{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T14:05:27Z","timestamp":1761919527473,"version":"3.38.0"},"reference-count":63,"publisher":"Springer Science and Business Media LLC","issue":"5-6","license":[{"start":{"date-parts":[[2011,12,30]],"date-time":"2011-12-30T00:00:00Z","timestamp":1325203200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mamm Genome"],"published-print":{"date-parts":[[2012,6]]},"DOI":"10.1007\/s00335-011-9385-8","type":"journal-article","created":{"date-parts":[[2011,12,29]],"date-time":"2011-12-29T06:33:18Z","timestamp":1325140398000},"page":"322-335","source":"Crossref","is-referenced-by-count":28,"title":["Genome-wide association mapping of loci for antipsychotic-induced extrapyramidal symptoms in mice"],"prefix":"10.1007","volume":"23","author":[{"given":"James J.","family":"Crowley","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunjung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin Peng","family":"Szatkiewicz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda L.","family":"Pratt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corey R.","family":"Quackenbush","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel E.","family":"Adkins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edwin","family":"van den Oord","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Molly A.","family":"Bogue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyuna","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David W.","family":"Threadgill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando Pardo-Manuel","family":"de Villena","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Howard L.","family":"McLeod","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick F.","family":"Sullivan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,12,30]]},"reference":[{"key":"9385_CR1","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.biopsych.2009.08.036","volume":"67","author":"K Aberg","year":"2010","unstructured":"Aberg K, Adkins DE, Bukszar J, Webb BT, Caroff SN, Miller del D, Sebat J, Stroup S, Fanous AH, Vladimirov VI, McClay JL, Lieberman JA, Sullivan PF, van den Oord EJ (2010) Genomewide association study of movement-related adverse antipsychotic effects. Biol Psychiatry 67:279\u2013282","journal-title":"Biol Psychiatry"},{"issue":"8","key":"9385_CR2","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1101\/gr.111310.110","volume":"21","author":"DL Aylor","year":"2011","unstructured":"Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, Baric RS, Ferris MT, Frelinger JA, Heise M, Frieman MB, Gralinski LE, Bell TA, Didion JD, Hua K, Nehrenberg DL, Powell CL, Steigerwalt J, Xie Y, Kelada SN, Collins FS, Yang IV, Schwartz DA, Branstetter LA, Chesler EJ, Miller DR, Spence J, Liu EY, McMillan L, Sarkar A, Wang J, Wang W, Zhang Q, Broman KW, Korstanje R, Durrant C, Mott R, Iraqi FA, Pomp D, Threadgill D, Pardo-Manuel de Villena F, Churchill GA (2011) Genetic analysis of complex traits in the emerging collaborative cross. Genome Res 21(8):1213\u20131222","journal-title":"Genome Res"},{"key":"9385_CR3","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.schres.2006.01.010","volume":"83","author":"PR Bakker","year":"2006","unstructured":"Bakker PR, van Harten PN, van Os J (2006) Antipsychotic-induced tardive dyskinesia and the Ser9Gly polymorphism in the DRD3 gene: a meta analysis. Schizophr Res 83:185\u2013192","journal-title":"Schizophr Res"},{"key":"9385_CR4","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/0091-3057(90)90094-X","volume":"36","author":"DE Barnes","year":"1990","unstructured":"Barnes DE, Robinson B, Csernansky JG, Bellows EP (1990) Sensitization versus tolerance to haloperidol-induced catalepsy: multiple determinants. Pharmacol Biochem Behav 36:883\u2013887","journal-title":"Pharmacol Biochem Behav"},{"key":"9385_CR5","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1093\/bioinformatics\/bti260","volume":"21","author":"WT Barry","year":"2005","unstructured":"Barry WT, Nobel AB, Wright FA (2005) Significance analysis of functional categories in gene expression studies: a structured permutation approach. Bioinformatics 21:1943\u20131949","journal-title":"Bioinformatics"},{"key":"9385_CR6","doi-asserted-by":"crossref","first-page":"D842","DOI":"10.1093\/nar\/gkq1008","volume":"39","author":"JA Blake","year":"2011","unstructured":"Blake JA, Bult CJ, Kadin JA, Richardson JE, Eppig JT (2011) The Mouse Genome Database (MGD): premier model organism resource for mammalian genomics and genetics. Nucleic Acids Res 39:D842\u2013D848","journal-title":"Nucleic Acids Res"},{"key":"9385_CR7","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s10709-004-1438-4","volume":"122","author":"MA Bogue","year":"2004","unstructured":"Bogue MA, Grubb SC (2004) The mouse phenome project. Genetica 122:71\u201374","journal-title":"Genetica"},{"key":"9385_CR8","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1002\/syn.20825","volume":"65","author":"S Chen","year":"2011","unstructured":"Chen S, Seeman P, Liu F (2011) Antipsychotic drug binding in the substantia nigra: an examination of high metoclopramide binding in the brains of normal, Alzheimer\u2019s disease, Huntington\u2019s disease, and Multiple Sclerosis patients, and its relation to tardive dyskinesia. Synapse 65:119\u2013124","journal-title":"Synapse"},{"key":"9385_CR9","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/S0022-3565(25)13263-1","volume":"247","author":"RE Chipkin","year":"1988","unstructured":"Chipkin RE, Iorio LC, Coffin VL, McQuade RD, Berger JG, Barnett A (1988) Pharmacological profile of SCH39166: a dopamine D1 selective benzonaphthazepine with potential antipsychotic activity. J Pharmacol Exp Ther 247:1093\u20131102","journal-title":"J Pharmacol Exp Ther"},{"key":"9385_CR10","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1038\/ng1104-1133","volume":"36","author":"GA Churchill","year":"2004","unstructured":"Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD, Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ, Buckler E, Burmeister M, Chesler EJ, Cheverud JM, Clapcote S, Cook MN, Cox RD, Crabbe JC, Crusio WE, Darvasi A, Deschepper CF, Doerge RW, Farber CR, Forejt J, Gaile D, Garlow SJ, Geiger H, Gershenfeld H, Gordon T, Gu J, Gu W, de Haan G, Hayes NL, Heller C, Himmelbauer H, Hitzemann R, Hunter K, Hsu HC, Iraqi FA, Ivandic B, Jacob HJ, Jansen RC, Jepsen KJ, Johnson DK, Johnson TE, Kempermann G, Kendziorski C, Kotb M, Kooy RF, Llamas B, Lammert F, Lassalle JM, Lowenstein PR, Lu L, Lusis A, Manly KF, Marcucio R, Matthews D, Medrano JF, Miller DR, Mittleman G, Mock BA, Mogil JS, Montagutelli X, Morahan G, Morris DG, Mott R, Nadeau JH, Nagase H, Nowakowski RS, O\u2019Hara BF, Osadchuk AV, Page GP, Paigen B, Paigen K, Palmer AA, Pan HJ, Peltonen-Palotie L, Peirce J, Pomp D, Pravenec M, Prows DR, Qi Z, Reeves RH, Roder J, Rosen GD, Schadt EE, Schalkwyk LC, Seltzer Z, Shimomura K, Shou S, Sillanpaa MJ, Siracusa LD, Snoeck HW, Spearow JL, Svenson K, Tarantino LM, Threadgill D, Toth LA, Valdar W, de Villena FP, Warden C, Whatley S, Williams RW, Wiltshire T, Yi N, Zhang D, Zhang M, Zou F (2004) The collaborative cross, a community resource for the genetic analysis of complex traits. Nat Genet 36:1133\u20131137","journal-title":"Nat Genet"},{"issue":"Suppl","key":"9385_CR11","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1176\/ajp.124.8S.40","volume":"124","author":"GE Crane","year":"1968","unstructured":"Crane GE (1968) Tardive dyskinesia in patients treated with major neuroleptics: a review of the literature. Am J Psychiatry 124(Suppl):40\u201348","journal-title":"Am J Psychiatry"},{"key":"9385_CR12","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0149-7634(85)90030-2","volume":"9","author":"JN Crawley","year":"1985","unstructured":"Crawley JN (1985) Exploratory behavior models of anxiety in mice. Neurosci Biobehav Rev 9:37\u201344","journal-title":"Neurosci Biobehav Rev"},{"key":"9385_CR13","doi-asserted-by":"crossref","unstructured":"Crowley JJ, Adkins DE, Pratt AL, Quackenbush CR, van den Oord EJ, Moy SS, Wilhelmsen KC, Cooper TB, Bogue MA, McLeod HL, Sullivan PF (2010) Antipsychotic-induced vacuous chewing movements and extrapyramidal side effects are highly heritable in mice. Pharmacogenomics J. doi: 10.1038\/tpj.2010.82","DOI":"10.1038\/tpj.2010.82"},{"key":"9385_CR14","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1517\/14656566.9.9.1451","volume":"9","author":"P Dayalu","year":"2008","unstructured":"Dayalu P, Chou KL (2008) Antipsychotic-induced extrapyramidal symptoms and their management. Expert Opin Pharmacother 9:1451\u20131462","journal-title":"Expert Opin Pharmacother"},{"key":"9385_CR15","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1007\/BF02245788","volume":"100","author":"ND Eddington","year":"1990","unstructured":"Eddington ND, Young D (1990) Biliary excretion of reduced haloperidol glucuronide. Psychopharmacology 100:46\u201348","journal-title":"Psychopharmacology"},{"key":"9385_CR16","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1016\/S0022-5347(05)64637-X","volume":"168","author":"N Fleischmann","year":"2002","unstructured":"Fleischmann N, Christ G, Sclafani T, Melman A (2002) The effect of ovariectomy and long-term estrogen replacement on bladder structure and function in the rat. J Urol 168:1265\u20131268","journal-title":"J Urol"},{"key":"9385_CR17","doi-asserted-by":"crossref","first-page":"396","DOI":"10.2165\/00003088-198917060-00004","volume":"17","author":"JS Froemming","year":"1989","unstructured":"Froemming JS, Lam YW, Jann MW, Davis CM (1989) Pharmacokinetics of haloperidol. Clin Pharmacokinet 17:396\u2013423","journal-title":"Clin Pharmacokinet"},{"key":"9385_CR18","doi-asserted-by":"crossref","first-page":"D876","DOI":"10.1093\/nar\/gkq963","volume":"39","author":"PA Fujita","year":"2011","unstructured":"Fujita PA, Rhead B, Zweig AS, Hinrichs AS, Karolchik D, Cline MS, Goldman M, Barber GP, Clawson H, Coelho A, Diekhans M, Dreszer TR, Giardine BM, Harte RA, Hillman-Jackson J, Hsu F, Kirkup V, Kuhn RM, Learned K, Li CH, Meyer LR, Pohl A, Raney BJ, Rosenbloom KR, Smith KE, Haussler D, Kent WJ (2011) The UCSC Genome Browser database: update 2011. Nucleic Acids Res 39:D876\u2013D882","journal-title":"Nucleic Acids Res"},{"key":"9385_CR19","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1007\/s007020070089","volume":"107","author":"R Galili","year":"2000","unstructured":"Galili R, Mosberg Gil-AdI, Weizman A, Melamed E, Offen D (2000) Haloperidol-induced neurotoxicity\u2013possible implications for tardive dyskinesia. J Neural Transm 107:479\u2013490","journal-title":"J Neural Transm"},{"key":"9385_CR20","volume-title":"Variance Components","author":"H Goldstein","year":"1995","unstructured":"Goldstein H (1995) Multilevel statistical models. In: Searle S, Casella G, McCulloch C (eds) Variance Components. Wiley, New York"},{"key":"9385_CR21","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1101\/gr.090241.108","volume":"19","author":"AH Harrill","year":"2009","unstructured":"Harrill AH, Watkins PB, Su S, Ross PK, Harbourt DE, Stylianou IM, Boorman GA, Russo MW, Sackler RS, Harris SC, Smith PC, Tennant R, Bogue M, Paigen K, Harris C, Contractor T, Wiltshire T, Rusyn I, Threadgill DW (2009) Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans. Genome Res 19:1507\u20131515","journal-title":"Genome Res"},{"key":"9385_CR22","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0924-9338(03)00005-1","volume":"18","author":"H Herken","year":"2003","unstructured":"Herken H, Erdal ME, Boke O, Savas HA (2003) Tardive dyskinesia is not associated with the polymorphisms of 5-HT2A receptor gene, serotonin transporter gene and catechol-o-methyltransferase gene. Eur Psychiatry 18:77\u201381","journal-title":"Eur Psychiatry"},{"key":"9385_CR23","first-page":"2265","volume-title":"Medication-induced movement disorders. In: Kaplan and Sadocks\u2019s Comprehensive Textbook of Psychiatry","author":"E Hsin-tung","year":"2000","unstructured":"Hsin-tung E, Simpson G (2000) Medication-induced movement disorders. In: Kaplan and Sadocks\u2019s Comprehensive Textbook of Psychiatry. Lippincott, Williams and Wilkins, Philadelphia, pp 