{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T16:27:54Z","timestamp":1747153674791,"version":"3.40.5"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2021,12,3]],"date-time":"2021-12-03T00:00:00Z","timestamp":1638489600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,12,3]],"date-time":"2021-12-03T00:00:00Z","timestamp":1638489600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e4tsklinikum Ulm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ophthalmologie"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:sec>\n                <jats:title>Hintergrund<\/jats:title>\n                <jats:p>Die Lebensqualit\u00e4t von Glaukompatienten wird von vielen Faktoren beeinflusst. Insbesondere die Aktivit\u00e4t wird durch die chronische Erkrankung beeintr\u00e4chtigt. Diese Studie evaluiert Ver\u00e4nderungen der Lebensqualit\u00e4t \u00fcber Aktivit\u00e4tseinschr\u00e4nkungen in einem Zeitraum von 8\u00a0Jahren.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methoden<\/jats:title>\n                <jats:p>Dreiundvierzig Patienten mit glaukomat\u00f6sem Papillenschaden wurden in diese retrospektive longitudinale Beobachtungsstudie eingeschlossen. Ver\u00e4nderungen des Intraokulardrucks (IOD) und der bestkorrigierten Sehsch\u00e4rfe (BCVA) sowie Gesichtsfeldparameter, Anzahl der den Intraokulardruck (IOD) senkenden Medikation und der durchgef\u00fchrten augendrucksenkenden Operationen wurden \u00fcber einen Zeitraum von 8\u00a0Jahren erhoben. Die Lebensqualit\u00e4t und Aktivit\u00e4tseinschr\u00e4nkung der Patienten wurden mit dem Rasch-kalibrierten Fragebogen \u201eGlaucoma Activity Limitation\u00a09\u201c (GAL-9) bei Einschluss und 8\u00a0Jahre sp\u00e4ter erhoben.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Ergebnisse<\/jats:title>\n                <jats:p>Die Sehsch\u00e4rfe des besseren Auges \u00e4nderte sich von 0,16\u202f\u00b1\u20090,22 auf 0,21\u202f\u00b1\u20090,14 logMAR, die des schlechteren Auges von 0,27\u202f\u00b1\u20090,25 auf 1,39\u202f\u00b1\u20091,1 logMAR. Die mittlere Defekttiefe im Gesichtsfeld (\u201emean deviation\u201c [MD]) des besseren Auges entwickelte sich von \u22122,39\u202f\u00b1\u20094,55\u202fdB auf \u22124,83\u202f\u00b1\u20095,09\u202fdB, die des schlechteren Auges von \u22128,86\u202f\u00b1\u20095,86\u202fdB auf \u221212,05\u202f\u00b1\u20098,07\u202fdB. Die Werte des kalibrierten GAL\u20119 zeigten eine Ver\u00e4nderung von \u22122,39\u202f\u00b1\u20092,14 auf \u22121,38\u202f\u00b1\u20092,78 (negativere Werte in der spezifischen Rasch-Analyse bedeuten eine bessere Lebensqualit\u00e4t), was im Summenscore einer \u00c4nderung des Gesamtwertes von 79,17\u202f\u00b1\u200919,63 auf 69,22\u202f\u00b1\u200927,95 entspricht. Diese Ver\u00e4nderungen korrelierten signifikant mit der MD in der Folgeuntersuchung nach 8\u00a0Jahren, insbesondere am schlechteren Auge (r\u202f=\u20090,43). Auch in einer Regressionsanalyse konnte der Einfluss der MD auf die Entwicklung der Lebensqualit\u00e4t gut vorhergesagt werden.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Zusammenfassung<\/jats:title>\n                <jats:p>Die Lebensqualit\u00e4t bei an Glaukom erkrankten Patienten nimmt im Laufe der Zeit signifikant ab. Ver\u00e4nderungen des Gesichtsfeldes, insbesondere am schlechteren Auge, haben einen gro\u00dfen Einfluss. Sorgf\u00e4ltige Therapie, gerade des Auges mit ausgepr\u00e4gterem glaukomat\u00f6sem Schaden, ist daher von gro\u00dfer Wichtigkeit.