{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:20:08Z","timestamp":1760782808399},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mamm Genome"],"published-print":{"date-parts":[[2006,1]]},"DOI":"10.1007\/s00335-005-0102-3","type":"journal-article","created":{"date-parts":[[2006,1,13]],"date-time":"2006-01-13T13:51:49Z","timestamp":1137160309000},"page":"67-76","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Fine-mapping and candidate gene analysis of bovine spinal muscular atrophy"],"prefix":"10.1007","volume":"17","author":[{"given":"Stefan","family":"Krebs","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivica","family":"Medugorac","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingolf","family":"Russ","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pete","family":"Ossent","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich","family":"Bleul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Schmahl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"F\u00f6rster","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2006,1,13]]},"reference":[{"key":"102_CR1","first-page":"252","volume":"53","author":"RW Cottingham Jr","year":"1993","unstructured":"Cottingham RW Jr, Idury RM, Schaffer AA (1993) Faster sequential genetic linkage computations.Am J Hum Genet 53: 252\u2013263","journal-title":"Am J Hum Genet"},{"key":"102_CR2","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.molcel.2005.03.008","volume":"18","author":"T Gao","year":"2005","unstructured":"Gao T, Furnari F, Newton AC (2005) PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis,and suppresses tumor growth. Mol Cell 18: 13\u201324","journal-title":"Mol Cell"},{"key":"102_CR3","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1038\/ng1001-166","volume":"29","author":"S Hadano","year":"2001","unstructured":"Hadano S, Hand CK, Osuga H, Yanagisawa Y, Otomo A, et al. (2001) A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2. Nat Genet 29: 166\u2013173","journal-title":"Nat Genet"},{"key":"102_CR4","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/0022-510X(93)90244-S","volume":"118","author":"T Hiraga","year":"1992","unstructured":"Hiraga T, Leipold HW, Cash WC, Troyer DL (1992) Reduced numbers and intense anti-ubiquitin immunostaining of bovine motor neurons affected with spinal muscular atrophy. J Neurol Sci 118: 43\u201347","journal-title":"J Neurol Sci"},{"key":"102_CR5","doi-asserted-by":"publisher","first-page":"1987","DOI":"10.1101\/gr.2741704","volume":"14","author":"N Ihara","year":"2004","unstructured":"Ihara N, Takasuga A, Mizoshita K, Takeda H, Sugimoto M, et al. (2004) A comprehensive genetic map of the cattle genome based on 3802 microsatellites. Genome Res 14: 1987\u20131998","journal-title":"Genome Res"},{"key":"102_CR6","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1016\/j.ygeno.2004.12.007","volume":"85","author":"T Itoh","year":"2005","unstructured":"Itoh T, Watanabe T, Ihara N, Mariani P, Beattie CW, et al. (2005) A comprehensive radiation hybrid map of the bovine genome comprising 5593 loci. Genomics 85: 413\u2013424","journal-title":"Genomics"},{"key":"102_CR7","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1038\/37144","volume":"390","author":"H Iwahashi","year":"1997","unstructured":"Iwahashi H, Eguchi Y, Yasuhara N, Hanafusa T, Matsuzawa Y, et al. (1997) Synergistic anti-apoptotic activity between Bcl-2 and SMN implicated in spinal muscular atrophy. Nature 390: 413\u2013417","journal-title":"Nature"},{"key":"102_CR8","doi-asserted-by":"publisher","first-page":"13312","DOI":"10.1073\/pnas.230364197","volume":"97","author":"DA Kerr","year":"2000","unstructured":"Kerr DA, Nery JP, Traystman RJ, Chau BN, Hardwick JM (2000) Survival motor neuron protein modulates neuron-specific apoptosis. Proc Natl Acad Sci U S A 97: 13312\u201313317","journal-title":"Proc Natl Acad Sci USA"},{"key":"102_CR9","doi-asserted-by":"publisher","first-page":"e37","DOI":"10.1093\/nar\/gng037","volume":"31","author":"S Krebs","year":"2003","unstructured":"Krebs S, Medugorac I, Seichter D, Forster M (2003) RNaseCut: a MALDI mass spectrometry-based method for SNP discovery. Nucleic Acids Res 31: e37","journal-title":"Nucleic Acids Res"},{"key":"102_CR10","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1002\/1097-4547(20001101)62:3<346::AID-JNR4>3.0.CO;2-D","volume":"62","author":"V La Bella","year":"2000","unstructured":"La Bella V, Kallenbach S, Pettmann B (2000) Expression and subcellular localization of two isoforms of the survival