{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T10:27:20Z","timestamp":1792492040306,"version":"4.5.0"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T00:00:00Z","timestamp":1604016000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T00:00:00Z","timestamp":1604016000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Radiol"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1007\/s00330-020-07421-4","type":"journal-article","created":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T02:02:26Z","timestamp":1604023346000},"page":"2886-2895","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["A CT-based radiomics nomogram for differentiation of lympho-associated benign and malignant lesions of the parotid gland"],"prefix":"10.1007","volume":"31","author":[{"given":"Ying-mei","family":"Zheng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-jian","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Da-peng","family":"Hao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue-jun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuan-ping","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo-zhang","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"He-xiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1903-2291","authenticated-orcid":false,"given":"Cheng","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,10,30]]},"reference":[{"key":"7421_CR1","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1007\/s12663-016-0882-x","volume":"15","author":"S Aydin","year":"2016","unstructured":"Aydin S, Demir MG, Barisik NO (2016) Extranodal marginal zone lymphoma of the parotid gland. J Maxillofac Oral Surg 15:346\u2013350","journal-title":"J Maxillofac Oral Surg"},{"key":"7421_CR2","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.3324\/haematol.2009.005983","volume":"94","author":"RJ Bende","year":"2009","unstructured":"Bende RJ, van Maldegem F, van Noesel CJ (2009) Chronic inflammatory disease, lymphoid tissue neogenesis and extranodal marginal zone B-cell lymphomas. Haematologica 94:1109\u20131123","journal-title":"Haematologica"},{"key":"7421_CR3","doi-asserted-by":"publisher","first-page":"e17042","DOI":"10.1097\/MD.0000000000017042","volume":"98","author":"JH Hwang","year":"2019","unstructured":"Hwang JH, Kim DW, Kim KS, Lee SY (2019) Mucosa-associated lymphoid tissue lymphoma of the accessory parotid gland presenting as a simple cheek mass: a case report. Medicine (Baltimore) 98:e17042","journal-title":"Medicine (Baltimore)"},{"key":"7421_CR4","doi-asserted-by":"publisher","first-page":"1563","DOI":"10.2214\/ajr.178.6.1781563","volume":"178","author":"BB Tagnon","year":"2002","unstructured":"Tagnon BB, Theate I, Weynand B, Hamoir M, Coche EE (2002) Long-standing mucosa-associated lymphoid tissue lymphoma of the parotid gland: CT and MR imaging findings. AJR Am J Roentgenol 178:1563\u20131565","journal-title":"AJR Am J Roentgenol"},{"key":"7421_CR5","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1097\/00001622-199605000-00011","volume":"8","author":"JA DiGiuseppe","year":"1996","unstructured":"DiGiuseppe JA, Corio RL, Westra WH (1996) Lymphoid infiltrates of the salivary glands: pathology, biology and clinical significance. Curr Opin Oncol 8:232\u2013237","journal-title":"Curr Opin Oncol"},{"key":"7421_CR6","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/S0385-8146(01)00144-4","volume":"29","author":"K Sato","year":"2002","unstructured":"Sato K, Kawana M, Sato Y, Takahashi S (2002) Malignant lymphoma in the head and neck associated with benign lymphoepithelial lesion of the parotid gland. Auris Nasus Larynx 29:209\u2013214","journal-title":"Auris Nasus Larynx"},{"key":"7421_CR7","doi-asserted-by":"publisher","first-page":"20130046","DOI":"10.1259\/dmfr.20130046","volume":"42","author":"L Zhu","year":"2013","unstructured":"Zhu L, Wang P, Yang J, Yu Q (2013) Non-Hodgkin lymphoma involving the parotid gland: CT and MR imaging findings. Dentomaxillofac Radiol 42:20130046","journal-title":"Dentomaxillofac Radiol"},{"key":"7421_CR8","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1002\/jmri.26260","volume":"49","author":"L Zhu","year":"2019","unstructured":"Zhu L, Wang