{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T23:53:06Z","timestamp":1772754786406,"version":"3.50.1"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"7-8","license":[{"start":{"date-parts":[[2013,8,1]],"date-time":"2013-08-01T00:00:00Z","timestamp":1375315200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mamm Genome"],"published-print":{"date-parts":[[2013,8]]},"DOI":"10.1007\/s00335-013-9470-2","type":"journal-article","created":{"date-parts":[[2013,8,8]],"date-time":"2013-08-08T00:54:53Z","timestamp":1375923293000},"page":"295-302","source":"Crossref","is-referenced-by-count":13,"title":["Lens density tracking in mice by Scheimpflug imaging"],"prefix":"10.1007","volume":"24","author":[{"given":"Oliver","family":"Puk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin Hrab\u0115","family":"de Angelis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jochen","family":"Graw","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,8,9]]},"reference":[{"key":"9470_CR1","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1167\/iovs.03-0677","volume":"45","author":"A Alizadeh","year":"2004","unstructured":"Alizadeh A, Clark J, Seeberger T, Hess J, Blankenship T, FitzGerald PG (2004) Characterization of a mutation in the lens-specific CP49 in the 129 strain of mouse. Invest Ophthalmol Vis Sci 45:884\u2013891","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"9470_CR2","doi-asserted-by":"crossref","first-page":"284","DOI":"10.3341\/kjo.2010.24.5.284","volume":"24","author":"YK Cho","year":"2010","unstructured":"Cho YK, Chang HS, La TY, Ji D, Kim H, Choi JA, Kim MS (2010) Anterior segment parameters using Pentacam and prediction of corneal endothelial cell loss after cataract surgery. Korean J Ophthalmol 24:284\u2013290","journal-title":"Korean J Ophthalmol"},{"key":"9470_CR3","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1098\/rstb.2010.0227","volume":"366","author":"A Churchill","year":"2011","unstructured":"Churchill A, Graw J (2011) Clinical and experimental advances in congenital and paediatric cataracts. Philos Trans R Soc Lond B Biol Sci 366:1234\u20131249","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"9470_CR4","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1002\/9783527611942.ch12","volume-title":"Standards of mouse model phenotyping","author":"C Dalke","year":"2006","unstructured":"Dalke C, Puk O, Neuh\u00e4user-Klaus A, Favor J, Graw J (2006) Eye disorders. In: Hrab\u0115 de Angelis M, Chambon P, Brown S (eds) Standards of mouse model phenotyping. Wiley, Weinheim, pp 283\u2013309"},{"key":"9470_CR5","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.ymeth.2010.08.006","volume":"53","author":"H Fuchs","year":"2011","unstructured":"Fuchs H, Gailus-Durner V, Adler T, Aguilar-Pimentel JA, Becker L et al (2011) Mouse phenotyping. Methods 53:120\u2013135","journal-title":"Methods"},{"key":"9470_CR6","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1007\/s12041-009-0066-2","volume":"88","author":"J Graw","year":"2009","unstructured":"Graw J (2009) Mouse models of cataract. J Genet 88:469\u2013486","journal-title":"J Genet"},{"key":"9470_CR7","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1016\/j.ophtha.2009.03.002","volume":"116","author":"DS Grewal","year":"2009","unstructured":"Grewal DS, Brar GS, Grewal SP (2009) Correlation of nuclear cataract lens density using Scheimpflug images with Lens Opacities Classification System III and visual function. Ophthalmology 116:1436\u20131443","journal-title":"Ophthalmology"},{"key":"9470_CR8","doi-asserted-by":"crossref","first-page":"11579","DOI":"10.1074\/jbc.M110.148627","volume":"286","author":"R Gupta","year":"2011","unstructured":"Gupta R, Asomugha CO, Srivastava OP (2011) The common modification in alphaA-crystallin in the lens, N101D, is associated with increased opacity in a mouse model. J Biol Chem 286:11579\u201311592","journal-title":"J Biol Chem"},{"key":"9470_CR9","first-page":"3","volume-title":"The epidemiology of eye disease","author":"GJ Johnson","year":"2004","unstructured":"Johnson GJ, Foster A (2004) Prevalence, incidence and distribution of visual impairment. In: Johnson GJ, Minassian DC, Weale RA, West SK (eds) The epidemiology of eye disease. Arnold, London, pp 3\u201328"},{"key":"9470_CR10","doi-asserted-by":"crossref","first-page":"e1000584","DOI":"10.1371\/journal.pgen.1000584","volume":"5","author":"G Jun","year":"2009","unstructured":"Jun