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Pain (VAS), shoulder function (SST and DASH), and quality of life (EQ-5D) were assessed at baseline and at 3, 6, and 12\u00a0months post-NACD. Univariate analyses (independent <jats:italic>t<\/jats:italic> tests or Mann-Whitney <jats:italic>U<\/jats:italic> tests depending on the distribution of data) were performed to build a multivariable linear regression model. Stepwise regression analysis through backward elimination was performed to evaluate the effect of predefined prognostic factors on the outcome.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>Patients who underwent multiple NACD procedures had less reduction of pain (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01). Furthermore, a larger reduction in VAS pain scores at 3\u00a0months post-NACD was associated with a larger reduction in VAS pain scores at 12\u00a0months (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01). More improvement of SST and DASH scores at 3\u00a0months was associated with better SST, DASH, and EQ-5D scores at 12\u00a0months (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01). Smaller-size calcific deposits were associated with less improvement of DASH (<jats:italic>p<\/jats:italic>\u2009=\u20090.03) and EQ-5D scores (<jats:italic>p<\/jats:italic>\u2009=\u20090.01). A longer duration of symptoms prior to NACD was associated with less improvement of EQ-5D scores (<jats:italic>p<\/jats:italic>\u2009=\u20090.01).<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>A good initial response after NACD is associated with better outcomes at 12\u00a0months. Patients with a longer duration of symptoms prior to NACD and patients who require multiple procedures showed inferior outcomes in terms of pain reduction and improvement of quality of life. Smaller-size calcific deposits are associated with a less favorable outcome of shoulder function and quality of life scores and might therefore be less susceptible for NACD.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Key Points<\/jats:title>\n<jats:p><jats:italic>\u2022 A good initial response to NACD is associated with a better outcome in the longer term.<\/jats:italic><\/jats:p>\n<jats:p><jats:italic>\u2022 A longer duration of symptoms and the need for multiple NACD procedures are associated with inferior outcomes.<\/jats:italic><\/jats:p>\n<jats:p><jats:italic>\u2022 Smaller-size calcific deposits seem less susceptible for NACD.<\/jats:italic><\/jats:p>\n<\/jats:sec>","DOI":"10.1007\/s00330-020-06669-0","type":"journal-article","created":{"date-parts":[[2020,3,5]],"date-time":"2020-03-05T13:02:51Z","timestamp":1583413371000},"page":"4082-4090","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Prognostic factors for the outcome of needle aspiration of calcific deposits for rotator cuff calcific tendinitis"],"prefix":"10.1007","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7622-8376","authenticated-orcid":false,"given":"Bart W.","family":"Oudelaar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rianne","family":"Huis In \u2018t Veld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Relinde","family":"Schepers-Bok","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin M.","family":"Ooms","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rob G. 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