{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T18:04:30Z","timestamp":1793210670853,"version":"4.5.0"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2019,10,30]],"date-time":"2019-10-30T00:00:00Z","timestamp":1572393600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,10,30]],"date-time":"2019-10-30T00:00:00Z","timestamp":1572393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81571664"],"award-info":[{"award-number":["81571664"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81871323"],"award-info":[{"award-number":["81871323"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81801665"],"award-info":[{"award-number":["81801665"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81227901"],"award-info":[{"award-number":["81227901"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81771924"],"award-info":[{"award-number":["81771924"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81501616"],"award-info":[{"award-number":["81501616"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81671854"],"award-info":[{"award-number":["81671854"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"crossref","award":["2018B030311024"],"award-info":[{"award-number":["2018B030311024"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Scientific Research General Project of Guangzhou Science Technology and Innovation Commission","award":["201707010328"],"award-info":[{"award-number":["201707010328"]}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2016M600145"],"award-info":[{"award-number":["2016M600145"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004826","name":"Beijing Natural Science Foundation","doi-asserted-by":"crossref","award":["L182061"],"award-info":[{"award-number":["L182061"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Radiol"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1007\/s00330-019-06452-w","type":"journal-article","created":{"date-parts":[[2019,10,31]],"date-time":"2019-10-31T11:04:33Z","timestamp":1572519873000},"page":"833-843","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Prognostic value of the radiomics-based model in progression-free survival of hypopharyngeal cancer treated with chemoradiation"],"prefix":"10.1007","volume":"30","author":[{"given":"Xiaokai","family":"Mo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangjun","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Di","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baoliang","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changhong","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoning","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhao","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhouyang","family":"Lian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shufang","family":"Pei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenhui","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fusheng","family":"Ouyang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7377-382X","authenticated-orcid":false,"given":"Shuixing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,10,30]]},"reference":[{"key":"6452_CR1","unstructured":"American Cancer Society (2018) Cancer Facts and Figures 2018. \nhttps:\/\/www.cancer.org\/cancer-facts-and-figures-2018.pdf.\n\n Accessed August 1, 2018."},{"key":"6452_CR2","doi-asserted-by":"publisher","first-page":"2064","DOI":"10.1002\/lary.24651","volume":"124","author":"P Kuo","year":"2014","unstructured":"Kuo P, Chen MM, Decker RH, Yarbrough WG, Judson BL (2014) Hypopharyngeal cancer incidence, treatment, and survival: Temporal trends in the United States. Laryngoscope 124:2064\u20132069","journal-title":"Laryngoscope"},{"key":"6452_CR3","unstructured":"American Cancer Society (2017) Cancer Facts and Figures 2017. \nhttps:\/\/www.cancer.org\/cancer-facts-and-figures-2017.pdf.\n\n Accessed August 1, 2018."},{"key":"6452_CR4","doi-asserted-by":"publisher","first-page":"798","DOI":"10.1053\/j.seminoncol.2014.09.018","volume":"41","author":"V Bar-Ad","year":"2014","unstructured":"Bar-Ad V, Palmer J, Yang H et al (2014) Current management of locally advanced head and neck cancer: the combination of chemotherapy with locoregional treatments. Semin Oncol 41:798\u2013806","journal-title":"Semin Oncol"},{"key":"6452_CR5","doi-asserted-by":"publisher","first-page":"1853","DOI":"10.1002\/cncr.29962","volume":"122","author":"P Kuo","year":"2016","unstructured":"Kuo P, Sosa JA, Burtness BA et al (2016) Treatment trends and survival effects of chemotherapy for hypopharyngeal cancer: Analysis of the National Cancer Data Base. Cancer 122:1853\u20131860","journal-title":"Cancer"},{"key":"6452_CR6","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1002\/hed.21613","volume":"34","author":"RP