J, Shi H, Tao X (2019) Multimodality fMRI with perfusion, diffusion-weighted MRI and (1) H-MRS in the diagnosis of lympho-associated benign and malignant lesions of the parotid gland. J Magn Reson Imaging 49:423\u2013432","journal-title":"J Magn Reson Imaging"},{"key":"7421_CR9","doi-asserted-by":"publisher","first-page":"20150343","DOI":"10.1259\/dmfr.20150343","volume":"45","author":"L Zhu","year":"2016","unstructured":"Zhu L, Zhang C, Hua Y et al (2016) Dynamic contrast-enhanced MR in the diagnosis of lympho-associated benign and malignant lesions in the parotid gland. Dentomaxillofac Radiol 45:20150343","journal-title":"Dentomaxillofac Radiol"},{"key":"7421_CR10","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1148\/radiol.2015151169","volume":"278","author":"RJ Gillies","year":"2016","unstructured":"Gillies RJ, Kinahan PE, Hricak H (2016) Radiomics: images are more than pictures, they are data. Radiology 278:563\u2013577","journal-title":"Radiology"},{"key":"7421_CR11","doi-asserted-by":"publisher","first-page":"1343","DOI":"10.3174\/ajnr.A4285","volume":"36","author":"K Buch","year":"2015","unstructured":"Buch K, Fujita A, Li B, Kawashima Y, Qureshi MM, Sakai O (2015) Using texture analysis to determine human papillomavirus status of oropharyngeal squamous cell carcinomas on CT. AJNR Am J Neuroradiol 36:1343\u20131348","journal-title":"AJNR Am J Neuroradiol"},{"key":"7421_CR12","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1016\/j.radonc.2013.09.019","volume":"109","author":"E Scalco","year":"2013","unstructured":"Scalco E, Fiorino C, Cattaneo GM, Sanguineti G, Rizzo G (2013) Texture analysis for the assessment of structural changes in parotid glands induced by radiotherapy. Radiother Oncol 109:384\u2013387","journal-title":"Radiother Oncol"},{"key":"7421_CR13","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1186\/s13014-019-1339-4","volume":"14","author":"K Sheikh","year":"2019","unstructured":"Sheikh K, Lee SH, Cheng Z et al (2019) Predicting acute radiation induced xerostomia in head and neck cancer using MR and CT radiomics of parotid and submandibular glands. Radiat Oncol 14:131","journal-title":"Radiat Oncol"},{"key":"7421_CR14","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.artmed.2017.03.004","volume":"81","author":"M Pota","year":"2017","unstructured":"Pota M, Scalco E, Sanguineti G et al (2017) Early prediction of radiotherapy-induced parotid shrinkage and toxicity based on CT radiomics and fuzzy classification. Artif Intell Med 81:41\u201353","journal-title":"Artif Intell Med"},{"key":"7421_CR15","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.mbs.2018.06.004","volume":"303","author":"R Alhamzawi","year":"2018","unstructured":"Alhamzawi R, Ali HTM (2018) The Bayesian adaptive lasso regression. Math Biosci 303:75\u201382","journal-title":"Math Biosci"},{"key":"7421_CR16","doi-asserted-by":"publisher","unstructured":"Wang T, Gao T, Guo H et al (2020) Preoperative prediction of parametrial invasion in early-stage cervical cancer with MRI-based radiomics nomogram. Eur Radiol. https:\/\/doi.org\/10.1007\/s00330-019-06655-1","DOI":"10.1007\/s00330-019-06655-1"},{"key":"7421_CR17","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1111\/j.1365-2753.2005.00598.x","volume":"12","author":"A Linden","year":"2006","unstructured":"Linden A (2006) Measuring diagnostic and predictive accuracy in disease management: an introduction to receiver operating characteristic (ROC) analysis. J Eval Clin Pract 12:132\u2013139","journal-title":"J Eval Clin Pract"},{"key":"7421_CR18","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1177\/0194599815607841","volume":"154","author":"CC Liu","year":"2016","unstructured":"Liu CC, Jethwa AR, Khariwala SS, Johnson J, Shin JJ (2016) Sensitivity, specificity, and posttest probability of parotid fine-needle aspiration: a systematic review and meta-analysis. Otolaryngol Head Neck Surg 154:9\u201323","journal-title":"Otolaryngol Head Neck Surg"},{"key":"7421_CR19","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1309\/AJCPOIE0CZNAT6SQ","volume":"136","author":"RL Schmidt","year":"2011","unstructured":"Schmidt RL, Hall BJ, Wilson AR, Layfield