{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T22:54:02Z","timestamp":1791327242080,"version":"4.3.1"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T00:00:00Z","timestamp":1752710400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T00:00:00Z","timestamp":1752710400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100002352","name":"Ain Shams University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002352","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World J Urol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the safety and efficacy of Rez\u016bm therapy in small versus large prostates through a four-year follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>One-hundred seventy patients who underwent Rez\u016bm therapy were retrospectively included and divided into 2 equal groups, small (\u02c2 80gm) and large prostate groups (80-120 gm). Both groups were assessed preoperatively and at 3, 12, 24, 36, and 48 months post-procedure for operative time, number of vapor injection, catheterization time, hospital stay and post-procedure: prostatic size, prostate-specific antigen (PSA), post-void residual (PVR), maximum urinary flow rate (Qmax), International Prostate Symptom Score (IPSS), quality of life (QoL), International Index of Erectile Function (IIEF) and complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The number of vapor injections was significantly higher in the large prostate group compared to the small prostate group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Operative time and catheter duration were significantly longer in the large prostate group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), while hospital stay was similar between groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.407). At 48 months post-Rez\u016bm, both groups demonstrated statistically significant improvement in all measured outcomes (Qmax, IPSS, PVR, QoL, PSA, IIEF, and prostate size) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Regarding postoperative complications, there were no significant differences between the groups except that the need for retreatment was significantly higher in the large prostate group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Rez\u016bm therapy offers a safe and effective treatment option for both small and large prostates with sustained improvement over four years. However, patients with large prostates exhibited a higher retreatment rate (15.2%).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00345-025-05793-0","type":"journal-article","created":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T17:49:06Z","timestamp":1752774546000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["A comparative analysis of the outcomes of Rez\u016bm therapy based on prostate size: a four-year retrospective analysis"],"prefix":"10.1007","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0162-079X","authenticated-orcid":false,"given":"Mohamed","family":"Samir","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud Ahmed","family":"Mahmoud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hossam Abdelsamie","family":"Abdelmonem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Elrefaie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled Abdelsattar","family":"Gad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,7,17]]},"reference":[{"issue":"1","key":"5793_CR1","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/j.urology.2008.03.015","volume":"72","author":"E -Suer","year":"2008","unstructured":"-Suer E, Gokce I, Yaman O, Anafarta K, Gogus O (2008) Open prostatectomy is still a valid option for large prostates: a high-volume, single-center experience. 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