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Ziel dieser Arbeit ist es, den Einfluss der Dezentrierung und Verkippung auf die Induktion von Defokus, Astigmatismus und Coma im phaken und pseudophaken Auge zu untersuchen.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methoden<\/jats:title><jats:p>Auf der Basis des Liou-Brennan-Modellauges wurde eine Simulation mit Zemax durchgef\u00fchrt. Ausgehend von der im Augenmodell beschriebenen Position der Gradientenlinse, wurde nach der Bestimmung der Fokusebene die Linse von \u22121,0 bis 1,0\u202fmm in Schritten von 0,2\u202fmm horizontal dezentriert und von \u221210\u00b0 bis 10\u00b0 in Schritten von 2\u00b0 um die vertikale Achse verkippt. Zu jeder der 121 Kombinationen wurde bei einer Pupille von 4\u202fmm der Defokus, der regul\u00e4re Astigmatismus in 0\/180\u00b0 sowie die horizontale Coma aus der Wellenfront extrahiert. Analog zum phaken Auge wurde die Gradientenlinse durch ein aberrationskorrigierendes Kunstlinsenmodell ersetzt und die Simulation f\u00fcr das pseudophake Auge wiederholt.<\/jats:p><\/jats:sec><jats:sec><jats:title>Ergebnisse<\/jats:title><jats:p>Ist die Linse im phaken\/pseudophaken Auge entsprechend den Vorgaben des Liou-Brennan-Modellauges positioniert, ergibt die Simulation einen Defokus von 0,026\/\u22120,001\u202fdpt, einen Astigmatismus von \u22120,045\/\u22120,018\u202fdpt sowie eine Coma von \u22120,015\/0,047\u202f\u00b5m. Maximale Werte treten bei einer Dezentrierung von 1,0\u202fmm und einer Verkippung von 10\u00b0 auf: 1,547\/2,982\u202fdpt f\u00fcr den Defokus, 0,971\/1,871\u202fdpt f\u00fcr den Astigmatismus sowie 0,441\/1,209\u202f\u00b5m f\u00fcr die Coma. Maximal negative Werte treten im phaken\/pseudophaken Auge auf bei: \u22120,293\/\u22121,224\u202fdpt f\u00fcr den Defokus, \u22120,625\/\u22120,663\u202fdpt f\u00fcr den Astigmatismus sowie \u22120,491\/\u22120,559\u202f\u00b5m f\u00fcr die Coma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Diskussion<\/jats:title><jats:p>In dieser Studie wurde erstmals der Effekt einer Kombination aus horizontaler Dezentrierung der Linse und Verkippung um die Vertikale auf den induzierten Defokus, Astigmatismus sowie die horizontale Coma in einem Simulationsmodell untersucht. Die Ergebnisse k\u00f6nnen bei der Ursachenforschung helfen, wenn bei dezentrierter oder verkippter Kunstlinse die Zielrefraktion nicht mit der erreichten Refraktion \u00fcbereinstimmt oder der resultierende Astigmatismus durch den Hornhautastigmatismus alleine nicht erkl\u00e4rbar ist.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00347-020-01235-x","type":"journal-article","created":{"date-parts":[[2020,9,30]],"date-time":"2020-09-30T14:03:41Z","timestamp":1601474621000},"page":"828-837","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Kombination aus Dezentrierung und Verkippung der Linse im phaken und pseudophaken Auge \u2013 optische Simulation von Defokus, Astigmatismus und Coma","Combination of lens decentration and tilt in phakic and pseudophakic eyes\u2014Optical simulation of defocus, astigmatism and coma"],"prefix":"10.1007","volume":"118","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9175-6177","authenticated-orcid":false,"given":"Achim","family":"Langenbucher","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pooria","family":"Omidi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timo","family":"Eppig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N\u00f3ra","family":"Szentm\u00e1ry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rupert","family":"Menapace","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Hoffmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,9,30]]},"reference":[{"issue":"13","key":"1235_CR1","doi-asserted-by":"publisher","first-page":"5263","DOI":"10.1167\/iovs.16-20067","volume":"57","author":"DA Atchison","year":"2016","unstructured":"Atchison\u00a0DA, Suheimat\u00a0M, Mathur\u00a0A, Lister\u00a0LJ, Rozema\u00a0J (2016) Anterior corneal, posterior corneal, and lenticular contributions to ocular aberrations. 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F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}