{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:20:20Z","timestamp":1786980020533,"version":"build-2736575974"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2011,11,5]],"date-time":"2011-11-05T00:00:00Z","timestamp":1320451200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Urol"],"published-print":{"date-parts":[[2012,8]]},"DOI":"10.1007\/s00345-011-0785-x","type":"journal-article","created":{"date-parts":[[2011,11,4]],"date-time":"2011-11-04T00:30:26Z","timestamp":1320366626000},"page":"457-464","source":"Crossref","is-referenced-by-count":32,"title":["Global concepts of bladder pain syndrome (interstitial cystitis)"],"prefix":"10.1007","volume":"30","author":[{"given":"J\u00f8rgen","family":"Nordling","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus","family":"Fall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Hanno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2011,11,5]]},"reference":[{"issue":"Supplement","key":"785_CR1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1442-2042.10.s1.1.x","volume":"10","author":"T Ueda","year":"2003","unstructured":"Ueda T, Sant G, Hanno P, Yoshimura N (2003) International consultation on interstitial cystitis Japan. Int J Urol 10(Supplement):1\u201370","journal-title":"Int J Urol"},{"issue":"5","key":"785_CR2","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.eururo.2003.11.021","volume":"45","author":"J Nordling","year":"2004","unstructured":"Nordling J, Anjum FH, Bade JJ, Bouchelouche K, Bouchelouche P, Cervigni M et al (2004) Primary evaluation of patients suspected of having interstitial cystitis (IC). Eur Urol 45(5):662\u2013669","journal-title":"Eur Urol"},{"issue":"1","key":"785_CR3","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.eururo.2007.09.019","volume":"53","author":"JP Merwe van de","year":"2008","unstructured":"van de Merwe JP, Nordling J, Bouchelouche P, Bouchelouche K, Cervigni M, Daha LK et al (2008) Diagnostic criteria, classification, and nomenclature for painful bladder syndrome\/interstitial cystitis: an ESSIC proposal. Eur Urol 53(1):60\u201367","journal-title":"Eur Urol"},{"issue":"2","key":"785_CR4","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/S0022-5347(01)61948-7","volume":"161","author":"PM Hanno","year":"1999","unstructured":"Hanno PM, Landis JR, Matthews-Cook Y, Kusek J, Nyberg L Jr (1999) The diagnosis of interstitial cystitis revisited: lessons learned from the national institutes of health interstitial cystitis database study. J Urol 161(2):553\u2013557","journal-title":"J Urol"},{"key":"785_CR5","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1002\/nau.10052","volume":"21","author":"PH Abrams","year":"2002","unstructured":"Abrams PH, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U et al (2002) The standardisation of terminology of lower urinary tract function: report from the standardisation sub-committee of the international continence society. Neurourol Urodyn 21:167\u2013178","journal-title":"Neurourol Urodyn"},{"issue":"6","key":"785_CR6","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1016\/j.urology.2006.01.086","volume":"67","author":"JW Warren","year":"2006","unstructured":"Warren JW, Meyer WA, Greenberg P, Horne L, Diggs C, Tracy JK (2006) Using the international continence society\u2019s definition of painful bladder syndrome. Urology 67(6):1138\u20131142","journal-title":"Urology"},{"issue":"1","key":"785_CR7","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.eururo.2007.10.010","volume":"53","author":"AP Baranowski","year":"2008","unstructured":"Baranowski AP, Abrams P, Berger RE, Buffington CA, de Williams ACC, Hanno P et al (2008) Urogenital pain: time to accept a new approach to phenotyping and, as a consequence, management. Eur Urol 53(1):33\u201336","journal-title":"Eur Urol"},{"issue":"1","key":"785_CR8","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1002\/nau.20847","volume":"29","author":"P Hanno","year":"2010","unstructured":"Hanno P, Lin A, Nordling