{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T16:49:46Z","timestamp":1793292586348,"version":"4.5.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2018,7,27]],"date-time":"2018-07-27T00:00:00Z","timestamp":1532649600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Radiol"],"published-print":{"date-parts":[[2019,2]]},"DOI":"10.1007\/s00330-018-5647-0","type":"journal-article","created":{"date-parts":[[2018,7,27]],"date-time":"2018-07-27T07:21:02Z","timestamp":1532676062000},"page":"663-673","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":79,"title":["Intracardiac cement embolism during percutaneous vertebroplasty: incidence, risk factors and clinical management"],"prefix":"10.1007","volume":"29","author":[{"given":"Sarah","family":"Fadili Hassani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyne","family":"Cormier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eimad","family":"Shotar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Drir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Philippe","family":"Spano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laetitia","family":"Morardet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Philippe","family":"Collet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Chiras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Claren\u00e7on","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,7,27]]},"reference":[{"key":"5647_CR1","first-page":"570","volume":"28","author":"V Calmels","year":"2007","unstructured":"Calmels V, Vall\u00e9e J-N, Rose M, Chiras J (2007) Osteoblastic and mixed spinal metastases: evaluation of the analgesic efficacy of percutaneous vertebroplasty. AJNR Am J Neuroradiol 28:570\u2013574","journal-title":"AJNR Am J Neuroradiol"},{"key":"5647_CR2","doi-asserted-by":"publisher","first-page":"4083","DOI":"10.1016\/j.ejrad.2012.07.005","volume":"81","author":"GC Anselmetti","year":"2012","unstructured":"Anselmetti GC, Marcia S, Saba L et al (2012) Percutaneous vertebroplasty: multi-centric results from EVEREST experience in large cohort of patients. Eur J Radiol 81:4083\u20134086. \n                    https:\/\/doi.org\/10.1016\/j.ejrad.2012.07.005","journal-title":"Eur J Radiol"},{"key":"5647_CR3","doi-asserted-by":"publisher","first-page":"2352","DOI":"10.1007\/s00330-015-4035-2","volume":"26","author":"F Claren\u00e7on","year":"2016","unstructured":"Claren\u00e7on F, Fahed R, Gabrieli J et al (2016) Safety and clinical effectiveness of percutaneous vertebroplasty in the elderly (\u226580 years). Eur Radiol 26:2352\u20132358. \n                    https:\/\/doi.org\/10.1007\/s00330-015-4035-2","journal-title":"Eur Radiol"},{"key":"5647_CR4","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1148\/radiol.2381040841","volume":"238","author":"HM Barrag\u00e1n-Campos","year":"2006","unstructured":"Barrag\u00e1n-Campos HM, Vall\u00e9e J-N, Lo D et al (2006) Percutaneous vertebroplasty for spinal metastases: complications. Radiology 238:354\u2013362. \n                    https:\/\/doi.org\/10.1148\/radiol.2381040841","journal-title":"Radiology"},{"key":"5647_CR5","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1007\/s00330-008-1133-4","volume":"19","author":"S Masala","year":"2009","unstructured":"Masala S, Mastrangeli R, Petrella MC et al (2009) Percutaneous vertebroplasty in 1,253 levels: results and long-term effectiveness in a single centre. Eur Radiol 19:165\u2013171. \n                    https:\/\/doi.org\/10.1007\/s00330-008-1133-4","journal-title":"Eur Radiol"},{"key":"5647_CR6","first-page":"1697","volume":"24","author":"JM Mathis","year":"2003","unstructured":"Mathis JM (2003) Percutaneous vertebroplasty: complication avoidance and technique optimization. AJNR Am J Neuroradiol 24:1697\u20131706","journal-title":"AJNR Am J Neuroradiol"},{"key":"5647_CR7","doi-asserted-by":"publisher","first-page":"E379","DOI":"10.1097\/01.brs.0000219495.57470.67","volume":"31","author":"Y-J Chen","year":"2006","unstructured":"Chen Y-J, Tan T-S, Chen W-H et al (2006) Intradural