{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T05:17:35Z","timestamp":1791523055896,"version":"4.3.4"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2024,3,22]],"date-time":"2024-03-22T00:00:00Z","timestamp":1711065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,3,22]],"date-time":"2024-03-22T00:00:00Z","timestamp":1711065600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82272740"],"award-info":[{"award-number":["82272740"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Sun Yat-Sen University Clinical Research 5010 Program","award":["2020-FXY-406"],"award-info":[{"award-number":["2020-FXY-406"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Radiol"],"DOI":"10.1007\/s00330-024-10678-8","type":"journal-article","created":{"date-parts":[[2024,3,22]],"date-time":"2024-03-22T02:42:16Z","timestamp":1711075336000},"page":"6831-6842","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Radiomics-based nomogram guides adaptive de-intensification in locoregionally advanced nasopharyngeal carcinoma following induction chemotherapy"],"prefix":"10.1007","volume":"34","author":[{"given":"Shun-Xin","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Qiao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao-Jiang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Jie","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Jie","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Ming","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan-Feng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Zhi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1027-071X","authenticated-orcid":false,"given":"Yan-Ping","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,22]]},"reference":[{"key":"10678_CR1","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/S0140-6736(19)30956-0","volume":"394","author":"YP Chen","year":"2019","unstructured":"Chen YP, Chan ATC, Le QT, Blanchard P, Sun Y, Ma J (2019) Nasopharyngeal carcinoma. Lancet 394:64\u201380","journal-title":"Lancet"},{"key":"10678_CR2","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1016\/j.ijrobp.2008.07.062","volume":"73","author":"YP Mao","year":"2009","unstructured":"Mao YP, Xie FY, Liu LZ et al (2009) Re-evaluation of 6th edition of AJCC staging system for nasopharyngeal carcinoma and proposed improvement based on magnetic resonance imaging. Int J Radiat Oncol Biol Phys 73:1326\u20131334","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10678_CR3","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1200\/JCO.1998.16.4.1310","volume":"16","author":"M Al-Sarraf","year":"1998","unstructured":"Al-Sarraf M, LeBlanc M, Giri PG et al (1998) Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: phase III randomized intergroup study 0099. J Clin Oncol 16:1310\u20131317","journal-title":"J Clin Oncol"},{"key":"10678_CR4","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1200\/JCO.2003.06.158","volume":"21","author":"JC Lin","year":"2003","unstructured":"Lin JC, Jan JS, Hsu CY, Liang WM, Jiang RS, Wang WY (2003) Phase III study of concurrent chemoradiotherapy versus radiotherapy alone for advanced nasopharyngeal carcinoma: positive effect on overall and progression-free survival. J Clin Oncol 21:631\u2013637","journal-title":"J Clin Oncol"},{"key":"10678_CR5","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.ijrobp.2005.06.037","volume":"64","author":"B Baujat","year":"2006","unstructured":"Baujat B, Audry H, Bourhis J et al (2006) Chemotherapy in locally advanced nasopharyngeal carcinoma: an individual patient data meta-analysis of eight randomized trials and 1753 patients. Int J Radiat Oncol Biol Phys 64:47\u201356","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10678_CR6","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/S1470-2045(15)70126-9","volume":"16","author":"P Blanchard","year":"2015","unstructured":"Blanchard P, Lee A, Marguet S et al (2015) Chemotherapy and radiotherapy in nasopharyngeal carcinoma: an update of the MAC-NPC meta-analysis. Lancet Oncol 16:645\u2013655","journal-title":"Lancet Oncol"},{"key":"10678_CR7","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.ijrobp.2019.06.2549","volume":"105","author":"XS Sun","year":"2019","unstructured":"Sun XS, Liu SL, Luo MJ et al (2019) The association between the development of radiation therapy, image technology, and chemotherapy, and the survival of patients with nasopharyngeal carcinoma: a cohort study from 1990 to 2012. Int J Radiat Oncol Biol Phys 105:581\u2013590","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10678_CR8","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1186\/s12885-015-1768-x","volume":"15","author":"WF Li","year":"2015","unstructured":"Li WF, Li YQ, Chen L et al (2015) Propensity-matched analysis of three different chemotherapy sequences in patients with locoregionally advanced nasopharyngeal carcinoma treated using intensity-modulated radiotherapy. BMC Cancer 15:810","journal-title":"BMC Cancer"},{"key":"10678_CR9","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1186\/s13014-018-1092-0","volume":"13","author":"L Liu","year":"2018","unstructured":"Liu L, Fei Z, Chen M et al (2018) Induction chemotherapy plus concurrent chemoradiotherapy versus induction chemotherapy plus volumetric modulated arc therapy alone in the treatment of stage II-IVB nasopharyngeal carcinoma patients: a retrospective controlled study. Radiat Oncol 13:148","journal-title":"Radiat Oncol"},{"key":"10678_CR10","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.1038\/s41598-020-59470-w","volume":"10","author":"F Wang","year":"2020","unstructured":"Wang F, Jiang C, Wang L et al (2020) Influence of concurrent chemotherapy on locoregionally advanced nasopharyngeal carcinoma treated with neoadjuvant chemotherapy plus intensity-modulated radiotherapy: a retrospective matched analysis. Sci Rep 10:2489","journal-title":"Sci Rep"},{"key":"10678_CR11","doi-asserted-by":"crossref","first-page":"104925","DOI":"10.1016\/j.oraloncology.2020.104925","volume":"111","author":"Q Wang","year":"2020","unstructured":"Wang Q, Xu G, Xia Y et al (2020) Comparison of induction chemotherapy plus concurrent chemoradiotherapy and induction chemotherapy plus radiotherapy in locally advanced nasopharyngeal carcinoma. Oral Oncol 111:104925","journal-title":"Oral Oncol"},{"key":"10678_CR12","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1007\/s00432-019-02925-z","volume":"145","author":"Z Wei","year":"2019","unstructured":"Wei Z, Zhang Z, Luo J, Li N, Peng X (2019) Induction chemotherapy plus IMRT alone versus induction chemotherapy plus IMRT-based concurrent chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma: a retrospective cohort study. J Cancer Res Clin Oncol 145:1857\u20131864","journal-title":"J Cancer Res Clin Oncol"},{"key":"10678_CR13","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1093\/jnci\/djq258","volume":"102","author":"AW Lee","year":"2010","unstructured":"Lee AW, Tung SY, Chua DT et al (2010) Randomized trial of radiotherapy plus concurrent-adjuvant chemotherapy vs radiotherapy alone for regionally advanced nasopharyngeal carcinoma. J Natl Cancer Inst 102:1188\u20131198","journal-title":"J Natl Cancer Inst"},{"key":"10678_CR14","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.ejca.2010.10.026","volume":"47","author":"AW Lee","year":"2011","unstructured":"Lee AW, Tung SY, Ngan RK et al (2011) Factors contributing to the efficacy of concurrent-adjuvant chemotherapy for locoregionally advanced nasopharyngeal carcinoma: combined analyses of NPC-9901 and NPC-9902 Trials. Eur J Cancer 47:656\u2013666","journal-title":"Eur J Cancer"},{"key":"10678_CR15","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1093\/annonc\/mdw051","volume":"27","author":"VM Villaflor","year":"2016","unstructured":"Villaflor VM, Melotek JM, Karrison TG et al (2016) Response-adapted volume de-escalation (RAVD) in locally advanced head and neck cancer. Ann Oncol 27:908\u2013913","journal-title":"Ann Oncol"},{"key":"10678_CR16","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1200\/JCO.2016.68.3300","volume":"35","author":"S Marur","year":"2017","unstructured":"Marur S, Li S, Cmelak AJ et al (2017) E1308: phase II trial of induction chemotherapy followed by reduced-dose radiation and weekly cetuximab in patients with HPV-associated resectable squamous cell carcinoma of the oropharynx- ECOG-ACRIN Cancer Research Group. J Clin Oncol 35:490\u2013497","journal-title":"J Clin