{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T21:36:16Z","timestamp":1793568976900,"version":"4.5.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100008235","name":"Peking Union Medical College Hospital","doi-asserted-by":"publisher","award":["2025-PUMCH-D-002"],"award-info":[{"award-number":["2025-PUMCH-D-002"]}],"id":[{"id":"10.13039\/501100008235","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Radiol"],"DOI":"10.1007\/s00330-025-12300-x","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T10:26:20Z","timestamp":1769682380000},"page":"4625-4635","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Diagnostic and prognostic performance of MRI-based Node-RADS for regional lymph node assessment in treatment-naive rectal cancer"],"prefix":"10.1007","volume":"36","author":[{"given":"Runzhe","family":"Xue","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingjuan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongbo","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shitian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weidong","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4278-2165","authenticated-orcid":false,"given":"Huadan","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,1,29]]},"reference":[{"key":"12300_CR1","first-page":"229","volume":"74","author":"F Bray","year":"2024","unstructured":"Bray F, Laversanne M, Sung H et al (2024) Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 74:229\u2013263","journal-title":"CA Cancer J Clin"},{"key":"12300_CR2","first-page":"233","volume":"73","author":"RL Siegel","year":"2023","unstructured":"Siegel RL, Wagle NS, Cercek A, Smith RA, Jemal A (2023) Colorectal cancer statistics, 2023. CA Cancer J Clin 73:233\u2013254","journal-title":"CA Cancer J Clin"},{"key":"12300_CR3","doi-asserted-by":"publisher","first-page":"2570","DOI":"10.3390\/diagnostics14222570","volume":"14","author":"H Akkaya","year":"2024","unstructured":"Akkaya H, Dilek O, \u00d6zdemir S et al (2024) Rectal cancer and lateral lymph node staging: interobserver agreement and success in predicting locoregional recurrence. Diagnostics (Basel) 14:2570","journal-title":"Diagnostics (Basel)"},{"key":"12300_CR4","doi-asserted-by":"publisher","first-page":"e221529","DOI":"10.1148\/radiol.221529","volume":"307","author":"VS Jayaprakasam","year":"2023","unstructured":"Jayaprakasam VS, Alvarez J, Omer DM, Gollub MJ, Smith JJ, Petkovska I (2023) Watch-and-wait approach to rectal cancer: the role of imaging. Radiology 307:e221529","journal-title":"Radiology"},{"key":"12300_CR5","first-page":"10","volume":"21","author":"DDB Bates","year":"2022","unstructured":"Bates DDB, Homsi ME, Chang KJ, Lalwani N, Horvat N, Sheedy SP (2022) MRI for rectal cancer: staging, mrCRM, EMVI, lymph node staging and post-treatment response. Clin Colorectal Cancer 21:10\u201318","journal-title":"Clin Colorectal Cancer"},{"key":"12300_CR6","doi-asserted-by":"publisher","first-page":"83","DOI":"10.3857\/roj.2021.00108","volume":"39","author":"P Haddad","year":"2021","unstructured":"Haddad P, Ghalehtaki R, Saeedian A, Farhan F, Babaei M, Aghili M (2021) Current approaches in intensification of long-course chemoradiotherapy in locally advanced rectal cancer: a review. Radiat Oncol J 39:83\u201390","journal-title":"Radiat Oncol J"},{"key":"12300_CR7","doi-asserted-by":"publisher","first-page":"1467","DOI":"10.1016\/S0140-6736(19)32319-0","volume":"394","author":"E Dekker","year":"2019","unstructured":"Dekker E, Tanis PJ, Vleugels JLA, Kasi PM, Wallace MB (2019) Colorectal cancer. Lancet 394:1467\u20131480","journal-title":"Lancet"},{"key":"12300_CR8","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1007\/s11605-017-3568-x","volume":"22","author":"J Gr\u00f6ne","year":"2018","unstructured":"Gr\u00f6ne J, Loch FN, Taupitz M, Schmidt C, Kreis ME (2018) Accuracy of various lymph node staging criteria in rectal cancer with magnetic resonance imaging. J Gastrointest Surg 22:146\u2013153","journal-title":"J Gastrointest Surg"},{"key":"12300_CR9","doi-asserted-by":"publisher","first-page":"2212","DOI":"10.1245\/s10434-011-2210-5","volume":"19","author":"E Al-Sukhni","year":"2012","unstructured":"Al-Sukhni E, Milot L, Fruitman M et al (2012) Diagnostic accuracy of MRI for assessment of T category, lymph node metastases, and circumferential resection margin involvement in patients with rectal cancer: a systematic review and meta-analysis. Ann Surg Oncol 19:2212\u20132223","journal-title":"Ann Surg Oncol"},{"key":"12300_CR10","doi-asserted-by":"publisher","first-page":"6116","DOI":"10.1007\/s00330-020-07572-4","volume":"31","author":"FHJ Elsholtz","year":"2021","unstructured":"Elsholtz FHJ, Asbach P, Haas M et al (2021) Introducing the node reporting and data system 1.0 (Node-RADS): a concept for standardized assessment of lymph nodes in