{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:20:21Z","timestamp":1786980021743,"version":"build-2736575974"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2015,5,31]],"date-time":"2015-05-31T00:00:00Z","timestamp":1433030400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World J Urol"],"published-print":{"date-parts":[[2016,2]]},"DOI":"10.1007\/s00345-015-1595-3","type":"journal-article","created":{"date-parts":[[2015,5,30]],"date-time":"2015-05-30T02:11:26Z","timestamp":1432951886000},"page":"189-195","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Efficacy and safety of a new device for intravesical thermochemotherapy in non-grade 3 BCG recurrent NMIBC: a phase I\u2013II study"],"prefix":"10.1007","volume":"34","author":[{"given":"Francesco","family":"Soria","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Milla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Fiorito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Pisano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Sogni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimiliano","family":"Di Marco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Pagliarulo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franco","family":"Dosio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Gontero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,5,31]]},"reference":[{"issue":"4","key":"1595_CR1","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.eururo.2013.06.003","volume":"64","author":"M Babjuk","year":"2013","unstructured":"Babjuk M, Burger M, Zigeuner R et al (2013) EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder: update 2013. Eur Urol 64(4):639\u2013653","journal-title":"Eur Urol"},{"key":"1595_CR2","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1586\/era.09.35","volume":"9","author":"FM Martin","year":"2009","unstructured":"Martin FM, Kamat AM (2009) Definition and management of patients with bladder cancer who fail BCG therapy. Expert Rev Anticancer Ther 9:815\u2013820","journal-title":"Expert Rev Anticancer Ther"},{"issue":"6","key":"1595_CR3","doi-asserted-by":"crossref","first-page":"2314","DOI":"10.1016\/j.juro.2007.09.003","volume":"178","author":"MC Hall","year":"2007","unstructured":"Hall MC, Chang SS, Dalbagni G et al (2007) Guideline for the management of nonmuscle invasive bladder cancer (stages Ta, T1 and Tis): 2007 update. J Urol 178(6):2314\u20132330","journal-title":"J Urol"},{"key":"1595_CR4","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.urolonc.2007.11.033","volume":"27","author":"SP Lerner","year":"2009","unstructured":"Lerner SP, Tangen CM, Sucharew H et al (2009) Failure to achieve a complete response to induction BCG therapy is associated with increased risk of disease worsening and death in patients with high risk non muscle invasive bladder cancer. Urol Oncol 27:155\u2013159","journal-title":"Urol Oncol"},{"key":"1595_CR5","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.urology.2007.09.050","volume":"71","author":"BL Gallagher","year":"2008","unstructured":"Gallagher BL, Joudi FN, Maymi JL et al (2008) Impact of previous bacilli Calmette-Guerin failure pattern on subsequent response to bacilli Calmette-Guerin plus interferon intravesical therapy. Urology 71:297\u2013301","journal-title":"Urology"},{"key":"1595_CR6","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1016\/j.eururo.2012.08.055","volume":"62","author":"DR Yates","year":"2012","unstructured":"Yates DR, Brausi MA, Catto JW et al (2012) Treatment options available for bacillus Calmette-Gu\u00e9rin failure in non-muscle-invasive bladder cancer. Eur Urol 62:1088\u20131096","journal-title":"Eur Urol"},{"issue":"5","key":"1595_CR7","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1016\/j.juro.2013.04.120","volume":"190","author":"IA Sternberg","year":"2013","unstructured":"Sternberg IA, Dalbagni G, Chen LY et al (2013) Intravesical gemcitabine for high risk, nonmuscle invasive bladder cancer after bacillus Calmette-Gu\u00e9rin treatment failure. J Urol 190(5):1686\u20131691","journal-title":"J Urol"},{"key":"1595_CR8","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1097\/01.ju.0000146274.85012.e1","volume":"173","author":"AG Heijden Van der","year":"2005","unstructured":"Van der Heijden AG, Verhaegh G, Jansen CF et al (2005) Effect of hyperthermia on the cytotoxicity of 4 chemotherapeutic agents currently used for the treatment of transitional cell carcinoma of the bladder: an in vitro study. J Urol 173:1375\u20131380","journal-title":"J Urol"},{"key":"1595_CR9","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1016\/S0022-5347(01)66225-6","volume":"155","author":"R Colombo","year":"1996","unstructured":"Colombo R, Da Pozzo LF, Lev A et al (1996) Neoadjuvant combined microwave induced local hyperthermia and topical chemotherapy versus chemotherapy alone for superficial bladder cancer. J Urol 155:1227\u20131232","journal-title":"J Urol"},{"issue":"6","key":"1595_CR10","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1111\/j.1464-410X.2010.09654.x","volume":"107","author":"R Colombo","year":"2011","unstructured":"Colombo R, Salonia A, Leib Z et al (2011) Long-term outcomes of a randomized controlled trial comparing thermochemotherapy with mitomycin-C alone as adjuvant treatment for non-muscle-invasive bladder cancer (NMIBC). BJU Int 107(6):912\u2013918","journal-title":"BJU Int"},{"key":"1595_CR11","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1016\/j.juro.2009.06.017","volume":"182","author":"O Nativ","year":"2009","unstructured":"Nativ O, Witjes JA, Hendricksen K et al (2009) Combined thermo-chemotherapy for recurrent bladder cancer