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Additionally, a control group of 10 children has been examined according to the same protocol. Lung spirometry was additionally available in 43 patients of the CDH group. A comparison of ipsilateral and contralateral parameters was performed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Pulmonary blood flow (PBF) was reduced on the ipsilateral side in CDH patients (60.4\u2009\u00b1\u200923.8 vs. 93.3\u2009\u00b1\u200916.09\u00a0mL\/100\u00a0mL\/min; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001). In comparison to the control group, especially the ratio of ipsilateral to contralateral, PBF was reduced in CDH patients (0.669\u2009\u00b1\u20090.152 vs. 0.975\u2009\u00b1\u20090.091; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001). There is a positive correlation between ipsilateral pulmonary blood flow, and spirometric forced 1-s volume (<jats:italic>r<\/jats:italic>\u2009=\u20090.45; <jats:italic>p<\/jats:italic>\u2009=\u20090.0024).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Pulmonary blood flow impairment persists during childhood and correlates with spirometric measurements. Without the need for ionizing radiation, MRI measurements seem promising as follow-up parameters after CDH.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Key Points<\/jats:title>\n                <jats:p><jats:italic>\u2022 Ten-year-old children after congenital diaphragmatic hernia continue to show reduced perfusion of ipsilateral lung.<\/jats:italic><\/jats:p>\n                <jats:p><jats:italic>\u2022 Lung perfusion values correlate with lung function tests after congenital diaphragmatic hernia.<\/jats:italic><\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00330-021-08315-9","type":"journal-article","created":{"date-parts":[[2021,11,6]],"date-time":"2021-11-06T08:02:43Z","timestamp":1636185763000},"page":"2572-2580","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["MR lung perfusion measurements in adolescents after congenital diaphragmatic hernia: correlation with spirometric lung function tests"],"prefix":"10.1007","volume":"32","author":[{"given":"Verena","family":"Gro\u00df","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrin","family":"Zahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina","family":"Maurer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas","family":"Wessel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Schaible","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan O.","family":"Schoenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christel","family":"Wei\u00df","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank G.","family":"Zoellner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8085-6612","authenticated-orcid":false,"given":"Meike","family":"Weis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,11,6]]},"reference":[{"key":"8315_CR1","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1159\/000444210","volume":"110","author":"KG Snoek","year":"2016","unstructured":"Snoek KG, Reiss IK, Greenough A et al (2016) Standardized postnatal management of infants with congenital diaphragmatic hernia in Europe: The CDH EURO Consortium Consensus - 2015 Update. 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Funding note \"Open Access funding enabled and organized by Projekt DEAL\" has been added.","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The scientific guarantor of this publication is PD Dr.med. Meike Weis, MSc.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Guarantor"}},{"value":"The authors of this manuscript declare no relationships with any companies whose products or services may be related to the subject matter of the article.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"One of the authors has significant statistical expertise (Prof. Dr. Christel Wei\u00df).","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statistics and biometry"}},{"value":"Written informed consent was obtained from all subjects (patients) in this study.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"Institutional Review Board approval was obtained.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Fifteen patients of our current cohort (54 patients) have been examined at the age of 2\u00a0years. Four of them with identical study protocol. Now, they have been re-examined at the age of 10\u00a0years.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Study subjects or cohorts overlap"}},{"value":"\u2022 retrospective\u2022 diagnostic or prognostic study\u2022 performed at one institution","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Methodology"}}]}}