motor neuron protein in different cell types. J Neurosci Res 62: 346\u2013356","journal-title":"J Neurosci Res"},{"key":"102_CR11","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.1073\/pnas.84.8.2363","volume":"84","author":"ES Lander","year":"1987","unstructured":"Lander ES, Green P (1987) Construction of multilocus genetic linkage maps in humans. Proc Natl Acad Sci U S A 84: 2363\u20132367","journal-title":"Proc Natl Acad Sci USA"},{"key":"102_CR12","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.1101\/gr.1560203","volume":"13","author":"DM Larkin","year":"2003","unstructured":"Larkin DM, Everts-van der Wind A, Rebeiz M, Schweitzer PA, Bachman S, et al. (2003) A cattle-human comparative map built with cattle BAC-ends and human genome sequence. Genome Res 13: 1966\u20131972","journal-title":"Genome Res"},{"key":"102_CR13","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1007\/s003359901027","volume":"10","author":"NJ Larsen","year":"1999","unstructured":"Larsen NJ, Hayes H, Bishop M, Davis SK, Taylor JF, et al. (1999) A comparative linkage and physical map of bovine chromosome 24 with human chromosome 18. Mamm Genome10: 482\u2013487","journal-title":"Mamm Genome"},{"key":"102_CR14","first-page":"460","volume":"36","author":"GM Lathrop","year":"1984","unstructured":"Lathrop GM, Lalouel JM (1984) Easy calculations of LOD scores and genetic risks on small computers. Am J Hum Genet 36: 460\u2013465","journal-title":"Am J Hum Genet"},{"key":"102_CR15","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.1016\/S0092-8674(00)80367-0","volume":"90","author":"Q Liu","year":"1997","unstructured":"Liu Q, Fischer U, Wang F, Dreyfuss G (1997) The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. Cell 90: 1013\u20131021","journal-title":"Cell"},{"key":"102_CR16","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1007\/s00335-002-3024-3","volume":"14","author":"I Medugorac","year":"2003","unstructured":"Medugorac I, Kemter J, Russ I, Pietrowski D, N\u00fcske S, et al. (2003) Mapping of the bovine spinal muscular atrophy locus to Chromosome 24. Mamm Genome 14: 383\u2013391","journal-title":"Mamm Genome"},{"key":"102_CR17","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/S0896-6273(00)80282-2","volume":"17","author":"TM Michaelidis","year":"1996","unstructured":"Michaelidis TM, Sendtner M, Cooper JD, Airaksinen MS, Holtmann B, et al. (1996) Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development. Neuron 17: 75\u201389","journal-title":"Neuron"},{"key":"102_CR18","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.neuron.2004.06.021","volume":"43","author":"P Pasinelli","year":"2004","unstructured":"Pasinelli P, Belford ME, Lennon N, Bacskai BJ, Hyman BT, et al. (2004) Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria. Neuron 43: 19\u201330","journal-title":"Neuron"},{"key":"102_CR19","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1046\/j.1365-2052.1999.00382-10.x","volume":"30","author":"D Pietrowski","year":"1999","unstructured":"Pietrowski D, Kemter J, Medugorac I, Goldammer T, Foerster M (1999) An AluI PCR-RFLP in the bovine survival motor neuron gene (SMN). Anim Genet 30: 168","journal-title":"Anim Genet"},{"key":"102_CR20","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1093\/hmg\/ddi003","volume":"14","author":"E Reid","year":"2005","unstructured":"Reid E, Connell J, Edwards TL, Duley S, Brown SE, et al. (2005) The hereditary spastic paraplegia protein spastin interacts with the ESCRT-III complex-associated endosomal protein CHMP1B. Hum Mol Genet 14: 19\u201338","journal-title":"Hum Mol Genet"},{"key":"102_CR21","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1038\/nrg705","volume":"3","author":"RV Samonte","year":"2002","unstructured":"Samonte RV, Eichler EE (2002) Segmental duplications and the evolution of the primate genome.Nat Rev Genet 3: 65\u201372","journal-title":"Nat Rev Genet"},{"key":"102_CR22","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1038\/sj.cdd.4400660","volume":"7","author":"K Sato","year":"2000","unstructured":"Sato K, Eguchi Y, Kodama TS, Tsujimoto Y (2000) Regions essential for the interaction between Bcl-2 and SMN, the spinal muscular atrophy disease gene product. Cell Death Differ 7: 374\u2013383","journal-title":"Cell Death Differ"},{"key":"102_CR23","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1002\/neu.10108","volume":"53","author":"N Sato","year":"2002","unstructured":"Sato N, Sakuma C, Kato H, Milligan CE, Oppenheim RW, et al. (2002) Bcl-2 rescues motoneurons from