LJ (2011) A systematic review and meta-analysis of the diagnostic accuracy of fine-needle aspiration cytology for parotid gland lesions. Am J Clin Pathol 136:45\u201359","journal-title":"Am J Clin Pathol"},{"key":"7421_CR20","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1067\/moe.2001.116062","volume":"92","author":"JB Epstein","year":"2001","unstructured":"Epstein JB, Epstein JD, Le ND, Gorsky M (2001) Characteristics of oral and paraoral malignant lymphoma: a population-based review of 361 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 92:519\u2013525","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"7421_CR21","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1111\/coa.12635","volume":"42","author":"A Lieder","year":"2017","unstructured":"Lieder A, Franzen A (2017) Management of primary malignant lymphoma of the parotid gland in a series of seven hundred and forty-five patients. Clin Otolaryngol 42:477\u2013480","journal-title":"Clin Otolaryngol"},{"key":"7421_CR22","doi-asserted-by":"publisher","first-page":"921","DOI":"10.2214\/AJR.07.2629","volume":"191","author":"O Maksimovic","year":"2008","unstructured":"Maksimovic O, Bethge WA, Pintoffl JP et al (2008) Marginal zone B-cell non-Hodgkin\u2019s lymphoma of mucosa-associated lymphoid tissue type: imaging findings. AJR Am J Roentgenol 191:921\u2013930","journal-title":"AJR Am J Roentgenol"},{"key":"7421_CR23","doi-asserted-by":"publisher","first-page":"32","DOI":"10.11152\/mu-923","volume":"19","author":"V Cantisani","year":"2017","unstructured":"Cantisani V, David E, De Virgilio A et al (2017) Prospective evaluation of quasistatic ultrasound elastography (USE) compared with baseline US for parotid gland lesions: preliminary results of elasticity contrast index (ECI) evaluation. Med Ultrason 19:32\u201338","journal-title":"Med Ultrason"},{"key":"7421_CR24","first-page":"166","volume":"38","author":"N Mansour","year":"2017","unstructured":"Mansour N, Bas M, Stock KF, Strassen U, Hofauer B, Knopf A (2017) Multimodal ultrasonographic pathway of parotid gland lesions. Ultraschall Med 38:166\u2013173","journal-title":"Ultraschall Med"},{"key":"7421_CR25","doi-asserted-by":"publisher","first-page":"77","DOI":"10.7863\/ultra.16.02038","volume":"36","author":"NK Altinbas","year":"2017","unstructured":"Altinbas NK, Gundogdu Anamurluoglu E, Oz II et al (2017) Real-time sonoelastography of parotid gland tumors. J Ultrasound Med 36:77\u201387","journal-title":"J Ultrasound Med"},{"key":"7421_CR26","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1007\/s00330-018-5609-6","volume":"29","author":"YF Zhang","year":"2019","unstructured":"Zhang YF, Li H, Wang XM, Cai YF (2019) Sonoelastography for differential diagnosis between malignant and benign parotid lesions: a meta-analysis. Eur Radiol 29:725\u2013735","journal-title":"Eur Radiol"},{"key":"7421_CR27","doi-asserted-by":"publisher","first-page":"371","DOI":"10.21037\/tcr.2016.07.18","volume":"5","author":"AJ Wong","year":"2016","unstructured":"Wong AJ, Kanwar A, Mohamed AS, Fuller CD (2016) Radiomics in head and neck cancer: from exploration to application. Transl Cancer Res 5:371\u2013382","journal-title":"Transl Cancer Res"},{"key":"7421_CR28","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1159\/000455704","volume":"79","author":"K Scheckenbach","year":"2017","unstructured":"Scheckenbach K, Colter L, Wagenmann M (2017) Radiomics in head and neck cancer: extracting valuable information from data beyond recognition. ORL J Otorhinolaryngol Relat Spec 79:65\u201371","journal-title":"ORL J Otorhinolaryngol Relat Spec"},{"key":"7421_CR29","doi-asserted-by":"publisher","first-page":"2604","DOI":"10.1007\/s00330-017-5214-0","volume":"28","author":"E Al Ajmi","year":"2018","unstructured":"Al Ajmi E, Forghani B, Reinhold C, Bayat M, Forghani R (2018) Spectral multi-energy CT texture analysis with machine learning for tissue classification: an investigation using classification of benign parotid tumours as a testing paradigm. Eur Radiol 28:2604\u20132611","journal-title":"Eur Radiol"},{"key":"7421_CR30","doi-asserted-by":"publisher","first-page":"1372","DOI":"10.1002\/nbm.2962","volume":"26","author":"J