{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:16:45Z","timestamp":1792783005449,"version":"4.5.0"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T00:00:00Z","timestamp":1669766400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T00:00:00Z","timestamp":1669766400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST 109-2314-B-002-097-"],"award-info":[{"award-number":["MOST 109-2314-B-002-097-"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Taiwan University Hospita","award":["A1 project no. NTUH 111-A162"],"award-info":[{"award-number":["A1 project no. NTUH 111-A162"]}],"id":[{"id":"https:\/\/ror.org\/03nteze27","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Radiol"],"DOI":"10.1007\/s00330-022-09276-3","type":"journal-article","created":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T04:05:41Z","timestamp":1669781141000},"page":"2638-2646","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Efficacy of preoperative embolization for metastatic spinal tumor surgery using angiographic vascularity assessment"],"prefix":"10.1007","volume":"33","author":[{"given":"Yu-Cheng","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fon-Yih","family":"Tsuang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chung-Wei","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4327-7432","authenticated-orcid":false,"given":"Yen-Heng","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,11,30]]},"reference":[{"key":"9276_CR1","first-page":"i5","volume":"7","author":"JT Wewel","year":"2020","unstructured":"Wewel JT, O'Toole JE (2020) Epidemiology of spinal cord and column tumors. Neurooncol Pract 7:i5\u2013i9","journal-title":"Neurooncol Pract"},{"key":"9276_CR2","doi-asserted-by":"publisher","first-page":"e720","DOI":"10.1016\/S1470-2045(17)30612-5","volume":"18","author":"DE Spratt","year":"2017","unstructured":"Spratt DE, Beeler WH, de Moraes FY et al (2017) An integrated multidisciplinary algorithm for the management of spinal metastases: an International Spine Oncology Consortium report. Lancet Oncol 18:e720\u2013e730","journal-title":"Lancet Oncol"},{"key":"9276_CR3","doi-asserted-by":"publisher","first-page":"E256","DOI":"10.1097\/BSD.0000000000000911","volume":"33","author":"X Gao","year":"2020","unstructured":"Gao X, Fan T, He S et al (2020) A useful model for predicting intraoperative blood loss in metastatic spine tumor surgery. Clin Spine Surg 33:E256\u2013e262","journal-title":"Clin Spine Surg"},{"key":"9276_CR4","doi-asserted-by":"crossref","unstructured":"Luksanapruksa P, Buchowski JM, Tongsai S, Singhatanadgige W, Jennings JW (2018) Systematic review and meta-analysis of effectiveness of preoperative embolization in surgery for metastatic spine disease. J Neurointerv Surg 10:596","DOI":"10.1136\/neurintsurg-2017-013350"},{"key":"9276_CR5","doi-asserted-by":"publisher","first-page":"e745","DOI":"10.1016\/j.wneu.2021.06.062","volume":"152","author":"ZY Gao","year":"2021","unstructured":"Gao ZY, Zhang T, Zhang H, Pang CG, Xia Q (2021) Effectiveness of preoperative embolization in patients with spinal metastases: a systematic review and meta-analysis. World Neurosurg 152:e745\u2013e757","journal-title":"World Neurosurg"},{"key":"9276_CR6","doi-asserted-by":"publisher","unstructured":"Westbroek EM, Pennington Z, Ahmed AK et al (2020) Comparison of complete and near-complete endovascular embolization of hypervascular spine tumors with partial embolization. J Neurosurg Spine. https:\/\/doi.org\/10.3171\/2020.1.Spine191337:1-7","DOI":"10.3171\/2020.1.Spine191337:1-7"},{"key":"9276_CR7","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1258\/ar.2012.120314","volume":"53","author":"K Kobayashi","year":"2012","unstructured":"Kobayashi K, Ozkan E, Tam A, Ensor J, Wallace MJ, Gupta S (2012) Preoperative embolization of spinal tumors: variables affecting intraoperative blood loss after embolization. Acta Radiol 53:935\u2013942","journal-title":"Acta Radiol"},{"key":"9276_CR8","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1016\/j.wneu.2015.11.064","volume":"87","author":"CJ Griessenauer","year":"2016","unstructured":"Griessenauer CJ, Salem M, Hendrix P, Foreman PM, Ogilvy CS, Thomas