{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T01:01:59Z","timestamp":1778893319000,"version":"3.51.4"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mamm Genome"],"published-print":{"date-parts":[[2007,1]]},"DOI":"10.1007\/s00335-006-0016-8","type":"journal-article","created":{"date-parts":[[2007,1,22]],"date-time":"2007-01-22T08:34:50Z","timestamp":1169454890000},"page":"43-52","source":"Crossref","is-referenced-by-count":10,"title":["Linkage mapping of the locus for inherited ovine arthrogryposis (IOA) to sheep Chromosome 5"],"prefix":"10.1007","volume":"18","author":[{"given":"Angela M.","family":"Murphy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David E.","family":"MacHugh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen D.E.","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik","family":"Scraggs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris S.","family":"Haley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David J.","family":"Lynn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurice P.","family":"Boland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael L.","family":"Doherty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2007,1,22]]},"reference":[{"key":"16_CR1","first-page":"1153","volume":"55","author":"M Bamshad","year":"1994","unstructured":"Bamshad M, Watkins WS, Zenger RK, Bohnsack JF, Carey JC, et al. (1994) A gene for distal arthrogryposis type I maps to the pericentromeric region of chromosome 9. Am J Hum Genet 55, 1153\u20131158","journal-title":"Am J Hum Genet"},{"key":"16_CR2","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1093\/genetics\/138.3.963","volume":"138","author":"GA Churchill","year":"1994","unstructured":"Churchill GA, Doerge RW (1994) Empirical threshold values for quantitative trait mapping. Genetics 138, 963\u2013971","journal-title":"Genetics"},{"key":"16_CR3","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1093\/genetics\/140.2.703","volume":"140","author":"AM Crawford","year":"1995","unstructured":"Crawford AM, Dodds KG, Ede AJ, Pierson CA, Montgomery GW, et al. (1995) An autosomal genetic linkage map of the sheep genome. Genetics 140, 703\u2013724","journal-title":"Genetics"},{"key":"16_CR4","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1007\/s003359900726","volume":"9","author":"MJ Gortari de","year":"1998","unstructured":"de Gortari MJ, Freking BA, Cuthbertson RP, Kappes SM, Keele JW, et al. (1998) A second-generation linkage map of the sheep genome. Mamm Genome 9, 204\u2013209","journal-title":"Mamm Genome"},{"key":"16_CR5","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1136\/vr.146.26.748","volume":"146","author":"ML Doherty","year":"2000","unstructured":"Doherty ML, Kelly EP, Healy AM, Callanan JJ, Crosby TF, et al. (2000) Congenital arthrogryposis: an inherited limb deformity in pedigree Suffolk lambs. Vet Rec 146, 748\u2013753","journal-title":"Vet Rec"},{"key":"16_CR6","volume-title":"Salamon\u2019s artificial insemination of sheep and goats","author":"G Evans","year":"1987","unstructured":"Evans G, Maxwell WMC, Salamon S (1987) Salamon\u2019s artificial insemination of sheep and goats. (Sydney: Butterworths)"},{"key":"16_CR7","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1007\/s00335-004-2403-3","volume":"15","author":"S Genini","year":"2004","unstructured":"Genini S, Malek M, Spilar S, Nguyen TT, Menetrey F, et al. (2004) Arthrogryposis multiplex congenita (AMC), a hereditary disease in swine, maps to chromosome 5 by linkage analysis. Mamm Genome 15, 935\u2013941","journal-title":"Mamm Genome"},{"key":"16_CR8","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S0387-7604(98)00037-0","volume":"20","author":"N Gordon","year":"1998","unstructured":"Gordon N (1998) Arthrogryposis multiplex congenita. Brain Dev 20, 507\u2013511","journal-title":"Brain Dev"},{"key":"16_CR9","volume-title":"Documentation