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00347-021-01535-w","type":"journal-article","created":{"date-parts":[[2021,12,3]],"date-time":"2021-12-03T13:03:53Z","timestamp":1638536633000},"page":"599-604","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Ver\u00e4nderungen der Lebensqualit\u00e4t von Glaukompatienten \u00fcber einen Zeitraum von 8\u00a0Jahren","Changes in quality of life of glaucoma patients over a\u00a0period of 8 years"],"prefix":"10.1007","volume":"119","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3199-0276","authenticated-orcid":false,"given":"S. F.","family":"Koenig","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. W.","family":"Hirneiss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,12,3]]},"reference":[{"issue":"11","key":"1535_CR1","doi-asserted-by":"publisher","first-page":"2081","DOI":"10.1016\/j.ophtha.2014.05.013","volume":"121","author":"YC Tham","year":"2014","unstructured":"Tham\u00a0YC et al (2014) Global prevalence of glaucoma and projections of glaucoma burden through 2040: a\u00a0systematic review and meta-analysis. Ophthalmology 121(11):2081\u20132090","journal-title":"Ophthalmology"},{"issue":"18","key":"1535_CR2","doi-asserted-by":"publisher","first-page":"1901","DOI":"10.1001\/jama.2014.3192","volume":"311","author":"RN Weinreb","year":"2014","unstructured":"Weinreb\u00a0RN, Aung\u00a0T, Medeiros\u00a0FA (2014) The pathophysiology and treatment of glaucoma: a\u00a0review. JAMA 311(18):1901\u20131911","journal-title":"JAMA"},{"issue":"1","key":"1535_CR3","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1097\/IJG.0b013e3181752c83","volume":"18","author":"I Goldberg","year":"2009","unstructured":"Goldberg\u00a0I et al (2009) Assessing quality of life in patients with glaucoma using the Glaucoma Quality of Life-15 (GQL-15) questionnaire. J\u00a0Glaucoma 18(1):6\u201312","journal-title":"J Glaucoma"},{"issue":"2","key":"1535_CR4","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1016\/j.ajo.2007.04.048","volume":"144","author":"HD Jampel","year":"2007","unstructured":"Jampel\u00a0HD et\u00a0al (2007) Depression and mood indicators in newly diagnosed glaucoma patients. Am J Ophthalmol 144(2):238\u2013244","journal-title":"Am J Ophthalmol"},{"issue":"5","key":"1535_CR5","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1016\/S0161-6420(00)00624-2","volume":"108","author":"NK Janz","year":"2001","unstructured":"Janz\u00a0NK et\u00a0al (2001) Quality of life in newly diagnosed glaucoma patients : the Collaborative Initial Glaucoma Treatment Study. Ophthalmology 108(5):887\u2013897 (discussion 898)","journal-title":"Ophthalmology"},{"key":"1535_CR6","volume-title":"Terminology and guidelines for glaucoma","author":"EGS","year":"2020","unstructured":"EGS (2020) Terminology and guidelines for glaucoma, 5.\u00a0Aufl.","edition":"5"},{"issue":"3","key":"1535_CR7","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1097\/00061198-199606000-00001","volume":"5","author":"TJ Zimmerman","year":"1996","unstructured":"Zimmerman\u00a0TJ, Karunaratne\u00a0N, Fechtner\u00a0RD (1996) Glaucoma: outcomeology (part I, II). J\u00a0Glaucoma 5(3):151","journal-title":"J Glaucoma"},{"issue":"6","key":"1535_CR8","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.1016\/j.ajo.2007.02.022","volume":"143","author":"R McKean-Cowdin","year":"2007","unstructured":"McKean-Cowdin\u00a0R et al (2007) Severity of visual field loss and health-related quality of life. Am J Ophthalmol 143(6):1013\u20131023","journal-title":"Am J Ophthalmol"},{"issue":"5","key":"1535_CR9","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1136\/bjo.83.5.546","volume":"83","author":"P Nelson","year":"1999","unstructured":"Nelson\u00a0P, Aspinall\u00a0P, O\u2019Brien\u00a0C (1999) Patients\u2019 perception of visual impairment in glaucoma: a\u00a0pilot study. Br J Ophthalmol 83(5):546\u2013552","journal-title":"Br J Ophthalmol"},{"issue":"2","key":"1535_CR10","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1097\/00061198-200304000-00009","volume":"12","author":"P Nelson","year":"2003","unstructured":"Nelson\u00a0P et\u00a0al (2003) Quality of