cement leakage: a devastatingly rare complication of vertebroplasty. Spine 31:E379\u2013E382. \n                    https:\/\/doi.org\/10.1097\/01.brs.0000219495.57470.67","journal-title":"Spine"},{"key":"5647_CR8","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1016\/j.neuchi.2008.02.063","volume":"54","author":"M Gaye","year":"2008","unstructured":"Gaye M, Fuentes S, Pech-Gourg G et al (2008) Spondylodiscite post-vert\u00e9broplastie. Cas clinique et revue de la litt\u00e9rature. Neurochirurgie 54:551\u2013555. \n                    https:\/\/doi.org\/10.1016\/j.neuchi.2008.02.063","journal-title":"Neurochirurgie"},{"key":"5647_CR9","doi-asserted-by":"publisher","unstructured":"Laredo JD, Hamze B (2004) Complications of percutaneous vertebroplasty and their prevention. Skeletal Radiol 33. doi: \n                    https:\/\/doi.org\/10.1007\/s00256-004-0776-8","DOI":"10.1007\/s00256-004-0776-8"},{"key":"5647_CR10","doi-asserted-by":"crossref","unstructured":"Groen RJM, du Toit DF, Phillips FM et al (2004) Anatomical and pathological considerations in percutaneous vertebroplasty and kyphoplasty: a reappraisal of the vertebral venous system. Spine (Phila Pa 1976) 29:1465\u20131471","DOI":"10.1097\/01.BRS.0000128758.64381.75"},{"key":"5647_CR11","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1007\/s00586-004-0839-5","volume":"14","author":"R Schmidt","year":"2005","unstructured":"Schmidt R, Cakir B, Mattes T et al (2005) Cement leakage during vertebroplasty: an underestimated problem? Eur Spine J 14:466\u2013473. \n                    https:\/\/doi.org\/10.1007\/s00586-004-0839-5","journal-title":"Eur Spine J"},{"key":"5647_CR12","doi-asserted-by":"publisher","unstructured":"Geraci G, Lo Iacono G, Lo Nigro C, Cannizzaro F, Cajozzo M, Modica G (2013) Asymptomatic bone cement pulmonary embolism after vertebroplasty: case report and literature review. Case Rep Surg 2013, 2013:591432. \n                    https:\/\/doi.org\/10.1155\/2013\/591432","DOI":"10.1155\/2013\/591432"},{"key":"5647_CR13","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.3174\/ajnr.A2127","volume":"31","author":"A Venmans","year":"2010","unstructured":"Venmans A, Klazen CAH, Lohle PNM et al (2010) Percutaneous vertebroplasty and pulmonary cement embolism: results from VERTOS II. AJNR Am J Neuroradiol 31:1451\u20131453. \n                    https:\/\/doi.org\/10.3174\/ajnr.A2127","journal-title":"AJNR Am J Neuroradiol"},{"key":"5647_CR14","doi-asserted-by":"publisher","first-page":"654","DOI":"10.3174\/ajnr.A2368","volume":"32","author":"MT Luetmer","year":"2011","unstructured":"Luetmer MT, Bartholmai BJ, Rad AE, Kallmes DF (2011) Asymptomatic and unrecognized cement pulmonary embolism commonly occurs with vertebroplasty. AJNR Am J Neuroradiol 32:654\u2013657. \n                    https:\/\/doi.org\/10.3174\/ajnr.A2368","journal-title":"AJNR Am J Neuroradiol"},{"key":"5647_CR15","doi-asserted-by":"publisher","first-page":"1983","DOI":"10.3174\/ajnr.A1269","volume":"29","author":"A Venmans","year":"2008","unstructured":"Venmans A, Lohle PNM, van Rooij WJ et al (2008) Frequency and outcome of pulmonary polymethylmethacrylate embolism during percutaneous vertebroplasty. AJNR Am J Neuroradiol 29:1983\u20131985. \n                    https:\/\/doi.org\/10.3174\/ajnr.A1269","journal-title":"AJNR Am J Neuroradiol"},{"key":"5647_CR16","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1148\/radiol.2511080854","volume":"251","author":"YJ Kim","year":"2009","unstructured":"Kim YJ, Lee JW, Park KW et al (2009) Pulmonary cement embolism after percutaneous vertebroplasty in osteoporotic vertebral compression fractures: incidence, characteristics, and risk factors. Radiology 251:250\u2013259. \n                    https:\/\/doi.org\/10.1148\/radiol.2511080854","journal-title":"Radiology"},{"key":"5647_CR17","doi-asserted-by":"publisher","unstructured":"Kim SY, Seo JB, Do K-H et al (2005) Cardiac perforation caused by acrylic cement: a rare complication of percutaneous vertebroplasty. AJR Am J Roentgenol 