AJ (2016) Preoperative embolization of spinal tumors: a systematic review and meta-analysis. World Neurosurg 87:362\u2013371","journal-title":"World Neurosurg"},{"key":"9276_CR9","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1097\/00007632-200102010-00016","volume":"26","author":"K Tomita","year":"2001","unstructured":"Tomita K, Kawahara N, Kobayashi T, Yoshida A, Murakami H, Akamaru T (2001) Surgical strategy for spinal metastases. Spine (Phila Pa 1976) 26:298\u2013306","journal-title":"Spine (Phila Pa 1976)"},{"key":"9276_CR10","doi-asserted-by":"publisher","first-page":"2186","DOI":"10.1097\/01.brs.0000180401.06919.a5","volume":"30","author":"Y Tokuhashi","year":"2005","unstructured":"Tokuhashi Y, Matsuzaki H, Oda H, Oshima M, Ryu J (2005) A revised scoring system for preoperative evaluation of metastatic spine tumor prognosis. Spine (Phila Pa 1976) 30:2186\u20132191","journal-title":"Spine (Phila Pa 1976)"},{"key":"9276_CR11","first-page":"155","volume":"12","author":"M Cappuccio","year":"2008","unstructured":"Cappuccio M, Gasbarrini A, Van Urk P, Bandiera S, Boriani S (2008) Spinal metastasis: a retrospective study validating the treatment algorithm. Eur Rev Med Pharmacol Sci 12:155\u2013160","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"9276_CR12","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1097\/BRS.0000000000003823","volume":"46","author":"N Kumar","year":"2021","unstructured":"Kumar N, Ramos MRD, Patel R et al (2021) The \u201cSpinal Metastasis Invasiveness Index\u201d: a novel scoring system to assess surgical invasiveness. Spine (Phila Pa 1976) 46:478\u2013485","journal-title":"Spine (Phila Pa 1976)"},{"key":"9276_CR13","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1016\/j.nic.2019.07.007","volume":"29","author":"P Gailloud","year":"2019","unstructured":"Gailloud P (2019) Spinal vascular anatomy. Neuroimaging Clin N Am 29:615\u2013633","journal-title":"Neuroimaging Clin N Am"},{"key":"9276_CR14","doi-asserted-by":"publisher","first-page":"E950","DOI":"10.1097\/BRS.0000000000000409","volume":"39","author":"JC Mazura","year":"2014","unstructured":"Mazura JC, Karimi S, Pauliah M et al (2014) Dynamic contrast-enhanced magnetic resonance perfusion compared with digital subtraction angiography for the evaluation of extradural spinal metastases: a pilot study. Spine (Phila Pa 1976) 39:E950\u2013E954","journal-title":"Spine (Phila Pa 1976)"},{"key":"9276_CR15","doi-asserted-by":"publisher","first-page":"920","DOI":"10.3174\/ajnr.A6023","volume":"40","author":"YC Huang","year":"2019","unstructured":"Huang YC, Tsuang FY, Lee CW, Wu CY, Lin YH (2019) Assessing vascularity of osseous spinal metastases with dual-energy CT-DSA: a pilot study compared with catheter angiography. AJNR Am J Neuroradiol 40:920\u2013925","journal-title":"AJNR Am J Neuroradiol"},{"key":"9276_CR16","doi-asserted-by":"publisher","unstructured":"Groot OQ, van Steijn NJ, Ogink PT et al (2022) Preoperative embolization in surgical treatment of spinal metastases originating from non-hypervascular primary tumors: a propensity score matched study using 495 patients. Spine J. https:\/\/doi.org\/10.1016\/j.spinee.2022.03.001","DOI":"10.1016\/j.spinee.2022.03.001"},{"key":"9276_CR17","doi-asserted-by":"publisher","first-page":"106","DOI":"10.3340\/jkns.2018.0073","volume":"62","author":"SL Yoo","year":"2019","unstructured":"Yoo SL, Kim YH, Park HY et al (2019) Clinical significance of preoperative embolization for non-hypervascular metastatic spine tumors. J Korean Neurosurg Soc 62:106\u2013113","journal-title":"J Korean Neurosurg Soc"},{"key":"9276_CR18","doi-asserted-by":"publisher","first-page":"951","DOI":"10.1007\/s10143-018-1003-8","volume":"42","author":"J Zhang","year":"2019","unstructured":"Zhang J, Kumar NS, Tan BWL, Shen L, Anil G (2019) Pre-operative embolisation of spinal tumours: neither neglect the neighbour nor blindly follow the gold standard. Neurosurg Rev 42:951\u2013959","journal-title":"Neurosurg Rev"},{"key":"9276_CR19","doi-asserted-by":"publisher","first-page":"597476","DOI":"10.3389\/fonc.2020.597476","volume":"10","author":"Y Gong","year":"2020","unstructured":"Gong Y, Wang C, Liu H, Liu