life in glaucoma and its relationship with visual function. J\u00a0Glaucoma 12(2):139\u2013150","journal-title":"J Glaucoma"},{"key":"1535_CR11","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/1471-2415-8-2","volume":"8","author":"P Severn","year":"2008","unstructured":"Severn\u00a0P et\u00a0al (2008) Which quality of life score is best for glaucoma patients and why? BMC Ophthalmol 8:2","journal-title":"BMC Ophthalmol"},{"issue":"7","key":"1535_CR12","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1097\/IJG.0b013e318163bdd1","volume":"17","author":"S Skalicky","year":"2008","unstructured":"Skalicky\u00a0S, Goldberg\u00a0I (2008) Depression and quality of life in patients with glaucoma: a\u00a0cross-sectional analysis using the Geriatric Depression Scale-15, assessment of function related to vision, and the Glaucoma Quality of Life-15. J\u00a0Glaucoma 17(7):546\u2013551","journal-title":"J Glaucoma"},{"issue":"10","key":"1535_CR13","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1007\/s00347-011-2402-1","volume":"108","author":"C Hirneiss","year":"2011","unstructured":"Hirneiss\u00a0C et al (2011) Measurement of glaucoma-specific functionality with the GQL-15 and correlation with parameters of visual function. Ophthalmologe 108(10):939\u2013946","journal-title":"Ophthalmologe"},{"issue":"4","key":"1535_CR14","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1080\/09286580802419736","volume":"15","author":"RW Massof","year":"2008","unstructured":"Massof\u00a0RW (2008) Moving toward scientific measurements of quality of life. Ophthalmic Epidemiol 15(4):209\u2013211","journal-title":"Ophthalmic Epidemiol"},{"issue":"7","key":"1535_CR15","doi-asserted-by":"publisher","first-page":"E836","DOI":"10.1097\/OPX.0b013e3181ae1ec7","volume":"86","author":"VK Gothwal","year":"2009","unstructured":"Gothwal\u00a0VK et\u00a0al (2009) Rasch analysis of the quality of life and vision function questionnaire. Optom Vis Sci 86(7):E836\u201344","journal-title":"Optom Vis Sci"},{"issue":"9","key":"1535_CR16","doi-asserted-by":"publisher","first-page":"1505","DOI":"10.1016\/j.ophtha.2005.03.028","volume":"112","author":"LG Hyman","year":"2005","unstructured":"Hyman\u00a0LG et al (2005) Treatment and vision-related quality of life in the early manifest glaucoma trial. Ophthalmology 112(9):1505\u20131513","journal-title":"Ophthalmology"},{"issue":"2","key":"1535_CR17","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1097\/00061198-200204000-00012","volume":"11","author":"HD Jampel","year":"2002","unstructured":"Jampel\u00a0HD et\u00a0al (2002) Glaucoma patients\u2019 assessment of their visual function and quality of life. J\u00a0Glaucoma 11(2):154\u2013163","journal-title":"J Glaucoma"},{"issue":"1","key":"1535_CR18","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1038\/sj.eye.6700036","volume":"16","author":"M Iester","year":"2002","unstructured":"Iester\u00a0M, Zingirian\u00a0M (2002) Quality of life in patients with early, moderate and advanced glaucoma. Eye (Lond) 16(1):44\u201349","journal-title":"Eye (Lond)"},{"issue":"20","key":"1535_CR19","doi-asserted-by":"publisher","first-page":"2154","DOI":"10.1016\/j.visres.2008.05.022","volume":"48","author":"KR Huxlin","year":"2008","unstructured":"Huxlin\u00a0KR (2008) Perceptual plasticity in damaged adult visual systems. Vision Res 48(20):2154\u20132166","journal-title":"Vision Res"},{"issue":"11","key":"1535_CR20","doi-asserted-by":"publisher","first-page":"1954","DOI":"10.1016\/S0161-6420(01)00874-0","volume":"108","author":"NK Janz","year":"2001","unstructured":"Janz\u00a0NK et\u00a0al (2001) The Collaborative Initial Glaucoma Treatment Study: interim quality of life findings after initial medical or surgical treatment of glaucoma. Ophthalmology 