{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T18:06:43Z","timestamp":1791137203776,"version":"4.1.0"},"reference-count":85,"publisher":"Springer Science and Business Media LLC","issue":"1-2","license":[{"start":{"date-parts":[[2017,12,2]],"date-time":"2017-12-02T00:00:00Z","timestamp":1512172800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2017,12,2]],"date-time":"2017-12-02T00:00:00Z","timestamp":1512172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["R15ES020053"],"award-info":[{"award-number":["R15ES020053"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["ES05605"],"award-info":[{"award-number":["ES05605"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["ES013661"],"award-info":[{"award-number":["ES013661"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["P20GM103436"],"award-info":[{"award-number":["P20GM103436"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["RSF-034-07"],"award-info":[{"award-number":["RSF-034-07"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["DUE-STEP-096928"],"award-info":[{"award-number":["DUE-STEP-096928"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009814","name":"Northern Kentucky University Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009814","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011939","name":"Center for Integrative Natural Science and Mathematics, Northern Kentucky University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011939","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Northern Kentucky University Dorothy Westerman Herrmann Fund"},{"DOI":"10.13039\/100009813","name":"Northern Kentucky University","doi-asserted-by":"publisher","award":["College of Arts & Sciences"],"award-info":[{"award-number":["College of Arts & Sciences"]}],"id":[{"id":"10.13039\/100009813","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mamm Genome"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1007\/s00335-017-9728-1","type":"journal-article","created":{"date-parts":[[2017,12,2]],"date-time":"2017-12-02T02:06:42Z","timestamp":1512180402000},"page":"112-127","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Genetic differences in the aryl hydrocarbon receptor and CYP1A2 affect sensitivity to developmental polychlorinated biphenyl exposure in mice: relevance to studies of human neurological disorders"],"prefix":"10.1007","volume":"29","author":[{"given":"Kelsey","family":"Klinefelter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Molly Kromme","family":"Hooven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chloe","family":"Bates","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Breann T.","family":"Colter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Dailey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smitha Krishnan","family":"Infante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Izabela","family":"Kania-Korwel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-Joachim","family":"Lehmler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"L\u00f3pez-Ju\u00e1rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clare Pickering","family":"Ludwig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6693-0452","authenticated-orcid":false,"given":"Christine Perdan","family":"Curran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,12,2]]},"reference":[{"key":"9728_CR1","unstructured":"Agency for Toxic Substances and Disease Registry (ATSDR) (2015). 2015 CERCLA National priorities list of hazardous substances. U.S. Department of Health and Human Services, Public Health Service. Atlanta. https:\/\/www.atsdr.cdc.gov\/spl\/"},{"issue":"8","key":"9728_CR2","doi-asserted-by":"publisher","first-page":"4001","DOI":"10.1210\/en.2007-1774","volume":"149","author":"R Bansal","year":"2008","unstructured":"Bansal R, Zoeller RT (2008) Polychlorinated biphenyls (Aroclor 1254) do not uniformly produce agonist actions on thyroid hormone responses in the developing rat brain. Endocrinology 149(8):4001\u20134008","journal-title":"Endocrinology"},{"key":"9728_CR3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.envint.2017.07.008","volume":"108","author":"K B\u00e1nyiov\u00e1","year":"2017","unstructured":"B\u00e1nyiov\u00e1 K, \u010cern\u00e1 M, Mike\u0161 O, Komprdov\u00e1 K, Sharma A, Gyalpo T, \u010cupr P, Scheringer M (2017) Long-term time trends in human intake of POPs in the Czech Republic indicate a need for continuous monitoring. Environ Int 108:1\u201310","journal-title":"Environ Int"},{"key":"9728_CR4","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1016\/j.neuro.2013.07.003","volume":"38","author":"SA Berghuis","year":"2013","unstructured":"Berghuis SA, Soechitram SD, Hitzert MM, Sauer PJJ, Bos AF (2013) Prenatal exposure to polychlorinated biphenyls and their hydroxylated metabolites is associated with motor development of three-month-old infants. NeuroToxicol 38:124\u2013130","journal-title":"NeuroToxicol"},{"key":"9728_CR5","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/j.envint.2016.08.010","volume":"95","author":"O