Oncol"},{"key":"10678_CR17","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1093\/annonc\/mdy522","volume":"30","author":"TY Seiwert","year":"2019","unstructured":"Seiwert TY, Foster CC, Blair EA et al (2019) OPTIMA: a phase II dose and volume de-escalation trial for human papillomavirus-positive oropharyngeal cancer. Ann Oncol 30:297\u2013302","journal-title":"Ann Oncol"},{"key":"10678_CR18","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.radonc.2020.10.005","volume":"155","author":"WJ Luo","year":"2021","unstructured":"Luo WJ, Zou WQ, Liang SB et al (2021) Combining tumor response and personalized risk assessment: potential for adaptation of concurrent chemotherapy in locoregionally advanced nasopharyngeal carcinoma in the intensity-modulated radiotherapy era. Radiother Oncol 155:56\u201364","journal-title":"Radiother Oncol"},{"key":"10678_CR19","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.ejca.2008.10.026","volume":"45","author":"EA Eisenhauer","year":"2009","unstructured":"Eisenhauer EA, Therasse P, Bogaerts J et al (2009) New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer 45:228\u2013247","journal-title":"Eur J Cancer"},{"key":"10678_CR20","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.3390\/cancers11111632","volume":"11","author":"FP Chen","year":"2019","unstructured":"Chen FP, Wen DW, Li F et al (2019) The role of post-neoadjuvant chemotherapy tumor volume for prognostication and treatment guidance in loco-regionally advanced nasopharyngeal carcinoma. Cancers (Basel) 11:1632","journal-title":"Cancers (Basel)"},{"key":"10678_CR21","doi-asserted-by":"crossref","first-page":"4442","DOI":"10.1200\/JCO.2004.07.960","volume":"22","author":"MJ Ratain","year":"2004","unstructured":"Ratain MJ, Eckhardt SG (2004) Phase II studies of modern drugs directed against new targets: if you are fazed, too, then resist RECIST. J Clin Oncol 22:4442\u20134445","journal-title":"J Clin Oncol"},{"key":"10678_CR22","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1093\/annonc\/mdx034","volume":"28","author":"EJ Limkin","year":"2017","unstructured":"Limkin EJ, Sun R, Dercle L et al (2017) Promises and challenges for the implementation of computational medical imaging (radiomics) in oncology. Ann Oncol 28:1191\u20131206","journal-title":"Ann Oncol"},{"key":"10678_CR23","doi-asserted-by":"crossref","first-page":"20170926","DOI":"10.1259\/bjr.20170926","volume":"91","author":"SA Keek","year":"2018","unstructured":"Keek SA, Leijenaar RT, Jochems A, Woodruff HC (2018) A review on radiomics and the future of theranostics for patient selection in precision medicine. Br J Radiol 91:20170926","journal-title":"Br J Radiol"},{"key":"10678_CR24","doi-asserted-by":"crossref","first-page":"20190948","DOI":"10.1259\/bjr.20190948","volume":"93","author":"W Rogers","year":"2020","unstructured":"Rogers W, Thulasi Seetha S, Refaee TAG et al (2020) Radiomics: from qualitative to quantitative imaging. Br J Radiol 93:20190948","journal-title":"Br J Radiol"},{"key":"10678_CR25","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1038\/nrclinonc.2017.141","volume":"14","author":"P Lambin","year":"2017","unstructured":"Lambin P, Leijenaar RTH, Deist TM et al (2017) Radiomics: the bridge between medical imaging and personalized medicine. Nat Rev Clin Oncol 14:749\u2013762","journal-title":"Nat Rev Clin Oncol"},{"key":"10678_CR26","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1148\/radiol.13122697","volume":"269","author":"RA Gatenby","year":"2013","unstructured":"Gatenby RA, Grove O, Gillies RJ (2013) Quantitative imaging in cancer evolution and ecology. Radiology 269:8\u201315","journal-title":"Radiology"},{"issue":"2","key":"10678_CR27","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1148\/radiol.2016151908","volume":"282","author":"IM Blazic","year":"2017","unstructured":"Blazic IM, Lilic GB, Gajic MM (2017) Quantitative assessment of rectal cancer response to neoadjuvant combined chemotherapy and radiation therapy: comparison of three methods of positioning region of interest for ADC measurements at diffusion-weighted MR imaging. Radiology 282(2):418\u2013428","journal-title":"Radiology"},{"key":"10678_CR28","doi-asserted-by":"crossref","first-page":"S95","DOI":"10.1016\/j.acra.2020.10.026","volume":"1","author":"L