{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T22:26:07Z","timestamp":1787869567699,"version":"build-2784847793"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,8,12]],"date-time":"2020-08-12T00:00:00Z","timestamp":1597190400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,8,12]],"date-time":"2020-08-12T00:00:00Z","timestamp":1597190400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National research foundation of Korea","doi-asserted-by":"crossref","award":["NRF-2016R1A2B4012155"],"award-info":[{"award-number":["NRF-2016R1A2B4012155"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003725","name":"National research foundation of Korea","doi-asserted-by":"crossref","award":["NRF-2018R1D1A1B07049989"],"award-info":[{"award-number":["NRF-2018R1D1A1B07049989"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"crossref"}]},{"name":"korea university Ansan hospital","award":["O1700681"],"award-info":[{"award-number":["O1700681"]}]},{"name":"korea university Ansan hospital","award":["O1801231"],"award-info":[{"award-number":["O1801231"]}]},{"name":"korea university Ansan hospital","award":["O1903391"],"award-info":[{"award-number":["O1903391"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Radiol"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1007\/s00330-020-07104-0","type":"journal-article","created":{"date-parts":[[2020,8,12]],"date-time":"2020-08-12T14:02:31Z","timestamp":1597240951000},"page":"515-524","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Nitrates administered by spray versus tablet: comparison of coronary vasodilation on CT angiography"],"prefix":"10.1007","volume":"31","author":[{"given":"Cherry","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moin","family":"Ha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wooil","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung-Joon","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Ho","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hwan Seok","family":"Yong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Whan","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun-Young","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaehyung","family":"Cha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Hwa","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0323-1280","authenticated-orcid":false,"given":"Ki Yeol","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,8,12]]},"reference":[{"key":"7104_CR1","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1056\/NEJM199802193380807","volume":"338","author":"JD Parker","year":"1998","unstructured":"Parker JD, Parker JO (1998) Nitrate therapy for stable angina pectoris. N Engl J Med 338:520\u2013531","journal-title":"N Engl J Med"},{"key":"7104_CR2","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1016\/j.jcct.2016.10.002","volume":"10","author":"S Abbara","year":"2016","unstructured":"Abbara S, Blanke P, Maroules CD et al (2016) SCCT guidelines for the performance and acquisition of coronary computed tomographic angiography: a report of the Society of Cardiovascular Computed Tomography Guidelines Committee: endorsed by the North American Society for Cardiovascular Imaging (NASCI). J Cardiovasc Comput Tomogr 10:435\u2013449","journal-title":"J Cardiovasc Comput Tomogr"},{"key":"7104_CR3","doi-asserted-by":"publisher","first-page":"3536","DOI":"10.1007\/s00330-015-3791-3","volume":"25","author":"RA Takx","year":"2015","unstructured":"Takx RA, Sucha D, Park J, Leiner T, Hoffmann U (2015) Sublingual nitroglycerin administration in coronary computed tomography angiography: a systematic review. Eur Radiol 25:3536\u20133542","journal-title":"Eur Radiol"},{"key":"7104_CR4","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1136\/hrt.80.4.365","volume":"80","author":"M Pfister","year":"1998","unstructured":"Pfister M, Seiler C, Fleisch M, Gobel H, Luscher T, Meier B (1998) Nitrate induced coronary vasodilatation: differential effects of sublingual application by capsule or spray. Heart 80:365\u2013369","journal-title":"Heart"},{"key":"7104_CR5","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1159\/000174612","volume":"77","author":"LJ Laslett","year":"1990","unstructured":"Laslett LJ, Baker L (1990) Sublingual nitroglycerin administered by spray versus tablet: comparative timing of hemodynamic effects. Cardiology 77:303\u2013310","journal-title":"Cardiology"},{"key":"7104_CR6","first-page":"707","volume":"34","author":"M