{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T17:48:09Z","timestamp":1780508889748,"version":"3.54.1"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2018,5,3]],"date-time":"2018-05-03T00:00:00Z","timestamp":1525305600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World J Urol"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1007\/s00345-018-2314-7","type":"journal-article","created":{"date-parts":[[2018,5,3]],"date-time":"2018-05-03T04:32:09Z","timestamp":1525321929000},"page":"1651-1656","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Randomized clinical trial between polyacrylate-polyalcohol copolymer (PPC) and dextranomer-hyaluronic acid copolymer (Dx\/HA) as bulking agents for endoscopic treatment of primary vesicoureteral reflux (VUR)"],"prefix":"10.1007","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0744-562X","authenticated-orcid":false,"given":"L.","family":"Garc\u00eda-Aparicio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Bl\u00e1zquez-G\u00f3mez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"P\u00e9rez-Bert\u00f3lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Arboleda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Soria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.","family":"Tarrado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,5,3]]},"reference":[{"key":"2314_CR1","doi-asserted-by":"publisher","first-page":"2413","DOI":"10.1097\/01.ju.0000127754.79866.7f","volume":"171","author":"AJ Kirsch","year":"2004","unstructured":"Kirsch AJ, Perez-Brayfield M, Smith EA, Scherz H (2004) The modified STING procedure to correct vesicoureteral reflux: improved results with submucosal implantation within the intramural ureter. J Urol 171:2413","journal-title":"J Urol"},{"key":"2314_CR2","doi-asserted-by":"publisher","first-page":"1887","DOI":"10.1016\/S0022-5347(05)65713-8","volume":"166","author":"G L\u00e4ckgren","year":"2001","unstructured":"L\u00e4ckgren G, W\u00e4hlin N (2001) Sk\u20acoldenberg E, Stenberg A. Long-term followup of children treated with dextranomer\/hyaluronic acid copolymer for vesicoureteral reflux. J Urol 166:1887\u20131892","journal-title":"J Urol"},{"issue":"10","key":"2314_CR3","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1016\/j.acuro.2016.02.007","volume":"40","author":"L Garc\u00eda-Aparicio","year":"2016","unstructured":"Garc\u00eda-Aparicio L, Bl\u00e1zquez-G\u00f3mez E, Vila Santandreu A, Camacho JA, Vila-Cots J, Ramos M et al (2016) Routine delayed voiding cystourethography after successful endoscopic treatment with Dx\/HA of vesicoureteral reflux. Is it necessary? Actas Urol Esp 40(10):635\u2013639","journal-title":"Actas Urol Esp"},{"key":"2314_CR4","doi-asserted-by":"publisher","first-page":"1869","DOI":"10.1016\/j.juro.2008.12.005","volume":"181","author":"EK Lee","year":"2009","unstructured":"Lee EK, Gatti JM, Demarco RT et al (2009) Long-term follow-up of dextranomer\/hyaluronic acid injection for vesicoureteral reflux: late failure warrants continued follow-up. J Urol 181:1869\u20131874","journal-title":"J Urol"},{"key":"2314_CR5","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1016\/j.juro.2009.10.047","volume":"183","author":"M Ormaechea","year":"2010","unstructured":"Ormaechea M, Ruiz E, Denes E et al (2010) New tissue bulking agent (polyacrylate polyalcohol) for treating vesicoureteral reflux: preliminary results in children. J Urol 183:714\u2013717","journal-title":"J Urol"},{"key":"2314_CR6","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1016\/j.jpurol.2010.11.010","volume":"7","author":"B Chertin","year":"2011","unstructured":"Chertin B, Arafeh WA, Zeldin A et al (2011) Preliminary data on endoscopic treatment of vesicoureteric reflux with polyacrylate polyalcohol copolymer (Vantris): surgical outcome following single injection. J Pediatr Urol 7:654\u2013657","journal-title":"J Pediatr Urol"},{"key":"2314_CR7","doi-asserted-by":"publisher","first-page":"1032","DOI":"10.1016\/j.jpurol.2014.02.016","volume":"10","author":"F Sharifiaghdas","year":"2014","unstructured":"Sharifiaghdas F, Tajalli F, Otukesh H, Shamsabadi RH (2014) Endoscopic correction of primary VUR by using polyacrylate polyalcohol copolymer (Vantris) in young girls: 2-year follow-up. J Pediatr Urol 10:1032\u20131369","journal-title":"J Pediatr Urol"},{"key":"2314_CR8","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/j.urology.2013.01.024","volume":"82","author":"B Chertin","year":"2013","unstructured":"Chertin B, Arafeh WA, Zeldin A, Ostrovsky IA, Kocherov S (2013) Endoscopic correction of VUR using Vantris as a new non-biodegradable tissue augmenting substance: three years of prospective follow-up. Urology 82:201\u2013204","journal-title":"Urology"},{"issue":"4","key":"2314_CR9","doi-asserted-by":"publisher","first-page":"256.e1","DOI":"10.1016\/j.jpurol.2016.04.006","volume":"12","author":"S Warchol","year":"2016","unstructured":"Warchol