Boucher","year":"2016","unstructured":"Boucher O, Muckle G, Ayotte P, Dewailly E, Jacobson SW, Jacobson JL. (2016). Altered fine motor function at school age in Inuit children exposed to PCBs, methylmercury, and lead. Environ Int 95:144\u2013151","journal-title":"Environ Int"},{"issue":"1","key":"9728_CR6","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1289\/ehp.11702","volume":"117","author":"J Bronstein","year":"2009","unstructured":"Bronstein J, Carvey P, Chen H, Cory-Slechta D, DiMonte D, Duda J, English P, Goldman S, Grate S, Hansen J, Hoppin J, Jewell S, Kamel F, Koroshetz W, Langston JW, Logroscino G, Nelson L, Ravina B, Rocca W, Ross GW, Schettler T, Schwarzschild M, Scott B, Seegal R, Singleton A, Steenland K, Tanner CM, Van Den Eeden S, Weisskopf M (2009) Meeting report: consensus statement-Parkinson\u2019s disease and the environment: collaborative on health and the environment and Parkinson\u2019s Action Network (CHE PAN) conference 26\u201328 June 2007. Environ Health Perspect 117(1):117\u2013121","journal-title":"Environ Health Perspect"},{"key":"9728_CR7","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1093\/toxsci\/kfl018","volume":"92","author":"WM Caudle","year":"2006","unstructured":"Caudle WM, Richardson JR, Delea KC, Guillot TS, Wang M, Pennell KD, Miller GW (2006) Polychlorinated biphenyl-induced reduction of dopamine transporter expression as a precursor to Parkinson\u2019s disease-associated dopamine toxicity. Toxicol Sci 92:490\u2013499","journal-title":"Toxicol Sci"},{"key":"9728_CR8","doi-asserted-by":"crossref","unstructured":"Colter BT, Garber HF, Fleming SM, Fowler JP, Harding GD, Hooven MK, Howes AA, Infante SK, Lang AL, MacDougall MC, Stegman M, Taylor K, Curran CP (2017) Ahr and Cyp1a2 genotypes both affect susceptibility to motor deficits following gestational and lactational exposure to polychlorinated biphenyls. NeuroToxicology (submitted)","DOI":"10.1101\/184010"},{"issue":"1","key":"9728_CR9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.fct.2005.01.005","volume":"44","author":"I Costabeber","year":"2006","unstructured":"Costabeber I, Dos Santos JS, Xavier AA, Weber J, Le\u00e3es FL, Junior SB, Emanuelli T (2006) Levels of polychlorinated biphenyls (PCBs) in meat and meat products from the state of Rio Grande do Sul, Brazil. Food Chem Toxicol 44(1):1\u20137","journal-title":"Food Chem Toxicol"},{"key":"9728_CR10","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1093\/toxsci\/kfj048","volume":"89","author":"CP Curran","year":"2006","unstructured":"Curran CP, Miller KA, Dalton TP, Vorhees CV, Miller ML, Shertzer HG et al (2006) Genetic differences in lethality of newborn mice treated in utero with coplanar versus non-coplanar hexabromobiphenyl. Toxicol Sci 89:454\u2013464","journal-title":"Toxicol Sci"},{"key":"9728_CR11","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1093\/toxsci\/kfq314","volume":"119","author":"CP Curran","year":"2011","unstructured":"Curran CP, Vorhees CV, Williams MT, Genter MB, Nebert DW (2011a) In utero and lactational exposure to a complex mixture of polychlorinated biphenyls: toxicity in pups dependent on the Cyp1a2. and Ahr genotypes. Toxicol Sci 119:189\u2013208","journal-title":"Toxicol Sci"},{"issue":"9","key":"9728_CR12","doi-asserted-by":"publisher","first-page":"1286","DOI":"10.1289\/ehp.1002965","volume":"119","author":"CP Curran","year":"2011","unstructured":"Curran CP, Nebert DW, Genter MB, Patel KV, Schafer TL, Skelton MR, Williams MT, Vorhees CV (2011b) In utero and lactational exposure to PCBs in mice: adult offspring show altered learning and memory depending on Cyp1a2 and Ahr genotypes. Enironv Health Perspect 119(9):1286\u20131293","journal-title":"Enironv Health Perspect"},{"issue":"6","key":"9728_CR13","doi-asserted-by":"publisher","first-page":"1436","DOI":"10.1016\/j.neuro.2012.08.005","volume":"33","author":"CP Curran","year":"2012","unstructured":"Curran CP, Altenhofen E, .Ashworth AA, .Brown A, Curran MA, Evans A, Floyd R, Fowler JP, Garber H, Hays B, Kamau-Cheggeh C, Kraemer S, Lang AL, Mynhier A, Samuels A, Strohamier C (2012) Ahr d Cyp1a2(\u2212\/\u2212) mice show increased susceptibility to PCB-induced developmental neurotoxicity. Neurotoxicology 33(6):1436\u20131442","journal-title":"Neurotoxicology"},{"issue":"1","key":"9728_CR14","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1007\/s12311-008-0004-5","volume":"7","author":"VM Darras","year":"2008","unstructured":"Darras VM (2008) Endocrine disrupting polyhalogenated organic pollutants interfere with thyroid hormone signalling in the developing brain. Cerebellum 7(1):26\u201337","journal-title":"Cerebellum"},{"key":"9728_CR100","doi-asserted-by":"crossref","unstructured":"Denison MS, Faber SC (2017) And now for something completely different: diversity in ligand-dependent activation of Ah receptor responses. Curr Opin Toxicol 2:124\u2013131","DOI":"10.1016\/j.cotox.2017.01.006"},{"key":"9728_CR15","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1006\/bbrc.1997.6973","volume":"236","author":"JJ Diliberto","year":"1997","unstructured":"Diliberto JJ, Burgin D, Birnbaum LS (1997) Role of CYP1A2 in hepatic sequestration of dioxin: studies using CYP1A2 knock-out mice. Biochem Biophys Res Commun 236:431\u2013433","journal-title":"Biochem Biophys Res Commun"},{"key":"9728_CR17","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.1080\/10807030390240274","volume":"9","author":"J Doull","year":"2003","unstructured":"Doull J (2003) The \u201cRed Book\u201d and other risk assessment milestones. Hum Ecol Risk Assess 9:1229\u20131238","journal-title":"Hum Ecol Risk Assess"},{"key":"9728_CR18","doi-asserted-by":"publisher","first-page":"18591","DOI":"10.1074\/jbc.M601159200","volume":"281","author":"N Dragin","year":"2006","unstructured":"Dragin N, Dalton TP, Miller ML, Shertzer HG, Nebert DW (2006) For dioxin-induced birth defects, mouse or human CYP1A2 in maternal liver protects whereas mouse CYP1A1 and CYP1B1 are inconsequential. J Biol Chem 281:18591\u201318600","journal-title":"J Biol Chem"},{"key":"9728_CR19","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1242\/dev.103226","volume":"141","author":"T Fauquier","year":"2014","unstructured":"Fauquier T, Chatonnet F, Picou F, Richard S, Fossat N, Aguilera N, Lamonerie T, Flamant F (2014) Purkinje cells and Bergmann glia are primary targets of the TR\u03b11 thyroid hormone receptor during mouse cerebellum postnatal development. Development 141:166\u2013175","journal-title":"Development"},{"key":"9728_CR20","doi-asserted-by":"publisher","first-page":"1623","DOI":"10.1289\/ehp.10328","volume":"115","author":"KJ Gauger","year":"2007","unstructured":"Gauger KJ, Giera S, Sharlin DS, Bansal R, Iannacone E, Zoeller RT (2007) Polychlorinated biphenyls 105 and 118 form thyroid hormone receptor agonists after cytochrome P4501A1 activation in rat pituitary GH3 cells. Environ Health Perspect 115:1623\u20131630","journal-title":"Environ Health Perspect"},{"issue":"7","key":"9728_CR21","doi-asserted-by":"publisher","first-page":"2909","DOI":"10.1210\/en.2010-1490","volume":"152","author":"S Giera","year":"2011","unstructured":"Giera S, Bansal R, Ortiz-Toro TM, Taub DG, Zoeller RT (2011) Individual polychlorinated biphenyl (PCB) congeners produce tissue- and gene-specific effects on thyroid hormone signaling during development. Endocrinology 152(7):2909\u20132919","journal-title":"Endocrinology"},{"issue":"1","key":"9728_CR22","first-page":"94","volume":"45","author":"ES Goldey","year":"1998","unstructured":"Goldey ES, Crofton KM (1998) Thyroxine replacement attenuates hypothyroxinemia, hearing loss, and motor deficits following developmental exposure to Aroclor 1254 in rats. Toxicol Sci 45(1):94\u2013105","journal-title":"Toxicol Sci"},{"key":"9728_CR23","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1146\/annurev-pharmtox-011613-135937","volume":"54","author":"SM Goldman","year":"2014","unstructured":"Goldman SM (2014) Environmental toxins and Parkinson\u2019s disease. Annu Rev Pharmacol Toxicol 54:141\u2013164","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"9728_CR24","doi-asserted-by":"publisher","first-page":"8406","DOI":"10.1021\/jf050835z","volume":"53","author":"B Gomara","year":"2005","unstructured":"Gomara B, Bordajandi LR, Fernandez MA, Herrero L, Abad E, Abalos M, Rivera J, Gonz\u00e1lez MJ (2005) Levels and trends of polychlorinated dibenzo-p-dioxins\/furans (PCDD\/Fs) and dioxin-like polychlorinated biphenyls (PCBs) in Spanish commercial fish and shellfish products, 1995\u20132003. J Agric Food Chem 53:8406\u20138413","journal-title":"J Agric Food Chem"},{"key":"9728_CR25","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.nlm.2017.02.001","volume":"40","author":"DA Gonz\u00e1lez-Franco","year":"2017","unstructured":"Gonz\u00e1lez-Franco DA, Ram\u00edrez-Amaya V, Joseph-Bravo P, Prado-Alcal\u00e1 RA, Quirarte GL (2017) Differential Arc protein expression in dorsal and ventral striatum after moderate and intense inhibitory avoidance training. Neurobiol Learn Mem 40:17\u201326","journal-title":"Neurobiol Learn Mem"},{"issue":"4","key":"9728_CR26","doi-asserted-by":"publisher","first-page":"407","DOI":"10.2131\/jts.42.407","volume":"42","author":"A Haijima","year":"2017","unstructured":"Haijima A, Lesmana R, Shimokawa N, Amano I, Takatsuru Y, Koibuchi N (2017) Differential neurotoxic effects of in utero and lactational exposure to hydroxylated polychlorinated biphenyl (OH-PCB 106) on spontaneous locomotor activity and motor coordination in young adult male mice. J Toxicol Sci 42(4):407\u2013416","journal-title":"J Toxicol Sci"},{"key":"9728_CR27","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1038\/379736a0","volume":"379","author":"BA Hamilton","year":"1996","unstructured":"Hamilton BA, Frankel WN, Kerrebrock AW, Hawkins TL, FitzHugh W, Kusumi K, Russell LB, Mueller KL, van Berkel V, Birren BW, Kruglyak L, Lander ES (1996) Disruption of the nuclear hormone receptor ROR\u03b1 in staggerer mice. Nature 379:736\u2013739","journal-title":"Nature"},{"key":"9728_CR101","doi-asserted-by":"crossref","unstructured":"Hatcher-Martin