J, Nyberg L, van Ophoven A, Ueda T et al (2010) Bladder pain syndrome committee of the international consultation on incontinence. Neurourol Urodyn 29(1):191\u2013198","journal-title":"Neurourol Urodyn"},{"issue":"1","key":"785_CR9","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1111\/j.1442-2042.2007.01907.x","volume":"15","author":"Y Homma","year":"2008","unstructured":"Homma Y (2008) Lower urinary tract symptomatology: Its definition and confusion. Int J Urol 15(1):35\u201343","journal-title":"Int J Urol"},{"issue":"7","key":"785_CR10","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1111\/j.1442-2042.2009.02326.x","volume":"16","author":"Y Homma","year":"2009","unstructured":"Homma Y, Ueda T, Tomoe H, Lin AT, Kuo HC, Lee MH et al (2009) Clinical guidelines for interstitial cystitis and hypersensitive bladder syndrome. Int J Urol 16(7):597\u2013615","journal-title":"Int J Urol"},{"issue":"1","key":"785_CR11","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.mcna.2010.08.014","volume":"95","author":"P Hanno","year":"2011","unstructured":"Hanno P, Nordling J, Fall M (2011) Bladder pain syndrome. Med Clin North Am 95(1):55\u201373","journal-title":"Med Clin North Am"},{"issue":"1","key":"785_CR12","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.eururo.2009.08.020","volume":"57","author":"M Fall","year":"2010","unstructured":"Fall M, Baranowski AP, Elneil S, Engeler D, Hughes J, Messelink EJ et al (2010) EAU guidelines on chronic pelvic pain. Eur Urol 57(1):35\u201348","journal-title":"Eur Urol"},{"key":"785_CR13","unstructured":"[No authors listed] (1979) Pain terms: a list with definitions and notes on usage. Recommended by the IASP subcommittee on taxonomy. Pain 6(3):249"},{"issue":"5","key":"785_CR14","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1111\/j.1526-4637.2005.00061.x","volume":"6","author":"J Raskin","year":"2005","unstructured":"Raskin J, Pritchett YL, Wang F, D\u2019Souza DN, Waninger AL, Iyengar S et al (2005) A double-blind, randomized multicenter trial comparing duloxetine with placebo in the management of diabetic peripheral neuropathic pain. Pain Med 6(5):346\u2013356","journal-title":"Pain Med"},{"key":"785_CR15","doi-asserted-by":"crossref","unstructured":"Lunn MP, Hughes RA, Wiffen PJ (2009) Duloxetine for treating painful neuropathy or chronic pain. Cochrane Database Syst Rev (4):CD007115","DOI":"10.1002\/14651858.CD007115.pub2"},{"key":"785_CR16","unstructured":"Neuropathic pain. National Institute of Health and Clinical Excellence (2010) Clinical guideline 96. http:\/\/www.nice.org.uk"},{"issue":"3","key":"785_CR17","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/S0022-5347(17)43242-3","volume":"138","author":"A Fritjofsson","year":"1987","unstructured":"Fritjofsson A, Fall M, Juhlin R, Persson BE, Ruutu M (1987) Treatment of ulcer and nonulcer interstitial cystitis with sodium pentosanpolysulfate: a multicenter trial. J Urol 138(3):508\u2013512","journal-title":"J Urol"},{"issue":"3","key":"785_CR18","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/S0022-5347(17)43241-1","volume":"138","author":"M Holm-Bentzen","year":"1987","unstructured":"Holm-Bentzen M, Jacobsen F, Nerstrom B, Lose G, Kristensen JK, Pedersen RH et al (1987) A prospective double-blind clinically controlled multicenter trial of sodium pentosanpolysulfate in the treatment of interstitial cystitis and related painful bladder disease. J Urol 138(3):503\u2013507","journal-title":"J Urol"},{"issue":"1","key":"785_CR19","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0022-5347(17)50948-9","volume":"130","author":"CL Parsons","year":"1983","unstructured":"Parsons CL, Schmidt JD, Pollen JJ (1983) Successful treatment of interstitial cystitis with sodium pentosanpolysulfate. J Urol 130(1):51\u201353","journal-title":"J Urol"},{"issue":"6","key":"785_CR20","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/0090-4295(90)80116-5","volume":"35","author":"SG Mulholland","year":"1990","unstructured":"Mulholland