X, Jiang L (2020) Only tumors angiographically identified as hypervascular exhibit lower intraoperative blood loss upon selective preoperative embolization of spinal metastases: systematic review and meta-analysis. Front Oncol 10:597476","journal-title":"Front Oncol"},{"key":"9276_CR20","doi-asserted-by":"publisher","first-page":"1530","DOI":"10.1097\/01.BRS.0000131420.32770.06","volume":"29","author":"K Nambu","year":"2004","unstructured":"Nambu K, Kawahara N, Kobayashi T, Murakami H, Ueda Y, Tomita K (2004) Interruption of the bilateral segmental arteries at several levels: influence on vertebral blood flow. Spine (Phila Pa 1976) 29:1530\u20131534","journal-title":"Spine (Phila Pa 1976)"},{"key":"9276_CR21","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.jocn.2017.05.021","volume":"43","author":"BWL Tan","year":"2017","unstructured":"Tan BWL, Zaw AS, Rajendran PC, Ruiz JN, Kumar N, Anil G (2017) Preoperative embolization in spinal tumour surgery: enhancing its effectiveness. J Clin Neurosci 43:108\u2013114","journal-title":"J Clin Neurosci"},{"key":"9276_CR22","doi-asserted-by":"publisher","first-page":"3962","DOI":"10.1007\/s00586-016-4494-4","volume":"25","author":"N Kumar","year":"2016","unstructured":"Kumar N, Tan B, Zaw AS et al (2016) The role of preoperative vascular embolization in surgery for metastatic spinal tumours. Eur Spine J 25:3962\u20133970","journal-title":"Eur Spine J"},{"key":"9276_CR23","doi-asserted-by":"publisher","first-page":"581","DOI":"10.5435\/JAAOS-D-14-00219","volume":"23","author":"MW Colman","year":"2015","unstructured":"Colman MW, Hornicek FJ, Schwab JH (2015) Spinal cord blood supply and its surgical implications. J Am Acad Orthop Surg 23:581\u2013591","journal-title":"J Am Acad Orthop Surg"},{"key":"9276_CR24","doi-asserted-by":"publisher","first-page":"E1187","DOI":"10.1097\/BRS.0b013e3181e215e5","volume":"35","author":"H Murakami","year":"2010","unstructured":"Murakami H, Kawahara N, Tomita K, Demura S, Kato S, Yoshioka K (2010) Does interruption of the artery of Adamkiewicz during total en bloc spondylectomy affect neurologic function? Spine (Phila Pa 1976) 35:E1187\u2013E1192","journal-title":"Spine (Phila Pa 1976)"},{"key":"9276_CR25","doi-asserted-by":"publisher","first-page":"4690","DOI":"10.1007\/s00330-020-07654-3","volume":"31","author":"K Premat","year":"2021","unstructured":"Premat K, Shotar E, Burns R et al (2021) Reliability and accuracy of time-resolved contrast-enhanced magnetic resonance angiography in hypervascular spinal metastases prior embolization. Eur Radiol 31:4690\u20134699","journal-title":"Eur Radiol"},{"key":"9276_CR26","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1302\/0301-620X.95B5.31270","volume":"95-b","author":"Y Chen","year":"2013","unstructured":"Chen Y, Tai BC, Nayak D et al (2013) Blood loss in spinal tumour surgery and surgery for metastatic spinal disease: a meta-analysis. Bone Joint J 95-b:683\u2013688","journal-title":"Bone Joint J"},{"key":"9276_CR27","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1148\/radiology.176.3.2389026","volume":"176","author":"FE Gellad","year":"1990","unstructured":"Gellad FE, Sadato N, Numaguchi Y, Levine AM (1990) Vascular metastatic lesions of the spine: preoperative embolization. Radiology 176:683\u2013686","journal-title":"Radiology"},{"key":"9276_CR28","doi-asserted-by":"publisher","first-page":"548","DOI":"10.3171\/jns.1990.73.4.0548","volume":"73","author":"N Sundaresan","year":"1990","unstructured":"Sundaresan N, Choi IS, Hughes JE, Sachdev VP, Berenstein A (1990) Treatment of spinal metastases from kidney cancer by presurgical embolization and resection. J Neurosurg 73:548\u2013554","journal-title":"J Neurosurg"},{"key":"9276_CR29","doi-asserted-by":"publisher","first-page":"2457","DOI":"10.1016\/j.clineuro.2013.09.033","volume":"115","author":"GM Ghobrial","year":"2013","unstructured":"Ghobrial GM, Chalouhi N, Harrop J et al (2013) Preoperative spinal tumor embolization: an institutional experience with Onyx. Clin Neurol Neurosurg 115:2457\u20132463","journal-title":"Clin Neurol Neurosurg"},{"key":"9276_CR30","doi-asserted-by":"publisher","first-page":"1813","DOI":"10.3171\/2015.5.JNS15124","volume":"124","author":"TR