{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T23:08:37Z","timestamp":1793315317321,"version":"4.5.0"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World J Urol"],"DOI":"10.1007\/s00345-025-05575-8","type":"journal-article","created":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T23:01:50Z","timestamp":1743721310000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A systematic review and meta-analysis of alpha-adrenergic antagonists for the treatment of pain in chronic prostatitis"],"prefix":"10.1007","volume":"43","author":[{"given":"Anthony","family":"Carona","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Jacobson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Hildebolt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8006-4391","authenticated-orcid":false,"given":"Kevin","family":"Rowland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,1]]},"reference":[{"issue":"2","key":"5575_CR1","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1016\/S0090-4295(99)00205-8","volume":"54","author":"JC Nickel","year":"1999","unstructured":"Nickel JC, Nyberg LM, Hennenfent M (1999) Research guidelines for chronic prostatitis: consensus report from the first national institutes of health international prostatitis collaborative network. Urology 54(2):229\u2013233","journal-title":"Urology"},{"issue":"1","key":"5575_CR2","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1046\/j.1464-410x.2001.02259.x","volume":"88","author":"A Mehik","year":"2001","unstructured":"Mehik A et al (2001) Fears, sexual disturbances and personality features in men with prostatitis: a population-based cross-sectional study in Finland. BJU Int 88(1):35\u201338","journal-title":"BJU Int"},{"issue":"3","key":"5575_CR3","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1016\/S0022-5347(01)66359-6","volume":"155","author":"K Wenninger","year":"1996","unstructured":"Wenninger K et al (1996) Sickness impact of chronic nonbacterial prostatitis and its correlates. J Urol 155(3):965\u2013968","journal-title":"J Urol"},{"issue":"2","key":"5575_CR4","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1007\/s00345-003-0329-0","volume":"21","author":"JN Krieger","year":"2003","unstructured":"Krieger JN et al (2003) Epidemiology of prostatitis: new evidence for a world-wide problem. World J Urol 21(2):70\u201374","journal-title":"World J Urol"},{"issue":"4","key":"5575_CR5","doi-asserted-by":"publisher","first-page":"1224","DOI":"10.1016\/S0022-5347(01)63564-X","volume":"159","author":"MM Collins","year":"1998","unstructured":"Collins MM et al (1998) How common is prostatitis? A national survey of physician visits. J Urol 159(4):1224\u20131228","journal-title":"J Urol"},{"issue":"2","key":"5575_CR6","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1016\/j.eururo.2015.08.061","volume":"69","author":"G Magistro","year":"2016","unstructured":"Magistro G et al (2016) Contemporary management of chronic prostatitis\/chronic pelvic pain syndrome. Eur Urol 69(2):286\u2013297","journal-title":"Eur Urol"},{"issue":"10","key":"5575_CR7","first-page":"CD012552","volume":"10","author":"JV Franco","year":"2019","unstructured":"Franco JV et al (2019) Pharmacological interventions for treating chronic prostatitis\/chronic pelvic pain syndrome. Cochrane Database Syst Rev 10(10):CD012552","journal-title":"Cochrane Database Syst Rev"},{"issue":"10","key":"5575_CR8","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1007\/s40266-021-00890-2","volume":"38","author":"VN Pena","year":"2021","unstructured":"Pena VN et al (2021) Diagnostic and management strategies for patients with chronic prostatitis and chronic pelvic pain syndrome. Drugs Aging 38(10):845\u2013886","journal-title":"Drugs Aging"},{"issue":"1","key":"5575_CR9","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1186\/s13643-016-0384-4","volume":"5","author":"M Ouzzani","year":"2016","unstructured":"Ouzzani M et al (2016) Rayyan-a web and mobile app for systematic reviews. Syst Rev 5(1):210","journal-title":"Syst Rev"},{"issue":"5","key":"5575_CR10","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1016\/j.ypmed.2010.08.005","volume":"51","author":"MC Brouwers","year":"2010","unstructured":"Brouwers MC et al (2010) AGREE II: advancing guideline development, reporting, and evaluation in health care. Prev Med 51(5):421\u2013424","journal-title":"Prev Med"},{"key":"5575_CR11","unstructured":"Bailar, J.C. and F. Mosteller, Medical uses of statistics. 