{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T06:46:48Z","timestamp":1782283608186,"version":"3.54.5"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T00:00:00Z","timestamp":1731974400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T00:00:00Z","timestamp":1731974400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Guangzhou Science and Technology Fund","award":["No.202201011053"],"award-info":[{"award-number":["No.202201011053"]}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["No.2021A1515220039"],"award-info":[{"award-number":["No.2021A1515220039"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Radiol"],"DOI":"10.1007\/s00330-024-11205-5","type":"journal-article","created":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T17:41:23Z","timestamp":1732038083000},"page":"2448-2456","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Performance of novel multiparametric second-generation dual-layer spectral detector CT in gouty arthritis"],"prefix":"10.1007","volume":"35","author":[{"given":"Meng","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia-ni","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song-yuan","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi-xian","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui-feng","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kang-yu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-min","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-kai","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2977-2966","authenticated-orcid":false,"given":"Juan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,11,19]]},"reference":[{"key":"11205_CR1","doi-asserted-by":"publisher","first-page":"1843","DOI":"10.1016\/S0140-6736(21)00569-9","volume":"397","author":"N Dalbeth","year":"2021","unstructured":"Dalbeth N, Gosling AL, Gaffo A, Abhishek A (2021) Gout. Lancet 397:1843\u20131855","journal-title":"Lancet"},{"key":"11205_CR2","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1002\/art.40807","volume":"71","author":"M Chen-Xu","year":"2019","unstructured":"Chen-Xu M, Yokose C, Rai SK, Pillinger MH, Choi HK (2019) Contemporary prevalence of gout and hyperuricemia in the United States and decadal trends: the National Health and Nutrition Examination Survey, 2007\u20132016. Arthritis Rheumatol 71:991\u2013999","journal-title":"Arthritis Rheumatol"},{"key":"11205_CR3","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1038\/s41584-020-0441-1","volume":"16","author":"M Dehlin","year":"2020","unstructured":"Dehlin M, Jacobsson L, Roddy E (2020) Global epidemiology of gout: prevalence, incidence, treatment patterns and risk factors. Nat Rev Rheumatol 16:380\u2013390","journal-title":"Nat Rev Rheumatol"},{"key":"11205_CR4","doi-asserted-by":"publisher","first-page":"S11","DOI":"10.1016\/j.semarthrit.2020.04.008","volume":"50","author":"JA Singh","year":"2020","unstructured":"Singh JA, Gaffo A (2020) Gout epidemiology and comorbidities. Semin Arthritis Rheum 50:S11\u2013S16","journal-title":"Semin Arthritis Rheum"},{"key":"11205_CR5","doi-asserted-by":"publisher","first-page":"4174","DOI":"10.1007\/s00330-018-5363-9","volume":"28","author":"AS Klauser","year":"2018","unstructured":"Klauser AS, Halpern EJ, Strobl S et al (2018) Gout of hand and wrist: the value of US as compared with DECT. Eur Radiol 28:4174\u20134181","journal-title":"Eur Radiol"},{"key":"11205_CR6","doi-asserted-by":"crossref","unstructured":"Sapkota SK, Kolade VO, Brit ML (2014) Gouty tophi. J Community Hosp Intern Med Perspect 4:22920","DOI":"10.3402\/jchimp.v4.22920"},{"key":"11205_CR7","doi-asserted-by":"publisher","first-page":"238","DOI":"10.4081\/reumatismo.2011.238","volume":"63","author":"W Grassi","year":"2012","unstructured":"Grassi W, De Angelis R (2012) Clinical features of gout. Reumatismo 63:238\u2013245","journal-title":"Reumatismo"},{"key":"11205_CR8","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1055\/s-2003-43227","volume":"7","author":"A Gentili","year":"2003","unstructured":"Gentili A (2003) Advanced imaging of gout. Semin Musculoskelet Radiol 7:165\u2013174","journal-title":"Semin Musculoskelet Radiol"},{"key":"11205_CR9","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1136\/ard.61.6.493","volume":"61","author":"A Swan","year":"2002","unstructured":"Swan A, Amer H, Dieppe