Ladner","year":"2016","unstructured":"Ladner TR, He L, Davis BJ, Yang GL, Wanna GB, Mocco J (2016) Initial experience with dual-lumen balloon catheter injection for preoperative Onyx embolization of skull base paragangliomas. J Neurosurg 124:1813\u20131819","journal-title":"J Neurosurg"},{"key":"9276_CR31","doi-asserted-by":"publisher","first-page":"E431","DOI":"10.1227\/01.NEU.0000223503.92392.CE","volume":"59","author":"CM Schirmer","year":"2006","unstructured":"Schirmer CM, Malek AM, Kwan ES, Hoit DA, Weller SJ (2006) Preoperative embolization of hypervascular spinal metastases using percutaneous direct injection with n-butyl cyanoacrylate: technical case report. Neurosurgery 59:E431\u2013E432 author reply E431-432","journal-title":"Neurosurgery"},{"key":"9276_CR32","doi-asserted-by":"publisher","first-page":"606","DOI":"10.3171\/2013.3.SPINE12832","volume":"18","author":"F Claren\u00e7on","year":"2013","unstructured":"Claren\u00e7on F, Di Maria F, Cormier E et al (2013) Onyx injection by direct puncture for the treatment of hypervascular spinal metastases close to the anterior spinal artery: initial experience. J Neurosurg Spine 18:606\u2013610","journal-title":"J Neurosurg Spine"},{"key":"9276_CR33","doi-asserted-by":"publisher","first-page":"1875","DOI":"10.3174\/ajnr.A3111","volume":"33","author":"J Chen","year":"2012","unstructured":"Chen J, Ethiati T, Gailloud P (2012) Flat panel catheter angiotomography of the spinal venous system: an enhanced venous phase for spinal digital subtraction angiography. AJNR Am J Neuroradiol 33:1875\u20131881","journal-title":"AJNR Am J Neuroradiol"},{"key":"9276_CR34","doi-asserted-by":"publisher","unstructured":"Raz E, Nossek E, Sahlein DH et al (2022) Principles, techniques and applications of high resolution cone beam CT angiography in the neuroangio suite. J Neurointerv Surg https:\/\/doi.org\/10.1136\/jnis-2022-018722:neurintsurg-2022-018722","DOI":"10.1136\/jnis-2022-018722:neurintsurg-2022-018722"}],"container-title":["European Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-022-09276-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00330-022-09276-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-022-09276-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,15]],"date-time":"2023-03-15T09:11:02Z","timestamp":1678871462000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00330-022-09276-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,30]]},"references-count":34,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,4]]}},"alternative-id":["9276"],"URL":"https:\/\/doi.org\/10.1007\/s00330-022-09276-3","relation":{},"ISSN":["1432-1084"],"issn-type":[{"value":"1432-1084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,30]]},"assertion":[{"value":"6 June 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 October 2022","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 October 2022","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 November 2022","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The scientific guarantor of this publication is Dr. Yen-Heng Lin.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Guarantor"}},{"value":"The authors of this manuscript declare no relationships with any companies whose products or services may be related to the subject matter of the article.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The statistical works had been reviewed by a biostatistician and a statistical analyst in the Center of Statistical Consultation and Research of the Department of Medical Research, National Taiwan University Hospital.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statistics and biometry"}},{"value":"Written informed consent was waived by the institutional review board.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The study was approved by the research ethics committee of the National Taiwan University Hospital. Approval number: 201810005RIND","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"\u2022 retrospective\u2022 observational\u2022 performed at one institution","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Methodology"}}]}}