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Die meisten Irisrekonstruktionen gehen zus\u00e4tzlich mit einer Aphakiekorrektur durch sekund\u00e4re Linsenimplantation einher. Auch wenn prim\u00e4re Ziele die Herstellung einer Pupille sowie die Besserung des Blendungsempfindens, der Kontrastsensitivit\u00e4t und der Sehsch\u00e4rfe sind, spielt das \u00e4sthetische Ergebnis eine nicht zu vernachl\u00e4ssigende Rolle.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Ziel der Arbeit<\/jats:title>\n                <jats:p>Dargestellt werden funktionelle und \u00e4sthetische Ergebnisse nach Austausch von Aniridie-IOL-Implantaten gegen eine individuell angefertigte k\u00fcnstliche Iris in Kombination mit einer IOL.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Material und Methoden<\/jats:title>\n                <jats:p>In dieser retrospektiven Studie mit 7\u00a0Augen von 7\u00a0Patienten wurde eine Irisblenden-IOL (Morcher GmbH, Stuttgart) aus medizinischen Gr\u00fcnden (Subluxation) gegen eine individuell hergestellte k\u00fcnstliche Iris aus Silikon (Artificial<jats:italic>Iris<\/jats:italic>, HumanOptics, Erlangen) in Kombination mit einer angen\u00e4hten IOL ausgetauscht. Die Nachbeobachtungszeit betrug mindestens 3\u00a0Monate. Bestkorrigierter Fernvisus (BCVA), Endothelzellzahl (ECC), Komplikationen, Blendungsempfinden, das \u00e4sthetische Ergebnis und die Patientenzufriedenheit wurden evaluiert.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Ergebnisse<\/jats:title>\n                <jats:p>BCVA und ECC zeigten keine statistisch signifikante \u00c4nderung zwischen pr\u00e4- und postoperativ (<jats:italic>p<\/jats:italic>\u202f&gt;\u20090,05). Es zeigte sich eine Dezentrierung des Iris-IOL-Implantats von 0,27\u202f\u00b1\u20090,19\u202fmm 3\u00a0Monate postoperativ. Auf einer visuellen Analogskala (VAS) von\u00a01 bis\u00a010 (1\u202f=\u2009gar nicht bis 10\u202f=\u2009extrem zufrieden) wurde die Zufriedenheit mit dem Gesamtergebnis mit 8,6\u202f\u00b1\u20092,5 bewertet. Das subjektive Blendungsempfinden besserte sich auf 5,6\u202f\u00b1\u20093,5 und die subjektive \u00e4sthetische Beeintr\u00e4chtigung auf 2,4\u202f\u00b1\u20092,0 auf der VAS (1\u202f=\u2009gar nicht bis 10\u202f=\u2009extrem stark). Die postoperativen Komplikationen umfassten eine vor\u00fcbergehende intraokulare Hypotonie in zwei, einen Druckanstieg in zwei, eine Netzhautabl\u00f6sung und eine transiente Glask\u00f6rperblutung jeweils in einem Auge. Sechs von sieben Patienten w\u00fcrden den Eingriff wiederholen.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Schlussfolgerung<\/jats:title>\n                <jats:p>Im Vergleich zu einem starren Aniridie-IOL-Implantat bietet der Austausch gegen eine individuell angefertigte k\u00fcnstliche Iris in Kombination mit einer IOL neben einem guten funktionellen gleichzeitig auch ein \u00e4sthetisch ansprechendes Ergebnis.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00347-021-01447-9","type":"journal-article","created":{"date-parts":[[2021,7,8]],"date-time":"2021-07-08T12:05:21Z","timestamp":1625745921000},"page":"181-189","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Austausch von Aniridie-IOL gegen individuelle Iris-IOL-Implantate","Exchange of aniridia IOLs for customized iris IOL implants"],"prefix":"10.1007","volume":"119","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6670-2107","authenticated-orcid":false,"given":"C.","family":"Mayer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Scharf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Khoramnia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,7,8]]},"reference":[{"key":"1447_CR1","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1016\/j.jcrs.2011.11.015","volume":"38","author":"W Ayliffe","year":"2012","unstructured":"Ayliffe\u00a0W, Groth\u00a0SL, Sponsel\u00a0WE (2012) Small-incision insertion of artificial iris prostheses. 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HumanOptics. D.\u00a0Scharf gibt an, dass kein Interessenkonflikt besteht. R.\u00a0Khoramnia erh\u00e4lt Vortragshonorare und Reisekostenerstattungen von Fa. Ophtec.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"Alle beschriebenen Untersuchungen am Menschen oder an menschlichem Gewebe wurden mit Zustimmung der zust\u00e4ndigen Ethikkommission (535\/15 S), im Einklang mit nationalem Recht sowie gem\u00e4\u00df der Deklaration von Helsinki von 1975 (in der aktuellen, \u00fcberarbeiteten Fassung) durchgef\u00fchrt. Von allen beteiligten Patienten liegt eine Einverst\u00e4ndniserkl\u00e4rung vor.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}