{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T04:55:09Z","timestamp":1761540909860},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2009,2,27]],"date-time":"2009-02-27T00:00:00Z","timestamp":1235692800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmologe"],"published-print":{"date-parts":[[2009,3]]},"DOI":"10.1007\/s00347-008-1908-7","type":"journal-article","created":{"date-parts":[[2009,2,25]],"date-time":"2009-02-25T06:53:55Z","timestamp":1235544835000},"page":"235-241","source":"Crossref","is-referenced-by-count":13,"title":["Das \u201efeuchte\u201c trockene Auge"],"prefix":"10.1007","volume":"106","author":[{"given":"M.","family":"Schargus","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Geerling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,2,27]]},"reference":[{"key":"1908_CR1","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S1542-0124(12)70081-2","volume":"5","author":"Anonymous","year":"2007","unstructured":"Anonymous (2007) The definition and classification of dry eye disease: report of the Definition and Classification Subcommittee of the International Dry Eye WorkShop (2007). Ocul Surf 5:75\u201392","journal-title":"Ocul Surf"},{"key":"1908_CR2","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1136\/bjo.2006.091579","volume":"90","author":"Aronowicz","year":"2006","unstructured":"Aronowicz JD, Shine WE, Oral D et al (2006) Short term oral minocycline treatment of meibomianitis. Br J Ophthalmol 90:856\u2013860","journal-title":"Br J Ophthalmol"},{"key":"1908_CR3","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/S0002-9394(03)00326-X","volume":"136","author":"Avunduk","year":"2003","unstructured":"Avunduk AM, Avunduk MC, Varnell ED et al (2003) The comparison of efficacies of topical corticosteroids and nonsteroidal anti-inflammatory drops on dry eye patients: a clinical and immunocytochemical study. Am J Ophthalmol 136:593\u2013602","journal-title":"Am J Ophthalmol"},{"key":"1908_CR4","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1097\/00003226-200303000-00002","volume":"22","author":"Barabino","year":"2003","unstructured":"Barabino S, Rolando M, Camicione P et al (2003) Systemic linoleic and gamma-linolenic acid therapy in dry eye syndrome with an inflammatory component. Cornea 22:97\u2013101","journal-title":"Cornea"},{"key":"1908_CR5","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1097\/00006324-200001000-00012","volume":"77","author":"Begley","year":"2000","unstructured":"Begley CG, Caffery B, Nichols KK et al (2000) Responses of contact lens wearers to a dry eye survey. Optom Vis Sci 77:40\u201346","journal-title":"Optom Vis Sci"},{"key":"1908_CR6","first-page":"90","volume":"42","author":"Brignole","year":"2001","unstructured":"Brignole F, Pisella PJ, De Saint JM et al (2001) Flow cytometric analysis of inflammatory markers in KCS: 6-month treatment with topical cyclosporin A. Invest Ophthalmol Vis Sci 42:90\u201395","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1908_CR7","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S1542-0124(12)70150-7","volume":"2","author":"Bron","year":"2004","unstructured":"Bron AJ, Tiffany JM (2004) The contribution of meibomian disease to dry eye. Ocul Surf 2:149\u2013165","journal-title":"Ocul Surf"},{"key":"1908_CR8","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/j.exer.2006.02.004","volume":"83","author":"De","year":"2006","unstructured":"De Paiva CS, Corrales RM, Villarreal AL et al (2006) Corticosteroid and doxycycline suppress MMP-9 and inflammatory cytokine expression, MAPK activation in the corneal epithelium in experimental dry eye. Exp Eye Res 83:526\u2013535","journal-title":"Exp Eye Res"},{"key":"1908_CR9","first-page":"486","volume":"27","author":"Dougherty","year":"1986","unstructured":"Dougherty JM, Mcculley JP (1986) Bacterial lipases and chronic blepharitis. Invest Ophthalmol Vis Sci 27:486\u2013491","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1908_CR10","first-page":"2970","volume":"32","author":"Dougherty","year":"1991","unstructured":"Dougherty JM, Mcculley JP, Silvany RE et al (1991) The role of tetracycline in chronic blepharitis. Inhibition of lipase production in staphylococci. Invest Ophthalmol Vis Sci 32:2970\u20132975","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1908_CR11","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1097\/00006324-199708000-00023","volume":"74","author":"Doughty","year":"1997","unstructured":"Doughty MJ, Fonn D, Richter D et al (1997) A patient questionnaire approach to estimating the prevalence of dry eye symptoms in patients presenting to optometric practices across Canada. Optom Vis Sci 74:624\u2013631","journal-title":"Optom Vis Sci"},{"key":"1908_CR12","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S1542-0124(12)70139-8","volume":"1","author":"Foulks","year":"2003","unstructured":"Foulks GN, Bron AJ (2003) Meibomian gland dysfunction: a clinical scheme for description, diagnosis, classification and grading. Ocul Surf 1:107\u2013126","journal-title":"Ocul Surf"},{"key":"1908_CR13","first-page":"948","volume":"42","author":"Geerling","year":"2001","unstructured":"Geerling G, Daniels JT, Dart JK et al (2001) Toxicity of natural tear substitutes in a fully defined culture model of human corneal epithelial cells. Invest Ophthalmol Vis Sci 42:948\u2013956","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1908_CR14","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1212\/WNL.34.5.677","volume":"34","author":"Karson","year":"1984","unstructured":"Karson CN, Burns RS, Lewitt PA et al (1984) Blink rates and disorders of movement. Neurology 34:677\u2013678","journal-title":"Neurology"},{"key":"1908_CR15","first-page":"2483","volume":"42","author":"Kunert","year":"2001","unstructured":"Kunert KS, Keane-Myers AM, Spurr-Michaud S et al (2001) Alteration in goblet cell numbers