Wan","year":"2021","unstructured":"Wan L, Peng W, Zou S et al (2021) MRI-based delta-radiomics are predictive of pathological complete response after neoadjuvant chemoradiotherapy in locally advanced rectal cancer. Acad Radiol Suppl 1:S95\u2013S104","journal-title":"Acad Radiol Suppl"},{"key":"10678_CR29","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jcm.2016.02.012","volume":"15","author":"TK Koo","year":"2016","unstructured":"Koo TK, Li MY (2016) A guideline of selecting and reporting intraclass correlation coefficients for reliability research. J Chiropr Med 15:155\u2013163","journal-title":"J Chiropr Med"},{"key":"10678_CR30","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/(SICI)1097-0258(19960229)15:4<361::AID-SIM168>3.0.CO;2-4","volume":"15","author":"FE Harrell Jr","year":"1996","unstructured":"Harrell FE Jr, Lee KL, Mark DB (1996) Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Stat Med 15:361\u2013387","journal-title":"Stat Med"},{"key":"10678_CR31","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1093\/biostatistics\/kxs021","volume":"14","author":"P Saha-Chaudhuri","year":"2013","unstructured":"Saha-Chaudhuri P, Heagerty PJ (2013) Non-parametric estimation of a time-dependent predictive accuracy curve. Biostatistics 14:42\u201359","journal-title":"Biostatistics"},{"key":"10678_CR32","doi-asserted-by":"crossref","first-page":"499","DOI":"10.2307\/2531021","volume":"39","author":"DA Schoenfeld","year":"1983","unstructured":"Schoenfeld DA (1983) Sample-size formula for the proportional hazards regression model. Biometrics 39:499\u2013503","journal-title":"Biometrics"},{"key":"10678_CR33","unstructured":"National Comprehensive Cancer Network (NCCN) (2022) Clinical Practice Guidelines in Oncology. Version 1"},{"key":"10678_CR34","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1002\/1097-0142(19840901)54:5<811::AID-CNCR2820540508>3.0.CO;2-E","volume":"54","author":"JF Ensley","year":"1984","unstructured":"Ensley JF, Jacobs JR, Weaver A et al (1984) Correlation between response to cisplatinum-combination chemotherapy and subsequent radiotherapy in previously untreated patients with advanced squamous cell cancers of the head and neck. Cancer 54:811\u2013814","journal-title":"Cancer"},{"key":"10678_CR35","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1200\/JCO.2005.01.2047","volume":"24","author":"S Urba","year":"2006","unstructured":"Urba S, Wolf G, Eisbruch A et al (2006) Single-cycle induction chemotherapy selects patients with advanced laryngeal cancer for combined chemoradiation: a new treatment paradigm. J Clin Oncol 24:593\u2013598","journal-title":"J Clin Oncol"},{"key":"10678_CR36","doi-asserted-by":"crossref","first-page":"3138","DOI":"10.1200\/JCO.2007.12.7597","volume":"26","author":"FP Worden","year":"2008","unstructured":"Worden FP, Kumar B, Lee JS et al (2008) Chemoselection as a strategy for organ preservation in advanced oropharynx cancer: response and survival positively associated with HPV16 copy number. J Clin Oncol 26:3138\u20133146","journal-title":"J Clin Oncol"},{"key":"10678_CR37","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/s40364-021-00306-8","volume":"9","author":"CC Ko","year":"2021","unstructured":"Ko CC, Yeh LR, Kuo YT, Chen JH (2021) Imaging biomarkers for evaluating tumor response: RECIST and beyond. Biomark Res 9:52","journal-title":"Biomark Res"},{"key":"10678_CR38","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.radonc.2021.08.023","volume":"164","author":"JC Peeken","year":"2021","unstructured":"Peeken JC, Asadpour R, Specht K et al (2021) MRI-based delta-radiomics predicts pathologic complete response in high-grade soft-tissue sarcoma patients treated with neoadjuvant therapy. Radiother Oncol 164:73\u201382","journal-title":"Radiother Oncol"},{"key":"10678_CR39","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/S0140-6736(21)01123-5","volume":"398","author":"YP Chen","year":"2021","unstructured":"Chen YP, Liu X, Zhou Q et al (2021) Metronomic capecitabine as adjuvant therapy in locoregionally advanced nasopharyngeal carcinoma: a multicentre, open-label, parallel-group, randomised, controlled, phase 3 trial. Lancet 398:303\u2013313","journal-title":"Lancet"},{"issue":"6","key":"10678_CR40","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/nrd3455","volume":"10","author":"P