigraphy and helical CT together in patients with primary hyperparathyroidism: a prospective clinical study. Br J Radiol 77:100\u2013103","journal-title":"Br J Radiol"},{"key":"5437_CR19","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1016\/j.surg.2006.07.028","volume":"140","author":"SE Rodgers","year":"2006","unstructured":"Rodgers SE, Hunter GJ, Hamberg LM et al (2006) Improved preoperative planning for directed parathyroidectomy with 4-dimensional computed tomography. Surgery 140:932\u2013940","journal-title":"Surgery"},{"key":"5437_CR20","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1097\/00004424-200007000-00005","volume":"35","author":"HE Lopez","year":"2000","unstructured":"Lopez HE, Vogl TJ, Steinmuller T, Ricke J, Neuhaus P, Felix R (2000) Preoperative contrast-enhanced MRI of the parathyroid glands in hyperparathyroidism. Invest Radiol 35:426\u2013430","journal-title":"Invest Radiol"},{"key":"5437_CR21","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1148\/radiology.218.3.r01fe38783","volume":"218","author":"MB Gotway","year":"2001","unstructured":"Gotway MB, Reddy GP, Webb WR, Morita ET, Clark OH, Higgins CB (2001) Comparison between MR imaging and 99mTcMIBI scintigraphy in the evaluation of recurrent of persistent hyperparathyroidism. Radiology 218:783\u2013790","journal-title":"Radiology"},{"key":"5437_CR22","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1016\/j.ejrad.2008.03.030","volume":"66","author":"JE Kabala","year":"2008","unstructured":"Kabala JE (2008) Computed tomography and magnetic resonance imaging in diseases of the thyroid and parathyroid. Eur J Radiol 66:480\u2013492","journal-title":"Eur J Radiol"},{"key":"5437_CR23","doi-asserted-by":"publisher","first-page":"1445","DOI":"10.1148\/rg.275065204","volume":"27","author":"MM Barth","year":"2007","unstructured":"Barth MM, Smith MP, Pedrosa I (2007) Body MR imaging at 3.0 T: understanding the opportunities and challenges. Radiographics 27:1445\u20131463","journal-title":"Radiographics"},{"key":"5437_CR24","doi-asserted-by":"publisher","first-page":"981","DOI":"10.1245\/s10434-011-2046-z","volume":"19","author":"AM Grayev","year":"2012","unstructured":"Grayev AM, Gentry LR, Hartman MJ, Chen H, Perlman SB, Reeder SB (2012) Presurgical Localization of parathyroid adenomas with magnetic resonance imaging at 3.0 T: an adjunct method to supplement traditional imaging. Ann Surg Oncol 19:981\u2013989","journal-title":"Ann Surg Oncol"},{"key":"5437_CR25","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1007\/s00330-015-3854-5","volume":"26","author":"B Sacconi","year":"2015","unstructured":"Sacconi B, Argir\u00f2 R, Diacinti D et al (2015) MR appearance of parathyroid adenomas at 3 T in patients with primary hyperparathyroidism: what radiologists need to know for pre-operative localisation. Eur Radiol 26:664\u2013673","journal-title":"Eur Radiol"},{"key":"5437_CR26","doi-asserted-by":"publisher","first-page":"1868","DOI":"10.2214\/ajr.184.6.01841868","volume":"184","author":"GM Israel","year":"2005","unstructured":"Israel GM, Hindman N, Hecht E et al (2005) The use of opposed-phase chemical shift MRI in the diagnosis of renal angiomyolipomas. AJR 184:1868\u20131872","journal-title":"AJR"},{"key":"5437_CR27","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1148\/radiol.2015142393","volume":"277","author":"M Bahl","year":"2015","unstructured":"Bahl M, Sepahdari AR, Sosa JA, Hoang JK (2015) Parathyroid adenomas and hyperplasia on four-dimensional CT scans: three patterns of enhancement relative to the thyroid gland justify a three-phase protocol. Radiology 277:454\u2013462","journal-title":"Radiology"},{"key":"5437_CR28","doi-asserted-by":"publisher","first-page":"429","DOI":"10.3174\/ajnr.A2805","volume":"33","author":"JL Chazen","year":"2012","unstructured":"Chazen JL, Gupta