for CRI-MAP, version 2.4","author":"P Green","year":"1990","unstructured":"Green P, Falls KA, Crooks S (1990) Documentation for CRI-MAP, version 2.4. (St Louis, MO: Washington University School of Medicine)"},{"key":"16_CR10","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1038\/hdy.1992.131","volume":"69","author":"CS Haley","year":"1992","unstructured":"Haley CS, Knott SA (1992) A simple regression method for mapping quantitative trait loci in line crosses using flanking markers. Heredity 69, 315\u2013324","journal-title":"Heredity"},{"key":"16_CR11","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1097\/01202412-199707000-00002","volume":"6","author":"JG Hall","year":"1997","unstructured":"Hall JG (1997) Arthrogryposis multiplex congenita: etiology, genetics, classification, diagnostic approach, and general aspects. J Pediatr Orthop B 6, 159\u2013166","journal-title":"J Pediatr Orthop B"},{"key":"16_CR12","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S1090-0233(02)00310-6","volume":"166","author":"CE Hostetler","year":"2003","unstructured":"Hostetler CE, Kincaid RL, Mirando MA (2003) The role of essential trace elements in embryonic and fetal development in livestock. Vet J 166, 125\u2013139","journal-title":"Vet J"},{"key":"16_CR13","doi-asserted-by":"crossref","DOI":"10.1016\/B978-0-08-057133-1.50010-2","volume-title":"Muscle and Tendon","author":"TJ Hulland","year":"1993","unstructured":"Hulland TJ (1993) Muscle and Tendon. (London: Academic Press)"},{"key":"16_CR14","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.1101\/gr.2741704","volume":"14","author":"N Ihara","year":"2004","unstructured":"Ihara N, Takasuga A, Mizoshita K, Takeda H, Sugimoto M, et al. (2004) A comprehensive genetic map of the cattle genome based on 3802 microsatellites. Genome Res 14, 1987\u20131998","journal-title":"Genome Res"},{"key":"16_CR15","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1210\/mend.16.5.0934","volume":"16","author":"JW Kim","year":"2002","unstructured":"Kim JW, Seghers V, Cho JH, Kang Y, Kim S, et al. (2002) Transactivation of the mouse sulfonylurea receptor I gene by BETA2\/NeuroD. Mol Endocrinol 16, 1097\u20131107","journal-title":"Mol Endocrinol"},{"key":"16_CR16","first-page":"426","volume":"60","author":"PA Krakowiak","year":"1997","unstructured":"Krakowiak PA, O\u2019Quinn JR, Bohnsack JF, Watkins WS, Carey JC, et al. (1997) A variant of Freeman-Sheldon syndrome maps to 11p15.5-pter. Am J Hum Genet 60, 426\u2013432","journal-title":"Am J Hum Genet"},{"key":"16_CR17","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1126\/science.7754368","volume":"268","author":"JE Lee","year":"1995","unstructured":"Lee JE, Hollenberg SM, Snider L, Turner DL, Lipnick N, et al. (1995) Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein. Science 268, 836\u2013844","journal-title":"Science"},{"key":"16_CR18","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1186\/BF03546542","volume":"26","author":"OM Lomo","year":"1985","unstructured":"Lomo OM, (1985) Arthrogryposis and associated defects in pigs: indication of simple recessive inheritance. Acta Vet Scand 26, 419\u2013422","journal-title":"Acta Vet Scand"},{"key":"16_CR19","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1152\/physrev.00042.2003","volume":"84","author":"JW Lynch","year":"2004","unstructured":"Lynch JW (2004) Molecular structure and function of the glycine receptor chloride channel. Physiol Rev 84, 1051\u20131095","journal-title":"Physiol Rev"},{"key":"16_CR20","volume-title":"Genetics and analysis of quantitative traits","author":"M Lynch","year":"1998","unstructured":"Lynch M, Walsh B (1998) Genetics and analysis of quantitative traits. (Sunderland, MA: Sinauer)"},{"key":"16_CR21","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1534\/genetics.104.039040","volume":"170","author":"DJ Lynn","year":"2005","unstructured":"Lynn DJ, Freeman AR, Murray C, Bradley DG (2005) A genomics approach to the detection of positive selection in cattle: adaptive evolution of the T-cell and natural killer cell-surface protein CD2. Genetics 170, 1189\u20131196","journal-title":"Genetics"},{"key":"16_CR22","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1093\/genetics\/146.3.1071","volume":"146","author":"DE MacHugh","year":"1997","unstructured":"MacHugh DE, Shriver MD, Loftus RT, Cunningham P, Bradley DG (1997) Microsatellite DNA variation and the evolution, domestication and phylogeography of taurine and zebu cattle (Bos taurus and Bos indicus). Genetics 146, 1071\u20131086","journal-title":"Genetics"},{"key":"16_CR23","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1101\/gr.GR-1350R","volume":"11","author":"JF Maddox","year":"2001","unstructured":"Maddox JF, Davies KP, Crawford AM, Hulme DJ, Vaiman D, et al. (2001) An enhanced linkage map of the sheep genome comprising more than 1000 loci. Genome Res 11, 1275\u20131289","journal-title":"Genome Res"},{"key":"16_CR24","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1177\/030098588402100210","volume":"21","author":"IG Mayhew","year":"1984","unstructured":"Mayhew IG (1984) Neuromuscular arthrogryposis multiplex congenita in a thoroughbred foal. Vet Pathol 21, 187\u2013192","journal-title":"Vet Pathol"},{"key":"16_CR25","first-page":"277","volume":"7","author":"NE Morton","year":"1955","unstructured":"Morton NE (1955) Sequential tests for the detection of linkage. Am J Hum Genet 7, 277\u2013318","journal-title":"Am J Hum Genet"},{"key":"16_CR26","unstructured":"Nettleton PF (1991) Border Disease. In: Martin WB, Aitken ID, eds. Diseases of sheep. (Oxford: Blackwell Scientific)"},{"key":"16_CR27","doi-asserted-by":"crossref","DOI":"10.56021\/9780801861406","volume-title":"Analysis of human genetic linkage","author":"J Ott","year":"1999a","unstructured":"Ott J (1999a) Analysis of human genetic linkage, 3rd ed. (Baltimore: The John Hopkins University Press)","edition":"3"},{"key":"16_CR28","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1093\/jhered\/90.1.68","volume":"90","author":"J Ott","year":"1999b","unstructured":"Ott J (1999b) Methods of analysis and resources available for genetic trait mapping. J Hered 90, 68\u201370","journal-title":"J Hered"},{"key":"16_CR29","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0378-4320(02)00162-8","volume":"74","author":"S Papadopoulos","year":"2002","unstructured":"Papadopoulos S, Rizos D, Duffy P, Wade M, Quinn K, et al. (2002) Embryo survival and recipient pregnancy rates after transfer of fresh or vitrified, in vivo or in vitro produced ovine blastocysts. Anim Reprod Sci 74, 35\u201344","journal-title":"Anim Reprod Sci"},{"key":"16_CR30","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0163-7258(96)00163-5","volume":"73","author":"S Rajendra","year":"1997","unstructured":"Rajendra S, Lynch JW, Schofield PR (1997) The glycine receptor. Pharmacol Ther 73, 121\u2013146","journal-title":"Pharmacol Ther"},{"key":"16_CR31","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/BF02983357","volume":"21","author":"JAF Roberts","year":"1929","unstructured":"Roberts JAF (1929) The inheritance of a lethal muscle contracture in sheep. J Genet 21, 57\u201369","journal-title":"J Genet"},{"key":"16_CR32","volume-title":"Molecular cloning: a laboratory manual","author":"J Sambrook","year":"2001","unstructured":"Sambrook J, Russell DW (2001) Molecular cloning: a laboratory manual. (Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press)"},{"key":"16_CR33","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1038\/72708","volume":"18","author":"M Schuelke","year":"2000","unstructured":"Schuelke M (2000) An economic method for the fluorescent labeling of PCR fragments. Nat Biotechnol 18, 233\u2013234","journal-title":"Nat