108(11):1954\u20131965","journal-title":"Ophthalmology"},{"issue":"6","key":"1535_CR21","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1097\/IJG.0000000000000372","volume":"25","author":"K Hirooka","year":"2016","unstructured":"Hirooka\u00a0K et al (2016) The relationship between vision-related quality of life and visual function in glaucoma patients. J\u00a0Glaucoma 25(6):505\u2013509","journal-title":"J Glaucoma"},{"issue":"3","key":"1535_CR22","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1097\/01.icu.0000120721.72077.b9","volume":"15","author":"GC Brown","year":"2004","unstructured":"Brown\u00a0GC (2004) One eye versus two: a\u00a0value-based approach. Curr Opin Ophthalmol 15(3):165\u2013166","journal-title":"Curr Opin Ophthalmol"},{"issue":"2","key":"1535_CR23","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/j.ophtha.2014.08.014","volume":"122","author":"FA Medeiros","year":"2015","unstructured":"Medeiros\u00a0FA et\u00a0al (2015) Longitudinal changes in quality of life and rates of progressive visual field loss in glaucoma patients. Ophthalmology 122(2):293\u2013301","journal-title":"Ophthalmology"},{"issue":"4","key":"1535_CR24","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1001\/jamaophthalmol.2013.2602","volume":"131","author":"R Lisboa","year":"2013","unstructured":"Lisboa\u00a0R et al (2013) Association between rates of binocular visual field loss and vision-related quality of life in patients with glaucoma. JAMA Ophthalmol 131(4):486\u2013494","journal-title":"JAMA Ophthalmol"},{"issue":"6","key":"1535_CR25","doi-asserted-by":"publisher","first-page":"1029","DOI":"10.1016\/j.ajo.2004.07.003","volume":"138","author":"C Boden","year":"2004","unstructured":"Boden\u00a0C et\u00a0al (2004) Patterns of glaucomatous visual field progression identified by three progression criteria. Am J Ophthalmol 138(6):1029\u20131036","journal-title":"Am J Ophthalmol"},{"issue":"4","key":"1535_CR26","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1016\/0002-9394(84)90128-4","volume":"98","author":"FS Mikelberg","year":"1984","unstructured":"Mikelberg\u00a0FS, Drance\u00a0SM (1984) The mode of progression of visual field defects in glaucoma. Am J Ophthalmol 98(4):443\u2013445","journal-title":"Am J Ophthalmol"},{"issue":"2","key":"1535_CR27","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1016\/S0161-6420(02)01742-6","volume":"110","author":"I Sumi","year":"2003","unstructured":"Sumi\u00a0I et\u00a0al (2003) The relationship between visual disability and visual field in patients with glaucoma. Ophthalmology 110(2):332\u2013339","journal-title":"Ophthalmology"}],"container-title":["Die Ophthalmologie"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00347-021-01535-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00347-021-01535-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00347-021-01535-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,8]],"date-time":"2022-06-08T18:32:49Z","timestamp":1654713169000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00347-021-01535-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,3]]},"references-count":27,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["1535"],"URL":"https:\/\/doi.org\/10.1007\/s00347-021-01535-w","relation":{},"ISSN":["2731-720X","2731-7218"],"issn-type":[{"type":"print","value":"2731-720X"},{"type":"electronic","value":"2731-7218"}],"subject":[],"published":{"date-parts":[[2021,12,3]]},"assertion":[{"value":"22 September 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 October 2021","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 November 2021","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 December 2021","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"S.F.\u00a0Koenig und C.W.\u00a0Hirneiss geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}