{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T22:07:39Z","timestamp":1783462059657,"version":"3.55.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:00Z","timestamp":1782172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:00Z","timestamp":1782172800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100016981","name":"Necmettin Erbakan University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100016981","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World J Urol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Routine ureteral stenting after flexible ureterorenoscopy (F-URS) remains controversial. While stents are used to secure drainage, their impact on subclinical renal tubular injury is not well defined. This study aimed to evaluate the effect of postoperative Double-J (DJ) stenting on acute and subacute renal injury using urinary Kidney Injury Molecule-1 (KIM-1) as a sensitive biomarker.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective analysis of a prospectively maintained database including 117 patients who underwent F-URS for renal stones. To minimize selection bias, patients with severe ureteral injury (PULS Grade\u2009\u2265\u20093) were excluded, and a ureteral access sheath (UAS) was utilized in all cases to standardize intrarenal pressure. Patients were stratified into two groups according to the postoperative drainage strategy: Group 1 (DJ stent) and Group 2 (no stent). Urinary KIM-1 levels normalized to creatinine (KIM-1\/Cr) were measured preoperatively, at the postoperative 4th hour (acute phase), and on day 14 (subacute phase).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Demographic characteristics and operative trauma scores (PULS) were comparable between the groups. In the acute phase (4th hour), both groups exhibited a significant and similar rise in KIM-1\/Cr levels compared to baseline (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), with no intergroup difference (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.748). However, in the subacute phase (day 14), the stented group had significantly lower KIM-1\/Cr levels compared to the non-stented group (0.18 vs. 0.36;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). Additionally, the stone-free rate (SFR) was significantly higher in the stented group (89.8% vs. 65.5%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002). Postoperative complication rates were similar (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.35).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>DJ stent placement does not alter the acute biomarker surge associated with surgical stress but is associated with significantly lower KIM-1\/Cr levels during the subacute recovery period. This finding suggests that improved drainage, together with more effective stone clearance, may contribute to better tubular recovery in stented patients. Urinary KIM-1 serves as a valuable objective tool for monitoring subclinical renal injury and may guide individualized stenting decisions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00345-026-06552-5","type":"journal-article","created":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T11:55:16Z","timestamp":1782215716000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of DJ stenting on subacute renal recovery after flexible ureterorenoscopy"],"prefix":"10.1007","volume":"44","author":[{"given":"G\u00f6khan","family":"Ecer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selim","family":"Soyt\u00fcrk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eren","family":"Erol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah","family":"Altunhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haider Nihad Izaddin","family":"Alalam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5009-8435","authenticated-orcid":false,"given":"Sel\u00e7uk","family":"G\u00fcven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet","family":"Balasar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,23]]},"reference":[{"issue":"3","key":"6552_CR1","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1016\/j.eururo.2015.07.041","volume":"69","author":"C T\u00fcrk","year":"2016","unstructured":"T\u00fcrk C, Pet\u0159\u00edk A, Sarica K, Seitz C, Skolarikos A, Straub M et al (2016) EAU guidelines on interventional treatment for urolithiasis. 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