2nd ed. 1992, Boston, Mass.: NEJM Books. xxvii, 449 p."},{"key":"5575_CR12","unstructured":"Kirkwood, B.R. and J.A.C. Sterne, Essential medical statistics. 2nd ed. 2003, Malden, Mass.: Blackwell Science. x, 501 p."},{"issue":"7414","key":"5575_CR13","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","volume":"327","author":"JP Higgins","year":"2003","unstructured":"Higgins JP et al (2003) Measuring inconsistency in meta-analyses. BMJ 327(7414):557\u2013560","journal-title":"BMJ"},{"key":"5575_CR14","unstructured":"Hedges, L.V. and I. Olkin, Statistical methods for meta-analysis. 1985, Orlando: Academic Press. xxii, 369 p."},{"issue":"3","key":"5575_CR15","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","volume":"7","author":"R DerSimonian","year":"1986","unstructured":"DerSimonian R, Laird N (1986) Meta-analysis in clinical trials. Control Clin Trials 7(3):177\u2013188","journal-title":"Control Clin Trials"},{"key":"5575_CR16","unstructured":"F, S., MedCalc manual: Easy-to-use statistical software."},{"issue":"7109","key":"5575_CR17","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","volume":"315","author":"M Egger","year":"1997","unstructured":"Egger M et al (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315(7109):629\u2013634","journal-title":"BMJ"},{"issue":"10","key":"5575_CR18","doi-asserted-by":"publisher","first-page":"1046","DOI":"10.1016\/S0895-4356(01)00377-8","volume":"54","author":"JA Sterne","year":"2001","unstructured":"Sterne JA, Egger M (2001) Funnel plots for detecting bias in meta-analysis: guidelines on choice of axis. J Clin Epidemiol 54(10):1046\u20131055","journal-title":"J Clin Epidemiol"},{"key":"5575_CR19","doi-asserted-by":"publisher","first-page":"d4002","DOI":"10.1136\/bmj.d4002","volume":"343","author":"JA Sterne","year":"2011","unstructured":"Sterne JA et al (2011) Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials. BMJ 343:d4002","journal-title":"BMJ"},{"key":"5575_CR20","unstructured":"Borenstein, M., et al., Introduction to meta-analysis. Second edition. ed. 2021, Hoboken, NJ: John Wiley & Sons, Inc. xxxvi, 500 pages: illustrations."},{"issue":"7","key":"5575_CR21","doi-asserted-by":"publisher","first-page":"e010247","DOI":"10.1136\/bmjopen-2015-010247","volume":"6","author":"J IntHout","year":"2016","unstructured":"IntHout J et al (2016) Plea for routinely presenting prediction intervals in meta-analysis. BMJ Open 6(7):e010247","journal-title":"BMJ Open"},{"key":"5575_CR22","unstructured":"M, B., H. JPT, and R. HR. CMA Prediction Intervals. [accessed 1\/12\/2023]; Available from: https:\/\/www.meta-analysis.com\/pages\/prediction.php."},{"issue":"7748","key":"5575_CR23","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1038\/d41586-019-00857-9","volume":"567","author":"V Amrhein","year":"2019","unstructured":"Amrhein V, Greenland S, McShane B (2019) Scientists rise up against statistical significance. Nature 567(7748):305\u2013307","journal-title":"Nature"},{"issue":"9","key":"5575_CR24","doi-asserted-by":"publisher","first-page":"9870","DOI":"10.21037\/apm-21-2160","volume":"10","author":"W Deng","year":"2021","unstructured":"Deng W et al (2021) Systematic review and meta-analysis: \u03b1-adrenergic receptor blockers in chronic prostatitis. Ann Palliat Med 10(9):9870\u20139878","journal-title":"Ann Palliat Med"},{"issue":"4","key":"5575_CR25","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1111\/bju.14988","volume":"125","author":"JVA Franco","year":"2020","unstructured":"Franco JVA et al (2020) Pharmacological interventions for treating chronic prostatitis\/chronic pelvic pain syndrome: a Cochrane systematic review. BJU Int 125(4):490\u2013496","journal-title":"BJU Int"},{"issue":"1","key":"5575_CR26","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.juro.2006.08.090","volume":"177","author":"VC