Saito","year":"1984","unstructured":"Saito M, Fukami K, Sumiyoshi T, Haze K, Hiramori K (1984) Effects of isosorbide dinitrate spray on central hemodynamics. Comparison with sublingual glyceryl trinitrate and isosorbide dinitrate. Arzneimittelforschung 34:707\u2013709","journal-title":"Arzneimittelforschung"},{"key":"7104_CR7","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1016\/j.jcct.2014.07.003","volume":"8","author":"J Leipsic","year":"2014","unstructured":"Leipsic J, Abbara S, Achenbach S et al (2014) SCCT guidelines for the interpretation and reporting of coronary CT angiography: a report of the Society of Cardiovascular Computed Tomography Guidelines Committee. J Cardiovasc Comput Tomogr 8:342\u2013358","journal-title":"J Cardiovasc Comput Tomogr"},{"key":"7104_CR8","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/j.jcct.2016.04.005","volume":"10","author":"RC Cury","year":"2016","unstructured":"Cury RC, Abbara S, Achenbach S et al (2016) CAD-RADS(TM) Coronary Artery Disease - Reporting and Data System. An expert consensus document of the Society of Cardiovascular Computed Tomography (SCCT), the American College of Radiology (ACR) and the North American Society for Cardiovascular Imaging (NASCI). Endorsed by the American College of Cardiology. J Cardiovasc Comput Tomogr 10:269\u2013281","journal-title":"J Cardiovasc Comput Tomogr"},{"key":"7104_CR9","doi-asserted-by":"publisher","first-page":"937","DOI":"10.3349\/ymj.2018.59.8.937","volume":"59","author":"C Kim","year":"2018","unstructured":"Kim C, Hong SJ, Ahn CM et al (2018) Clinical implications of moderate coronary stenosis on coronary computed tomography angiography in patients with stable angina. Yonsei Med J 59:937\u2013944","journal-title":"Yonsei Med J"},{"key":"7104_CR10","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1002\/bdd.2510140203","volume":"14","author":"SH Curry","year":"1993","unstructured":"Curry SH, Lopez LM, Lambert CR, Kwon HR, Stack RK (1993) Plasma concentrations and hemodynamic effects of intravenous, sublingual, and aerosolized nitroglycerin in patients undergoing cardiac catheterization. Biopharm Drug Dispos 14:107\u2013118","journal-title":"Biopharm Drug Dispos"},{"key":"7104_CR11","doi-asserted-by":"publisher","first-page":"43j","DOI":"10.1016\/0002-9149(90)91311-S","volume":"65","author":"A Marmor","year":"1990","unstructured":"Marmor A (1990) Comparative evaluation of a new formulation of isosorbide dinitrate oral spray and sublingual nitroglycerin tablets. Am J Cardiol 65:43j\u201345j","journal-title":"Am J Cardiol"},{"key":"7104_CR12","doi-asserted-by":"publisher","first-page":"2e","DOI":"10.1016\/0002-9149(88)90079-3","volume":"61","author":"LH Reisin","year":"1988","unstructured":"Reisin LH, Landau E, Darawshi A (1988) More rapid relief of pain with isosorbide dinitrate oral spray than with sublingual tablets in elderly patients with angina pectoris. Am J Cardiol 61:2e\u20133e","journal-title":"Am J Cardiol"},{"key":"7104_CR13","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1007\/BF00051192","volume":"2","author":"N Marchionni","year":"1988","unstructured":"Marchionni N, De Bari M, Ferrucci L, Moschi G, Schneeweiss A (1988) Comparative study of time-course of hemodynamic effect of isosorbide dinitrate spray and sublingual tablets in patients with pulmonary congestion. Cardiovasc Drugs Ther 2:529\u2013532","journal-title":"Cardiovasc Drugs Ther"},{"key":"7104_CR14","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1007\/s12013-014-0494-3","volume":"72","author":"P Zhang","year":"2015","unstructured":"Zhang P (2015) Influence of nitroglycerin on coronary artery CT imaging in cardiovascular diseases. Cell Biochem Biophys 72:497\u2013501","journal-title":"Cell Biochem Biophys"},{"key":"7104_CR15","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1016\/j.ijcard.2016.06.050","volume":"219","author":"T Maruhashi","year":"2016","unstructured":"Maruhashi T, Kajikawa M, Nakashima A et al (2016) Nitroglycerine-induced vasodilation in coronary and brachial arteries in patients with suspected coronary artery disease. Int J Cardiol 219:312\u2013316","journal-title":"Int J Cardiol"},{"key":"7104_CR16","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1097\/rct.0b013e318059befa","volume":"32","author":"EJ Chun","year":"2008","unstructured":"Chun EJ, Lee W, Choi YH et al (2008) Effects of nitroglycerin on the diagnostic accuracy of