cancer. Eur Radiol 31:6116\u20136124","journal-title":"Eur Radiol"},{"key":"12300_CR11","doi-asserted-by":"publisher","first-page":"3183","DOI":"10.1007\/s00330-023-10352-5","volume":"34","author":"FN Loch","year":"2024","unstructured":"Loch FN, Beyer K, Kreis ME et al (2024) Diagnostic performance of node reporting and data system (Node-RADS) for regional lymph node staging of gastric cancer by CT. Eur Radiol 34:3183\u20133193","journal-title":"Eur Radiol"},{"key":"12300_CR12","doi-asserted-by":"publisher","first-page":"7734","DOI":"10.1007\/s00330-024-10828-y","volume":"34","author":"F Pediconi","year":"2024","unstructured":"Pediconi F, Maroncelli R, Pasculli M et al (2024) Performance of MRI for standardized lymph nodes assessment in breast cancer: Are we ready for Node-RADS? Eur Radiol 34:7734\u20137745","journal-title":"Eur Radiol"},{"key":"12300_CR13","doi-asserted-by":"publisher","DOI":"10.1186\/s40644-022-00506-x","volume":"22","author":"H-J Meyer","year":"2022","unstructured":"Meyer H-J, Schnarkowski B, Pappisch J et al (2022) CT texture analysis and node-RADS CT score of mediastinal lymph nodes\u2014diagnostic performance in lung cancer patients. Cancer Imaging 22:75","journal-title":"Cancer Imaging"},{"key":"12300_CR14","doi-asserted-by":"publisher","unstructured":"Fang Y, Chen M, Zheng X et al (2024) Validation of the node reporting and data system (Node-RADS) for standardized CT evaluation of regional lymph nodes in esophageal squamous cell carcinoma patients. Eur Radiol. https:\/\/doi.org\/10.1007\/s00330-024-11234-0","DOI":"10.1007\/s00330-024-11234-0"},{"key":"12300_CR15","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.diii.2024.10.005","volume":"106","author":"X Bai","year":"2025","unstructured":"Bai X, Peng C, Liu B et al (2025) Diagnostic and prognostic value of MRI-based Node-RADS for the assessm ent of regional lymph node metastasis in renal cell carcinoma. Diagn Interv Imaging 106:117\u2013125","journal-title":"Diagn Interv Imaging"},{"key":"12300_CR16","doi-asserted-by":"publisher","unstructured":"Sun Y, Xiao H, Wen L et al (2025) Value of post-NAC CT-based node-RADS score for predicting residual lymph node metastasis and survival outcome of locally advanced gastric cancer. Abdom Radiol. https:\/\/doi.org\/10.1007\/s00261-025-04843-w","DOI":"10.1007\/s00261-025-04843-w"},{"key":"12300_CR17","doi-asserted-by":"crossref","unstructured":"Niu Y, Wen L, Yang Y et al (2024) Diagnostic performance of node reporting and data system (Node-RADS) for assessing mesorectal lymph node in rectal cancer by CT. BMC cancer 24:716","DOI":"10.1186\/s12885-024-12487-0"},{"key":"12300_CR18","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1007\/s00261-024-04497-0","volume":"50","author":"Y Niu","year":"2025","unstructured":"Niu Y, Yu S, Chen P et al (2025) Diagnostic performance of Node-RADS score for mesorectal lymph node metastasis in rectal cancer. Abdom Radiol 50:38\u201348","journal-title":"Abdom Radiol"},{"key":"12300_CR19","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1007\/s00432-025-06196-9","volume":"151","author":"L Jiang","year":"2025","unstructured":"Jiang L, Zhuang Z, Tang X et al (2025) Diagnostic performance of node-RADS classification for primary lymph n ode assessment in rectal cancer: a modality benchmarking study. J Cancer Res Clin Oncol 151:145","journal-title":"J Cancer Res Clin Oncol"},{"key":"12300_CR20","doi-asserted-by":"publisher","first-page":"2792","DOI":"10.1007\/s00261-023-03893-2","volume":"48","author":"S Lee","year":"2023","unstructured":"Lee S, Kassam Z, Baheti AD et al (2023) Rectal cancer lexicon 2023 revised and updated consensus statement from the Society of Abdominal Radiology Colorectal and Anal Cancer Diseas e-Focused Panel. Abdom Radiol (NY) 48:2792\u20132806","journal-title":"Abdom Radiol (NY)"},{"key":"12300_CR21","doi-asserted-by":"publisher","first-page":"1454","DOI":"10.1245\/s10434-018-6462-1","volume":"25","author":"MR Weiser","year":"2018","unstructured":"Weiser MR (2018) AJCC 8th edition: colorectal cancer. Annals of surgical oncology 25:1454\u20131455","journal-title":"Annals of surgical oncology"},{"key":"12300_CR22","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1148\/rg.2019180114","volume":"39","author":"N Horvat","year":"2019","unstructured":"Horvat N, Carlos Tavares Rocha C, Clemente Oliveira B, Petkovska I, Gollub MJ (2019) MRI of rectal cancer: tumor staging, imaging techniques, and management. Radiographics 39:367\u2013387","journal-title":"Radiographics"},{"key":"12300_CR23","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1016\/j.clinimag.2021.08.010","volume":"80","author":"JS Golia Pernicka","year":"2021","unstructured":"Golia Pernicka JS, Bates DDB, Fuqua JL 3rd et al (2021) Meaningful words in rectal MRI synoptic reports: How \u201cpolypoid\u201d may be prognostic. Clin