2265\u20132271"},{"key":"9385_CR24","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1093\/bioinformatics\/btl048","volume":"22","author":"F Hsu","year":"2006","unstructured":"Hsu F, Kent WJ, Clawson H, Kuhn RM, Diekhans M, Haussler D (2006) The UCSC known genes. Bioinformatics 22:1036\u20131046","journal-title":"Bioinformatics"},{"key":"9385_CR25","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.biopsych.2009.08.030","volume":"67","author":"M Ikeda","year":"2010","unstructured":"Ikeda M, Tomita Y, Mouri A, Koga M, Okochi T, Yoshimura R, Yamanouchi Y, Kinoshita Y, Hashimoto R, Williams HJ, Takeda M, Nakamura J, Nabeshima T, Owen MJ, O\u2019Donovan MC, Honda H, Arinami T, Ozaki N, Iwata N (2010) Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches. Biol Psychiatry 67:263\u2013269","journal-title":"Biol Psychiatry"},{"key":"9385_CR26","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/BF02289343","volume":"34","author":"K Joreskog","year":"1969","unstructured":"Joreskog K (1969) A general approach to confirmatory maximum likelihood factor analysis. Psychometrika 34:183\u2013202","journal-title":"Psychometrika"},{"key":"9385_CR27","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1038\/sj.mp.4001054","volume":"7","author":"R Kaiser","year":"2002","unstructured":"Kaiser R, Tremblay PB, Klufmoller F, Roots I, Brockmoller J (2002) Relationship between adverse effects of antipsychotic treatment and dopamine D(2) receptor polymorphisms in patients with schizophrenia. Mol Psychiatry 7:695\u2013705","journal-title":"Mol Psychiatry"},{"key":"9385_CR28","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1534\/genetics.107.080101","volume":"178","author":"HM Kang","year":"2008","unstructured":"Kang HM, Zaitlen NA, Wade CM, Kirby A, Heckerman D, Daly MJ, Eskin E (2008) Efficient control of population structure in model organism association mapping. Genetics 178:1709\u20131723","journal-title":"Genetics"},{"key":"9385_CR29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/B978-0-12-385198-7.00001-1","volume":"97","author":"N Koshikawa","year":"2011","unstructured":"Koshikawa N, Fujita S, Adachi K (2011) Behavioral pharmacology of orofacial movement disorders. Int Rev Neurobiol 97:1\u201338","journal-title":"Int Rev Neurobiol"},{"key":"9385_CR30","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1186\/1423-0127-17-91","volume":"17","author":"E Lagrue","year":"2010","unstructured":"Lagrue E, Abe H, Lavanya M, Touhami J, Bodard S, Chalon S, Battini JL, Sitbon M, Castelnau P (2010) Regional characterization of energy metabolism in the brain of normal and MPTP-intoxicated mice using new markers of glucose and phosphate transport. J Biomed Sci 17:91","journal-title":"J Biomed Sci"},{"key":"9385_CR31","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1007\/s00702-004-0252-6","volume":"112","author":"IC Lai","year":"2005","unstructured":"Lai IC, Wang YC, Lin CC, Bai YM, Liao DL, Yu SC, Lin CY, Chen JY, Liou YJ (2005) Negative association between catechol-O-methyltransferase (COMT) gene Val158Met polymorphism and persistent tardive dyskinesia in schizophrenia. J Neural Transm 112:1107\u20131113","journal-title":"J Neural Transm"},{"key":"9385_CR32","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1159\/000103576","volume":"55","author":"HJ Lee","year":"2007","unstructured":"Lee HJ, Kang SG, Choi JE, Paik JW, Kim YK, Kim SH, Lee MS, Joe SH, Jung IK, Kim L (2007) No association between dopamine D4 receptor gene -521 C\/T polymorphism and tardive dyskinesia in schizophrenia. Neuropsychobiology 55:47\u201351","journal-title":"Neuropsychobiology"},{"key":"9385_CR33","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1017\/S1461145705005389","volume":"8","author":"B Lerer","year":"2005","unstructured":"Lerer B, Segman RH, Tan EC, Basile VS, Cavallaro R, Aschauer HN, Strous R, Chong SA, Heresco-Levy U, Verga M, Scharfetter J, Meltzer HY, Kennedy JL, Macciardi F (2005) Combined analysis of 635 patients confirms an age-related association of the serotonin 2A receptor gene with tardive dyskinesia and specificity for the non-orofacial