electrocardiogram-gated coronary computed tomography angiography. J Comput Assist Tomogr 32:86\u201392","journal-title":"J Comput Assist Tomogr"},{"key":"7104_CR17","doi-asserted-by":"publisher","first-page":"219","DOI":"10.2214\/AJR.07.2648","volume":"190","author":"I Decramer","year":"2008","unstructured":"Decramer I, Vanhoenacker PK, Sarno G et al (2008) Effects of sublingual nitroglycerin on coronary lumen diameter and number of visualized septal branches on 64-MDCT angiography. AJR Am J Roentgenol 190:219\u2013225","journal-title":"AJR Am J Roentgenol"},{"key":"7104_CR18","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.acra.2007.07.023","volume":"15","author":"J Zhang","year":"2008","unstructured":"Zhang J, Fletcher JG, Scott Harmsen W et al (2008) Analysis of heart rate and heart rate variation during cardiac CT examinations. Acad Radiol 15:40\u201348","journal-title":"Acad Radiol"},{"key":"7104_CR19","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1097\/RCT.0b013e31817c6b33","volume":"33","author":"O Klass","year":"2009","unstructured":"Klass O, Mutlu S, Hohl K et al (2009) Multidetector computed tomography coronary angiography: sublingual nitroglycerine improves image quality significantly because of peripheral coronary vasodilatation. J Comput Assist Tomogr 33:199\u2013203","journal-title":"J Comput Assist Tomogr"},{"key":"7104_CR20","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1097\/RCT.0b013e31817f455a","volume":"33","author":"K Sato","year":"2009","unstructured":"Sato K, Isobe S, Sugiura K et al (2009) Optimal starting time of acquisition and feasibility of complementary administration of nitroglycerin with intravenous beta-blocker in multislice computed tomography. J Comput Assist Tomogr 33:193\u2013198","journal-title":"J Comput Assist Tomogr"},{"key":"7104_CR21","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1016\/j.jjcc.2014.05.012","volume":"65","author":"M Okada","year":"2015","unstructured":"Okada M, Nakashima Y, Nomura T et al (2015) Coronary vasodilation by the use of sublingual nitroglycerin using 64-slice dual-source coronary computed tomography angiography. J Cardiol 65:230\u2013236","journal-title":"J Cardiol"},{"key":"7104_CR22","doi-asserted-by":"publisher","first-page":"600","DOI":"10.1055\/s-2006-926755","volume":"178","author":"M Dewey","year":"2006","unstructured":"Dewey M, Hoffmann H, Hamm B (2006) Multislice CT coronary angiography: effect of sublingual nitroglycerine on the diameter of coronary arteries. Rofo 178:600\u2013604","journal-title":"Rofo"}],"container-title":["European Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-020-07104-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00330-020-07104-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-020-07104-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,11]],"date-time":"2021-08-11T23:26:31Z","timestamp":1628724391000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00330-020-07104-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,12]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["7104"],"URL":"https:\/\/doi.org\/10.1007\/s00330-020-07104-0","relation":{},"ISSN":["0938-7994","1432-1084"],"issn-type":[{"value":"0938-7994","type":"print"},{"value":"1432-1084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,12]]},"assertion":[{"value":"11 December 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 May 2020","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 July 2020","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 August 2020","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The scientific guarantor of this publication is Ki Yeol Lee.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Guarantor"}},{"value":"The authors of this manuscript declare no relationships with any companies whose products or services may be related to the subject matter of the article.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"One of the authors has significant statistical expertise.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statistics and biometry"}},{"value":"Written informed consent was waived by the institutional review board.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"Institutional review board approval was obtained.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"\u2022 retrospective\u2022 observational\u2022 performed at one institution","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Methodology"}}]}}