Takes","year":"2012","unstructured":"Takes RP, Strojan P, Silver CE et al (2012) Current trends in initial management of hypopharyngeal cancer: the declining use of open surgery. Head Neck 34:270\u2013281","journal-title":"Head Neck"},{"key":"6452_CR7","doi-asserted-by":"crossref","unstructured":"Hamoir M, Schmitz S, Suarez C et al (2018) The Current Role of Salvage Surgery in Recurrent Head and Neck Squamous Cell Carcinoma. Cancers (Basel) 10","DOI":"10.3390\/cancers10080267"},{"key":"6452_CR8","doi-asserted-by":"publisher","first-page":"625","DOI":"10.3109\/0284186X.2015.1117136","volume":"55","author":"A Pagh","year":"2016","unstructured":"Pagh A, Grau C, Overgaard J (2016) Failure pattern and salvage treatment after radical treatment of head and neck cancer. Acta Oncol 55:625\u2013632","journal-title":"Acta Oncol"},{"key":"6452_CR9","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1177\/0194599814535183","volume":"151","author":"K Matoscevic","year":"2014","unstructured":"Matoscevic K, Graf N, Pezier TF, Huber GF (2014) Success of salvage treatment: a critical appraisal of salvage rates for different subsites of HNSCC. Otolaryngol Head Neck Surg 151:454\u2013461","journal-title":"Otolaryngol Head Neck Surg"},{"key":"6452_CR10","doi-asserted-by":"publisher","first-page":"2844","DOI":"10.1200\/JCO.2013.50.3136","volume":"31","author":"AA Forastiere","year":"2013","unstructured":"Forastiere AA, Adelstein DJ, Manola J (2013) Induction chemotherapy meta-analysis in head and neck cancer: right answer, wrong question. J Clin Oncol 31:2844\u20132846","journal-title":"J Clin Oncol"},{"key":"6452_CR11","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.ijrobp.2013.12.027","volume":"89","author":"JJ Beitler","year":"2014","unstructured":"Beitler JJ, Zhang Q, Fu KK et al (2014) Final results of local-regional control and late toxicity of RTOG 9003: a randomized trial of altered fractionation radiation for locally advanced head and neck cancer. Int J Radiat Oncol Biol Phys 89:13\u201320","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"6452_CR12","doi-asserted-by":"publisher","first-page":"4162","DOI":"10.1007\/s00330-016-4276-8","volume":"26","author":"SH Ng","year":"2016","unstructured":"Ng SH, Liao CT, Lin CY et al (2016) Dynamic contrast-enhanced MRI, diffusion-weighted MRI and (18)F-FDG PET\/CT for the prediction of survival in oropharyngeal or hypopharyngeal squamous cell carcinoma treated with chemoradiation. Eur Radiol 26:4162\u20134172","journal-title":"Eur Radiol"},{"key":"6452_CR13","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1097\/RLU.0000000000000613","volume":"40","author":"K Pak","year":"2015","unstructured":"Pak K, Cheon GJ, Kang KW, Chung JK, Kim EE, Lee DS (2015) Prognostic value of SUVmean in oropharyngeal and hypopharyngeal cancers: comparison with SUVmax and other volumetric parameters of 18F-FDG PET. Clin Nucl Med 40:9\u201313","journal-title":"Clin Nucl Med"},{"key":"6452_CR14","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1148\/radiol.2015151169","volume":"278","author":"RJ Gillies","year":"2016","unstructured":"Gillies RJ, Kinahan PE, Hricak H (2016) Radiomics: images are more than pictures, they are data. Radiology 278:563\u2013577","journal-title":"Radiology"},{"key":"6452_CR15","doi-asserted-by":"publisher","first-page":"5150","DOI":"10.1038\/s41467-018-07582-3","volume":"9","author":"M Bartoschek","year":"2018","unstructured":"Bartoschek M, Oskolkov N, Bocci M et al (2018) Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing. Nat Commun 9:5150","journal-title":"Nat Commun"},{"key":"6452_CR16","doi-asserted-by":"publisher","first-page":"11044","DOI":"10.1038\/srep11044","volume":"5","author":"C Parmar","year":"2015","unstructured":"Parmar C, Leijenaar RT, Grossmann P et al (2015) Radiomic feature clusters and prognostic signatures specific for Lung and Head & Neck cancer. Sci Rep 5:11044","journal-title":"Sci Rep"},{"key":"6452_CR17","doi-asserted-by":"publisher","first-page":"4259","DOI":"10.1158\/1078-0432.CCR-16-2910","volume":"23","author":"B Zhang","year":"2017","unstructured":"Zhang B, Tian J, Dong D et al (2017) Radiomics Features of Multiparametric MRI as Novel Prognostic Factors in Advanced Nasopharyngeal Carcinoma. Clin Cancer Res 23:4259\u20134269","journal-title":"Clin Cancer Res"},{"key":"6452_CR18","doi-asserted-by":"publisher","first-page":"3503","DOI":"10.1200\/JCO.2011.35.7301","volume":"29","author":"BS Rose","year":"2011","unstructured":"Rose BS, Jeong JH, Nath SK, Lu SM, Mell LK (2011) Population-based study of competing mortality in head and neck cancer. J Clin Oncol 29:3503\u20133509","journal-title":"J