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Axial T2-w, coronal T1-w, and coronal\/sagittal intermediate-w scans with fat saturation were acquired using compressed sensing only (12:44 min, CS), CSAI with an acceleration factor of 4.6\u20135.3 (6:45 min, CSAI2x), and CSAI with an acceleration factor of 6.9\u20137.7 (4:46 min, CSAI3x). Moreover, a high-resolution axial T2-w scan was obtained using CSAI with a similar scan duration compared to CS. Depiction and presence of abnormalities were graded. Signal-to-noise and contrast-to-noise were calculated. Wilcoxon signed-rank test and Cohen\u2019s kappa were used to compare CSAI with CS sequences.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The correlation was perfect between CS and CSAI2x (<jats:italic>\u03ba<\/jats:italic> = 1.0) and excellent for CS and CSAI3x (<jats:italic>\u03ba<\/jats:italic> = 0.86\u20131.0). No significant differences were found for the depiction of structures between CS and CSAI2x and the same abnormalities were detected in both protocols. For CSAI3x the depiction was graded lower (<jats:italic>p<\/jats:italic> \u2264 0.001), though most abnormalities were also detected. For CSAI2x contrast-to-noise fluid\/muscle was higher compared to CS (<jats:italic>p<\/jats:italic> \u2264 0.05), while no differences were found for other tissues. Signal-to-noise and contrast-to-noise were higher for CSAI3x compared to CS (<jats:italic>p<\/jats:italic> \u2264 0.05). The high - resolution axial T2-w sequence specifically improved the depiction of tendons and the tibial nerve (<jats:italic>p<\/jats:italic> \u2264 0.005).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Acquisition times can be reduced by 47% using CSAI compared to CS without decreasing diagnostic image quality. Reducing acquisition times by 63% is feasible but should be reserved for specific patients. The depiction of specific structures is improved using a high-resolution axial T2-w CSAI scan.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Key Points<\/jats:title>\n                <jats:p><jats:italic>\u2022 Prospective study showed that CSAI enables reduction in acquisition times by 47% without decreasing diagnostic image quality.<\/jats:italic><\/jats:p>\n                <jats:p><jats:italic>\u2022 Reducing acquisition times by 63% still produces images with an acceptable diagnostic accuracy but should be reserved for specific patients.<\/jats:italic><\/jats:p>\n                <jats:p><jats:italic>\u2022 CSAI may be implemented to scan at a higher resolution compared to standard CS images without increasing acquisition times.<\/jats:italic><\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00330-022-08919-9","type":"journal-article","created":{"date-parts":[[2022,6,25]],"date-time":"2022-06-25T05:07:54Z","timestamp":1656133674000},"page":"8376-8385","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":58,"title":["Deep learning\u2013based acceleration of Compressed Sense MR imaging of the ankle"],"prefix":"10.1007","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9140-0162","authenticated-orcid":false,"given":"Sarah C.","family":"Foreman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Neumann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessie","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norbert","family":"Harrasser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kilian","family":"Weiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes M.","family":"Peeters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios C.","family":"Karampinos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus R.","family":"Makowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra S.","family":"Gersing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Woertler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,6,25]]},"reference":[{"key":"8919_CR1","doi-asserted-by":"crossref","unstructured":"Rosenberg ZS, Beltran J, Bencardino JT (2000) From the RSNA Refresher Courses. 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