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Alara had no role in the study, and Dr. Smith-Bindman has not received funding from Alara Imaging. Other authors have no relationships with Alara and no conflicts of interests relevant to this article to disclose.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Multiple authors have significant statistical expertise, and no complex statistical methods were necessary for this paper.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statistics and biometry"}},{"value":"The UCSF Committee on Human Research provided a waiver of individual informed consent. Collaborating institutions obtained local Institutional Review Board approval or relied on the UCSF approval to contribute data to the Registry.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"Institutional Review Board approval was not required because the paper uses anonymized data.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Some study subjects or cohorts overlap with\u00a0several studies that use the same dose registry, but for different purposes, including:Chu PW, Yu S, Wang Y, et al Reference phantom selection in pediatric computed tomography using data from a large, multicenter registry. Pediatr Radiol. 2022 Mar;52(3):445\u2013452. . Epub 2021 Dec 6. PMID: 34866159; PMCID: PMC8857172.Smith-Bindman R, Chu P, Wang Y, et al Comparison of the effectiveness of single-component and multicomponent interventions for reducing radiation doses in patients undergoing computed tomography: a randomized clinical trial. JAMA Intern Med. 2020 May 1;180(5):666\u2013675. . PMID: 32227142; PMCID: PMC7105953.Smith-Bindman R, Wang Y, Chu P, et al International variation in radiation dose for computed tomography examinations: prospective cohort study. BMJ. 2019 Jan 2;364:k4931. . PMID: 30602590; PMCID: PMC6314083.The CT data derive from the UCSF International CT Dose Registry, some parts of which have been used in prior publications, including approximately 1 million CTs in a randomized trial to assess whether participation in a learning collaborative results in meaningful reduction in radiation doses.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Study subjects or cohorts overlap"}},{"value":"\u2022 prospective\u2022 observational\u2022 multicenter study","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Methodology"}}]}}