{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T16:08:44Z","timestamp":1774886924226,"version":"3.50.1"},"reference-count":7,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:00:00Z","timestamp":1770681600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:00:00Z","timestamp":1770681600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Radiol"],"DOI":"10.1007\/s00330-026-12342-9","type":"journal-article","created":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T15:51:45Z","timestamp":1770738705000},"page":"3052-3053","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Reply to the Letter to the Editor: Evaluation of an artificial intelligence model based on multiparametric transrectal ultrasound for localizing clinically significant prostate cancer by simulation of targeted biopsies"],"prefix":"10.1007","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8448-4193","authenticated-orcid":false,"given":"D. L.","family":"van den Kroonenberg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. W.","family":"Postema","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. P.","family":"Beerlage","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. R.","family":"Oddens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,2,10]]},"reference":[{"key":"12342_CR1","doi-asserted-by":"publisher","unstructured":"van den Kroonenberg DL, Delberghe F, Jager A et al (2025) Evaluation of an artificial intelligence model based on multiparametric transrectal ultrasound for localizing clinically significant prostate cancer by simulation of targeted biopsies. Eur Radiol. https:\/\/doi.org\/10.1007\/s00330-025-12114-x","DOI":"10.1007\/s00330-025-12114-x"},{"key":"12342_CR2","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.euros.2024.06.012","volume":"66","author":"DL van den Kroonenberg","year":"2024","unstructured":"van den Kroonenberg DL, Jager A, Garrido-Utrilla A et al (2024) Clinical validation of multiparametric ultrasound for detecting clinically significant prostate cancer using computer-aided diagnosis: a direct comparison with the magnetic resonance imaging pathway. Eur Urol Open Sci 66:60\u201366","journal-title":"Eur Urol Open Sci"},{"key":"12342_CR3","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1080\/17434440.2025.2473632","volume":"22","author":"DL van den Kroonenberg","year":"2025","unstructured":"van den Kroonenberg DL, Went J, Jager A et al (2025) Developing a training for 3D transrectal multiparametric ultrasound of the prostate: a human factors engineering approach. Expert Rev Med Devices 22:361\u2013367","journal-title":"Expert Rev Med Devices"},{"key":"12342_CR4","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.euros.2025.03.005","volume":"75","author":"DL van den Kroonenberg","year":"2025","unstructured":"van den Kroonenberg DL, Delberghe FT, Jager A et al (2025) Development and validation of an algorithm for segmentation of the prostate and its zones from three-dimensional transrectal multiparametric ultrasound images. Eur Urol Open Sci 75:48\u201354","journal-title":"Eur Urol Open Sci"},{"key":"12342_CR5","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.euros.2022.12.018","volume":"49","author":"A Jager","year":"2023","unstructured":"Jager A, Postema AW, Mischi M, Wijkstra H, Beerlage HP, Oddens JR (2023) Clinical trial protocol: developing an image classification algorithm for prostate cancer diagnosis on three-dimensional multiparametric transrectal ultrasound. Eur Urol Open Sci 49:32\u201343","journal-title":"Eur Urol Open Sci"},{"key":"12342_CR6","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1007\/s00428-023-03589-4","volume":"483","author":"A Jager","year":"2023","unstructured":"Jager A, Postema AW, van der Linden H et al (2023) Reliability of whole mount radical prostatectomy histopathology as the ground truth for artificial intelligence assisted prostate imaging. Virchows Arch 483:197\u2013206","journal-title":"Virchows Arch"},{"key":"12342_CR7","doi-asserted-by":"publisher","DOI":"10.1186\/s12894-025-01736-4","volume":"25","author":"A Jager","year":"2025","unstructured":"Jager A, Zwart MJ, Postema AW et al (2025) Development and validation of a framework for registration of whole-mount radical prostatectomy histopathology with three-dimensional transrectal ultrasound. BMC Urol 25:73","journal-title":"BMC Urol"}],"container-title":["European Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-026-12342-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00330-026-12342-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-026-12342-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T15:19:19Z","timestamp":1774883959000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00330-026-12342-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,10]]},"references-count":7,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2026,4]]}},"alternative-id":["12342"],"URL":"https:\/\/doi.org\/10.1007\/s00330-026-12342-9","relation":{},"ISSN":["1432-1084"],"issn-type":[{"value":"1432-1084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,10]]},"assertion":[{"value":"22 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 December 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 January 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 February 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The scientific guarantor of this publication is Jorg Oddens.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Guarantor"}},{"value":"The authors of this manuscript declare relationships with the following companies: Arnoud W. Postema is a scientific advisor for Angiogenesis Analytics, for which he receives compensation. Harrie P. Beerlage is chief of the clinical board for Angiogenesis Analytics.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statistics and biometry"}},{"value":"Only if the study is on human subjects: written informed consent was obtained from all subjects (patients) in the original study.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"Institutional Review Board approval was obtained for the original study.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"This is not applicable to this study.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Study subjects or cohorts overlap"}},{"order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Methodology"}}]}}