SG, Hanno P, Parsons CL, Sant GR, Staskin DR (1990) Pentosan polysulfate sodium for therapy of interstitial cystitis. A double-blind placebo-controlled clinical study. Urology 35(6):552\u2013558","journal-title":"Urology"},{"issue":"3","key":"785_CR21","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/S0022-5347(17)35629-X","volume":"150","author":"CL Parsons","year":"1993","unstructured":"Parsons CL, Benson G, Childs SJ, Hanno P, Sant GR, Webster G (1993) A quantitatively controlled method to study prospectively interstitial cystitis and demonstrate the efficacy of pentosanpolysulfate. J Urol 150(3):845\u2013848","journal-title":"J Urol"},{"issue":"1","key":"785_CR22","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0094-0143(21)00600-5","volume":"21","author":"TC Theoharides","year":"1994","unstructured":"Theoharides TC (1994) Hydroxyzine in the treatment of interstitial cystitis. Urol Clin North Am 21(1):113\u2013119","journal-title":"Urol Clin North Am"},{"issue":"5A Suppl","key":"785_CR23","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/S0090-4295(97)00182-9","volume":"49","author":"TC Theoharides","year":"1997","unstructured":"Theoharides TC, Sant GR (1997) Hydroxyzine therapy for interstitial cystitis. Urology 49(5A Suppl):108\u2013110","journal-title":"Urology"},{"key":"785_CR24","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1046\/j.1464-410x.2001.02031.x","volume":"87","author":"R Thilagarajah","year":"2001","unstructured":"Thilagarajah R, Witherow RO, Walker MM (2001) Oral cimetidine gives effective symptom relief in painful bladder disease: a prospective, randomized, double-blind placebo-controlled trial. BJU Int 87:207\u2013212","journal-title":"BJU Int"},{"issue":"3","key":"785_CR25","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1097\/01.ju.0000083020.06212.3d","volume":"170","author":"GR Sant","year":"2003","unstructured":"Sant GR, Propert KJ, Hanno PM, Burks D, Culkin D, Diokno AC et al (2003) A pilot clinical trial of oral pentosan polysulfate and oral hydroxyzine in patients with interstitial cystitis. J Urol 170(3):810\u2013815","journal-title":"J Urol"},{"issue":"1","key":"785_CR26","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.juro.2009.08.133","volume":"183","author":"JC Nickel","year":"2010","unstructured":"Nickel JC, Tripp DA, Pontari M, Moldwin R, Mayer R, Carr LK et al (2010) Psychosocial phenotyping in women with interstitial cystitis\/painful bladder syndrome: a case control study. J Urol 183(1):167\u2013172","journal-title":"J Urol"},{"issue":"1","key":"785_CR27","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/S0022-5347(17)41478-9","volume":"140","author":"R Perez-Marrero","year":"1988","unstructured":"Perez-Marrero R, Emerson LE, Feltis JT (1988) A controlled study of dimethyl sulfoxide in interstitial cystitis. J Urol 140(1):36\u201339","journal-title":"J Urol"},{"key":"785_CR28","volume-title":"Diseases of the bladder and urethra in women","author":"AJC Skene","year":"1887","unstructured":"Skene AJC (1887) Diseases of the bladder and urethra in women. William Wood, New York"},{"key":"785_CR29","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1056\/NEJM191505061721802","volume":"172","author":"GL Hunner","year":"1915","unstructured":"Hunner GL (1915) A rare type of bladder ulcer in women; report of cases. Boston Med Surg J 172:660\u2013664","journal-title":"Boston Med Surg J"},{"issue":"1","key":"785_CR30","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0022-5347(17)43863-8","volume":"137","author":"M Fall","year":"1987","unstructured":"Fall M, Johansson SL, Aldenborg F (1987) Chronic interstitial cystitis: a heterogeneous syndrome. J Urol 137(1):35\u201338","journal-title":"J Urol"},{"issue":"6","key":"785_CR31","doi-asserted-by":"crossref","first-page":"2470","DOI":"10.1016\/S0022-5347(05)65006-9","volume":"167","author":"R Peeker","year":"2002","unstructured":"Peeker R, Fall M (2002) Toward a precise definition of interstitial