P (2002) The value of synovial fluid assays in the diagnosis of joint disease: a literature survey. Ann Rheum Dis 61:493\u2013498","journal-title":"Ann Rheum Dis"},{"key":"11205_CR10","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1016\/S0140-6736(09)60883-7","volume":"375","author":"P Richette","year":"2010","unstructured":"Richette P, Bardin T (2010) Gout. Lancet 375:318\u2013328","journal-title":"Lancet"},{"key":"11205_CR11","doi-asserted-by":"publisher","first-page":"1533","DOI":"10.1007\/s10067-020-05378-9","volume":"40","author":"Z Zou","year":"2021","unstructured":"Zou Z, Yang M, Wang Y, Zhang B (2021) Gout of ankle and foot: DECT versus US for crystal detection. Clin Rheumatol 40:1533\u20131537","journal-title":"Clin Rheumatol"},{"key":"11205_CR12","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1136\/annrheumdis-2012-202301","volume":"72","author":"PV Chowalloor","year":"2013","unstructured":"Chowalloor PV, Keen HI (2013) A systematic review of ultrasonography in gout and asymptomatic hyperuricaemia. Ann Rheum Dis 72:638\u2013645","journal-title":"Ann Rheum Dis"},{"key":"11205_CR13","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1002\/art.39959","volume":"69","author":"A Ogdie","year":"2017","unstructured":"Ogdie A, Taylor WJ, Neogi T et al (2017) Performance of ultrasound in the diagnosis of gout in a multicenter study: comparison with monosodium urate monohydrate crystal analysis as the gold standard. Arthritis Rheumatol 69:429\u2013438","journal-title":"Arthritis Rheumatol"},{"key":"11205_CR14","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1093\/rheumatology\/kez391","volume":"59","author":"M Gamala","year":"2020","unstructured":"Gamala M, Jacobs JWG, Linn-Rasker SF et al (2020) The performance of dual-energy CT in the classification criteria of gout: a prospective study in subjects with unclassified arthritis. Rheumatology 59:845\u2013851","journal-title":"Rheumatology"},{"key":"11205_CR15","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1148\/radiol.11102485","volume":"261","author":"KN Glazebrook","year":"2011","unstructured":"Glazebrook KN, Guimaraes LS, Murthy NS et al (2011) Identification of intraarticular and periarticular uric acid crystals with dual-energy CT: initial evaluation. Radiology 261:516\u2013524","journal-title":"Radiology"},{"key":"11205_CR16","doi-asserted-by":"publisher","first-page":"1072","DOI":"10.1136\/annrheumdis-2013-205095","volume":"74","author":"T Bongartz","year":"2015","unstructured":"Bongartz T, Glazebrook KN, Kavros SJ et al (2015) Dual-energy CT for the diagnosis of gout: an accuracy and diagnostic yield study. Ann Rheum Dis 74:1072\u20131077","journal-title":"Ann Rheum Dis"},{"key":"11205_CR17","doi-asserted-by":"publisher","first-page":"1549","DOI":"10.1093\/rheumatology\/ket215","volume":"52","author":"N Dalbeth","year":"2013","unstructured":"Dalbeth N (2013) Management of gout in primary care: challenges and potential solutions. Rheumatology 52:1549\u20131550","journal-title":"Rheumatology"},{"key":"11205_CR18","doi-asserted-by":"publisher","first-page":"1365","DOI":"10.1007\/s00296-017-3724-3","volume":"37","author":"Z Zhang","year":"2017","unstructured":"Zhang Z, Zhang X, Sun Y et al (2017) New urate depositions on dual-energy computed tomography in gouty arthritis during urate-lowering therapy. Rheumatol Int 37:1365\u20131372","journal-title":"Rheumatol Int"},{"key":"11205_CR19","doi-asserted-by":"publisher","first-page":"3989","DOI":"10.1007\/s00330-016-4237-2","volume":"26","author":"T Finkenstaedt","year":"2016","unstructured":"Finkenstaedt T, Manoliou A, Toniolo M et al (2016) Gouty arthritis: the diagnostic and therapeutic impact of dual-energy CT. Eur Radiol 26:3989\u20133999","journal-title":"Eur Radiol"},{"key":"11205_CR20","doi-asserted-by":"publisher","first-page":"2101","DOI":"10.1007\/s10067-017-3729-z","volume":"36","author":"DV Modjinou","year":"2017","unstructured":"Modjinou DV, Krasnokutsky S, Gyftopoulos S et al (2017) Comparison of dual-energy CT, ultrasound and surface measurement for assessing tophus dissolution during rapid urate debulking. Clin Rheumatol 36:2101\u20132107","journal-title":"Clin Rheumatol"},{"key":"11205_CR21","first-page":"e75","volume":"1","author":"EG Araujo","year":"2015","unstructured":"Araujo EG, Bayat S, Petsch C et al (2015) Tophus