S, Krzemien G, Szmigielska A, Bombinski P, Brzewski M, Dudek-Warchol T (2016) Comparison of results of endoscopic correction of vesicoureteral reflux in children using two bulking substances: dextranomer\/hyaluronic acid copolymer (Deflux) versus polyacrylate-polyalcohol copolymer (Vantris). J Pediatr Urol 12(4):256.e1\u2013256.e4","journal-title":"J Pediatr Urol"},{"issue":"3","key":"2314_CR10","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1590\/S1677-5538.IBJU.2015.0274","volume":"42","author":"H Ta\u015fkinlar","year":"2016","unstructured":"Ta\u015fkinlar H, Avlan D, Bahadir GB, Deliba\u015f A, Nayci A (2016) The outcomes of two different bulking agents (dextranomer hyaluronic acid copolymer and polyacrylate-polyalcohol copolymer) in the treatment of primary vesico-ureteral reflux. Int Braz J Urol 42(3):514\u2013520","journal-title":"Int Braz J Urol"},{"issue":"10","key":"2314_CR11","doi-asserted-by":"publisher","first-page":"1711","DOI":"10.1016\/j.jpedsurg.2016.03.013","volume":"51","author":"C Kocaoglu","year":"2016","unstructured":"Kocaoglu C (2016) Endoscopic treatment of grades IV and V vesicoureteral reflux with two bulking substances: dextranomer hyaluronic acid copolymer versus polyacrylate polyalcohol copolymer in children. J Pediatr Surg 51(10):1711\u20131715","journal-title":"J Pediatr Surg"},{"issue":"9","key":"2314_CR12","doi-asserted-by":"publisher","first-page":"1496","DOI":"10.1016\/j.jpedsurg.2016.02.092","volume":"51","author":"SC Karakus","year":"2016","unstructured":"Karakus SC, User \u0130R, K\u0131l\u0131c BD, Ak\u00e7aer V, Ceylan H, Ozokutan BH (2016) The comparison of dextranomer\/hyaluronic acid and polyacrylate-polyalcohol copolymers in endoscopic treatment of vesicoureteral reflux. J Pediatr Surg 51(9):1496\u20131500","journal-title":"J Pediatr Surg"},{"issue":"5","key":"2314_CR13","first-page":"263","volume":"20","author":"E Matouschek","year":"1981","unstructured":"Matouschek E (1981) Treatment of vesicorenal reflux by transurethral teflon-injection (author\u2019s transl). Urol A 20(5):263\u2013264","journal-title":"Urol A"},{"issue":"4","key":"2314_CR14","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1016\/j.jpurol.2013.02.007","volume":"9","author":"L Garc\u00eda-Aparicio","year":"2013","unstructured":"Garc\u00eda-Aparicio L, Rodo J, Palazon P, Mart\u00edn O, Bl\u00e1zquez-G\u00f3mez E, Manzanares A et al (2013) Acute and delayed vesicoureteral obstruction after endoscopic treatment of primary vesicoureteral reflux with dextranomer\/hyaluronic acid copolymer: why and how to manage. J Pediatr Urol 9(4):493\u2013497","journal-title":"J Pediatr Urol"},{"issue":"4","key":"2314_CR15","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1016\/j.jpurol.2012.11.007","volume":"9","author":"F Alizadeh","year":"2013","unstructured":"Alizadeh F, Mazdak H, Khorrami MH, Khalighinejad P, Shoureshi P (2013) Postoperative ureteral obstruction after endoscopic treatment of vesicoureteral reflux with polyacrylate polyalcohol copolymer (Vantris\u00ae). J Pediatr Urol 9(4):488\u2013492","journal-title":"J Pediatr Urol"},{"issue":"3","key":"2314_CR16","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1016\/j.urology.2014.04.033","volume":"84","author":"S Kocherov","year":"2014","unstructured":"Kocherov S, Ulman I, Nikolaev S, Corbetta JP, Rudin Y, Slavkovic A et al (2014) Multicenter survey of endoscopic treatment of vesicoureteral reflux using polyacrylate-polyalcohol bulking copolymer (Vantris). Urology 84(3):689\u2013693","journal-title":"Urology"}],"container-title":["World Journal of Urology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00345-018-2314-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00345-018-2314-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00345-018-2314-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,2]],"date-time":"2019-05-02T19:08:55Z","timestamp":1556824135000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00345-018-2314-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,3]]},"references-count":16,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["2314"],"URL":"https:\/\/doi.org\/10.1007\/s00345-018-2314-7","relation":{},"ISSN":["0724-4983","1433-8726"],"issn-type":[{"value":"0724-4983","type":"print"},{"value":"1433-8726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,3]]},"assertion":[{"value":"26 February 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 April 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 May 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"We have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in this study were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. The study was approved by our Research Ethical Board number: 45-14.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"All patients included in the study signed the informed consent.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}