Clin Oncol"},{"key":"6452_CR19","doi-asserted-by":"publisher","first-page":"13206","DOI":"10.1038\/s41598-017-13448-3","volume":"7","author":"S Leger","year":"2017","unstructured":"Leger S, Zwanenburg A, Pilz K et al (2017) A comparative study of machine learning methods for time-to-event survival data for radiomics risk modelling. Sci Rep 7:13206","journal-title":"Sci Rep"},{"key":"6452_CR20","doi-asserted-by":"publisher","first-page":"1531","DOI":"10.1080\/0284186X.2017.1346382","volume":"56","author":"M Bogowicz","year":"2017","unstructured":"Bogowicz M, Riesterer O, Stark LS et al (2017) Comparison of PET and CT radiomics for prediction of local tumor control in head and neck squamous cell carcinoma. Acta Oncol 56:1531\u20131536","journal-title":"Acta Oncol"},{"key":"6452_CR21","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1186\/1471-2288-13-33","volume":"13","author":"P Royston","year":"2013","unstructured":"Royston P, Altman DG (2013) External validation of a Cox prognostic model: principles and methods. BMC Med Res Methodol 13:33","journal-title":"BMC Med Res Methodol"},{"key":"6452_CR22","doi-asserted-by":"publisher","first-page":"1471","DOI":"10.1245\/s10434-010-0985-4","volume":"17","author":"SB Edge","year":"2010","unstructured":"Edge SB, Compton CC (2010) The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM. Ann Surg Oncol 17:1471\u20131474","journal-title":"Ann Surg Oncol"},{"key":"6452_CR23","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1016\/j.ejca.2011.11.036","volume":"48","author":"P Lambin","year":"2012","unstructured":"Lambin P, Rios-Velazquez E, Leijenaar R et al (2012) Radiomics: extracting more information from medical images using advanced feature analysis. Eur J Cancer 48:441\u2013446","journal-title":"Eur J Cancer"},{"key":"6452_CR24","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1007\/s00259-016-3580-5","volume":"44","author":"SW Chen","year":"2017","unstructured":"Chen SW, Shen WC, Lin YC et al (2017) Correlation of pretreatment (18)F-FDG PET tumor textural features with gene expression in pharyngeal cancer and implications for radiotherapy-based treatment outcomes. Eur J Nucl Med Mol Imaging 44:567\u2013580","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"6452_CR25","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.3109\/0284186X.2015.1061214","volume":"54","author":"RT Leijenaar","year":"2015","unstructured":"Leijenaar RT, Carvalho S, Hoebers FJ et al (2015) External validation of a prognostic CT-based radiomic signature in oropharyngeal squamous cell carcinoma. Acta Oncol 54:1423\u20131429","journal-title":"Acta Oncol"},{"key":"6452_CR26","doi-asserted-by":"publisher","first-page":"3583","DOI":"10.1158\/1078-0432.CCR-17-2507","volume":"24","author":"J Song","year":"2018","unstructured":"Song J, Shi J, Dong D et al (2018) A New Approach to Predict Progression-free Survival in Stage IV EGFR-mutant NSCLC Patients with EGFR-TKI Therapy. Clin Cancer Res 24:3583\u20133592","journal-title":"Clin Cancer Res"},{"key":"6452_CR27","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1007\/s00259-014-2933-1","volume":"42","author":"NM Cheng","year":"2015","unstructured":"Cheng NM, Fang YH, Lee LY et al (2015) Zone-size nonuniformity of 18F-FDG PET regional textural features predicts survival in patients with oropharyngeal cancer. Eur J Nucl Med Mol Imaging 42:419\u2013428","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"6452_CR28","doi-asserted-by":"publisher","unstructured":"Leger S, Zwanenburg A, Pilz K et al (2018) CT imaging during treatment improves radiomic models for patients with locally advanced head and neck cancer. Radiother Oncol. \nhttps:\/\/doi.org\/10.1016\/j.radonc.2018.07.020","DOI":"10.1016\/j.radonc.2018.07.020"},{"key":"6452_CR29","doi-asserted-by":"publisher","first-page":"4006","DOI":"10.1038\/ncomms5006","volume":"5","author":"HJ Aerts","year":"2014","unstructured":"Aerts HJ, Velazquez ER, Leijenaar RT et al (2014) Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach. Nat Commun 5:4006","journal-title":"Nat Commun"},{"key":"6452_CR30","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1002\/lary.21181","volume":"121","author":"UA Patel","year":"2011","unstructured":"Patel UA, Howell LK (2011) Local response to chemoradiation in T4 larynx cancer with cartilage invasion. Laryngoscope 121:106\u2013110","journal-title":"Laryngoscope"},{"key":"6452_CR31","doi-asserted-by":"publisher","first-page":"752","DOI":"10.1111\/dote.12404","volume":"29","author":"EJ Gong","year":"2016","unstructured":"Gong EJ, Kim DH, Ahn JY et al (2016) Routine endoscopic screening for synchronous esophageal neoplasm in patients with head and