{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:19:46Z","timestamp":1786979986596,"version":"build-2736575974"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2024,2,17]],"date-time":"2024-02-17T00:00:00Z","timestamp":1708128000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,2,17]],"date-time":"2024-02-17T00:00:00Z","timestamp":1708128000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["DE 1361\/14-1"],"award-info":[{"award-number":["DE 1361\/14-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Radiol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Because there is evidence for a clinical benefit of using coronary computed tomography (CT) angiography instead of invasive coronary angiography (ICA) in patients with suspected coronary artery disease (CAD), we ascertained if patient satisfaction could represent an important barrier to implementation of coronary CT in clinical practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>A total of 329 patients with suspected CAD and clinical indication for ICA were randomly assigned to undergo either CT or ICA for guiding treatment. Satisfaction for both groups was assessed by patient questionnaire completed twice, \u226524 h after CT or ICA, and at follow-up after a median of 3.7 years. Assessment included preparation, concern, comfort, helplessness, pain, willingness to undergo tests again, overall satisfaction, and preference. Pearson\u2019s chi-square test and Wilcoxon rank-sum test were used.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall, 91% of patients undergoing CT (152\/167) and 86% undergoing ICA completed assessment (140\/162,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.19). Patients reported being significantly better prepared for CT, less concerned about the test, and felt less helpless than during ICA (all:\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      &lt; 0.001). Subjective pain (horizontal nonmarked visual analogue scale) was significantly lower for CT (6.9 \u00b1 14.7) than for ICA (17.1 \u00b1 22.7;\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      &lt; 0.001). At follow-up, significantly more patients in the CT group reported very good satisfaction with communication of findings compared with the ICA group (\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      &lt; 0.001) and 92% would recommend the institution to someone referred for the same examination.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Results from our single-center randomized study show very good satisfaction with coronary CT compared to ICA. Thus, superior acceptance of CT should be considered in shared decision-making.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical relevance statement<\/jats:title>\n                    <jats:p>This evaluation of patient satisfaction in a randomized study shows that patients\u2019 preference is in line with the clinical benefit provided by CT and also suggests to prefer a CT-first strategy in suspected coronary artery disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key Points<\/jats:title>\n                    <jats:p>\n                      \u2022\n                      <jats:italic>Subjective pain was significantly lower for coronary CT angiography than for invasive coronary angiography and patients felt better prepared and less concerned about CT.<\/jats:italic>\n                    <\/jats:p>\n                    <jats:p>\n                      \u2022\n                      <jats:italic>Patients were overall more satisfied with coronary CT angiography than invasive coronary angiography in a randomized controlled trial.<\/jats:italic>\n                    <\/jats:p>\n                    <jats:p>\n                      \u2022\n                      <jats:italic>After a median follow-up of 3.7 years, more patients in the CT group indicated very good satisfaction with the communication of findings and with the examination itself.<\/jats:italic>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00330-023-10554-x","type":"journal-article","created":{"date-parts":[[2024,2,17]],"date-time":"2024-02-17T09:02:51Z","timestamp":1708160571000},"page":"5644-5653","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Patient satisfaction with coronary CT angiography versus invasive coronary angiography: results of a single-center randomized trial"],"prefix":"10.1007","volume":"34","author":[{"given":"Maria","family":"Bosserdt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viktoria","family":"Wieske","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabian","family":"Knebel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud M. A.","family":"Mohamed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Feger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4402-2733","authenticated-orcid":false,"given":"Marc","family":"Dewey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Sch\u00f6nenberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,2,17]]},"reference":[{"key":"10554_CR1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz425","author":"J Knuuti","year":"2019","unstructured":"Knuuti J, Wijns W, Saraste A et al (2019) 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes. Eur Heart J. https:\/\/doi.org\/10.1093\/eurheartj\/ehz425","journal-title":"Eur Heart J"},{"key":"10554_CR2","unstructured":"Haase R, ...., Dewey M (2019) COME-CCT investigators. Diagnosis of obstructive coronary artery disease using computed tomography angiography in patients with stable chest pain: meta-analysis of individual patient data. BMJ 365:l1945"},{"key":"10554_CR3","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy267","author":"J Knuuti","year":"2018","unstructured":"Knuuti J, Ballo H, Juarez-Orozco LE et al (2018) The performance of non-invasive tests to rule-in and rule-out significant coronary artery stenosis in patients with stable angina: a meta-analysis focused on post-test disease probability. Eur Heart J. https:\/\/doi.org\/10.1093\/eurheartj\/ehy267","journal-title":"Eur Heart J"},{"key":"10554_CR4","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1148\/radiol.2019182061","volume":"292","author":"KM Johnson","year":"2019","unstructured":"Johnson KM, Johnson HE, Zhao Y, Dowe DA, Staib LH (2019) Scoring of coronary artery disease characteristics on coronary CT angiograms by using machine learning. Radiology 292:354\u2013362","journal-title":"Radiology"},{"key":"10554_CR5","doi-asserted-by":"publisher","first-page":"e246","DOI":"10.1371\/journal.pone.0000246","volume":"2","author":"E Sch\u00f6nenberger","year":"2007","unstructured":"Sch\u00f6nenberger E, Schnapauff D, Teige F, Laule M, Hamm B, Dewey M (2007) Patient acceptance of noninvasive and invasive coronary angiography. PLoS One 2:e246","journal-title":"PLoS One"},{"key":"10554_CR6","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1148\/radiol.2019181409","volume":"291","author":"A Minhas","year":"2019","unstructured":"Minhas A, Dewey M, Vavere AL et al (2019) Patient preferences for coronary CT angiography with stress perfusion, SPECT, or invasive coronary angiography. Radiology 291:340\u2013348","journal-title":"Radiology"},{"key":"10554_CR7","doi-asserted-by":"publisher","first-page":"174","DOI":"10.7326\/M14-2948","volume":"163","author":"JM Levsky","year":"2015","unstructured":"Levsky JM, Spevack DM, Travin MI et al (2015) Coronary computed tomography angiography versus radionuclide myocardial perfusion imaging in patients with chest pain admitted to telemetry: a randomized trial. Ann Intern Med 163:174\u2013183","journal-title":"Ann Intern Med"},{"key":"10554_CR8","doi-asserted-by":"publisher","first-page":"i5441","DOI":"10.1136\/bmj.i5441","volume":"355","author":"M Dewey","year":"2016","unstructured":"Dewey M, Rief M, Martus P et al (2016) Evaluation of computed tomography in patients with atypical angina or chest pain clinically referred for invasive coronary angiography: randomised controlled trial. BMJ 355:i5441","journal-title":"BMJ"},{"key":"10554_CR9","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1148\/radiol.2019182220","volume":"292","author":"E Schonenberger","year":"2019","unstructured":"Schonenberger E, Martus P, Bosserdt M et al (2019) Kidney injury after intravenous versus intra-arterial contrast agent in patients suspected of having coronary artery disease: a randomized trial. Radiology 292:664\u2013672","journal-title":"Radiology"},{"key":"10554_CR10","first-page":"e071133","volume":"379","author":"K Kofoed","year":"2022","unstructured":"Discharge Trial Group, Kofoed K, Bosserdt M et al (2022) Comparative effectiveness of initial computed tomography and invasive coronary angiography in women and men with stable chest pain and suspected coronary artery disease: multicentre randomised trial. BMJ 379:e071133","journal-title":"BMJ"},{"key":"10554_CR11","doi-asserted-by":"publisher","first-page":"1591","DOI":"10.1056\/NEJMoa2200963","volume":"386","author":"P Maurovich-Horvat","year":"2022","unstructured":"DISCHARGE Trial Group, Maurovich-Horvat P, Bosserdt M et al (2022) CT or invasive coronary angiography for stable chest pain. N Engl J Med 386:1591\u20131602","journal-title":"N Engl J Med"},{"key":"10554_CR12","doi-asserted-by":"publisher","unstructured":"Feger S, Rief M, Zimmermann E et al (2015) Patient