{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T23:49:20Z","timestamp":1792280960271,"version":"4.4.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2013,6,1]],"date-time":"2013-06-01T00:00:00Z","timestamp":1370044800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/2.0"},{"start":{"date-parts":[[2013,6,13]],"date-time":"2013-06-13T00:00:00Z","timestamp":1371081600000},"content-version":"vor","delay-in-days":12,"URL":"https:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ophthalmologe"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n          <jats:p>Die bisherige Therapiepraxis, Kontaktlinsentr\u00e4ger mit Sicca-Beschwerden einseitig mit Hyalurons\u00e4ure-Tr\u00e4nenersatzmitteln zu behandeln, ist fragw\u00fcrdig. Bei Kontaktlinsentr\u00e4gern mit Beschwerden des trockenen Auges liegt mehrheitlich eine gest\u00f6rte Meibom-Dr\u00fcsen-Funktion vor, die eine Verminderung der Lipidphase des Tr\u00e4nenfilms zur Folge hat. Die damit assoziierte erheblich erh\u00f6hte Verdunstung der w\u00e4ssrigen Tr\u00e4nenfilmteile bedingt die messbare Hyperosmolarit\u00e4t des zur\u00fcckbleibenden \u201a\u201adenaturierten\u2019\u2018 Tr\u00e4nenfilms. Eine konsekutive inflammatorische Reaktion der Augenoberfl\u00e4che kann dann zum bekannten Circulus vitiosus des trockenen Auges f\u00fchren. Um der Dehydrierung durch das Kontaktlinsenmaterial vorzubeugen, sind phosphatfreie, unkonservierte w\u00e4ssrige Tr\u00e4nenersatzmittel sinnvoll. Wird eine verk\u00fcrzte Tr\u00e4nenfilmaufrisszeit festgestellt, so ist bei der Therapie die Supplementierung der Lipide (z.\u00a0B. mit Phospholipid-Augenspray) erforderlich. Im Falle einer assoziierten Blepharitis ist die zus\u00e4tzliche regelm\u00e4\u00dfige Lidrandhygiene mit einer phospholiposomalen Reinigungsl\u00f6sung therapeutisch sinnvoll und der Lidrandreinigung mit Babyshampoo \u00fcberlegen.<\/jats:p>","DOI":"10.1007\/s00347-013-2864-4","type":"journal-article","created":{"date-parts":[[2013,6,19]],"date-time":"2013-06-19T16:04:01Z","timestamp":1371657841000},"page":"511-514","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Trockenes Auge bei Kontaktlinsentr\u00e4gern","Contact lens associated dry eye"],"prefix":"10.1007","volume":"110","author":[{"given":"R.","family":"Khaireddin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,6,13]]},"reference":[{"key":"2864_CR1","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/S1542-0124(12)70081-2","volume":"5","author":"Anonymous","year":"2007","unstructured":"Anonymous (2007) The definition and classification of dry eye disease: report of the Definition and Classification Subcommittee of the International Dry Eye WorkShop (2007). 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