G, Guo H, Klein BE, Klein R, Wang JJ, Mitchell P et al (2009) EPHA2 is associated with age-related cortical cataract in mice and humans. PLoS Genet 5:e1000584","journal-title":"PLoS Genet"},{"key":"9470_CR11","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1590\/S0004-27492011000200008","volume":"74","author":"FP Magalh\u00e3es","year":"2011","unstructured":"Magalh\u00e3es FP, Costa EF, Cariello AJ, Rodrigues EB, Hofling-Lima AL (2011) Comparative analysis of the nuclear lens opalescence by the Lens Opacities Classification System III with nuclear density values provided by Oculus Pentacam: a cross-section study using Pentacam Nucleus Staging software. Arq Bras Oftalmol 74:110\u2013113","journal-title":"Arq Bras Oftalmol"},{"key":"9470_CR12","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1098\/rstb.2010.0300","volume":"366","author":"R Michael","year":"2011","unstructured":"Michael R, Bron AJ (2011) The ageing lens and cataract: a model of normal and pathological aging. Philos Trans R Soc Lond B Biol Sci 366:1278\u20131292","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"9470_CR13","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1086\/319512","volume":"68","author":"Y Okano","year":"2001","unstructured":"Okano Y, Asada M, Fujimoto A, Ohtake A, Murayama K, Hsiao KJ et al (2001) A genetic factor for age-related cataract: identification and characterization of a novel galactokinase variant, \u201cOsaka\u201d, in Asians. Am J Hum Genet 68:1036\u20131042","journal-title":"Am J Hum Genet"},{"key":"9470_CR14","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.exer.2008.08.013","volume":"87","author":"S Pal-Gosh","year":"2008","unstructured":"Pal-Gosh S, Tadvalkar G, Jurjus RA, Zieske JD, Stepp MA (2008) BALB\/c and C57BL6 mouse strains vary in their ability to heal corneal epithelial debridement wounds. Exp Eye Res 87:478\u2013486","journal-title":"Exp Eye Res"},{"key":"9470_CR15","doi-asserted-by":"crossref","first-page":"4661","DOI":"10.1167\/iovs.05-0808","volume":"46","author":"W Pendergrass","year":"2005","unstructured":"Pendergrass W, Penn P, Possin D, Wolf N (2005) Accumulation of DNA, nuclear and mitochondrial debris, and ROS at sites of age-related cortical cataract in mice. Invest Ophthalmol Vis Sci 46:4661\u20134670","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"9470_CR16","first-page":"2672","volume":"17","author":"W Pendergrass","year":"2011","unstructured":"Pendergrass W, Zitnik G, Urfer SR, Wolf N (2011) Age-related retention of fiber cell nuclei and nuclear fragments in the lens of multiple species. Mol Vis 17:2672\u20132684","journal-title":"Mol Vis"},{"key":"9470_CR17","doi-asserted-by":"crossref","first-page":"5653","DOI":"10.1167\/iovs.09-3550","volume":"50","author":"O Puk","year":"2009","unstructured":"Puk O, Dalke C, Calzada-Wack J, Ahmad N, Klaften M et al (2009) Reduced corneal thickness and enlarged anterior chamber depth in a novel ColIIIa2G257D mutant mouse. Invest Ophthalmol Vis Sci 50:5653\u20135661","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"9470_CR18","first-page":"1164","volume":"17","author":"O Puk","year":"2011","unstructured":"Puk O, Ahmad N, Wagner S, Hrab\u00e9 de Angelis M, Graw J (2011a) Microphakia and congenital cataract formation in a novel Lim2(C51R) mutant mouse. Mol Vis 17:1164\u20131171","journal-title":"Mol Vis"},{"key":"9470_CR19","doi-asserted-by":"crossref","first-page":"e23678","DOI":"10.1371\/journal.pone.0023678","volume":"6","author":"O Puk","year":"2011","unstructured":"Puk O, M\u00f6ller G, Geerlof A, Krowiorz K, Ahmad N, Wagner S, Adamski J, Hrab\u00e9 de Angelis M, Graw J (2011b) The pathologic effect of a novel neomorphic Fgf9(Y162C) allele is restricted to decreased vision and retarded lens growth. PLoS One 6:e23678. doi: 10.1371\/journal.pone.0023678","journal-title":"PLoS One"},{"key":"9470_CR20","doi-asserted-by":"crossref","first-page":"501","DOI":"10.2353\/ajpath.2010.090794","volume":"177","author":"B Regenfuss","year":"2010","unstructured":"Regenfuss B, Onderka J, Bock F, Hos D, Maruyama K, Cursiefen C (2010) Genetic heterogeneity of lymphangiogenesis in different mouse strains. Am J Pathol 177:501\u2013510","journal-title":"Am J Pathol"},{"key":"9470_CR21","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/j.exer.2003.09.028","volume":"78","author":"A Sandilands","year":"2004","unstructured":"Sandilands A, Wang X, Hutcheson AM, James J, Prescott