JM, Gearing M, Steenland K, Levey AI, Miller GW, Pennell KD (2012) Association between polychlorinated biphenyls and Parkinson\u2019s disease neuropathology. Neurotoxicology 33:1298\u20131304","DOI":"10.1016\/j.neuro.2012.08.002"},{"key":"9728_CR28","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1186\/1476-069X-10-56","volume":"10","author":"RF Herrick","year":"2011","unstructured":"Herrick RF, Meeker JD, Altshul L (2011) Serum PCB levels and congener profiles among teachers in PCB-containing schools: a pilot study. Environ Health 10:56","journal-title":"Environ Health"},{"issue":"12","key":"9728_CR29","doi-asserted-by":"publisher","first-page":"3696","DOI":"10.1021\/es0525657","volume":"40","author":"L Hovander","year":"2006","unstructured":"Hovander L, Linderholm L, Athanasiadou M, Athanassiadis I, Bignert A, F\u00e4ngstr\u00f6m B, Kocan A, Petrik J, Trnovec T, Bergman A (2006) Levels of PCBs and their metabolites in the serum of residents of a highly contaminated area in eastern Slovakia. Environ Sci Technol 40(12):3696\u20133703","journal-title":"Environ Sci Technol"},{"issue":"8","key":"9728_CR30","doi-asserted-by":"publisher","first-page":"2822","DOI":"10.1021\/es902413k","volume":"44","author":"D Hu","year":"2010","unstructured":"Hu D, Hornbuckle KC (2010) Inadvertent polychlorinated biphenyls in commercial paint pigments. Environ Sci Technol 44(8):2822\u20132827","journal-title":"Environ Sci Technol"},{"key":"9728_CR31","first-page":"415","volume":"18","author":"JL Jacobson","year":"1997","unstructured":"Jacobson JL, Jacobson SW (1997) Evidence for PCBs as neurodevelopmental toxicants in humans. Neurotoxicology 18:415\u2013424","journal-title":"Neurotoxicology"},{"key":"9728_CR32","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1067\/S0022-3476(03)00577-8","volume":"143","author":"JL Jacobson","year":"2003","unstructured":"Jacobson JL, Jacobson SW (2003) Prenatal exposure to polychlorinated biphenyls and attention at school age. J Pediatr 143:780\u2013788","journal-title":"J Pediatr"},{"key":"9728_CR33","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1016\/j.chemosphere.2004.04.035","volume":"56","author":"I Kania-Korwel","year":"2004","unstructured":"Kania-Korwel I, Parkin S, Robertson LW, Lehmler H-J (2004) Synthesis of polychlorinated biphenyls and their metabolites with a modified Suzuki-coupling. Chemosphere 56:735\u2013744","journal-title":"Chemosphere"},{"key":"9728_CR34","doi-asserted-by":"publisher","first-page":"3513","DOI":"10.1021\/es047987f","volume":"39","author":"I Kania-Korwel","year":"2005","unstructured":"Kania-Korwel I, Hornbuckle KC, Peck A, Ludewig G, Robertson LW, Sulkowski WW, Espandiari P, Gairola CG, Lehmler H-J (2005) Congener specific tissue distribution of Aroclor 1254 and a highly chlorinated environmental PCB mixture in rats. Environ Sci Technol 39:3513\u20133520","journal-title":"Environ Sci Technol"},{"key":"9728_CR35","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1002\/chir.20342","volume":"19","author":"I Kania-Korwel","year":"2007","unstructured":"Kania-Korwel I, Shaikh N, Hornbuckle KC, Robertson LW, Lehmler H-J (2007) Enantioselective disposition of PCB 136 (2,2\u2032,3,3\u2032,6,6\u2032-hexachlorobiphenyl) in C57BL\/6 mice after oral and intraperitoneal administration. Chirality 19:56\u201366","journal-title":"Chirality"},{"key":"9728_CR36","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.chroma.2008.10.089","volume":"1214","author":"I Kania-Korwel","year":"2008","unstructured":"Kania-Korwel I, Zhao H, Norstrom K, Li X, Hornbuckle KC, Lehmler HJ (2008) Simultaneous extraction and clean-up of polychlorinated biphenyls and their metabolites from small tissue samples using pressurized liquid extraction. J Chromatogr A 1214:37\u201346","journal-title":"J Chromatogr A"},{"key":"9728_CR38","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1016\/j.chemosphere.2015.12.113","volume":"147","author":"WX Koh","year":"2016","unstructured":"Koh WX, Hornbuckle KC, Marek RF, Wang K, Thorne PS (2016) Hydroxylated polychlorinated biphenyls in human sera from adolescents and their mothers living in two U.S. Midwestern communities. Chemosphere 147:389\u2013395","journal-title":"Chemosphere"},{"issue":"4","key":"9728_CR39","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/S1043-2760(00)00238-1","volume":"11","author":"N Koibuchi","year":"2000","unstructured":"Koibuchi N, Chin WW (2000) Thyroid hormone action and brain development. Trends Endocrinol Metab 11(4):123\u2013128","journal-title":"Trends Endocrinol Metab"},{"issue":"3","key":"9728_CR40","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1089\/105072501750159534","volume":"11","author":"N Koibuchi","year":"2001","unstructured":"Koibuchi N, Yamaoka S, Chin WW (2001) Effect of altered thyroid status on neurotrophin gene expression during postnatal development of the mouse cerebellum. Thyroid 11(3):205\u2013210","journal-title":"Thyroid"},{"issue":"19","key":"9728_CR41","doi-asserted-by":"publisher","first-page":"6176","DOI":"10.1021\/es0608646","volume":"40","author":"GH