subtype. Int J Neuropsychopharmacol 8:411\u2013425","journal-title":"Int J Neuropsychopharmacol"},{"key":"9385_CR34","doi-asserted-by":"crossref","first-page":"4353","DOI":"10.1073\/pnas.91.10.4353","volume":"91","author":"MS Lidow","year":"1994","unstructured":"Lidow MS, Goldman-Rakic PS (1994) A common action of clozapine, haloperidol, and remoxipride on D1- and D2-dopaminergic receptors in the primate cerebral cortex. Proc Natl Acad Sci USA 91:4353\u20134356","journal-title":"Proc Natl Acad Sci USA"},{"key":"9385_CR35","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1038\/nrg2612","volume":"10","author":"TF Mackay","year":"2009","unstructured":"Mackay TF, Stone EA, Ayroles JF (2009) The genetics of quantitative traits: challenges and prospects. Nat Rev Genet 10:565\u2013577","journal-title":"Nat Rev Genet"},{"key":"9385_CR36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.psychres.2004.03.011","volume":"127","author":"C Matsumoto","year":"2004","unstructured":"Matsumoto C, Shinkai T, Hori H, Ohmori O, Nakamura J (2004) Polymorphisms of dopamine degradation enzyme (COMT and MAO) genes and tardive dyskinesia in patients with schizophrenia. Psychiatry Res 127:1\u20137","journal-title":"Psychiatry Res"},{"key":"9385_CR37","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1086\/514346","volume":"80","author":"VA McKusick","year":"2007","unstructured":"McKusick VA (2007) Mendelian inheritance in man and its online version, OMIM. Am J Hum Genet 80:588\u2013604","journal-title":"Am J Hum Genet"},{"key":"9385_CR38","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0306-4522(01)00455-9","volume":"109","author":"IJ Mitchell","year":"2002","unstructured":"Mitchell IJ, Cooper AC, Griffiths MR, Cooper AJ (2002) Acute administration of haloperidol induces apoptosis of neurones in the striatum and substantia nigra in the rat. Neuroscience 109:89\u201399","journal-title":"Neuroscience"},{"key":"9385_CR39","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/S0092-8674(00)81972-8","volume":"98","author":"AR Mohn","year":"1999","unstructured":"Mohn AR, Gainetdinov RR, Caron MG, Koller BH (1999) Mice with reduced NMDA receptor expression display behaviors related to schizophrenia. Cell 98:427\u2013436","journal-title":"Cell"},{"key":"9385_CR40","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1034\/j.1600-0447.2001.00401.x","volume":"104","author":"DJ Muller","year":"2001","unstructured":"Muller DJ, Schulze TG, Knapp M, Held T, Krauss H, Weber T, Ahle G, Maroldt A, Alfter D, Maier W, Nothen MM, Rietschel M (2001) Familial occurrence of tardive dyskinesia. Acta Psychiatr Scand 104:375\u2013379","journal-title":"Acta Psychiatr Scand"},{"key":"9385_CR41","volume-title":"Traditional latent variable modeling using Mplus: Mplus Short course notes","author":"B Muth\u00e9n","year":"2003","unstructured":"Muth\u00e9n B, Muth\u00e9n L (2003) Traditional latent variable modeling using Mplus: Mplus Short course notes. Muth\u00e9n & Muth\u00e9n, Los Angeles"},{"key":"9385_CR42","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1192\/bjp.157.4.578","volume":"157","author":"E O\u2019Callaghan","year":"1990","unstructured":"O\u2019Callaghan E, Larkin C, Kinsella A, Waddington JL (1990) Obstetric complications, the putative familial-sporadic distinction, and tardive dyskinesia in schizophrenia. Br J Psychiatry 157:578\u2013584","journal-title":"Br J Psychiatry"},{"key":"9385_CR43","unstructured":"Pan F, McMillan L, Pardo-Manuel De Villena F, Threadgill D, Wang W (2009) TreeQA: quantitative genome wide association mapping using local perfect phylogeny trees. Pac Symp Biocomput 415\u2013426"},{"key":"9385_CR44","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1097\/01213011-200503000-00003","volume":"15","author":"NA Patsopoulos","year":"2005","unstructured":"Patsopoulos NA, Ntzani EE, Zintzaras E, Ioannidis JP (2005) CYP2D6 polymorphisms and the risk of tardive dyskinesia in schizophrenia: a meta-analysis. Pharmacogenet Genomics 15:151\u2013158","journal-title":"Pharmacogenet