185:1245\u20131247. \n                    https:\/\/doi.org\/10.2214\/AJR.04.1443","DOI":"10.2214\/AJR.04.1443"},{"key":"5647_CR18","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1093\/eurheartj\/ehu300","volume":"36","author":"S Schuerer","year":"2015","unstructured":"Schuerer S, Misfeld M, Schuler G, Mangner N (2015) Intracardiac cement embolization in a 65-year-old man four months after multilevel spine fusion. Eur Heart J 36:783. \n                    https:\/\/doi.org\/10.1093\/eurheartj\/ehu300","journal-title":"Eur Heart J"},{"key":"5647_CR19","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1016\/j.athoracsur.2010.06.106","volume":"91","author":"A Dash","year":"2011","unstructured":"Dash A, Brinster DR (2011) Open heart surgery for removal of polymethylmethacrylate after percutaneous vertebroplasty. Ann Thorac Surg 91:276\u2013278. \n                    https:\/\/doi.org\/10.1016\/j.athoracsur.2010.06.106","journal-title":"Ann Thorac Surg"},{"key":"5647_CR20","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1007\/s00392-013-0542-9","volume":"102","author":"RA Llanos","year":"2013","unstructured":"Llanos RA, Viana-Tejedor A, Abella HR, Fernandez-Avil\u00e9s F (2013) Pulmonary and intracardiac cement embolism after a percutaneous vertebroplasty. Clin Res Cardiol 102:395\u2013397. \n                    https:\/\/doi.org\/10.1007\/s00392-013-0542-9","journal-title":"Clin Res Cardiol"},{"key":"5647_CR21","doi-asserted-by":"publisher","unstructured":"Hatzantonis C, Czyz M, Pyzik R, Boszczyk BM (2016) Intracardiac bone cement embolism as a complication of vertebroplasty: management strategy. Eur Spine J. \n                    https:\/\/doi.org\/10.1007\/s00586-016-4695-x","DOI":"10.1007\/s00586-016-4695-x"},{"key":"5647_CR22","doi-asserted-by":"publisher","first-page":"326","DOI":"10.12659\/AJCR.897719","volume":"17","author":"ZA Audat","year":"2016","unstructured":"Audat ZA, Alfawareh MD, Darwish FT, Alomari AA (2016) Intracardiac leakage of cement during kyphoplasty and vertebroplasty: a case report. Am J Case Rep 17:326\u2013330","journal-title":"Am J Case Rep"},{"key":"5647_CR23","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1016\/j.jvir.2011.12.027","volume":"23","author":"T Mattis","year":"2012","unstructured":"Mattis T, Knox M, Mammen L (2012) Intracardiac methylmethacrylate embolism resulting in right atrial wall perforation and pericarditis following percutaneous vertebroplasty. J Vasc Interv Radiol 23:719\u2013720. \n                    https:\/\/doi.org\/10.1016\/j.jvir.2011.12.027","journal-title":"J Vasc Interv Radiol"},{"key":"5647_CR24","doi-asserted-by":"publisher","unstructured":"Shridhar P, Chen Y, Khalil R et al (2016) A review of PMMA bone cement and intra-cardiac embolism. Materials (Basel) 9:821. \n                    https:\/\/doi.org\/10.3390\/ma9100821","DOI":"10.3390\/ma9100821"},{"key":"5647_CR25","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1160\/TH06-03-0158","volume":"95","author":"M Righini","year":"2006","unstructured":"Righini M, Sekoranja L, Le Gal G et al (2006) Pulmonary cement embolism after vertebroplasty. Thromb Haemost 95:388\u2013389","journal-title":"Thromb Haemost"},{"key":"5647_CR26","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.1007\/s00586-009-1073-y","volume":"18","author":"A Krueger","year":"2009","unstructured":"Krueger A, Bliemel C, Zettl R, Ruchholtz S (2009) Management of pulmonary cement embolism after percutaneous vertebroplasty and kyphoplasty: a systematic review of the literature. Eur Spine J 18:1257\u20131265. \n                    https:\/\/doi.org\/10.1007\/s00586-009-1073-y","journal-title":"Eur Spine J"},{"key":"5647_CR27","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1016\/j.spinee.2011.07.027","volume":"11","author":"MJ Nieuwenhuijse","year":"2011","unstructured":"Nieuwenhuijse MJ, Van Erkel AR, Dijkstra PDS (2011) Cement leakage in percutaneous vertebroplasty for osteoporotic vertebral compression fractures: identification of risk factors. Spine J 11:839\u2013848. \n                    