satisfaction with coronary CT angiography, myocardial CT perfusion, myocardial perfusion MRI, SPECT myocardial perfusion imaging and conventional coronary angiography. Eur Radiol. https:\/\/doi.org\/10.1007\/s00330-015-3604-8","DOI":"10.1007\/s00330-015-3604-8"},{"key":"10554_CR13","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1148\/radiol.2451061244","volume":"245","author":"J Florie","year":"2007","unstructured":"Florie J, Birnie E, van Gelder RE et al (2007) MR colonography with limited bowel preparation: patient acceptance compared with that of full-preparation colonoscopy. Radiology 245:150\u2013159","journal-title":"Radiology"},{"key":"10554_CR14","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1148\/radiol.2331031208","volume":"233","author":"RE van Gelder","year":"2004","unstructured":"van Gelder RE, Birnie E, Florie J et al (2004) CT colonography and colonoscopy: assessment of patient preference in a 5-week follow-up study. Radiology 233:328\u2013337","journal-title":"Radiology"},{"key":"10554_CR15","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1148\/radiol.2241011222","volume":"224","author":"PA Lefere","year":"2002","unstructured":"Lefere PA, Gryspeerdt SS, Dewyspelaere J, Baekelandt M, Van Holsbeeck BG (2002) Dietary fecal tagging as a cleansing method before CT colonography: initial results polyp detection and patient acceptance. Radiology 224:393\u2013403","journal-title":"Radiology"},{"key":"10554_CR16","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1148\/radiol.2383041308","volume":"239","author":"ME Zalis","year":"2006","unstructured":"Zalis ME, Perumpillichira JJ, Magee C, Kohlberg G, Hahn PF (2006) Tagging-based, electronically cleansed CT colonography: evaluation of patient comfort and image readability. Radiology 239:149\u2013159","journal-title":"Radiology"},{"key":"10554_CR17","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1148\/radiol.12111523","volume":"263","author":"C von Wagner","year":"2012","unstructured":"von Wagner C, Ghanouni A, Halligan S et al (2012) Patient acceptability and psychologic consequences of CT colonography compared with those of colonoscopy: results from a multicenter randomized controlled trial of symptomatic patients. Radiology 263:723\u2013731","journal-title":"Radiology"},{"key":"10554_CR18","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1148\/radiol.2017162056","volume":"285","author":"JL Kemp","year":"2017","unstructured":"Kemp JL, Mahoney MC, Mathews VP, Wintermark M, Yee J, Brown SD (2017) Patient-centered radiology: where are we, where do we want to be, and how do we get there? Radiology 285:601\u2013608","journal-title":"Radiology"},{"key":"10554_CR19","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1148\/rg.2020190164","volume":"40","author":"A Canan","year":"2020","unstructured":"Canan A, Ranganath P, Goerne H, Abbara S, Landeras L, Rajiah P (2020) CAD-RADS: pushing the limits. Radiographics 40:629\u2013652","journal-title":"Radiographics"},{"key":"10554_CR20","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1148\/radiol.2019182307","volume":"291","author":"N Kapoor","year":"2019","unstructured":"Kapoor N, Yan Z, Wang A et al (2019) Improving patient experience in radiology: impact of a multifaceted intervention on national ranking. Radiology 291:102\u2013109","journal-title":"Radiology"},{"key":"10554_CR21","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.jacr.2013.07.016","volume":"11","author":"GW Boland","year":"2014","unstructured":"Boland GW, Duszak R Jr, McGinty G, Allen B Jr (2014) Delivery of appropriateness, quality, safety, efficiency and patient satisfaction. J Am Coll Radiol 11:7\u201311","journal-title":"J Am Coll Radiol"},{"key":"10554_CR22","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1148\/radiol.2017162187","volume":"283","author":"GD Rubin","year":"2017","unstructured":"Rubin GD, McNeil BJ, Palko A et al (2017) External factors that influence the practice of radiology: Proceedings of the International Society for Strategic Studies in Radiology Meeting. Radiology 283:845\u2013853","journal-title":"Radiology"},{"key":"10554_CR23","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1148\/radiol.2017170592","volume":"287","author":"JK Pahade","year":"2018","unstructured":"Pahade JK, Trout AT, Zhang B et al (2018) What patients want to know about imaging examinations: a multiinstitutional U.S. survey in adult and pediatric teaching hospitals on patient preferences for receiving information before radiologic examinations. Radiology 287:554\u2013562","journal-title":"Radiology"},{"key":"10554_CR24","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1093\/eurheartj\/ehz425","volume":"41","author":"J