cystitis: further evidence of differences in classic and nonulcer disease. J Urol 167(6):2470\u20132472","journal-title":"J Urol"},{"key":"785_CR32","unstructured":"Sant G, Meares E (1990) Interstitial cystitis: pathogenesis, diagnosis, and treatment. Infect Urol 24\u201330"},{"issue":"4","key":"785_CR33","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1016\/j.juro.2008.06.035","volume":"180","author":"R Braunstein","year":"2008","unstructured":"Braunstein R, Shapiro E, Kaye J, Moldwin R (2008) The role of cystoscopy in the diagnosis of Hunner\u2019s ulcer disease. J Urol 180(4):1383\u20131386","journal-title":"J Urol"},{"issue":"4","key":"785_CR34","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/0090-4295(78)90286-8","volume":"12","author":"EM Messing","year":"1978","unstructured":"Messing EM, Stamey TA (1978) Interstitial cystitis: early diagnosis, pathology, and treatment. Urology 12(4):381\u2013392","journal-title":"Urology"},{"key":"785_CR35","first-page":"137","volume-title":"Interstitial cystitis","author":"DA Nigro","year":"1997","unstructured":"Nigro DA, Wein AJ (1997) Interstitial cystitis: clinical and endoscopic features. In: Sant GR (ed) Interstitial cystitis. Lippincott-Raven, Philadelphia, pp 137\u2013142"},{"issue":"5","key":"785_CR36","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1016\/S0022-5347(01)62376-0","volume":"160","author":"JA Waxman","year":"1998","unstructured":"Waxman JA, Sulak PJ, Kuehl TJ (1998) Cystoscopic findings consistent with interstitial cystitis in normal women undergoing tubal ligation. J Urol 160(5):1663\u20131667","journal-title":"J Urol"},{"issue":"5","key":"785_CR37","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1016\/j.urology.2007.06.1153","volume":"70","author":"R Furuya","year":"2007","unstructured":"Furuya R, Masumori N, Furuya S, Oda T, Takahashi S, Takeuchi M (2007) Glomerulation observed during transurethral resection of the prostate for patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia is a common finding but no predictor of clinical outcome. Urology 70(5):922\u2013926","journal-title":"Urology"},{"issue":"5","key":"785_CR38","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/S0022-5347(17)49221-4","volume":"133","author":"M Fall","year":"1985","unstructured":"Fall M, Johansson SL, Vahlne A (1985) A clinicopathological and virological study of interstitial cystitis. J Urol 133(5):771\u2013773","journal-title":"J Urol"},{"issue":"6","key":"785_CR39","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1016\/S0022-5347(17)40201-1","volume":"143","author":"SL Johansson","year":"1990","unstructured":"Johansson SL, Fall M (1990) Clinical features and spectrum of light microscopic changes in interstitial cystitis. J Urol 143(6):1118\u20131124","journal-title":"J Urol"},{"issue":"6 Suppl 1","key":"785_CR40","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0090-4295(01)01129-3","volume":"57","author":"TC Theoharides","year":"2001","unstructured":"Theoharides TC, Kempuraj D, Sant GR (2001) Mast cell involvement in interstitial cystitis: a review of human and experimental evidence. Urology 57(6 Suppl 1):47\u201355","journal-title":"Urology"},{"issue":"3","key":"785_CR41","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/S0022-5347(05)67873-1","volume":"163","author":"R Peeker","year":"2000","unstructured":"Peeker R, Enerback L, Fall M, Aldenborg F (2000) Recruitment, distribution and phenotypes of mast cells in interstitial cystitis. J Urol 163(3):1009\u20131015","journal-title":"J Urol"},{"issue":"2","key":"785_CR42","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1111\/j.1464-410X.2008.07576.x","volume":"102","author":"MS Larsen","year":"2008","unstructured":"Larsen MS, Mortensen S, Nordling J, Horn T (2008) Quantifying mast cells in bladder pain syndrome by immunohistochemical analysis. BJU Int 102(2):204\u2013207","journal-title":"BJU Int"},{"issue":"5","key":"785_CR43","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1111\/j.1464-410X.1983.tb03356.x","volume":"55","author":"J