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From patients\u2019 medical records, we obtained their history including previous and current diseases and medications. For each patient, we calculated relative length (RL), sum of angle metrics (SOAM), triangular index (TI), product of angle distance (PAD) and inflexion count metrics (ICM). We used <jats:italic>t<\/jats:italic>-test and Mann-Whitney <jats:italic>U<\/jats:italic> test for continuous variables and <jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup> test for dichotomised variables. To find independent predictors of BA aneurysm, we employed logistic regression analysis.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>We found significant positive correlation between age and SOAM (<jats:italic>R<\/jats:italic>\u2009=\u20090.195, <jats:italic>p<\/jats:italic>\u2009=\u20090.02) and PAD (<jats:italic>R<\/jats:italic>\u2009=\u20090.199, <jats:italic>p<\/jats:italic>\u2009=\u20090.018). Our study also showed that patients with BA aneurysm had significantly higher SOAM (0.21\u2009\u00b1\u20090.16 vs. 0.11\u2009\u00b1\u20090.08; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01), PAD (0.30\u2009\u00b1\u20090.19 vs. 0.18\u2009\u00b1\u20090.11; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01), TI (0.23\u2009\u00b1\u20090.23 vs. 0.10\u2009\u00b1\u20090.16; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01) and ICM (0.20\u2009\u00b1\u20090.16 vs. 0.15\u2009\u00b1\u20090.11; <jats:italic>p<\/jats:italic>\u2009=\u20090.045). In multivariate logistic regression analysis, after adjustment for all possible confounders, SOAM (OR\u2009=\u20091.086; 95% CI 1.046\u20131.136; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01) and TI (OR\u2009=\u20091.004; 95%C: 1.002\u20131.006; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01) remained independently associated with higher risk of BA aneurysm.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Increased tortuosity of BA is associated with higher risk of its aneurysm development.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Key Points<\/jats:title>\n<jats:p><jats:italic>\u2022 Basilar artery sum of angle metrics and product of angle distance are correlated with age.<\/jats:italic><\/jats:p>\n<jats:p><jats:italic>\u2022 Basilar artery tortuosity is independently associated with higher risk of its aneurysm development.<\/jats:italic><\/jats:p>\n<jats:p><jats:italic>\u2022 Basilar artery tortuosity is positively correlated with its diameter and bifurcation angle.<\/jats:italic><\/jats:p>\n<\/jats:sec>","DOI":"10.1007\/s00330-020-06917-3","type":"journal-article","created":{"date-parts":[[2020,5,13]],"date-time":"2020-05-13T13:03:28Z","timestamp":1589375008000},"page":"5625-5632","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Increased tortuosity of basilar artery might be associated with higher risk of aneurysm development"],"prefix":"10.1007","volume":"30","author":[{"given":"Kornelia M.","family":"Kli\u015b","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3580-0599","authenticated-orcid":false,"given":"Roger M.","family":"Krzy\u017cewski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Borys M.","family":"Kwinta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart\u0142omiej","family":"\u0141asocha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawe\u0142","family":"Brzegowy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krzysztof","family":"Stachura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadeusz J.","family":"Popiela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rados\u0142aw","family":"Borek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerzy","family":"G\u0105sowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,5,13]]},"reference":[{"key":"6917_CR1","doi-asserted-by":"crossref","unstructured":"Han HC (2012) Twisted blood vessels: symptoms, etiology and biomechanical mechanisms. 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