Knuuti","year":"2020","unstructured":"Knuuti J, Wijns W, Saraste A et al (2020) 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes. Eur Heart J 41:407\u2013477","journal-title":"Eur Heart J"},{"key":"10554_CR25","doi-asserted-by":"publisher","first-page":"e187","DOI":"10.1016\/j.jacc.2021.07.053","volume":"78","author":"M Gulati","year":"2021","unstructured":"Gulati M, Levy PD, Mukherjee D et al (2021) 2021 AHA\/ACC\/ASE\/CHEST\/SAEM\/SCCT\/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: A Report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines. J Am Coll Cardiol 78:e187\u2013e285","journal-title":"J Am Coll Cardiol"}],"container-title":["European Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-023-10554-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00330-023-10554-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-023-10554-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T08:09:58Z","timestamp":1725005398000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00330-023-10554-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,17]]},"references-count":25,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2024,9]]}},"alternative-id":["10554"],"URL":"https:\/\/doi.org\/10.1007\/s00330-023-10554-x","relation":{},"ISSN":["1432-1084"],"issn-type":[{"value":"1432-1084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,17]]},"assertion":[{"value":"9 August 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 November 2023","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 December 2023","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 February 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The scientific guarantor of this publication is Prof. Dr. Marc Dewey.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Guarantor"}},{"value":"MB, VW, MM, SF, and MD report grant support from the FP7 Program of the European Commission for the randomized multicentre DISCHARGE trial (603266-2, HEALTH-2012.2.4.-2). MD received grant support from German Research Foundation (DFG) in the Heisenberg Program (DE 1361\/14-1, DFG project number: 213705389), graduate program on quantitative biomedical imaging (BIOQIC, GRK 2260\/1, DFG project number: 289347353) for fractal analysis of myocardial perfusion (DE 1361\/18-1, DFG project number: 392304398), the DFG Priority Programme Radiomics (DFG project number: 402688427) for the investigation of coronary plaque and coronary flow (DE 1361\/19-1 [DFG project number: 428222922] and DE 1361\/20-1 [DFG project number: 428223139] in SPP 2177\/1), the GUIDE-IT project on data sharing of medical imaging trials (DE 1361\/24-1 [DFG project number: 495697118]), the Quantitative Cardiovascular Imaging (QCI) meeting (DE 1361\/22-1), and the Future of Medical Imaging meeting (DE 1361\/28-1). He also received funding from the Berlin University Alliance (GC_SC_PC 27) and from the Digital Health Accelerator of the Berlin Institute of Health. MD reported patent on fractal analysis of perfusion imaging (jointly with Florian Michallek, on dynamic perfusion analysis using fractal analysis (PCT\/EP2016\/071551 and USPTO 2021 10,991,109 approved)). MD is European Society of Radiology (ESR) Publications Chair (2022-2025); and the opinions expressed in this article are the author\u2019s own and do not represent the view of ESR. Per the guiding principles of ESR, the work as Publications Chair is on a voluntary basis and only remuneration of travel expenses occurs. He is also the editor of cardiac CT, published by Springer Nature, and offers hands-on courses on CT imaging (\n                      \n                      ). All other authors have nothing to disclose.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"MB and MM have significant statistical expertise.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statistics and biometry"}},{"value":"Written informed consent was obtained from all subjects (patients) in this study.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"This study was approved by the local research ethics committee of Charit\u00e9 (EA-1-080-08) and the German Federal Office for Radiation Protection (Z5-22462\/2-2008-048).","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The study cohort was reported in the CAD-Man main study report (\n                      \n                      ).","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Study subjects or cohorts overlap"}},{"value":"\u2022 Prospective\u2022 Randomized controlled trial\u2022 Performed at one institution","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Methodology"}}]}}