Kastrup","year":"1983","unstructured":"Kastrup J, Hald T, Larsen S, Nielsen VG (1983) Histamine content and mast cell count of detrusor muscle in patients with interstitial cystitis and other types of chronic cystitis. Br J Urol 55(5):495\u2013500","journal-title":"Br J Urol"},{"issue":"5","key":"785_CR44","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/S0022-5347(17)49222-6","volume":"133","author":"M Fall","year":"1985","unstructured":"Fall M (1985) Conservative management of chronic interstitial cystitis: transcutaneous electrical nerve stimulation and transurethral resection. J Urol 133(5):774\u2013778","journal-title":"J Urol"},{"issue":"4 Suppl","key":"785_CR45","first-page":"31","volume":"29","author":"AM Shanberg","year":"1987","unstructured":"Shanberg AM, Malloy T (1987) Treatment of interstitial cystitis with neodymium: YAG laser. Urology 29(4 Suppl):31\u201333","journal-title":"Urology"},{"issue":"5","key":"785_CR46","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1007\/s001920070019","volume":"11","author":"R Peeker","year":"2000","unstructured":"Peeker R, Aldenborg F, Fall M (2000) Complete transurethral resection of ulcers in classic interstitial cystitis. Int Urogynecol J Pelvic Floor Dysfunct 11(5):290\u2013295","journal-title":"Int Urogynecol J Pelvic Floor Dysfunct"},{"issue":"2","key":"785_CR47","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/0306-4522(83)90153-7","volume":"10","author":"B Newson","year":"1983","unstructured":"Newson B, Dahlstrom A, Enerback L, Ahlman H (1983) Suggestive evidence for a direct innervation of mucosal mast cells. Neuroscience 10(2):565\u2013570","journal-title":"Neuroscience"},{"issue":"4","key":"785_CR48","first-page":"436","volume":"132","author":"B Garrelts von","year":"1966","unstructured":"von Garrelts B (1966) Interstitial cystitis: thirteen patients treated operatively with intestinal bladder substitutes. Acta Chir Scand 132(4):436\u2013443","journal-title":"Acta Chir Scand"},{"issue":"1","key":"785_CR49","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1159\/000281774","volume":"46","author":"MJ Kontturi","year":"1991","unstructured":"Kontturi MJ, Hellstrom PA, Tammela TL, Lukkarinen OA (1991) Colocystoplasty for the treatment of severe interstitial cystitis. Urol Int 46(1):50\u201354","journal-title":"Urol Int"},{"issue":"5","key":"785_CR50","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1097\/00005392-199805000-00018","volume":"159","author":"R Peeker","year":"1998","unstructured":"Peeker R, Aldenborg F, Fall M (1998) The treatment of interstitial cystitis with supratrigonal cystectomy and ileocystoplasty: difference in outcome between classic and nonulcer disease. J Urol 159(5):1479\u20131482","journal-title":"J Urol"},{"issue":"4","key":"785_CR51","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.urology.2007.05.028","volume":"70","author":"J Rossberger","year":"2007","unstructured":"Rossberger J, Fall M, Jonsson O, Peeker R (2007) Long-term results of reconstructive surgery in patients with bladder pain syndrome\/interstitial cystitis: subtyping is imperative. Urology 70(4):638\u2013642","journal-title":"Urology"}],"container-title":["World Journal of Urology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00345-011-0785-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00345-011-0785-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00345-011-0785-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T13:36:43Z","timestamp":1639489003000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00345-011-0785-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11,5]]},"references-count":51,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["785"],"URL":"https:\/\/doi.org\/10.1007\/s00345-011-0785-x","relation":{},"ISSN":["0724-4983","1433-8726"],"issn-type":[{"value":"0724-4983","type":"print"},{"value":"1433-8726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,11,5]]}}}