Genomics"},{"key":"9385_CR45","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1113\/jphysiol.2006.113464","volume":"575","author":"N Prakash","year":"2006","unstructured":"Prakash N, Wurst W (2006) Genetic networks controlling the development of midbrain dopaminergic neurons. J Physiol 575:403\u2013410","journal-title":"J Physiol"},{"key":"9385_CR46","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/j.pnpbp.2005.03.019","volume":"29","author":"GP Reynolds","year":"2005","unstructured":"Reynolds GP, Templeman LA, Zhang ZJ (2005) The role of 5-HT2C receptor polymorphisms in the pharmacogenetics of antipsychotic drug treatment. Prog Neuropsychopharmacol Biol Psychiatry 29:1021\u20131028","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"9385_CR47","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.2217\/pgs.10.100","volume":"11","author":"I Rusyn","year":"2010","unstructured":"Rusyn I, Gatti DM, Wiltshire T, Kleeberger SR, Threadgill DW (2010) Toxicogenetics: population-based testing of drug and chemical safety in mouse models. Pharmacogenomics 11:1127\u20131136","journal-title":"Pharmacogenomics"},{"key":"9385_CR48","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/373151a0","volume":"373","author":"K Sakimura","year":"1995","unstructured":"Sakimura K, Kutsuwada T, Ito I, Manabe T, Takayama C, Kushiya E, Yagi T, Aizawa S, Inoue Y, Sugiyama H et al (1995) Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit. Nature 373:151\u2013155","journal-title":"Nature"},{"key":"9385_CR49","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1038\/mp.2008.20","volume":"13","author":"G Shaltiel","year":"2008","unstructured":"Shaltiel G, Maeng S, Malkesman O, Pearson B, Schloesser RJ, Tragon T, Rogawski M, Gasior M, Luckenbaugh D, Chen G, Manji HK (2008) Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania. Mol Psychiatry 13:858\u2013872","journal-title":"Mol Psychiatry"},{"issue":"Suppl","key":"9385_CR50","first-page":"12","volume":"31","author":"GM Simpson","year":"1970","unstructured":"Simpson GM (1970) Long-acting, antipsychotic agents and extrapyramidal side effects. Dis Nerv Syst 31(Suppl):12\u201314","journal-title":"Dis Nerv Syst"},{"key":"9385_CR51","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1007\/s10495-006-5698-6","volume":"11","author":"KJ Skoblenick","year":"2006","unstructured":"Skoblenick KJ, Castellano JM, Rogoza RM, Dyck BA, Thomas N, Gabriele JP, Chong VZ, Mishra RK (2006) Translocation of AIF in the human and rat striatum following protracted haloperidol, but not clozapine treatment. Apoptosis 11:663\u2013672","journal-title":"Apoptosis"},{"key":"9385_CR52","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1055\/s-2007-971169","volume":"27","author":"K Soares-Weiser","year":"2007","unstructured":"Soares-Weiser K, Fernandez HH (2007) Tardive dyskinesia. Semin Neurol 27:159\u2013169","journal-title":"Semin Neurol"},{"key":"9385_CR53","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.schres.2007.11.033","volume":"100","author":"R Tandon","year":"2008","unstructured":"Tandon R, Belmaker RH, Gattaz WF, Lopez-Ibor JJ Jr, Okasha A, Singh B, Stein DJ, Olie JP, Fleischhacker WW, Moeller HJ (2008) World Psychiatric Association Pharmacopsychiatry Section statement on comparative effectiveness of antipsychotics in the treatment of schizophrenia. Schizophr Res 100:20\u201338","journal-title":"Schizophr Res"},{"key":"9385_CR54","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0014-2999(01)00908-6","volume":"418","author":"K Tomiyama","year":"2001","unstructured":"Tomiyama K, McNamara FN, Clifford JJ, Kinsella A, Koshikawa N, Waddington JL (2001) Topographical assessment and pharmacological characterization of orofacial movements in mice: dopamine D(1)-like vs. D(2)-like receptor regulation. Eur J Pharmacol 418:47\u201354","journal-title":"Eur J Pharmacol"},{"key":"9385_CR55","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0149-7634(02)00008-8","volume":"26","author":"P Turrone","year":"2002","unstructured":"Turrone P, Remington G, Nobrega JN (2002) The vacuous chewing movement (VCM) model of tardive dyskinesia revisited: is there a