Biotechnol"},{"key":"16_CR34","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1093\/bioinformatics\/18.2.339","volume":"18","author":"G Seaton","year":"2002","unstructured":"Seaton G, Haley CS, Knott SA, Kearsey M, Visscher PM (2002) QTL Express: mapping quantitative trait loci in simple and complex pedigrees. Bioinformatics 18, 339\u2013340","journal-title":"Bioinformatics"},{"key":"16_CR35","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1086\/301598","volume":"61","author":"M Shohat","year":"1997","unstructured":"Shohat M, Lotan R, Magal N, Shohat T, Fischel-Ghodsian N, et al. (1997) A gene for arthrogryposis multiplex congenita neuropathic type is linked to D5S394 on chromosome 5qter. Am J Hum Genet 61, 1139\u20131143","journal-title":"Am J Hum Genet"},{"key":"16_CR36","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S0092-8674(01)00224-0","volume":"104","author":"Y Sun","year":"2001","unstructured":"Sun Y, Nadal-Vicens M, Misono S, Lin MZ, Zubiaga A, et al. (2001) Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms. Cell 104, 365\u2013376","journal-title":"Cell"},{"key":"16_CR37","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1086\/368294","volume":"72","author":"SS Sung","year":"2003a","unstructured":"Sung SS, Brassington AM, Grannatt K, Rutherford A, Whitby FG, et al. (2003a) Mutations in genes encoding fast-twitch contractile proteins cause distal arthrogryposis syndromes. Am J Hum Genet 72, 681\u2013690","journal-title":"Am J Hum Genet"},{"key":"16_CR38","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1086\/376418","volume":"73","author":"SS Sung","year":"2003b","unstructured":"Sung SS, Brassington AM, Krakowiak PA, Carey JC, Jorde LB, et al. (2003b) Mutations in TNNT3 cause multiple congenital contractures: a second locus for distal arthrogryposis type 2B. Am J Hum Genet 73, 212\u2013214","journal-title":"Am J Hum Genet"},{"key":"16_CR39","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1002\/ajmg.10030","volume":"104","author":"MG Tanamy","year":"2001","unstructured":"Tanamy MG, Magal N, Halpern GJ, Jaber L, Shohat M (2001) Fine mapping places the gene for arthrogryposis multiplex congenita neuropathic type between D5S394 and D5S2069 on chromosome 5qter. Am J Med Genet 104, 152\u2013156","journal-title":"Am J Med Genet"},{"key":"16_CR40","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/BF00362806","volume":"12","author":"X Huffel Van","year":"1988","unstructured":"Van Huffel X, Weyns A, Van Nassauw L, Cockelbergh D, De Moor A (1988) Decreased number of alpha-motoneurons in the cervical intumescence of calves with arthrogryposis multiplex congenita of both thoracic limbs. Vet Res Commun 12, 237\u2013243","journal-title":"Vet Res Commun"},{"key":"16_CR41","doi-asserted-by":"crossref","first-page":"D39","DOI":"10.1093\/nar\/gki062","volume":"33","author":"DL Wheeler","year":"2005","unstructured":"Wheeler DL, Barrett T, Benson DA, Bryant SH, Canese K, et al. (2005) Database resources of the National Center for Biotechnology Information. Nucleic Acids Res 33, D39\u201345","journal-title":"Nucleic Acids Res"}],"container-title":["Mammalian Genome"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00335-006-0016-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00335-006-0016-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00335-006-0016-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T13:14:35Z","timestamp":1683724475000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00335-006-0016-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,1]]},"references-count":41,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,1]]}},"alternative-id":["16"],"URL":"https:\/\/doi.org\/10.1007\/s00335-006-0016-8","relation":{},"ISSN":["0938-8990","1432-1777"],"issn-type":[{"value":"0938-8990","type":"print"},{"value":"1432-1777","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,1]]}}}