early cell death in the cervical spinal cord of the chicken embryo. J Neurobiol 53: 381\u2013390","journal-title":"J Neurobiol"},{"key":"102_CR24","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1186\/1297-9686-36-1-105","volume":"36","author":"L Schibler","year":"2004","unstructured":"Schibler L, Roig A, Mahe MF, Save JC, Gautier M, et al. (2004) A first generation bovine BAC-based physical map.Genet Sel Evol 36: 105\u2013122","journal-title":"Genet Sel Evol"},{"key":"102_CR25","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1002\/j.1460-2075.1988.tb02791.x","volume":"7","author":"M Seto","year":"1988","unstructured":"Seto M, Jaeger U, Hockett RD, Graninger W, Bennett S, et al. (1988) Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2-Ig fusion gene in lymphoma. EMBO J. 7: 123\u2013131","journal-title":"EMBO J"},{"key":"102_CR26","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1053\/jcpa.2002.0616","volume":"128","author":"S Siso","year":"2003","unstructured":"Siso S, Piumarola M, Ferrer I (2003) Cell death and decreased synaptic protein expression in the ventral horn of Holstein-Friesian calves with spinal muscular atrophy. J Comp Pathol 128: 132\u2013139","journal-title":"J Comp Pathol"},{"key":"102_CR27","doi-asserted-by":"publisher","first-page":"806","DOI":"10.1038\/ng1609","volume":"37","author":"G Skibinski","year":"2005","unstructured":"Skibinski G, Parkinson NJ, Brown JM, Chakrabarti L, Lloyd SL, et al. (2005) Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia. Nat Genet 37: 806\u2013808","journal-title":"Nat Genet"},{"key":"102_CR28","first-page":"1323","volume":"58","author":"E Sobel","year":"1996","unstructured":"Sobel E, Lange K (1996) Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics. Am J Hum Genet 58: 1323\u20131337","journal-title":"Am J Hum Genet"},{"key":"102_CR29","doi-asserted-by":"publisher","first-page":"1624","DOI":"10.1093\/brain\/awf155","volume":"125","author":"C Soler-Botija","year":"2002","unstructured":"Soler-Botija C, Ferrer I, Gich I, Baiget M, Tizzano EF (2002) Neuronal death is enhanced and begins during foetal development in type I spinal muscular atrophy spinal cord. Brain 125: 1624\u20131634","journal-title":"Brain"},{"key":"102_CR30","unstructured":"Terwilliger JD, Ott J (1994) Handbook of human genetic linkage (Baltimore, MD: The Johns Hopkins University Press)"},{"key":"102_CR31","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1177\/104063879300500233","volume":"5","author":"D Troyer","year":"1992","unstructured":"Troyer D, Cash WC, Vestweber J, Hiraga T, Leipold HW (1992) Review of spinal muscular atrophy (SMA) in brown Swiss cattle. J Vet Diagn Invest 5: 303\u2013306","journal-title":"J Vet Diagn Invest"},{"key":"102_CR32","doi-asserted-by":"crossref","first-page":"9119","DOI":"10.1523\/JNEUROSCI.20-24-09119.2000","volume":"20","author":"S Vukosavic","year":"2000","unstructured":"Vukosavic S, Stefanis L, Jackson-Lewis V, Guegan C, Romero N, et al. (2000) Delaying caspase activation by Bcl-2: A clue to disease retardation in a transgenic mouse model of amyotrophic lateral sclerosis. J Neurosci 20: 9119\u20139125","journal-title":"J Neurosci"},{"key":"102_CR33","doi-asserted-by":"publisher","first-page":"2751","DOI":"10.1093\/hmg\/11.22.2751","volume":"11","author":"S Vyas","year":"2002","unstructured":"Vyas S, Bechade C, Riveau B, Downward J, Triller A (2002) Involvement of survival motor neuron (SMN) protein in cell death. Hum Mol Genet 11: 2751\u20132764","journal-title":"Hum Mol Genet"}],"container-title":["Mammalian Genome"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00335-005-0102-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00335-005-0102-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00335-005-0102-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00335-005-0102-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,14]],"date-time":"2022-05-14T02:13:26Z","timestamp":1652494406000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00335-005-0102-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["102"],"URL":"https:\/\/doi.org\/10.1007\/s00335-005-0102-3","relation":{},"ISSN":["0938-8990","1432-1777"],"issn-type":[{"value":"0938-8990","type":"print"},{"value":"1432-1777","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,1]]},"assertion":[{"value":"28 July 2005","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 September 2005","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 January 2006","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}