https:\/\/doi.org\/10.1016\/j.spinee.2011.07.027","journal-title":"Spine J"},{"key":"5647_CR28","doi-asserted-by":"publisher","unstructured":"Loeffel M, Ferguson SJ, Nolte L-P, Kowal JH (2008) Vertebroplasty: experimental characterization of polymethylmethacrylate bone cement spreading as a function of viscosity, bone porosity, and flow rate. Spine (Phila Pa 1976) 33:1352\u20131359. \n                    https:\/\/doi.org\/10.1097\/BRS.0b013e3181732aa9","DOI":"10.1097\/BRS.0b013e3181732aa9"},{"key":"5647_CR29","doi-asserted-by":"publisher","first-page":"2721","DOI":"10.1016\/S0142-9612(03)00086-3","volume":"24","author":"M Bohner","year":"2003","unstructured":"Bohner M, Gasser B, Baroud G, Heini P (2003) Theoretical and experimental model to describe the injection of a polymethylmethacrylate cement into a porous structure. Biomaterials 24:2721\u20132730","journal-title":"Biomaterials"},{"key":"5647_CR30","doi-asserted-by":"publisher","unstructured":"Baroud G, Crookshank M, Bohner M (2006) High-viscosity cement significantly enhances uniformity of cement filling in vertebroplasty: an experimental model and study on cement leakage. Spine (Phila Pa 1976) 31:2562\u20132568. \n                    https:\/\/doi.org\/10.1097\/01.brs.0000240695.58651.62","DOI":"10.1097\/01.brs.0000240695.58651.62"},{"key":"5647_CR31","doi-asserted-by":"publisher","first-page":"2249","DOI":"10.1007\/s00586-013-2886-2","volume":"22","author":"B Meng","year":"2013","unstructured":"Meng B, Qian M, Xia S-X et al (2013) Biomechanical characteristics of cement\/gelatin mixture for prevention of cement leakage in vertebral augmentation. Eur Spine J 22:2249\u20132255. \n                    https:\/\/doi.org\/10.1007\/s00586-013-2886-2","journal-title":"Eur Spine J"},{"key":"5647_CR32","doi-asserted-by":"publisher","unstructured":"Potet J, Weber-Donat G, Curis E et al (2013) Incidence of pulmonary cement embolism after real-time CT fluoroscopy-guided vertebroplasty. J Vasc Interv Radiol 24:1853\u20131860. \n                    https:\/\/doi.org\/10.1016\/j.jvir.2013.05.048","DOI":"10.1016\/j.jvir.2013.05.048"}],"container-title":["European Radiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00330-018-5647-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-018-5647-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-018-5647-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,26]],"date-time":"2019-07-26T23:07:35Z","timestamp":1564182455000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00330-018-5647-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,27]]},"references-count":32,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["5647"],"URL":"https:\/\/doi.org\/10.1007\/s00330-018-5647-0","relation":{},"ISSN":["0938-7994","1432-1084"],"issn-type":[{"value":"0938-7994","type":"print"},{"value":"1432-1084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,27]]},"assertion":[{"value":"5 March 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 June 2018","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 July 2018","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 July 2018","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The scientific guarantor of this publication is Prof. Fr\u00e9d\u00e9ric Claren\u00e7on.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Guarantor"}},{"value":"The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"No complex statistical methods were necessary for this paper.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statistics and biometry"}},{"value":"Written informed consent was waived by the Institutional Review Board.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"Institutional Review Board approval was not required because French law states that no approval from a local IRB is necessary for retrospective analysis of patients' charts.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"\u2022 retrospective\u2022 observational\u2022 performed at one institution","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Methodology"}}]}}