and mucin gene expression in a mouse model of allergic conjunctivitis. Invest Ophthalmol Vis Sci 42:2483\u20132489","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1908_CR16","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/0091-3057(91)90255-Z","volume":"38","author":"Lawrence","year":"1991","unstructured":"Lawrence MS, Redmond DE Jr (1991) MPTP lesions and dopaminergic drugs alter eye blink rate in African green monkeys. Pharmacol Biochem Behav 38:869\u2013874","journal-title":"Pharmacol Biochem Behav"},{"key":"1908_CR17","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1097\/00003226-199107000-00002","volume":"10","author":"Mathers","year":"1991","unstructured":"Mathers WD, Shields WJ, Sachdev MS et al (1991) Meibomian gland morphology and tear osmolarity: changes with Accutane therapy. Cornea 10:286\u2013290","journal-title":"Cornea"},{"key":"1908_CR18","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/S0002-9394(14)71639-3","volume":"124","author":"Nakamori","year":"1997","unstructured":"Nakamori K, Odawara M, Nakajima T et al (1997) Blinking is controlled primarily by ocular surface conditions. Am J Ophthalmol 124:24\u201330","journal-title":"Am J Ophthalmol"},{"key":"1908_CR19","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1167\/iovs.05-1392","volume":"47","author":"Nichols","year":"2006","unstructured":"Nichols JJ, Sinnott LT (2006) Tear film, contact lens and patient-related factors associated with contact lens-related dry eye. Invest Ophthalmol Vis Sci 47:1319\u20131328","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1908_CR20","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.ajo.2003.10.036","volume":"137","author":"Pflugfelder","year":"2004","unstructured":"Pflugfelder SC (2004) Antiinflammatory therapy for dry eye. Am J Ophthalmol 137:337\u2013342","journal-title":"Am J Ophthalmol"},{"key":"1908_CR21","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1177\/112067210201200505","volume":"12","author":"Pharmakakis","year":"2002","unstructured":"Pharmakakis NM, Katsimpris JM, Melachrinou MP et al (2002) Corneal complications following abuse of topical anesthetics. Eur J Ophthalmol 12:373\u2013378","journal-title":"Eur J Ophthalmol"},{"key":"1908_CR22","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1136\/bjo.86.4.418","volume":"86","author":"Pisella","year":"2002","unstructured":"Pisella PJ, Pouliquen P, Baudouin C (2002) Prevalence of ocular symptoms and signs with preserved and preservative free glaucoma medication. Br J Ophthalmol 86:418\u2013423","journal-title":"Br J Ophthalmol"},{"key":"1908_CR23","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.exer.2004.07.007","volume":"79","author":"Qian","year":"2004","unstructured":"Qian L, Xie J, Rose CM et al (2004) Altered traffic to the lysosome in an ex vivo lacrimal acinar cell model for chronic muscarinic receptor stimulation. Exp Eye Res 79:665\u2013675","journal-title":"Exp Eye Res"},{"key":"1908_CR24","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1159\/000309511","volume":"190","author":"Rolando","year":"1985","unstructured":"Rolando M, Refojo MF, Kenyon KR (1985) Tear water evaporation and eye surface diseases. Ophthalmologica 190:147\u2013149","journal-title":"Ophthalmologica"},{"key":"1908_CR25","first-page":"2272","volume":"32","author":"Shine","year":"1991","unstructured":"Shine WE, Mcculley JP (1991) The role of cholesterol in chronic blepharitis. Invest Ophthalmol Vis Sci 32:2272\u20132280","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1908_CR26","first-page":"2291","volume":"34","author":"Shine","year":"1993","unstructured":"Shine WE, Silvany R, Mcculley JP (1993) Relation of cholesterol-stimulated Staphylococcus aureus growth to chronic blepharitis. Invest Ophthalmol Vis Sci 34:2291\u20132296","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1908_CR27","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/0002-9394(82)90703-6","volume":"93","author":"Sommer","year":"1982","unstructured":"Sommer A, Emran N (1982) Tear production in vitamin A-responsive xerophthalmia. Am J Ophthalmol 93:84\u201387","journal-title":"Am J Ophthalmol"},{"key":"1908_CR28","first-page":"672","volume":"51","author":"Tamargo","year":"1991","unstructured":"Tamargo RJ, Bok RA, Brem H (1991) Angiogenesis inhibition by minocycline. Cancer Res 51:672\u2013675","journal-title":"Cancer Res"},{"key":"1908_CR29","first-page":"709","volume":"41","author":"Tang","year":"2000","unstructured":"Tang NE, Zuure PL, Pardo RD et al (2000) Reflex lacrimation in patients with glaucoma and healthy control subjects by fluorophotometry. Invest Ophthalmol Vis Sci 41:709\u2013714","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1908_CR30","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1097\/00003226-200007000-00018","volume":"19","author":"Turner","year":"2000","unstructured":"Turner K, Pflugfelder SC, Ji Z et al (2000) Interleukin-6 levels in the conjunctival epithelium of patients with dry eye disease treated with cyclosporine ophthalmic emulsion. Cornea 19:492\u2013496","journal-title":"Cornea"}],"container-title":["Der Ophthalmologe"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00347-008-1908-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00347-008-1908-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00347-008-1908-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T09:50:55Z","timestamp":1559037055000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00347-008-1908-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2,27]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,3]]}},"alternative-id":["1908"],"URL":"https:\/\/doi.org\/10.1007\/s00347-008-1908-7","relation":{},"ISSN":["0941-293X","1433-0423"],"issn-type":[{"value":"0941-293X","type":"print"},{"value":"1433-0423","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,2,27]]}}}