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Two blinded radiologists jointly reviewed each examination for signs of bowel ischemia, abdominal organ infarct, mesenteric vessel size and regularity, and ancillary vascular findings. VCA administration (length and dosage), clinical and biochemical data, risk factors, and outcomes were retrieved from patients\u2019 medical records. Subgroup comparisons were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ninety patients were included (59 males, mean age 65\u00a0years); 40 (44.4%) had received VCAs before MDCT. Overall mortality was 32% (<jats:italic>n<\/jats:italic>\u2009=\u200929), with no significant difference between the two groups. In patients treated with VCAs, the calibre of the superior mesenteric artery (SMA) was smaller (<jats:italic>p<\/jats:italic>\u2009=\u20090.032), and vasoconstriction of its branches tended to be more important (<jats:italic>p<\/jats:italic>\u2009=\u20090.096) than in patients not treated with VCAs. The presence and extent of bowel ischemia did not significantly correlate with VCA administration, but abdominal organ infarcts tended to be more frequent (<jats:italic>p<\/jats:italic>\u2009=\u20090.005) and involved more organs (<jats:italic>p<\/jats:italic>\u2009=\u20090.088). The VCA group had lower mean arterial pressure (<jats:italic>p<\/jats:italic>\u2009=\u20090.006) and lower hemoglobin levels (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Several biomarkers of organ failure and inflammation, differed significantly with VCA use, proving worse clinical condition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>MDCT demonstrates more severe SMA vasoconstriction and tends to show increased abdominal organ infarcts after VCA administration in NOMI patients compared to NOMI patients not treated with VCAs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key Points<\/jats:title><jats:p><jats:italic>\u2022 In critically ill patients with NOMI, MDCT demonstrates VCA support via increased vasoconstriction of the main SMA and its branches.<\/jats:italic><\/jats:p><jats:p><jats:italic>\u2022 VCA administration in NOMI patients tends to contribute to the development of organ infarcts, as shown on MDCT.<\/jats:italic><\/jats:p><jats:p><jats:italic>\u2022 An important degree of vasoconstriction in NOMI patients may indicate insufficient resuscitation and, thus, help clinicians in further patient management.<\/jats:italic><\/jats:p><\/jats:sec>","DOI":"10.1007\/s00330-023-09415-4","type":"journal-article","created":{"date-parts":[[2023,1,24]],"date-time":"2023-01-24T07:48:18Z","timestamp":1674546498000},"page":"3627-3637","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["MDCT-findings in patients with non-occlusive mesenteric ischemia (NOMI): influence of vasoconstrictor agents"],"prefix":"10.1007","volume":"33","author":[{"given":"Antoine","family":"Topolsky","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Pantet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas","family":"Liaudet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Sempoux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alban","family":"Denys","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Fran\u00e7ois","family":"Knebel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2631-3032","authenticated-orcid":false,"given":"Sabine","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,1,24]]},"reference":[{"key":"9415_CR1","doi-asserted-by":"publisher","unstructured":"Kassahun WT, Schulz T, Richter O, Hauss J (2008) Unchanged high mortality rates from acute occlusive intestinal ischemia: six year review.\u00a0Langenbecks Arch Surg\u00a0393:163\u2013171. https:\/\/doi.org\/10.1007\/s00423-007-0263-5","DOI":"10.1007\/s00423-007-0263-5"},{"key":"9415_CR2","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1007\/s00330-016-4348-9","volume":"27","author":"MO Treyaud","year":"2017","unstructured":"Treyaud MO, Duran R, Zins M et al (2017) Clinical significance of pneumatosis intestinalis \u2013 correlation of MDCT-findings with treatment and outcome. 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