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Two radiologists independently analyzed the LHC scans for image quality (IQ) and fractures (4-point Likert scales). A specialized forensic preparator dissected the specimens under the stereomicroscope. The PMFP results were standardized documented, and used as the standard of reference for the comparison to PMCT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The PMCT-IQ of 95% of the LHC images was rated as good or excellent. IQ was decreased by decay, incisions during autopsy, and separation of the hyoid from the cartilaginous components in 7, 3, and 12 specimens, respectively. PMFP detected 119 fractures in 34 LHCs (63.0%). PMCT identified 91 fractures in 32 specimens (59.3%). PMFP and PMCT significantly agreed concerning the location (Cohen\u2019s\n                      <jats:italic>\u03ba<\/jats:italic>\n                      \u2009=\u20090.762;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u20090.001) and the degree of dislocation (\n                      <jats:italic>\u03ba<\/jats:italic>\n                      \u2009=\u20090.689;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u20090.001) of the fractures. Comparing PMCT to PMFP resulted in a sensitivity of 88.2%, a specificity of 90.0%, and an ACC of 88.9% for the LHC. The ACCs for the hyoid, thyroid, and cricoid were 94.4%, 87.0%, and 81.5%, respectively. PMCT procedure was significantly faster than PMFP (28.9\u2009\u00b1\u20094.1\u00a0min vs. 208.2\u2009\u00b1\u200932.5\u00a0min;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u20090,001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>PMCT can detect distinct injuries of the isolated LHC and may promptly confirm violence against the neck as cause of death. PMFP outmatches PMCT in the detection of decent injuries like tears of the cricoid cartilage.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key Points<\/jats:title>\n                    <jats:p>\n                      <jats:italic>\u2022 Post-mortem computed tomography is able to assess fractures of the larynx-hyoid complex.<\/jats:italic>\n                    <\/jats:p>\n                    <jats:p>\n                      <jats:italic>\u2022 Prospective monocentric in vitro study showed that post-mortem computed tomography of the larynx-hyoid complex is faster than post-mortem fine preparation.<\/jats:italic>\n                    <\/jats:p>\n                    <jats:p>\n                      <jats:italic>\u2022 Post-mortem computed tomography can confirm violence against the neck as cause of death.<\/jats:italic>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00330-020-06770-4","type":"journal-article","created":{"date-parts":[[2020,3,30]],"date-time":"2020-03-30T21:02:40Z","timestamp":1585602160000},"page":"4564-4572","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Injuries of the isolated larynx-hyoid complex in post-mortem computed tomography (PMCT) and post-mortem fine preparation (PMFP) - a comparison of 54 forensic cases"],"prefix":"10.1007","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3748-4614","authenticated-orcid":false,"given":"Karla Maria","family":"Treitl","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura Isabel","family":"Aigner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evgenij","family":"Gazov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian","family":"Fischer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Regina","family":"Schinner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Schmid-Tannwald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonja","family":"Kirchhoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael Karl","family":"Scherr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,3,31]]},"reference":[{"key":"6770_CR1","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1007\/BF02114619","volume":"80","author":"R Wullenweber","year":"1977","unstructured":"Wullenweber R, Schneider V, Grumme T (1977) A computer-tomographical examination of cranial bullet wounds (author\u2019s transl). 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Michael Karl Scherr.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Guarantor"}},{"value":"The authors declare that they have no conflict of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"R. Schinner, Dipl.-Stat. kindly provided statistical advice for this manuscript.Karla Maria Treitl, one of the authors, has significant statistical expertise.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statistics and biometry"}},{"value":"Written informed consent was not required for this study because the investigated specimens were larynx-hyoid complexes that were extracted during autopsy from forensic cases (dead bodies) that required a post-mortem fine-preparation of the larynx-hyoid complex additional to autopsy in order to confirm or disprove the suspicion of violent neck injuries.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The study was approved by the institutional ethical review board of the Faculty of Medicine of the LMU Munich (proposal no. 151\/08, date of approval: February 12, 2008).","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"\u2022 Prospective\u2022 Cross-sectional study\u2022 Performed at one institution","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Methodology"}}]}}