resolution with pegloticase: a prospective dual-energy CT study. Rheum Musculoskelet Dis Open 1:e75","journal-title":"Rheum Musculoskelet Dis Open"},{"key":"11205_CR22","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1007\/s13244-017-0571-4","volume":"8","author":"N Rassouli","year":"2017","unstructured":"Rassouli N, Etesami M, Dhanantwari A, Rajiah P (2017) Detector-based spectral CT with a novel dual-layer technology: principles and applications. Insights Imaging 8:589\u2013598","journal-title":"Insights Imaging"},{"key":"11205_CR23","doi-asserted-by":"publisher","first-page":"3677","DOI":"10.1007\/s00330-017-4737-8","volume":"27","author":"RW van Hamersvelt","year":"2017","unstructured":"van Hamersvelt RW, Willemink MJ, de Jong PA et al (2017) Feasibility and accuracy of dual-layer spectral detector computed tomography for quantification of gadolinium: a phantom study. Eur Radiol 27:3677\u20133686","journal-title":"Eur Radiol"},{"key":"11205_CR24","doi-asserted-by":"publisher","first-page":"1602","DOI":"10.3748\/wjg.v29.i10.1602","volume":"29","author":"LT Mao","year":"2023","unstructured":"Mao LT, Chen WC, Lu JY et al (2023) Quantitative parameters in novel spectral computed tomography: assessment of Ki-67 expression in patients with gastric adenocarcinoma. World J Gastroenterol 29:1602\u20131613","journal-title":"World J Gastroenterol"},{"key":"11205_CR25","doi-asserted-by":"publisher","first-page":"1740","DOI":"10.3390\/diagnostics13101740","volume":"13","author":"PN Franco","year":"2023","unstructured":"Franco PN, Spasiano CM, Maino C et al (2023) Principles and applications of dual-layer spectral CT in gastrointestinal imaging. Diagnostics 13:1740","journal-title":"Diagnostics"},{"key":"11205_CR26","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.ejrad.2017.12.007","volume":"99","author":"T Hickethier","year":"2018","unstructured":"Hickethier T, Byrtus J, Hauger M et al (2018) Utilization of virtual mono-energetic images (MonoE) derived from a dual-layer spectral detector CT (SDCT) for the assessment of abdominal arteries in venous contrast phase scans. Eur J Radiol 99:28\u201333","journal-title":"Eur J Radiol"},{"key":"11205_CR27","doi-asserted-by":"publisher","first-page":"433","DOI":"10.2174\/1573405616666201008150644","volume":"17","author":"Q Meng","year":"2021","unstructured":"Meng Q, Liu M, Deng W et al (2021) Calcium-suppressed technique in dual-layer detector computed tomography to evaluate knee articular cartilage. Curr Med Imaging 17:433\u2013438","journal-title":"Curr Med Imaging"},{"key":"11205_CR28","doi-asserted-by":"publisher","first-page":"2557","DOI":"10.1002\/art.39254","volume":"67","author":"T Neogi","year":"2015","unstructured":"Neogi T, Jansen TL, Dalbeth N et al (2015) 2015 Gout Classification Criteria: an American College of Rheumatology\/European League Against Rheumatism collaborative initiative. Arthritis Rheumatol 67:2557\u20132568","journal-title":"Arthritis Rheumatol"},{"key":"11205_CR29","doi-asserted-by":"publisher","first-page":"S3","DOI":"10.2214\/AJR.12.9116","volume":"199","author":"TR Johnson","year":"2012","unstructured":"Johnson TR (2012) Dual-energy CT: general principles. AJR Am J Roentgenol 199:S3\u2013S8","journal-title":"AJR Am J Roentgenol"},{"key":"11205_CR30","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1148\/radiol.2015142631","volume":"276","author":"CH McCollough","year":"2015","unstructured":"McCollough CH, Leng S, Yu L, Fletcher JG (2015) Dual- and multi-energy CT: principles, technical approaches, and clinical applications. Radiology 276:637\u2013653","journal-title":"Radiology"},{"key":"11205_CR31","doi-asserted-by":"publisher","first-page":"1281","DOI":"10.1007\/s11547-019-01107-8","volume":"124","author":"A Agostini","year":"2019","unstructured":"Agostini A, Borgheresi A, Mari A et al (2019) Dual-energy CT: theoretical principles and clinical applications. Radiol Med 124:1281\u20131295","journal-title":"Radiol Med"},{"key":"11205_CR32","doi-asserted-by":"publisher","first-page":"2486","DOI":"10.1002\/mp.12903","volume":"45","author":"CH Hua","year":"2018","unstructured":"Hua CH, Shapira N, Merchant TE, Klahr P, Yagil Y (2018) Accuracy of electron density, effective atomic number, and iodine concentration determination with a dual-layer dual-energy computed tomography system. Med Phys 