{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T12:32:01Z","timestamp":1789561921750,"version":"build-2803163510"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T00:00:00Z","timestamp":1616976000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T00:00:00Z","timestamp":1616976000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e4tsklinikum W\u00fcrzburg"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ophthalmologe"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:sec>\n                <jats:title>Ziel<\/jats:title>\n                <jats:p>Ziel dieser Studie war es, die 2\u2011Jahres-Ergebnisse der filtrierenden Trabekulotomie (FTO) im Vergleich zur konventionellen Trabekulektomie (TE) bei prim\u00e4rem Offenwinkelglaukom, Pseudoexfoliationsglaukom und Pigmentglaukom zu untersuchen.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Patienten und Methoden<\/jats:title>\n                <jats:p>Es wurden 30 konsekutive Patienten nach FTO und 87\u00a0Patienten nach TE nach intraokularem Druck (IOD) und Alter im Verh\u00e4ltnis\u00a01:3 gematcht. Prim\u00e4rer Endpunkt war das Erreichen des Zieldrucks nach 2\u00a0Jahren. Als vollst\u00e4ndiger Erfolg wurde ein IOD ohne Medikamente von \u2264\u202f18\u202fmm\u202fHg bei gleichzeitiger IOD-Reduktion um \u2265\u202f30\u202f% definiert, als qualifizierter Erfolg, wenn hierf\u00fcr zus\u00e4tzlich Medikamente erforderlich waren. Sekund\u00e4re Endpunkte waren mittlere Drucksenkung, resultierende Sehsch\u00e4rfe, Komplikationen und nachfolgende Operationen. Die Operationstechnik der filtrierenden Trabekulotomie ist als Video zu diesem Beitrag abrufbar.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Ergebnisse<\/jats:title>\n                <jats:p>Zwei-Jahres-Daten konnten von 27\u00a0Patienten aus der FTO-Gruppe und 68\u00a0Patienten aus der TE-Gruppe erhoben werden. Die Patienten beider Gruppen wurden vor Beginn der Studie bez\u00fcglich Alter und IOD gematcht, waren aber auch bez\u00fcglich Sehsch\u00e4rfe, Geschlecht und Medikation nicht unterschiedlich. Der Median des pr\u00e4operativen IOD unter Therapie betrug in beiden Gruppen 23,0\u202fmm\u202fHg. Nach den oben genannten Kriterien wurde ein qualifizierter 2\u2011Jahres-Erfolg bei 70,4\u202f% der FTO-Gruppe und bei 77,6\u202f% der TE-Gruppe erzielt (<jats:italic>p<\/jats:italic>\u202f=\u20090,60), ein vollst\u00e4ndiger 2\u2011Jahres-Erfolg bei 33,3\u202f% der FTO-Gruppe und bei 56,7\u202f% der TE-Gruppe (<jats:italic>p<\/jats:italic>\u202f=\u20090,07). Beide Operationsmethoden senkten den Augeninnendruck nach 24\u00a0Monaten signifikant (<jats:italic>p<\/jats:italic>\u202f&lt;\u202f0,001), und zwar auf 12,8\u202fmm\u202fHg in der FTO-Gruppe und 11,0\u202fmm\u202fHg in der TE-Gruppe. Die Sehsch\u00e4rfe war postoperativ bei beiden Gruppen etwas verringert, unterschied sich jedoch nicht signifikant zwischen beiden Gruppen. Komplikations- und Reoperationsrate waren gering und unterschieden sich nicht zwischen den Gruppen.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Schlussfolgerung<\/jats:title>\n                <jats:p>FTO und TE sind nach 2\u00a0Jahren weitgehend gleichwertig bez\u00fcglich Zieldruck, IOD-Senkung, Sehsch\u00e4rfe und Komplikationen.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00347-021-01365-w","type":"journal-article","created":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T15:02:55Z","timestamp":1617030175000},"page":"461-469","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Ergebnisse der filtrierenden Trabekulotomie (FTO) im Vergleich zur konventionellen Trabekulektomie (TE)\u00a0\u2013 eine gematchte Fall-Kontroll-Studie","Results of filtering trabeculotomy (FTO) compared to conventional trabeculectomy (TE)\u2014a\u00a0matched case control study"],"prefix":"10.1007","volume":"118","author":[{"given":"Caroline Maria","family":"Glatzel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1gnes","family":"Patzk\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliane","family":"Matlach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franz","family":"Grehn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,3,29]]},"reference":[{"key":"1365_CR1","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1136\/bjophthalmol-2018-313396","volume":"104","author":"GS Ang","year":"2020","unstructured":"Ang\u00a0GS, Fenwick\u00a0EK, Constantinou\u00a0M et\u00a0al (2020) Selective laser trabeculoplasty versus topical medication as initial glaucoma treatment: the glaucoma initial treatment study randomised clinical trial. 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