Lambert","year":"2006","unstructured":"Lambert GH, Needham LL, Turner W, Lai TJ, Patterson DG Jr, Guo YL (2006) Induced CYP1A2 activity as a phenotypic biomarker in humans highly exposed to certain PCBs\/PCDFs. Environ Sci Technol 40(19):6176\u20136180","journal-title":"Environ Sci Technol"},{"key":"9728_CR42","doi-asserted-by":"publisher","first-page":"S379","DOI":"10.1016\/j.chemosphere.2006.05.132","volume":"67","author":"P Langer","year":"2007","unstructured":"Langer P, Kocan A, Tajtakova M, Petrik J, Chovancova J, Drobna B et al (2007) Fish from industrially polluted freshwater as the main source of organochlorinated pollutants and increased frequency of thyroid disorders and dysglycemia. Chemosphere 67:S379\u2013S385","journal-title":"Chemosphere"},{"issue":"2","key":"9728_CR43","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1093\/toxsci\/kfr313","volume":"125","author":"DW Lee","year":"2012","unstructured":"Lee DW, Notter SA, Thiruchelvam M, Dever DP, Fitzpatrick R, Kostyniak PJ, Cory-Slechta DA, Opanashuk LA (2012) Subchronic polychlorinated biphenyl (Aroclor 1254) exposure produces oxidative damage and neuronal death of ventral midbrain dopaminergic systems. Toxicol Sci 125(2):496\u2013508","journal-title":"Toxicol Sci"},{"key":"9728_CR44","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/S0045-6535(00)00546-4","volume":"45","author":"H-J Lehmler","year":"2001","unstructured":"Lehmler H-J, Robertson LW (2001) Synthesis of polychlorinated biphenyls (PCBs) using the Suzuki-coupling. Chemosphere 45:137\u2013143","journal-title":"Chemosphere"},{"issue":"4","key":"9728_CR45","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1289\/ehp.9773","volume":"115","author":"PJ Lein","year":"2007","unstructured":"Lein PJ, Yang D, Bachstetter AD, Tilson HA, Harry GJ, Mervis RF, Kodavanti PR (2007) Ontogenetic alterations in molecular and structural correlates of dendritic growth after developmental exposure to polychlorinated biphenyls. Environ Health Perspect 115(4):556\u2013563","journal-title":"Environ Health Perspect"},{"issue":"4","key":"9728_CR46","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1080\/152873901316981312","volume":"64","author":"TM Lin","year":"2001","unstructured":"Lin TM, Ko K, Moore RW, Buchanan DL, Cooke PS, Peterson RE (2001) Role of the aryl hydrocarbon receptor in the development of control and 2,3,7,8-tetrachlorodibenzo-p-dioxin-exposed male mice. J Toxicol Environ Health A 64(4):327\u2013342","journal-title":"J Toxicol Environ Health A"},{"issue":"1","key":"9728_CR47","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1093\/toxsci\/71.1.20","volume":"71","author":"P Lin","year":"2003","unstructured":"Lin P, Hu SW, Chang TH (2003) Correlation between gene expression of aryl hydrocarbon receptor (AhR), hydrocarbon receptor nuclear translocator (Arnt), cytochromes P4501A1 (CYP1A1) and 1B1 (CYP1B1), and inducibility of CYP1A1 and CYP1B1 in human lymphocytes. Toxicol Sci 71(1):20\u201326","journal-title":"Toxicol Sci"},{"issue":"4","key":"9728_CR49","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1002\/glia.21126","volume":"59","author":"A L\u00f3pez-Ju\u00e1rez","year":"2011","unstructured":"L\u00f3pez-Ju\u00e1rez A, Morales-L\u00e1zaro S, S\u00e1nchez-S\u00e1nchez R, Sunkara M, Lomel\u00ed H, Velasco I, Morris AJ, Escalante-Alcalde D (2011) Expression of LPP3 in Bergmann glia is required for proper cerebellar sphingosine-1-phosphate metabolism\/signaling and development. Glia 59(4):577\u2013589","journal-title":"Glia"},{"key":"9728_CR50","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1289\/ehp.6409","volume":"112","author":"J Maervoet","year":"2004","unstructured":"Maervoet J, Covaci A, Schepens P, Sandau CD, Letcher R (2004) A reassessment of the nomenclature of polychlorinated biphenyl (PCB) metabolites. Environ Health Perspect 112:291\u2013294","journal-title":"Environ Health Perspect"},{"issue":"22","key":"9728_CR51","doi-asserted-by":"publisher","first-page":"13459","DOI":"10.1021\/es502490w","volume":"48","author":"RF Marek","year":"2014","unstructured":"Marek RF, Thorne PS, DeWall J, Hornbuckle KC (2014) Variability in PCB and OH-PCB serum levels in children and their mothers in urban and rural U.S. communities. Environ Sci Technol 48(22):13459\u201313467","journal-title":"Environ Sci Technol"},{"issue":"14","key":"9728_CR52","doi-asserted-by":"publisher","first-page":"7853","DOI":"10.1021\/acs.est.7b01910","volume":"51","author":"RF Marek","year":"2017","unstructured":"Marek RF, Thorne PS, Herkert NJ, Awad AM, Hornbuckle KC (2017) Airborne PCBs and OH-PCBs inside and outside urban and rural U.S. schools. Environ Sci Technol 51(14):7853\u20137860","journal-title":"Environ Sci Technol"},{"key":"9728_CR53","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1016\/j.plipres.2017.06.001","volume":"67","author":"DW Nebert","year":"2017","unstructured":"Nebert DW (2017) Aryl hydrocarbon receptor (AHR): \u201cpioneer