Imaging 80:371\u2013376","journal-title":"Clin Imaging"},{"key":"12300_CR24","doi-asserted-by":"publisher","first-page":"3508","DOI":"10.1007\/s00261-019-02170-5","volume":"44","author":"TA Hope","year":"2019","unstructured":"Hope TA, Gollub MJ, Arya S et al (2019) Rectal cancer lexicon: consensus statement from the society of abdomin al radiology rectal & anal cancer disease-focused panel. Abdom Radiol (NY) 44:3508\u20133517","journal-title":"Abdom Radiol (NY)"},{"key":"12300_CR25","doi-asserted-by":"publisher","first-page":"3364","DOI":"10.1007\/s00261-022-03612-3","volume":"47","author":"Z Kassam","year":"2022","unstructured":"Kassam Z, Lang R, Arya S et al (2022) Update to the structured MRI report for primary staging of rectal canc er : perspective from the SAR disease focused panel on rectal and anal cancer. Abdom Radiol 47:3364\u20133374","journal-title":"Abdom Radiol"},{"key":"12300_CR26","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1007\/s13244-016-0534-1","volume":"8","author":"AP Brady","year":"2017","unstructured":"Brady AP (2017) Error and discrepancy in radiology: Inevitable or avoidable? Insights Imaging 8:171\u2013182","journal-title":"Insights Imaging"},{"key":"12300_CR27","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1186\/s13244-023-01521-7","volume":"14","author":"L Zhang","year":"2023","unstructured":"Zhang L, Wen X, Li JW, Jiang X, Yang XF, Li M (2023) Diagnostic error and bias in the department of radiology: a pictorial essay. Insights Imaging 14:163","journal-title":"Insights Imaging"},{"key":"12300_CR28","doi-asserted-by":"publisher","first-page":"611","DOI":"10.2214\/AJR.12.10375","volume":"201","author":"CS Lee","year":"2013","unstructured":"Lee CS, Nagy PG, Weaver SJ, Newman-Toker DE (2013) Cognitive and system factors contributing to diagnostic errors in radiology. AJR Am J Roentgenol 201:611\u2013617","journal-title":"AJR Am J Roentgenol"},{"key":"12300_CR29","doi-asserted-by":"publisher","first-page":"1139","DOI":"10.6004\/jnccn.2022.0051","volume":"20","author":"AB Benson","year":"2022","unstructured":"Benson AB, Venook AP, Al-Hawary MM et al (2022) Rectal cancer, version 2.2022, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw 20:1139\u20131167","journal-title":"J Natl Compr Canc Netw"},{"key":"12300_CR30","doi-asserted-by":"publisher","first-page":"e243627","DOI":"10.1148\/radiol.243627","volume":"317","author":"Y Feng","year":"2025","unstructured":"Feng Y, Hu T, Gu W et al (2025) Mesorectal fascia involvement by tumor deposits or extramural vascular invasion at MRI predicts prognosis in rectal cancer. Radiology 317:e243627","journal-title":"Radiology"},{"key":"12300_CR31","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1200\/JCO.2003.10.016","volume":"21","author":"EP Mitchell","year":"2003","unstructured":"Mitchell EP (2003) Prognosis after rectal cancer treatment in blacks and whites: Advanced stage at diagnosis or other factors? J Clin Oncol 21:397\u2013398","journal-title":"J Clin Oncol"}],"container-title":["European Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-025-12300-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00330-025-12300-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-025-12300-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T12:26:17Z","timestamp":1779798377000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00330-025-12300-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,29]]},"references-count":31,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2026,6]]}},"alternative-id":["12300"],"URL":"https:\/\/doi.org\/10.1007\/s00330-025-12300-x","relation":{},"ISSN":["1432-1084"],"issn-type":[{"value":"1432-1084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,29]]},"assertion":[{"value":"8 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 December 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 December 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 January 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The scientific guarantor of this publication is Huadan Xue.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Guarantor"}},{"value":"The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Runzhe Xue and Jingjuan Liu have significant statistical expertise.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statistics and biometry"}},{"value":"Written informed consent was waived by the Institutional Review Board.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"Institutional Review Board of Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (Project No. K25C2412) approval was obtained.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"None.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Study subjects or cohorts overlap"}},{"order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Methodology"}}]}}