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Die Beobachtbarkeit von Ver\u00e4nderungen der retinalen Gef\u00e4\u00dfe im Zusammenhang mit KVE mittels Fundoskopie ist schon seit Langem bekannt. Ein neuartiges Verfahren zur nichtinvasiven und detaillierten Darstellung und Quantifizierung der retinalen und papill\u00e4ren Gef\u00e4\u00dfe stellt die optische Koh\u00e4renztomographie-Angiographie (OCT-A) dar. Durch die OCT\u2011A ist es m\u00f6glich, Gef\u00e4\u00dfver\u00e4nderungen einfach und gut reproduzierbar zu visualisieren, weswegen ihr Einsatz nicht nur auf augen\u00e4rztliche Fragestellungen beschr\u00e4nkt ist. In den vergangenen Jahren sind einige experimentelle und klinische Studien zur Darstellbarkeit und Quantifizierung von Gef\u00e4\u00dfver\u00e4nderungen durch die OCT\u2011A bei Erkrankungen des kardiovaskul\u00e4ren Spektrums publiziert worden. In der vorliegenden \u00dcbersicht werden die wichtigsten Erkenntnisse aus diesen Studien zusammengefasst.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methoden<\/jats:title>\n                <jats:p>Grundlage dieser Arbeit bilden eine umfassende selektive Literaturrecherche und die Darstellung eigener Daten.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Ergebnisse<\/jats:title>\n                <jats:p>Mittlerweile liegen zu vielen Erkrankungen des kardiovaskul\u00e4ren Spektrums OCT-A-Studien vor, die verdeutlichen, dass systemische Gef\u00e4\u00dferkrankungen mit Ver\u00e4nderungen der retinalen Mikrozirkulation verbunden sind. Mit der OCT\u2011A k\u00f6nnen diese Ver\u00e4nderungen visualisiert und reproduzierbar quantifiziert werden. Oftmals ist es m\u00f6glich, subklinische Ver\u00e4nderungen aufzuzeigen, bevor die zugrunde liegende Erkrankung anderweitig messbare Ver\u00e4nderungen oder f\u00fcr den Patienten merkbare Symptome verursacht.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Schlussfolgerung<\/jats:title>\n                <jats:p>Die OCT\u2011A ist eine vielversprechende Bildgebungsmethode auf dem Gebiet der KVE in Wissenschaft und klinischer Anwendung. Sie kann zur Diagnostik und Quantifizierung retinaler Gef\u00e4\u00dfver\u00e4nderungen eingesetzt werden. Weitere Studien werden zeigen, ob die OCT\u2011A bei der Einsch\u00e4tzung des individuellen kardiovaskul\u00e4ren Risikoprofils helfen kann.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00347-021-01336-1","type":"journal-article","created":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T14:11:33Z","timestamp":1614003093000},"page":"1119-1127","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Die optische Koh\u00e4renztomographie-Angiographie und Erkrankungen des kardiovaskul\u00e4ren Spektrums. Ein \u00dcberblick \u00fcber die aktuelle Studienlage","Optical coherence tomography angiography and cardiovascular diseases. 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