Carmeliet","year":"2011","unstructured":"Carmeliet P, Jain RK (2011) Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases. Nat Rev Drug Discov 10(6):417\u2013427","journal-title":"Nat Rev Drug Discov"},{"issue":"7","key":"10678_CR41","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1007\/s11547-023-01650-5","volume":"128","author":"X Teng","year":"2023","unstructured":"Teng X, Zhang J, Han X (2023) Explainable machine learning via intra-tumoral radiomics feature mapping for patient stratification in adjuvant chemotherapy for locoregionally advanced nasopharyngeal carcinoma. Radiol Med 128(7):828\u2013838","journal-title":"Radiol Med"},{"key":"10678_CR42","doi-asserted-by":"crossref","first-page":"2313","DOI":"10.1002\/ijc.32021","volume":"144","author":"Y Zhang","year":"2019","unstructured":"Zhang Y, Tang LL, Li YQ, Liu X, Liu Q, Ma J (2019) Spontaneous remission of residual post-therapy plasma Epstein-Barr virus DNA and its prognostic implication in nasopharyngeal carcinoma: a large-scale, big-data intelligence platform-based analysis. Int J Cancer 144:2313\u20132319","journal-title":"Int J Cancer"},{"key":"10678_CR43","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1002\/cam4.3669","volume":"10","author":"W Li","year":"2021","unstructured":"Li W, Chen J, Liang B et al (2021) Long-term monitoring of dynamic changes in plasma EBV DNA for improved prognosis prediction of nasopharyngeal carcinoma. Cancer Med 10:883\u2013894","journal-title":"Cancer Med"}],"container-title":["European Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-024-10678-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00330-024-10678-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-024-10678-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,13]],"date-time":"2024-09-13T13:12:07Z","timestamp":1726233127000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00330-024-10678-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,22]]},"references-count":43,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2024,10]]}},"alternative-id":["10678"],"URL":"https:\/\/doi.org\/10.1007\/s00330-024-10678-8","relation":{},"ISSN":["1432-1084"],"issn-type":[{"value":"1432-1084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,22]]},"assertion":[{"value":"9 November 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 January 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 February 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 March 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The scientific guarantor of this publication is Yan-Ping Mao.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Guarantor"}},{"value":"The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"One of the authors (Shun-Xin Wang, Sun Yat-sen University Cancer Center) who has significant statistical expertise performed all statistical analyses.\u00a0The key raw data underlying this study were uploaded to the Research Data Deposit public platform (RDDA2024775288). Reasonable requests for data sharing should be made to the corresponding author and will be handled in line with the data access and sharing policy of Human Genetic Resource Administration of China and other participating sites outside of China.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statistics and biometry"}},{"value":"Written informed consent was waived by the Institutional Review Board.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"Institutional Review Board approval was obtained. The institutional ethics committee of Sun Yat-sen University Cancer Center approved this study.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The whole study cohort has been reported in our previous study [Luo et al Radiother Oncol 2021], but the difference is that the current study applied radiomics to establish a predictive model and assist clinical decision-making for locoregionally advanced nasopharyngeal carcinoma following induction chemotherapy.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Study subjects or cohorts overlap"}},{"value":"\u2022 retrospective\u2022 observational\u2022 performed at one institution","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Methodology"}}]}}