A, Dunning A, Phillips CD (2012) Diagnostic accuracy of 4D-CT for parathyroid adenomas and hyperplasia. AJNR 33:429\u2013433","journal-title":"AJNR"},{"key":"5437_CR29","doi-asserted-by":"publisher","first-page":"2323","DOI":"10.3174\/ajnr.A4948","volume":"37","author":"S Sho","year":"2016","unstructured":"Sho S, Yilma M, Yeh MW et al (2016) Prospective validation of two 4D-CT-based scoring systems for prediction of multigland disease in primary hyperparathyroidism. AJNR 37:2323\u20132327","journal-title":"AJNR"},{"key":"5437_CR30","doi-asserted-by":"publisher","first-page":"2373","DOI":"10.3174\/ajnr.A4473","volume":"36","author":"B Griffith","year":"2015","unstructured":"Griffith B, Chaudhary H, Mahmood G et al (2015) Accuracy of 2-phase parathyroid CT for the preoperative localization of parathyroid adenomas in primary hyperparathyroidism. AJNR 36:2373\u20132379","journal-title":"AJNR"},{"key":"5437_CR31","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.ejrad.2017.01.004","volume":"88","author":"WP Kluijfhout","year":"2017","unstructured":"Kluijfhout WP, Pasternak JD, Beninato T et al (2017) Diagnostic performance of computed tomography for parathyroid adenoma localisation; a systematic review and meta-analysis. Eur J Radiol. 88:117\u2013128","journal-title":"Eur J Radiol."},{"key":"5437_CR32","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1053\/j.semnuclmed.2005.06.001","volume":"35","author":"CJ Palestro","year":"2005","unstructured":"Palestro CJ, Tomas MB, Tronco GG (2005) Radionuclide imaging of the parathyroid glands. Semin Nucl Med 35:266\u2013276","journal-title":"Semin Nucl Med"},{"issue":"1","key":"5437_CR33","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s40477-014-0067-8","volume":"17","author":"GM Vitetta","year":"2014","unstructured":"Vitetta GM, Neri P, Chiecchio A (2014) Role of ultrasonography in the management of patients with primary hyperparathyroidism: retrospective comparison with technetium-99m sestamibi scintigraphy. J Ultrasound 17(1):1\u201312","journal-title":"J Ultrasound"},{"key":"5437_CR34","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1097\/01.MLG.0000203411.53666.AD","volume":"116","author":"Y Erbil","year":"2006","unstructured":"Erbil Y, Barbaros U, Yanik BT et al (2006) Impact of gland morphology and concomitant thyroid nodules on preoperative localisation of parathyroid adenomas. Laryngoscope 116:580\u2013585","journal-title":"Laryngoscope"},{"key":"5437_CR35","doi-asserted-by":"publisher","first-page":"1303","DOI":"10.1016\/j.surg.2004.06.062","volume":"136","author":"SL Sugg","year":"2004","unstructured":"Sugg SL, Krzywda EA, Demeure MJ et al (2004) Detection of multiple gland primary hyperparathyroidism in the era of minimally invasive parathyroidectomy. Surgery 136:1303\u20131309","journal-title":"Surgery"},{"key":"5437_CR36","doi-asserted-by":"publisher","first-page":"1745","DOI":"10.1016\/j.ejrad.2015.05.024","volume":"84","author":"WP Kluijfhout","year":"2015","unstructured":"Kluijfhout WP, Vorselaars WM, Vriens MR, Borel Rinkes IH, Valk GD, de Keizer B (2015) Enabling minimal invasive parathyroidectomy for patients with primary hyperparathyroidism using Tc-99m-sestamibi SPECT-CT, ultrasound and first results of (18)F-fluorocholine PET-CT. Eur J Radiol 84:1745\u20131751","journal-title":"Eur J Radiol"},{"issue":"41","key":"5437_CR37","doi-asserted-by":"publisher","first-page":"e1701","DOI":"10.1097\/MD.0000000000001701","volume":"94","author":"L Michaud","year":"2015","unstructured":"Michaud L, Balogova S, Burgess A et al (2015) A pilot comparison of 18F-fluorocholine PET\/CT, ultrasonography and 123I\/99mTc-sestaMIBI dual-phase dual-isotope scintigraphy in the preoperative localization of hyperfunctioning parathyroid glands in primary or secondary hyperparathyroidism: influence of thyroid anomalies. Medicine 