neck squamous cell carcinoma: a prospective study. Dis Esophagus 29:752\u2013759","journal-title":"Dis Esophagus"},{"key":"6452_CR32","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1186\/s12885-017-3880-6","volume":"17","author":"SY Kim","year":"2017","unstructured":"Kim SY, Rho YS, Choi EC et al (2017) Clinicopathological factors influencing the outcomes of surgical treatment in patients with T4a hypopharyngeal cancer. BMC Cancer 17:904","journal-title":"BMC Cancer"},{"key":"6452_CR33","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1016\/j.anl.2016.08.002","volume":"44","author":"C Scherl","year":"2017","unstructured":"Scherl C, Mantsopoulos K, Semrau S et al (2017) Management of advanced hypopharyngeal and laryngeal cancer with and without cartilage invasion. Auris Nasus Larynx 44:333\u2013339","journal-title":"Auris Nasus Larynx"},{"key":"6452_CR34","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.tranon.2017.10.010","volume":"11","author":"H Zhou","year":"2018","unstructured":"Zhou H, Dong D, Chen B et al (2018) Diagnosis of distant metastasis of lung cancer: based on clinical and radiomic features. Transl Oncol 11:31\u201336","journal-title":"Transl Oncol"},{"key":"6452_CR35","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1001\/jamaoncol.2017.3852","volume":"4","author":"AS Ho","year":"2018","unstructured":"Ho AS, Kim S, Tighiouart M et al (2018) Association of Quantitative Metastatic Lymph Node Burden With Survival in Hypopharyngeal and Laryngeal Cancer. JAMA Oncol 4:985\u2013989","journal-title":"JAMA Oncol"},{"key":"6452_CR36","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1016\/j.oooo.2015.05.023","volume":"120","author":"PM Speight","year":"2015","unstructured":"Speight PM, Abram TJ, Floriano PN et al (2015) Interobserver agreement in dysplasia grading: toward an enhanced gold standard for clinical pathology trials. Oral Surg Oral Med Oral Pathol Oral Radiol 120:474\u2013482 e472","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"6452_CR37","doi-asserted-by":"publisher","unstructured":"Park YW, Oh J, You SC et al (2018) Radiomics and machine learning may accurately predict the grade and histological subtype in meningiomas using conventional and diffusion tensor imaging. Eur Radiol. \nhttps:\/\/doi.org\/10.1007\/s00330-018-5830-3","DOI":"10.1007\/s00330-018-5830-3"},{"key":"6452_CR38","doi-asserted-by":"publisher","unstructured":"Su C, Jiang J, Zhang S et al (2018) Radiomics based on multicontrast MRI can precisely differentiate among glioma subtypes and predict tumour-proliferative behaviour. Eur Radiol. \nhttps:\/\/doi.org\/10.1007\/s00330-018-5704-8","DOI":"10.1007\/s00330-018-5704-8"},{"key":"6452_CR39","doi-asserted-by":"crossref","unstructured":"Chaddad A, Kucharczyk MJ, Niazi T (2018) Multimodal Radiomic Features for the Predicting Gleason Score of Prostate Cancer. Cancers (Basel) 10","DOI":"10.3390\/cancers10080249"}],"container-title":["European Radiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-019-06452-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00330-019-06452-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-019-06452-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T00:21:36Z","timestamp":1603930896000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00330-019-06452-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,30]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["6452"],"URL":"https:\/\/doi.org\/10.1007\/s00330-019-06452-w","relation":{},"ISSN":["0938-7994","1432-1084"],"issn-type":[{"value":"0938-7994","type":"print"},{"value":"1432-1084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,30]]},"assertion":[{"value":"13 April 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 July 2019","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 September 2019","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 October 2019","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The scientific guarantor of this publication is Shuixing Zhang.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Guarantor"}},{"value":"The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"No complex statistical methods were necessary for this paper.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statistics and biometry"}},{"value":"Written informed consent was waived by the Institutional Review Board.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"Institutional Review Board approval was obtained.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"\u2022 retrospective\u2022 diagnostic or prognostic study\/observational\u2022 performed at one institution","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Methodology"}}]}}