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JL has given an educational presentation for Merck and Sanofi that paid to his institution.Research programs of WF have been funded by ZonMW, NWO, EU-FP7, Alzheimer Nederland, CardioVascular Onderzoek Nederland, stichting Dioraphte, Gieskes-Strijbis fonds, Boehringer Ingelheim, Piramal Neuroimaging, Roche BV, Janssen Stellar, and Combinostics. WF has performed contract research for Boehringer Ingelheim. WF has been an invited speaker at Boehringer Ingelheim. All funding is paid to her institution.PS has acquired grant support (for the institution) from GE Healthcare, Danone Research, Piramal, and MERCK. In the past 2\u00a0years, he has received consultancy\/speaker fees (paid to the institution) from Lilly, GE Healthcare, Novartis, Probiodrug, Biogen, Roche, and EIP Pharma.FB has consultancy payments from Biogen-Idec, TEVA, Merck-Serono, Novartis, Roche, Jansen Research, Genzyme-Sanofi, IXICO Ltd., GeNeuro, and Apitope Ltd. and payments for development of educational presentations from Biogen-IDEC and IXICO Ltd.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"One of the authors has significant statistical expertise (MvG).","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statistics and biometry"}},{"value":"Written informed consent was obtained from all subjects (patients) in this study.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"Institutional Review Board approval was obtained.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Some study subjects or cohorts have been previously reported in the following:Amsterdam Dementia Cohort (ADC): van der Flier WM, Pijnenburg YAL, Prins N, et al (2014) Optimizing patient care and research: the Amsterdam Dementia Cohort. <i>J Alzheimers Dis<\/i>. 41:313\u2013327Cohort from the PredictND EU FP7 project (PredictND): Bruun M, Gjerum L, Frederiksen K, et al (2017) Data-driven diagnosis of dementia disorders: the PredictND validation study. <i>Alzheimer\u2019s & Dementia<\/i> 13(7):405\u2013407 (Supplement)Alzheimer\u2019s Disease Neuroimaging Initiative (ADNI): Petersen RC, Aisen P, Beckett L, et al (2010) Alzheimer\u2019s Disease Neuroimaging Initiative (ADNI). <i>Neurology<\/i> 74(3):201\u2013209","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Study subjects or cohorts overlap"}},{"value":"\u2022 retrospective\u2022 cross-sectional study\u2022 multicenter study","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Methodology"}}]}}