relationship to dopamine D(2) receptor occupancy? Neurosci Biobehav Rev 26:361\u2013380","journal-title":"Neurosci Biobehav Rev"},{"key":"9385_CR56","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1007\/s00213-002-1259-z","volume":"165","author":"P Turrone","year":"2003","unstructured":"Turrone P, Remington G, Kapur S, Nobrega JN (2003) The relationship between dopamine D2 receptor occupancy and the vacuous chewing movement syndrome in rats. Psychopharmacology (Berl) 165:166\u2013171","journal-title":"Psychopharmacology (Berl)"},{"key":"9385_CR57","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1177\/00131640121971518","volume":"51","author":"J Prooijen Van","year":"2001","unstructured":"Van Prooijen J, Van Der Kloot WA (2001) Confirmatory analysis of exploratively obtained factor structures. Educ Psychol Measure 51:777\u2013792","journal-title":"Educ Psychol Measure"},{"key":"9385_CR58","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1038\/nn.2329","volume":"12","author":"GM Woerden van","year":"2009","unstructured":"van Woerden GM, Hoebeek FE, Gao Z, Nagaraja RY, Hoogenraad CC, Kushner SA, Hansel C, De Zeeuw CI, Elgersma Y (2009) betaCaMKII controls the direction of plasticity at parallel fiber-Purkinje cell synapses. Nat Neurosci 12:823\u2013825","journal-title":"Nat Neurosci"},{"key":"9385_CR59","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1126\/science.6132447","volume":"220","author":"JL Waddington","year":"1983","unstructured":"Waddington JL, Cross AJ, Gamble SJ, Bourne RC (1983) Spontaneous orofacial dyskinesia and dopaminergic function in rats after 6\u00a0months of neuroleptic treatment. Science 220:530\u2013532","journal-title":"Science"},{"key":"9385_CR60","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1101\/gr.6861907","volume":"17","author":"K Wang","year":"2007","unstructured":"Wang K, Li M, Hadley D, Liu R, Glessner J, Grant SF, Hakonarson H, Bucan M (2007) PennCNV: an integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data. Genome Res 17:1665\u20131674","journal-title":"Genome Res"},{"key":"9385_CR61","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1038\/nmeth.1359","volume":"6","author":"H Yang","year":"2009","unstructured":"Yang H, Ding Y, Hutchins LN, Szatkiewicz J, Bell TA, Paigen BJ, Graber JH, de Villena FP, Churchill GA (2009) A customized and versatile high-density genotyping array for the mouse. Nat Methods 6:663\u2013666","journal-title":"Nat Methods"},{"key":"9385_CR62","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1176\/ajp.138.12.1618","volume":"138","author":"R Yassa","year":"1981","unstructured":"Yassa R, Ananth J (1981) Familial tardive dyskinesia. Am J Psychiatry 138:1618\u20131619","journal-title":"Am J Psychiatry"},{"key":"9385_CR63","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1038\/ncb2057","volume":"12","author":"Y Zaltsman","year":"2010","unstructured":"Zaltsman Y, Shachnai L, Yivgi-Ohana N, Schwarz M, Maryanovich M, Houtkooper RH, Vaz FM, De Leonardis F, Fiermonte G, Palmieri F, Gillissen B, Daniel PT, Jimenez E, Walsh S, Koehler CM, Roy SS, Walter L, Hajnoczky G, Gross A (2010) MTCH2\/MIMP is a major facilitator of tBID recruitment to mitochondria. Nat Cell Biol 12:553\u2013562","journal-title":"Nat Cell Biol"}],"container-title":["Mammalian Genome"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00335-011-9385-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00335-011-9385-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00335-011-9385-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T01:15:02Z","timestamp":1742174102000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00335-011-9385-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12,30]]},"references-count":63,"journal-issue":{"issue":"5-6","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["9385"],"URL":"https:\/\/doi.org\/10.1007\/s00335-011-9385-8","relation":{},"ISSN":["0938-8990","1432-1777"],"issn-type":[{"type":"print","value":"0938-8990"},{"type":"electronic","value":"1432-1777"}],"subject":[],"published":{"date-parts":[[2011,12,30]]}}}