45:2486\u20132497","journal-title":"Med Phys"},{"key":"11205_CR33","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/j.diii.2022.11.003","volume":"104","author":"J Greffier","year":"2023","unstructured":"Greffier J, Villani N, Defez D, Dabli D, Si-Mohamed S (2023) Spectral CT imaging: technical principles of dual-energy CT and multi-energy photon-counting CT. Diagn Interv Imaging 104:167\u2013177","journal-title":"Diagn Interv Imaging"},{"key":"11205_CR34","doi-asserted-by":"publisher","first-page":"4601","DOI":"10.21037\/qims-22-2","volume":"12","author":"R Mu","year":"2022","unstructured":"Mu R, Meng Z, Guo Z et al (2022) Dual-layer spectral detector computed tomography parameters can improve diagnostic efficiency of lung adenocarcinoma grading. Quant Imag Med Surg 12:4601\u20134611","journal-title":"Quant Imag Med Surg"},{"key":"11205_CR35","doi-asserted-by":"publisher","first-page":"7323","DOI":"10.1007\/s00330-022-08793-5","volume":"32","author":"A Drljevic-Nielsen","year":"2022","unstructured":"Drljevic-Nielsen A, Mains JR, Thorup K, Andersen MB, Rasmussen F, Donskov F (2022) Early reduction in spectral dual-layer detector CT parameters as favorable imaging biomarkers in patients with metastatic renal cell carcinoma. Eur Radiol 32:7323\u20137334","journal-title":"Eur Radiol"},{"key":"11205_CR36","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.ejrad.2018.06.009","volume":"105","author":"V Neuhaus","year":"2018","unstructured":"Neuhaus V, Lennartz S, Abdullayev N et al (2018) Bone marrow edema in traumatic vertebral compression fractures: diagnostic accuracy of dual-layer detector CT using calcium suppressed images. Eur J Radiol 105:216\u2013220","journal-title":"Eur J Radiol"},{"key":"11205_CR37","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2020.109456","volume":"134","author":"I Simonetti","year":"2021","unstructured":"Simonetti I, Verde F, Palumbo L et al (2021) Dual energy computed tomography evaluation of skeletal traumas. Eur J Radiol 134:109456","journal-title":"Eur J Radiol"},{"key":"11205_CR38","doi-asserted-by":"crossref","unstructured":"Borges AP, Antunes C, Caseiro-Alves F (2023) Spectral CT: current liver applications. Diagnostics 13:1673","DOI":"10.3390\/diagnostics13101673"}],"container-title":["European Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-024-11205-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00330-024-11205-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-024-11205-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T11:06:11Z","timestamp":1745492771000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00330-024-11205-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,19]]},"references-count":38,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2025,5]]}},"alternative-id":["11205"],"URL":"https:\/\/doi.org\/10.1007\/s00330-024-11205-5","relation":{},"ISSN":["1432-1084"],"issn-type":[{"value":"1432-1084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,19]]},"assertion":[{"value":"29 June 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 September 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 October 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 November 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The scientific guarantor of this publication is Juan Li.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Guarantor"}},{"value":"One of the authors of this manuscript (Xiao-min Liu) is an employee of Philips. The remaining authors declare no relationships with any companies whose products or services may be related to the subject matter of the article.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"No complex statistical methods were necessary for this paper.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statistics and biometry"}},{"value":"Written informed consent was waived by the Institutional Review Board.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The study was approved by the Institutional Review Board of the Nanfang Hospital (ethical number NFEC-2023-164).","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"No study subjects or cohorts have been previously reported.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Study subjects or cohorts overlap"}},{"order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Methodology"}}]}}