member\u201d of the basic-helix\/loop\/helix per-Arnt-sim (bHLH\/PAS) family of \u201csensors\u201d of foreign and endogenous signals. Prog Lipid Res 67:38\u201357","journal-title":"Prog Lipid Res"},{"key":"9728_CR54","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1038\/nrc2015","volume":"6","author":"DW Nebert","year":"2006","unstructured":"Nebert DW, Dalton TP (2006) The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis. Nat Rev Cancer 6:947\u2013960","journal-title":"Nat Rev Cancer"},{"issue":"1612","key":"9728_CR55","doi-asserted-by":"publisher","first-page":"20120431","DOI":"10.1098\/rstb.2012.0431","volume":"368","author":"DW Nebert","year":"2013","unstructured":"Nebert DW, Wikvall K, Miller WL (2013) Human cytochromes P450 in health and disease. Philos Trans R Soc Lond B Biol Sci 368(1612):20120431","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"9728_CR56","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1016\/j.pharmthera.2009.10.009","volume":"125","author":"IN Pessah","year":"2010","unstructured":"Pessah IN, Cherednichenko G, Lein PJ (2010) Minding the calcium store: Ryanodine receptor activation as a convergent mechanism of PCB toxicity. Pharmacol Ther 125:260\u2013285","journal-title":"Pharmacol Ther"},{"key":"9728_CR57","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1016\/j.neuro.2008.03.001","volume":"29","author":"MS Petersen","year":"2008","unstructured":"Petersen MS, Halling J, Bech S, Wermuth L, Weihe P, Nielsen F et al (2008) Impact of dietary exposure to food contaminants on the risk of Parkinson\u2019s disease. Neurotoxicology 29:584\u2013590","journal-title":"Neurotoxicology"},{"issue":"8","key":"9728_CR58","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1089\/thy.2008.0336","volume":"19","author":"CH Qiu","year":"2009","unstructured":"Qiu CH, Miyazaki W, Iwasaki T, Londo\u00f1o M, Ibhazehiebo K, Shimokawa N, Koibuchi N (2009) Retinoic Acid receptor-related orphan receptor alpha-enhanced thyroid hormone receptor-mediated transcription requires its ligand binding domain which is not, by itself, sufficient: possible direct interaction of two receptors. Thyroid 19(8):893\u2013898","journal-title":"Thyroid"},{"key":"9728_CR59","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1289\/ehp.1002415","volume":"119","author":"CL Quinn","year":"2011","unstructured":"Quinn CL, Wania F, Czub G, Breivik K (2011) Investigating intergenerational differences in human PCB exposure due to variable emissions and reproductive behaviors. Environ Health Perspect 119:641\u2013646","journal-title":"Environ Health Perspect"},{"key":"9728_CR60","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/j.ecoenv.2004.06.003","volume":"59","author":"G Ross","year":"2004","unstructured":"Ross G (2004) The public health implications of polychlorinated biphenyls (PCBs) in the environment. Ecotoxicol Environ Saf 59:275\u2013291","journal-title":"Ecotoxicol Environ Saf"},{"issue":"2\u20133","key":"9728_CR61","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1016\/j.ijheh.2013.04.006","volume":"217","author":"AM Ruder","year":"2014","unstructured":"Ruder AM, Hein MJ, Hopf NB, Waters MA. (2014). Mortality among 24,865 workers exposed to polychlorinated biphenyls (PCBs) in three electrical capacitor manufacturing plants: a ten-year update. Int J Hyg Environ Health 217(2\u20133):176\u2013187","journal-title":"Int J Hyg Environ Health"},{"key":"9728_CR62","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1289\/ehp.00108611","volume":"108","author":"CD Sandau","year":"2000","unstructured":"Sandau CD, Ayotte P, Dewailly E, Duffe J, Norstrom RJ (2000) Analysis of hydroxylated metabolites of PCBs (OH-PCBs) and other chlorinated phenolic compounds in whole blood from Canadian inuit. Environ Health Perspect 108:611\u2013616","journal-title":"Environ Health Perspect"},{"key":"9728_CR63","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1289\/ehp.5461","volume":"111","author":"SL Schantz","year":"2003","unstructured":"Schantz SL, Widholm JJ, Rice DC (2003) Effects of PCB exposure on neuropsychological function in children. Environ Health Perspect 111:357\u2013576","journal-title":"Environ Health Perspect"},{"key":"9728_CR64","doi-asserted-by":"publisher","first-page":"3735","DOI":"10.1016\/0006-2952(85)90239-4","volume":"34","author":"H Schramm","year":"1985","unstructured":"Schramm H, Robertson LW, Oesch F (1985) Differential regulation of hepatic glutathione transferase and glutathione peroxidase activities in the rat. Biochem Pharmacol 34:3735\u20133739","journal-title":"Biochem Pharmacol"},{"key":"9728_CR65","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/0378-4274(86)90103-7","volume":"30","author":"RF Seegal","year":"1986","unstructured":"Seegal RF, Brosch KO, Bush B (1986) Polychlorinated biphenyls produce regional alterations of dopamine metabolism in rat brain. Toxicol Lett 30:197\u2013202","journal-title":"Toxicol Lett"},{"key":"9728_CR66","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/0300-483X(94)90054-X","volume":"86","author":"RF