AR, Wegener A, Pekny M, Gong X, Quinlan RA (2004) Bsfp2 mutation found in 129 strains causes the loss of CP49\u2019 and induces vimentin-dependent changes in the lens fibre cell cytoskeleton. Exp Eye Res 78:875\u2013889","journal-title":"Exp Eye Res"},{"key":"9470_CR22","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1590\/S0004-27492011000200016","volume":"74","author":"A Santana","year":"2011","unstructured":"Santana A, Waiswo M (2011) The genetic and molecular basis of congenital cataract. Arq Bras Oftalmol 74:136\u2013142","journal-title":"Arq Bras Oftalmol"},{"key":"9470_CR23","first-page":"1850","volume":"14","author":"Y Shi","year":"2008","unstructured":"Shi Y, Shi X, Jin Y, Miao A, Bu L, He J, Jiang H, Lu Y, Kong X, Hu L (2008) Mutation screening of HSF4 in 150 age-related cataract patients. Mol Vis 14:1850\u20131855","journal-title":"Mol Vis"},{"key":"9470_CR24","doi-asserted-by":"crossref","first-page":"4931","DOI":"10.1167\/iovs.06-0423","volume":"47","author":"VN Simirskii","year":"2006","unstructured":"Simirskii VN, Lee RS, Wawrousek EF, Duncan MK (2006) Inbred FVB\/N mice are mutant at the cp49\/Bsfp2 locus and lack beaded filament proteins in the lens. Invest Ophthalmol Vis Sci 47:4931\u20134934","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"9470_CR25","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1093\/hmg\/11.7.755","volume":"11","author":"C Thaung","year":"2002","unstructured":"Thaung C, West K, Clark BJ, McKie L, Morgan JE et al (2002) Novel ENU-induced mutations in the mouse: models for human eye disease. Hum Mol Genet 11:755\u2013767","journal-title":"Hum Mol Genet"},{"key":"9470_CR26","first-page":"205","volume":"43","author":"Y Ueda","year":"2002","unstructured":"Ueda Y, Duncan MK, David LL (2002) Lens proteomics: the accumulation of crystallin modifications in the mouse lens with age. Invest Ophthalmol Vis Sci 43:205\u2013215","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"9470_CR27","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1093\/oxfordjournals.epirev.a018025","volume":"22","author":"SK West","year":"2000","unstructured":"West SK (2000) Looking forward to 20\/20: a focus on the epidemiology of eye diseases. Epidemiol Rev 22:64\u201370","journal-title":"Epidemiol Rev"},{"key":"9470_CR28","first-page":"274","volume":"14","author":"N Wolf","year":"2008","unstructured":"Wolf N, Pendergrass W, Singh N, Swisshelm K, Schwartz J (2008) Radiation cataracts: mechanisms involved in their long delayed occurrence but then rapid progression. Mol Vis 14:274\u2013285","journal-title":"Mol Vis"},{"key":"9470_CR29","first-page":"2325","volume":"17","author":"Y Zhang","year":"2011","unstructured":"Zhang Y, Zhang L, Sun D, Li Z, Wang L, Liu P (2011) Genetic polymorphisms of superoxide dismutases, catalase, and glutathione peroxidase in age-related cataract. Mol Vis 17:2325\u20132332","journal-title":"Mol Vis"},{"key":"9470_CR30","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1016\/j.ophtha.2011.11.004","volume":"119","author":"Y Zhang","year":"2012","unstructured":"Zhang Y, Zhang L, Song Z, Sun DL, Liu HR, Fu SB, Liu DR, Liu P (2012) Genetic polymorphisms in DNA repair genes OGG1, APE1, XRCC1, and XPD and the risk of age-related cataract. Ophthalmology 119:900\u2013906","journal-title":"Ophthalmology"},{"key":"9470_CR31","first-page":"621","volume":"17","author":"Z Zhou","year":"2011","unstructured":"Zhou Z, Wang B, Hu S, Zhang C, Ma X, Qi Y (2011) Genetic variations in GJA3, GJA8, LIM2, and age-related cataract in the Chinese population: a mutation screening study. Mol Vis 17:621\u2013626","journal-title":"Mol Vis"}],"container-title":["Mammalian Genome"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00335-013-9470-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00335-013-9470-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00335-013-9470-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T08:21:00Z","timestamp":1559031660000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00335-013-9470-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8]]},"references-count":31,"journal-issue":{"issue":"7-8","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["9470"],"URL":"https:\/\/doi.org\/10.1007\/s00335-013-9470-2","relation":{},"ISSN":["0938-8990","1432-1777"],"issn-type":[{"value":"0938-8990","type":"print"},{"value":"1432-1777","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8]]}}}