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De Buyser, Biostatistics Unit, Faculty of Medicine and Health Sciences Ghent University) has significant statistical expertise.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statistics and biometry"}},{"value":"Written informed consent was obtained from all subjects (patients and their parents) in this study.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"Institutional Review Board approval was obtained.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Some study subjects or cohorts have been previously reported in some of our previous reports on other topics (77\/251 patients). We have published on pediatric patients with low back pain or established spondyloarthritis. This is our first manuscript focused on normal children with no history of back pain. This manuscript focuses on new data on a unique group of 127 \u201cnormal\u201d patients, with asymptomatic sacroiliacal joints who were being imaged for non-rheumatologic conditions, of whom we have not published before. We compare findings in this group to a set of 124 \u201cLBP\u201d patients whom we have previously analyzed, who did not show features of sacroiliitis at initial clinical MRI review but who presented with inflammatory back pain symptoms. The high similarity we note in physiologic findings between findings in the normal and \u201cLBP\u201d cohorts is an important observation that can help guide study design for future research in this field.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Study subjects or cohorts overlap"}},{"value":"\u2022 prospective\u2022 observational\u2022 performed at one institution","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Methodology"}}]}}