Seegal","year":"1994","unstructured":"Seegal RF, Bush B, Brosch KO (1994) Decreases in dopamine concentrations in adult, non-human primate brain persist following removal from polychlorinated biphenyls. Toxicology 86:71\u201387","journal-title":"Toxicology"},{"key":"9728_CR67","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1006\/taap.1997.8226","volume":"146","author":"RF Seegal","year":"1997","unstructured":"Seegal RF, Brosch KO, Okoniewski RJ (1997) Effects of in utero and lactational exposure of the laboratory rat to 2,4,2\u2032,4\u2032- and 3,4,3\u2032,4\u2032-tetrachlorobiphenyl on dopamine function. Toxicol Appl Pharmacol 146:95\u2013103","journal-title":"Toxicol Appl Pharmacol"},{"key":"9728_CR68","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1093\/toxsci\/kfi174","volume":"86","author":"RF Seegal","year":"2005","unstructured":"Seegal RF, Brosch KO, Okoniewski RJ (2005) Coplanar PCB congeners increase uterine weight and frontal cortical dopamine in the developing rat: implications for developmental neurotoxicity. Toxicol Sci 86:125\u2013131","journal-title":"Toxicol Sci"},{"issue":"2","key":"9728_CR69","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/j.nbd.2010.01.009","volume":"38","author":"RF Seegal","year":"2010","unstructured":"Seegal RF, Marek KL, Seibyl JP, Jennings DL, Molho ES, Higgins DS, Factor SA, Fitzgerald EF, Hills EA, Korrick SA, Wolff MS, Haase RF, Todd AC, Parsons P, McCaffrey RJ (2010) Occupational exposure to PCBs reduces striatal dopamine transporter densities only in women: a beta-CIT imaging study. Neurobiol Dis 38(2): 219\u2013225","journal-title":"Neurobiol Dis"},{"key":"9728_CR70","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1097\/01.ede.0000190707.51536.2b","volume":"17","author":"K Steenland","year":"2006","unstructured":"Steenland K, Hein MJ, Cassinelli RT, Prince MM, Nilsen NB, Whelan EA et al (2006) Polychlorinated biphenyls and neurodegenerative disease mortality in an occupational cohort. Epidemiology 17:8\u201313","journal-title":"Epidemiology"},{"issue":"1","key":"9728_CR71","first-page":"457","volume":"138","author":"M Stegman","year":"2014","unstructured":"Stegman M, Curran CP, Infante SK, Kromme M, Hays B, Taylor K, Garber H, Lang A (2014) Assessing genetic susceptibility to motor function deficits following developmental exposure to polychlorinated biphenyls. Toxicol Sci Supp 138(1):457\u2013458","journal-title":"Toxicol Sci Supp"},{"issue":"1","key":"9728_CR72","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/S0892-0362(99)00056-2","volume":"22","author":"P Stewart","year":"2000","unstructured":"Stewart P, Reihman J, Lonky E, Darvill T, Pagano J (2000) Prenatal PCB exposure and neonatal behavioral assessment scale (NBAS) performance. Neurotoxicol Teratol 22(1):21\u201329","journal-title":"Neurotoxicol Teratol"},{"key":"9728_CR73","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1111\/j.1471-4159.2007.05049.x","volume":"104","author":"M Takahashi","year":"2008","unstructured":"Takahashi M, Negishi T, Tashior T (2008) Identification of genes mediating thyroid hormone action in the developing mouse cerebellum. J Neurochem 104:640\u2013652","journal-title":"J Neurochem"},{"key":"9728_CR74","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/j.tox.2011.08.001","volume":"289","author":"S Takeuchi","year":"2011","unstructured":"Takeuchi S, Shiraishi F, Kitamura S, Kuroki H, Jin K, Kojima H (2011) Characterization of steroid hormone receptor activities in 100 hydroxylated polychlorinated biphenyls, including congeners identified in humans. Toxicology 289:112\u2013121","journal-title":"Toxicology"},{"key":"9728_CR102","unstructured":"Ulbrich B, Stahlmann R (2004) Developmental toxicity of polychlorinated biphenyls (PCBs): a systematic review of experimental data. Arch Toxicol 78:252\u2013268"},{"key":"9728_CR75","unstructured":"United Nations Environmental Program (UNEP) (2001). Stockholm convention on persistent organic pollutants. http:\/\/chm.pops.int\/TheConvention\/Overview\/tabid\/3351\/Default.aspx"},{"key":"9728_CR103","doi-asserted-by":"crossref","unstructured":"van den Berg M, Birnbaum LS, Denison M, De VM, Farland W, Feeley M et al (2006) The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds. Toxicol Sci 93:223\u2013241","DOI":"10.1093\/toxsci\/kfl055"},{"key":"9728_CR76","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1016\/j.neuroscience.2015.09.025","volume":"310","author":"SE Van Dine","year":"2015","unstructured":"Van Dine SE, Siu NY, Toia A, Cuoco JA, Betz AJ, Bolivar VJ, Torres G, Ramos RL (2015) Spontaneous malformations of the cerebellar vermis: prevalence, inheritance, and relationship to lobule\/fissure organization in the C57BL\/6 lineage. Neuroscience 310:242\u2013251","journal-title":"Neuroscience"},{"key":"9728_CR77","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1289\/ehp.98106775","volume":"106","author":"BM Van den Berg","year":"1998","unstructured":"Van den Berg BM, Birnbaum L, Bosveld AT, Brunstrom B, Cook P, Feeley M et al (1998) Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife. Environ Health Perspect 106:775\u2013792","journal-title":"Environ Health Perspect"},{"key":"9728_CR78","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1289\/ehp.02110343","volume":"110","author":"P van den Hurk","year":"2002","unstructured":"van den Hurk P, Kubiczak GA, Lehmler HJ, James MO (2002) Hydroxylated polychlorinated biphenyls as inhibitors of the sulfation and glucuronidation of 3-hydroxy-benzo[a]pyrene. Environ Health Perspect 110:343\u2013348","journal-title":"Environ Health Perspect"},{"key":"9728_CR79","doi-asserted-by":"publisher","first-page":"2003","DOI":"10.1093\/carcin\/14.10.2003","volume":"14","author":"JP Vanden Heuvel","year":"1993","unstructured":"Vanden Heuvel JP, Clark GC, Thompson CL, McCoy Z, Miller CR, Lucier GW et al (1993) CYP1A1 mRNA levels as a human exposure biomarker: use of quantitative polymerase chain reaction to measure CYP1A1 expression in human peripheral blood lymphocytes. Carcinogenesis 14:2003\u20132006","journal-title":"Carcinogenesis"},{"key":"9728_CR80","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1067\/mpd.2002.119625","volume":"140","author":"HJ Vreugdenhil","year":"2002","unstructured":"Vreugdenhil HJ, Lanting CI, Mulder PG, Boersma ER, Weisglas-Kuperus N (2002) Effects of prenatal PCB and dioxin background exposure on cognitive and motor abilities in Dutch children at school age. J Pediatr 140:48\u201356","journal-title":"J Pediatr"},{"issue":"12","key":"9728_CR81","doi-asserted-by":"publisher","first-page":"E2735","DOI":"10.1210\/jc.2014-2629","volume":"99","author":"TL Wadzinski","year":"2014","unstructured":"Wadzinski TL, Geromini K, McKinley Brewer J, Bansal R, Abdelouahab N, Langlois MF, Takser L, Zoeller RT (2014) Endocrine disruption in human placenta: expression of the dioxin-inducible enzyme, CYP1A1, is correlated with that of thyroid hormone-regulated genes. J Clin Endocrinol Metab 99(12):E2735\u2013E2743","journal-title":"J Clin Endocrinol Metab"},{"issue":"13","key":"9728_CR82","doi-asserted-by":"publisher","first-page":"1659","DOI":"10.1002\/mds.25217","volume":"27","author":"MG Weisskopf","year":"2012","unstructured":"Weisskopf MG, Knekt P, O\u2019Reilly EJ, Lyytinen J, Reunanen A, Laden F, Altshul L, Ascherio A (2012) Polychlorinated biphenyls in prospectively collected serum and Parkinson\u2019s disease risk. Mov Disord 27(13):1659\u20131665","journal-title":"Mov Disord"},{"issue":"1\u20132","key":"9728_CR83","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.mrrev.2007.11.002","volume":"659","author":"M Wilhelm","year":"2008","unstructured":"Wilhelm M, Wittsiepe J, Lemm F, Ranft U, Kr\u00e4mer U, F\u00fcrst P, R\u00f6seler SC, Greshake M, Im\u00f6hl M, Eberwein G, Rauchfuss K, Kraft M, Winneke G (2008) The Duisburg birth cohort study: influence of the prenatal exposure to PCDD\/Fs and dioxin-like PCBs on thyroid hormone status in newborns and neurodevelopment of infants until the age of 24 months. Mutat Res 659(1\u20132):83\u201392","journal-title":"Mutat Res"},{"key":"9728_CR84","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1111\/j.1365-2826.2004.01243.x","volume":"16","author":"RT Zoeller","year":"2004","unstructured":"Zoeller RT, Rovett J (2004) Timing of thyroid hormone action in the developing brain: clinical observations and experimental findings. J Neuroendocrinol 16:809\u2013818","journal-title":"J Neuroendocrinol"}],"container-title":["Mammalian Genome"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00335-017-9728-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00335-017-9728-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00335-017-9728-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,29]],"date-time":"2024-06-29T06:12:00Z","timestamp":1719641520000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00335-017-9728-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,2]]},"references-count":85,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["9728"],"URL":"https:\/\/doi.org\/10.1007\/s00335-017-9728-1","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/194472","asserted-by":"object"}]},"ISSN":["0938-8990","1432-1777"],"issn-type":[{"value":"0938-8990","type":"print"},{"value":"1432-1777","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,2]]},"assertion":[{"value":"14 September 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 November 2017","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 December 2017","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The datasets for all figures and tables in this article are available from the corresponding author on reasonable request.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Data availability"}},{"value":"All applicable international, national, and\/or institutional guidelines for the care and use of animals were followed, and all protocols were approved by the Northern Kentucky University Institutional Animal Care and Use Committee.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Animal welfare"}}]}}