{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T03:21:58Z","timestamp":1740108118561,"version":"3.37.3"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2020,8,7]],"date-time":"2020-08-07T00:00:00Z","timestamp":1596758400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,8,7]],"date-time":"2020-08-07T00:00:00Z","timestamp":1596758400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005690","name":"Universit\u00e4t des Saarlandes","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005690","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ophthalmologe"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:sec>\n                <jats:title>Hintergrund und Zielsetzung<\/jats:title>\n                <jats:p>Torische Kapselsacklinsen bieten heutzutage eine zuverl\u00e4ssige Option der permanenten Korrektur eines Hornhautastigmatismus. Zur Ermittlung der f\u00fcr den gew\u00fcnschten Ausgleich erforderlichen Linsenst\u00e4rke kann der Operateur entweder auf die in seinem Biometrieger\u00e4t implementierten Berechnungsmodi oder auf den vom Linsenhersteller angebotenen Kalkulationsservice zur\u00fcckgreifen. In vielen F\u00e4llen wird dabei allerdings keine klassische Linsenberechnung aus biometrischen Daten durchgef\u00fchrt, sondern nur mit einer vereinfachten Absch\u00e4tzung gearbeitet, die den Hornhautastigmatismus in den Torus der tIOL \u00fcbersetzt. Dieses dann zumeist als durchschnittlicher Standardwert genutzte \u00dcbersetzungsverh\u00e4ltnis kann jedoch eine erhebliche Schwankungsbreite aufweisen, sodass im ung\u00fcnstigsten Fall eine Unterkorrektur des refraktiven Zylinders um bis zu 12,5\u202f% oder eine \u00dcberkorrektur um bis zu 17\u202f% resultieren kann. Ziel dieser Studie war es aufzuzeigen, welche biometrischen Einflussgr\u00f6\u00dfen das Verh\u00e4ltnis zwischen dem zu korrigierenden Hornhautastigmatismus und dem f\u00fcr dessen Vollkorrektur notwendigen Torus einer Kapselsacklinse bestimmen.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methoden<\/jats:title>\n                <jats:p>Aus der WEB-Plattform IOLCon wurden 16.744 Datens\u00e4tze extrahiert, und anhand der pr\u00e4operativen biometrischen Gr\u00f6\u00dfen und dem postoperativen sph\u00e4rischen \u00c4quivalent wurde zun\u00e4chst die axiale Position der Kapselsacklinse formelunabh\u00e4ngig abgeleitet. Anschlie\u00dfend wurde, basierend auf der Propagation sph\u00e4rozylindrischer Vergenzen, der entsprechende Brechwert einer emmetropisierenden Kapselsacklinse ermittelt. Das \u00dcbersetzungsverh\u00e4ltnis als Quotient aus dem Torus der Linse und dem Hornhautastigmatismus wurde mit einer Monte-Carlo-Simulation auf seine potenziellen Einflussgr\u00f6\u00dfen hin untersucht.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Ergebnisse<\/jats:title>\n                <jats:p>Die Monte-Carlo-Simulation zeigt, dass nicht von einem konstanten \u00dcbersetzungsverh\u00e4ltnis ausgegangen werden kann. F\u00fcr die hier zugrunde gelegten klinischen F\u00e4lle ergibt sich ein mittleres \u00dcbersetzungsverh\u00e4ltnis von 1,3938\u202f\u00b1\u20090,0595 (Median 1,3921) mit einer Spannweite von 1,2131 bis 1,5974. Den gr\u00f6\u00dften Einfluss hat hierbei die axiale Position der Kapselsacklinse \u2013 je weiter posterior sich diese befindet, desto h\u00f6her ist das \u00dcbersetzungsverh\u00e4ltnis. Aufgrund der Korrelation der axialen Linsenposition mit der Augenl\u00e4nge kann die Augenl\u00e4nge als indirekte Einflussgr\u00f6\u00dfe gewertet werden. Der \u00c4quivalentbrechwert sowie der Astigmatismus der Hornhaut besitzen keinen nennenswerten Effekt auf das \u00dcbersetzungsverh\u00e4ltnis.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Diskussion<\/jats:title>\n                <jats:p>In einer ganzen Reihe von Berechnungsmodulen wird die Kalkulation des Torus der Kapselsacklinse dahingehend vereinfacht, dass dieser mittels eines einfachen konstanten Umrechnungsfaktors aus dem gemessenen Hornhautastigmatismus abgeleitet wird. Die vorliegende Studie zeigt jedoch, dass diese Vereinfachung zu deutlich fehlerhaften Ergebnissen f\u00fchren kann. Dementsprechend wird eine individuelle Berechnung des Torus der IOL aus gemessenen biometrischen Gr\u00f6\u00dfen (z.\u202fB. mittels Vergenzpropagation, Matrizen oder mittels Full-aperture<jats:bold>-<\/jats:bold>Raytracing) empfohlen.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00347-020-01199-y","type":"journal-article","created":{"date-parts":[[2020,8,7]],"date-time":"2020-08-07T12:02:58Z","timestamp":1596801778000},"page":"569-577","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Monte-Carlo-Simulation biometrischer Effektgr\u00f6\u00dfen und deren Einfluss auf das \u00dcbersetzungsverh\u00e4ltnis des Hornhautastigmatismus in den Zylinder torischer Intraokularlinsen","Monte Carlo simulation of biometric effect sizes and their influence on the translational ratio of corneal astigmatism in the cylinders of toric intraocular lenses"],"prefix":"10.1007","volume":"118","author":[{"given":"Achim","family":"Langenbucher","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Schrecker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Schwemm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timo","family":"Eppig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Schr\u00f6der","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N\u00f3ra","family":"Szentm\u00e1ry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,8,7]]},"reference":[{"issue":"5","key":"1199_CR1","doi-asserted-by":"publisher","first-page":"936","DOI":"10.1016\/j.jcrs.2014.08.036","volume":"41","author":"A Abulafia","year":"2015","unstructured":"Abulafia\u00a0A, Barrett\u00a0GD, Kleinmann\u00a0G, Ofir\u00a0S, Levy\u00a0A, Marcovich\u00a0AL, Michaeli\u00a0A, Koch\u00a0DD, Wang\u00a0L, Assia\u00a0EI (2015) Prediction of refractive outcomes with toric intraocular lens implantation. 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