94(41):e1701","journal-title":"Medicine"},{"issue":"6","key":"5437_CR38","doi-asserted-by":"publisher","first-page":"2700","DOI":"10.1007\/s00330-017-5190-4","volume":"28","author":"G. F. Huber","year":"2018","unstructured":"Huber GF, H\u00fcllner M, Schmid C et al (2018) Benefit of 18F-fluorocholine PET imaging in parathyroid surgery. Eur Radiol. https:\/\/doi.org\/10.1007\/s00330-017-5190-4","journal-title":"European Radiology"},{"issue":"3","key":"5437_CR39","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1148\/92.3.527","volume":"92","author":"JL Doppman","year":"1969","unstructured":"Doppman JL, Hammond WG, Melson GL et al (1969) Staining of parathyroid adenomas by selective arteriography. Radiology 92(3):527\u2013530","journal-title":"Radiology"},{"key":"5437_CR40","doi-asserted-by":"publisher","first-page":"2147","DOI":"10.3174\/ajnr.A4425","volume":"36","author":"K Nael","year":"2015","unstructured":"Nael K, Hur J, Bauer A et al (2015) Dynamic 4D MRI for characterization of parathyroid adenomas: multiparametric analysis. AJNR 36:2147\u20132152","journal-title":"AJNR"},{"key":"5437_CR41","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1016\/j.suc.2014.02.006","volume":"94","author":"CC Solorzano","year":"2014","unstructured":"Solorzano CC, Carneiro-Pla D (2014) Minimizing cost and maximizing success in the preoperative localisation strategy for primary hyperparathyroidism. Surg Clin North Am. 94:587\u2013605","journal-title":"Surg Clin North Am."},{"key":"5437_CR42","doi-asserted-by":"publisher","first-page":"4202","DOI":"10.1245\/s10434-012-2512-2","volume":"19","author":"CC Lubitz","year":"2012","unstructured":"Lubitz CC, Stephen AE, Hodin RA, Pandharipande P (2012) Preoperative localisation strategies for primary hyperparathyroidism: an economic analysis. Ann Surg Oncol 19:4202\u20134209","journal-title":"Ann Surg Oncol"}],"container-title":["European Radiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00330-018-5437-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-018-5437-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-018-5437-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,22]],"date-time":"2022-08-22T14:44:28Z","timestamp":1661179468000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00330-018-5437-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,7]]},"references-count":42,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["5437"],"URL":"https:\/\/doi.org\/10.1007\/s00330-018-5437-8","relation":{},"ISSN":["0938-7994","1432-1084"],"issn-type":[{"value":"0938-7994","type":"print"},{"value":"1432-1084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,7]]},"assertion":[{"value":"20 December 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 March 2018","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 March 2018","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 May 2018","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The scientific guarantor of this publication is Prof. Carlo Catalano","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Guarantor"}},{"value":"The authors of this manuscript declare no relationships with any companies whose products or services may be related to the subject matter of the article.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"No complex statistical methods were necessary for this paper.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statistics and biometry"}},{"value":"Institutional Review Board approval was obtained","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Written informed consent was obtained from all subjects (patients) in this study.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"\u2022 prospective\u2022 observational study\u2022 performed at one institution","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Methodology"}}]}}