after bacillus Calmette-Guerin. J Urol 182:1313\u20131317","journal-title":"J Urol"},{"key":"1595_CR12","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.eururo.2011.04.023","volume":"60","author":"RJ Lammers","year":"2011","unstructured":"Lammers RJ, Witjes JA, Inman BA et al (2011) The role of a combined regimen with intravesical chemotherapy and hyperthermia in the management of non-muscle-invasive bladder cancer: a systematic review. Eur Urol 60:81\u201393","journal-title":"Eur Urol"},{"issue":"6","key":"1595_CR13","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1308\/003588414X13946184901001","volume":"96","author":"SE Slater","year":"2014","unstructured":"Slater SE, Patel P, Viney R et al (2014) The effects and effectiveness of electromotive drug administration and chemohyperthermia for treating non-muscle invasive bladder cancer. Ann R Coll Surg Engl 96(6):415\u2013419","journal-title":"Ann R Coll Surg Engl"},{"issue":"2","key":"1595_CR14","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S1040-8428(03)00076-3","volume":"47","author":"R Colombo","year":"2003","unstructured":"Colombo R, Salonia A, Da Pozzo LF et al (2003) Combination of intravesical chemotherapy and hyperthermia for the treatment of superficial bladder cancer: preliminary clinical experience. Crit Rev Oncol Hematol 47(2):127\u2013139","journal-title":"Crit Rev Oncol Hematol"},{"issue":"3","key":"1595_CR15","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/S1053-4296(03)00031-6","volume":"13","author":"A Trotti","year":"2003","unstructured":"Trotti A, Colevas AD, Setser A et al (2003) CTCAE v3.0: development of a comprehensive grading system for the adverse effects of cancer treatment. Semin Radiat Oncol 13(3):176\u2013181","journal-title":"Semin Radiat Oncol"},{"issue":"3","key":"1595_CR16","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1007\/s00280-014-2381-4","volume":"73","author":"P Milla","year":"2014","unstructured":"Milla P, Fiorito C, Soria F et al (2014) Intravesical thermo-chemotherapy based on conductive heat: a first pharmacokinetic study with mitomycin C in superficial transitional cell carcinoma patients. Cancer Chemother Pharmacol 73(3):503\u2013509","journal-title":"Cancer Chemother Pharmacol"},{"issue":"2","key":"1595_CR17","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.juro.2014.02.2573","volume":"192","author":"AM Kamat","year":"2014","unstructured":"Kamat AM, Witjes JA, Brausi M et al (2014) Defining and treating the spectrum of intermediate risk nonmuscle invasive bladder cancer. J Urol 192(2):305\u2013315","journal-title":"J Urol"},{"key":"1595_CR18","first-page":"CD00929","volume":"1","author":"G Jones","year":"2012","unstructured":"Jones G, Cleves A, Wilt TJ et al (2012) Intravesical gemcitabine for non-muscle invasive bladder cancer (Review). Cochrane Database Syst Rev 1:CD00929","journal-title":"Cochrane Database Syst Rev"},{"issue":"4","key":"1595_CR19","doi-asserted-by":"crossref","first-page":"31","DOI":"10.3810\/hp.2013.10.1078","volume":"41","author":"SM Prasad","year":"2013","unstructured":"Prasad SM, Eyre S, Loughlin KR (2013) Salvage combination intravesical immunotherapy with Bacillus Calmette-Gu\u00e9rin and interferon-\u03b12B: impact on recurrence, progression, and survival. Hosp Pract (1995) 41(4):31-39","journal-title":"Hosp Pract (1995)"},{"key":"1595_CR20","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1080\/095530097143392","volume":"72","author":"J Dahm-Daphi","year":"1997","unstructured":"Dahm-Daphi J, Brammer I, Dikomey E (1997) Heat effects on the repair of DNA double strand breaks in CHO cells. Int J Radiat Biol 72:171\u2013179","journal-title":"Int J Radiat Biol"},{"key":"1595_CR21","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1046\/j.0306-5251.2001.01449.x","volume":"52","author":"R Paroni","year":"2001","unstructured":"Paroni R et al (2001) Effect of local hyperthermia of the bladder on mitomycin C pharmacokinetics during intravesical chemotherapy for the treatment of superficial transitional cell carcinoma. Br J Clin Pharmacol 52:273\u2013278","journal-title":"Br J Clin Pharmacol"},{"key":"1595_CR22","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s00345-009-0384-2","volume":"27","author":"JA Witjes","year":"2009","unstructured":"Witjes JA, Hendricksen K, Gofrit O et al (2009) Intravesical hyperthermia and mitomycin-C for carcinoma in situ of the urinary bladder: experience of the European Synergo\u00ae working party. World J Urol 27:319\u2013324","journal-title":"World J Urol"},{"key":"1595_CR23","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/S0022-5347(01)67613-4","volume":"153","author":"R Colombo","year":"1995","unstructured":"Colombo R, Lev A, Da Pozzo LF et al (1995) A new approach using local combined microwave hyperthermia and chemotherapy in superficial transitional bladder carcinoma treatment. J Urol 153:959\u2013963","journal-title":"J Urol"}],"container-title":["World Journal of Urology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00345-015-1595-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00345-015-1595-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00345-015-1595-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T09:40:21Z","timestamp":1559036421000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00345-015-1595-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5,31]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["1595"],"URL":"https:\/\/doi.org\/10.1007\/s00345-015-1595-3","relation":{},"ISSN":["0724-4983","1433-8726"],"issn-type":[{"value":"0724-4983","type":"print"},{"value":"1433-8726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5,31]]}}}