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Recently, the European Society of Breast Imaging recommended offering MRI screening to women with extremely dense breasts, but the debate on whether to implement it in breast cancer screening programs is ongoing. Insight into the participant experience and willingness to re-attend is important for this discussion.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We calculated the re-attendance rates of the second and third MRI screening rounds of the DENSE trial. Moreover, we calculated age-adjusted odds ratios (ORs) to study the association between characteristics and re-attendance. Women who discontinued MRI screening were asked to provide one or more reasons for this.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The re-attendance rates were 81.3% (3458\/4252) and 85.2% (2693\/3160) in the second and third MRI screening round, respectively. A high age (&gt;\u200965\u00a0years), a very low BMI, lower education, not being employed, smoking, and no alcohol consumption were correlated with lower re-attendance rates. Moderate or high levels of pain, discomfort, or anxiety experienced during the previous MRI screening round were correlated with lower re-attendance rates. Finally, a plurality of women mentioned an examination-related inconvenience as a reason to discontinue screening (39.1% and 34.8% in the second and third screening round, respectively).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>The willingness of women with dense breasts to re-attend an ongoing MRI screening study is high. However, emphasis should be placed on improving the MRI experience to increase the re-attendance rate if widespread supplemental MRI screening is implemented.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Clinical relevance statement<\/jats:title>\n                <jats:p>For many women, MRI is an acceptable screening method, as re-attendance rates were high \u2014 even for screening in a clinical trial setting. To further enhance the (re-)attendance rate, one possible approach could be improving the overall MRI experience.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Key Points<\/jats:title>\n                <jats:p>\u2022 <jats:italic>The willingness to re-attend in an ongoing MRI screening study is high.<\/jats:italic><\/jats:p>\n                <jats:p>\u2022 <jats:italic>Pain, discomfort, and anxiety in the previous MRI screening round were related to lower re-attendance rates.<\/jats:italic><\/jats:p>\n                <jats:p>\u2022 <jats:italic>Emphasis should be placed on improving MRI experience to increase the re-attendance rate in supplemental MRI screening.<\/jats:italic><\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00330-024-10685-9","type":"journal-article","created":{"date-parts":[[2024,4,19]],"date-time":"2024-04-19T09:02:01Z","timestamp":1713517321000},"page":"6334-6347","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Re-attendance in supplemental breast MRI screening rounds of the DENSE trial for women with extremely dense breasts"],"prefix":"10.1007","volume":"34","author":[{"given":"Stefanie G. 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R.M. is a member of the <i>European Radiology<\/i> Advisory Editorial Board (European Society of Breast Imaging), and they have not taken part in the review or selection process of this article. The remaining authors declare no relationships with any companies, whose products or services may be related to the subject matter of the article.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"No complex statistical methods were necessary for this paper.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statistics and biometry"}},{"value":"Written informed consent was obtained from all subjects (patients) in this study.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"Institutional review board approval was obtained.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The trial participants and other trial outcomes have been described earlier:1. Bakker MF, de Lange SV, Pijnappel RM et al (2019) Supplemental MRI screening for women with extremely dense breast tissue.\u00a0<i>New England Journal of Medicine<\/i>\u00a0<i>381<\/i>.22:2091\u201321022. De Lange SV, Bakker MF, Monninkhof EM et al (2018) Reasons for (non) participation in supplemental population-based MRI breast screening for women with extremely dense breasts.\u00a0<i>Clinical Radiology<\/i>\u00a0<i>73<\/i>.8:759-e1.3. Veenhuizen SG, de Lange SV, Bakker MF et al (2021) Supplemental breast MRI for women with extremely dense breasts: results of the second screening round of the DENSE trial.\u00a0<i>Radiology<\/i>\u00a0<i>299<\/i>.2:278\u2013286.The outcomes related to participation in the second and third screening round of DENSE have not been published before.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Study subjects or cohorts overlap"}},{"value":"\u2022 prospective\u2022 randomised controlled trial\u2022 multicentre study","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Methodology"}}]}}