Fruehwald-Pallamar","year":"2013","unstructured":"Fruehwald-Pallamar J, Czerny C, Holzer-Fruehwald L et al (2013) Texture-based and diffusion-weighted discrimination of parotid gland lesions on MR images at 3.0 Tesla. NMR Biomed 26:1372\u20131379","journal-title":"NMR Biomed"},{"key":"7421_CR31","first-page":"195","volume":"188","author":"J Fruehwald-Pallamar","year":"2016","unstructured":"Fruehwald-Pallamar J, Hesselink JR, Mafee MF, Holzer-Fruehwald L, Czerny C, Mayerhoefer ME (2016) Texture-based analysis of 100 MR examinations of head and neck tumors - is it possible to discriminate between benign and malignant masses in a multicenter trial? Rofo 188:195\u2013202","journal-title":"Rofo"},{"key":"7421_CR32","doi-asserted-by":"publisher","first-page":"976","DOI":"10.1007\/s00330-019-06398-z","volume":"30","author":"Y Wang","year":"2020","unstructured":"Wang Y, Liu W, Yu Y et al (2020) CT radiomics nomogram for the preoperative prediction of lymph node metastasis in gastric cancer. Eur Radiol 30:976\u2013986","journal-title":"Eur Radiol"},{"key":"7421_CR33","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1007\/s00330-019-06211-x","volume":"30","author":"L Zhao","year":"2020","unstructured":"Zhao L, Gong J, Xi Y et al (2020) MRI-based radiomics nomogram may predict the response to induction chemotherapy and survival in locally advanced nasopharyngeal carcinoma. Eur Radiol 30:537\u2013546","journal-title":"Eur Radiol"},{"key":"7421_CR34","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1007\/s00330-018-5539-3","volume":"29","author":"T Hu","year":"2019","unstructured":"Hu T, Wang S, Huang L et al (2019) A clinical-radiomics nomogram for the preoperative prediction of lung metastasis in colorectal cancer patients with indeterminate pulmonary nodules. Eur Radiol 29:439\u2013449","journal-title":"Eur Radiol"},{"key":"7421_CR35","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1007\/s00330-018-5581-1","volume":"29","author":"X Tan","year":"2019","unstructured":"Tan X, Ma Z, Yan L, Ye W, Liu Z, Liang C (2019) Radiomics nomogram outperforms size criteria in discriminating lymph node metastasis in resectable esophageal squamous cell carcinoma. Eur Radiol 29:392\u2013400","journal-title":"Eur Radiol"}],"container-title":["European Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-020-07421-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00330-020-07421-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-020-07421-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T10:31:09Z","timestamp":1618309869000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00330-020-07421-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,30]]},"references-count":35,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["7421"],"URL":"https:\/\/doi.org\/10.1007\/s00330-020-07421-4","relation":{},"ISSN":["0938-7994","1432-1084"],"issn-type":[{"value":"0938-7994","type":"print"},{"value":"1432-1084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,30]]},"assertion":[{"value":"18 June 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 September 2020","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 October 2020","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 October 2020","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The scientific guarantor of this publication is Da-peng Hao.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Guarantor"}},{"value":"The authors declare that they have no conflict of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"One of the authors (Da-peng Hao) has significant statistical expertise and is identified as the statistical guarantor for the statistical analysis used in this study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statistics and biometry"}},{"value":"Written informed consent was obtained from all subjects (patients) in this study.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"Institutional Review Board approval was obtained.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"\u2022 retrospective\u2022 diagnostic study\/observational\/\u2022 performed at one institution","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Methodology"}}]}}