Mishra","year":"2007","unstructured":"Mishra VC, Browne J, Emberton M (2007) Role of alpha-blockers in type III prostatitis: a systematic review of the literature. J Urol 177(1):25\u201330","journal-title":"J Urol"},{"key":"5575_CR27","unstructured":"Le, B. and A.J. Schaeffer, 2011 Chronic prostatitis. BMJ Clin Evid 4:2011:1802"},{"issue":"8","key":"5575_CR28","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0041941","volume":"7","author":"JM Cohen","year":"2012","unstructured":"Cohen JM et al (2012) Therapeutic intervention for chronic prostatitis\/chronic pelvic pain syndrome (CP\/CPPS): a systematic review and meta-analysis. PLoS ONE 7(8):e41941","journal-title":"PLoS ONE"},{"issue":"7","key":"5575_CR29","doi-asserted-by":"publisher","first-page":"1014","DOI":"10.1111\/j.1464-410X.2012.11088.x","volume":"110","author":"A Thakkinstian","year":"2012","unstructured":"Thakkinstian A et al (2012) \u03b1-blockers, antibiotics and anti-inflammatories have a role in the management of chronic prostatitis\/chronic pelvic pain syndrome. BJU Int 110(7):1014\u20131022","journal-title":"BJU Int"},{"issue":"5","key":"5575_CR30","doi-asserted-by":"publisher","first-page":"367","DOI":"10.7326\/0003-4819-133-5-200009050-00013","volume":"133","author":"M McNaughton Collins","year":"2000","unstructured":"McNaughton Collins M, MacDonald R, Wilt TJ (2000) Diagnosis and treatment of chronic abacterial prostatitis: a systematic review. Ann Intern Med 133(5):367\u2013381","journal-title":"Ann Intern Med"},{"issue":"2","key":"5575_CR31","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1159\/000098064","volume":"78","author":"SW Lee","year":"2007","unstructured":"Lee SW et al (2007) Chronic prostatitis\/chronic pelvic pain syndrome: role of alpha blocker therapy. Urol Int 78(2):97\u2013105","journal-title":"Urol Int"},{"issue":"4","key":"5575_CR32","doi-asserted-by":"publisher","first-page":"e0280821","DOI":"10.1371\/journal.pone.0280821","volume":"18","author":"K Zhang","year":"2023","unstructured":"Zhang K et al (2023) Comparative analysis of efficacy of different combination therapies of \u03b1-receptor blockers and traditional Chinese medicine external therapy in the treatment of chronic prostatitis\/chronic pelvic pain syndrome: Bayesian network meta-analysis. PLoS ONE 18(4):e0280821","journal-title":"PLoS ONE"},{"issue":"5","key":"5575_CR33","doi-asserted-by":"publisher","first-page":"953","DOI":"10.1016\/j.eururo.2012.10.042","volume":"63","author":"FM Wagenlehner","year":"2013","unstructured":"Wagenlehner FM et al (2013) National institutes of health chronic prostatitis symptom index (NIH-CPSI) symptom evaluation in multinational cohorts of patients with chronic prostatitis\/chronic pelvic pain syndrome. Eur Urol 63(5):953\u2013959","journal-title":"Eur Urol"},{"issue":"10","key":"5575_CR34","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1111\/j.1525-1497.2001.01223.x","volume":"16","author":"M McNaughton Collins","year":"2001","unstructured":"McNaughton Collins M et al (2001) Quality of life is impaired in men with chronic prostatitis: the chronic prostatitis collaborative research network. J Gen Intern Med 16(10):656\u2013662","journal-title":"J Gen Intern Med"}],"container-title":["World Journal of Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00345-025-05575-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00345-025-05575-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00345-025-05575-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T13:50:48Z","timestamp":1767966648000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00345-025-05575-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,1]]},"references-count":34,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["5575"],"URL":"https:\/\/doi.org\/10.1007\/s00345-025-05575-8","relation":{},"ISSN":["1433-8726"],"issn-type":[{"value":"1433-8726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,1]]},"assertion":[{"value":"2 January 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 March 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 April 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"204"}}