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Der vordere Augenabschnitt sowie der hintere Augenabschnitt in Mydriasis wurden augen\u00e4rztlich untersucht. Von beiden Augen wurde zus\u00e4tzlich ein Schirmer-Tr\u00e4nenstreifen auf SARS-CoV-2-RNA analysiert.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Ergebnisse<\/jats:title>\n                <jats:p>Es wurden 37\u00a0Patienten eingeschlossen. Am vorderen Augenabschnitt zeigten sich Chemosis\u00a0(5), Hyposphagma\u00a0(2) und Konjunktivitis\u00a0(1). Bei 11\u00a0Patienten zeigten sich vaskul\u00e4re Alterationen und m\u00f6glicherweise krankheitsspezifische Manifestationen am Augenhintergrund in einem oder beiden Augen: retinale Blutungen\u00a0(5), Cotton-Wool-Spots\u00a0(5) und Tortuositas\u00a0(5). Bei einem Patienten fand sich ein Arterienastverschluss, bei einem anderen Patienten ein Venenastverschluss. Zwei Patienten hatten einen positiven Bindehautabstrich in einem oder beiden Augen.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Diskussion<\/jats:title>\n                <jats:p>Die in dieser Studie beschriebenen Ver\u00e4nderungen des vorderen Augenabschnittes sind in einer Vielzahl chinesischer Studien vorbeschrieben, jedoch nicht spezifisch f\u00fcr COVID-19. Zudem konnten diverse vaskul\u00e4re Funduspathologien gefunden werden, welche sich signifikant h\u00e4ufiger bei COVID-19-Patienten zeigten als bei einer gesunden Vergleichskohorte. Es bleibt unklar, ob diese Ver\u00e4nderungen direkt durch SARS-CoV\u20112 ausgel\u00f6st werden oder ob sie auf systemischen Komorbidit\u00e4ten basieren. SARS-CoV-2-Viruspr\u00e4valenz in Tr\u00e4nenfl\u00fcssigkeiten ist m\u00f6glich.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00347-022-01581-y","type":"journal-article","created":{"date-parts":[[2022,1,28]],"date-time":"2022-01-28T16:02:33Z","timestamp":1643385753000},"page":"807-812","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Okul\u00e4re Manifestationen bei COVID-19-Patienten","Ocular manifestations in patients with COVID-19"],"prefix":"10.1007","volume":"119","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3399-4411","authenticated-orcid":false,"given":"Kristin","family":"H\u00f6sel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claus","family":"von der Burchard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domagoj","family":"Schunk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeanette","family":"Franzenburg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Bahmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Derk","family":"Frank","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justina","family":"Dargvainiene","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johann B.","family":"Roider","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,1,28]]},"reference":[{"key":"1581_CR1","doi-asserted-by":"publisher","first-page":"100618","DOI":"10.1016\/j.cpcardiol.2020.100618","volume":"45","author":"S Zaim","year":"2020","unstructured":"Zaim\u00a0S, Chong\u00a0JH, Sankaranarayanan\u00a0V et al (2020) COVID-19 and multiorgan response. 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Die Zustimmung durch die lokale Ethikkommission der Christian-Albrechts-Universit\u00e4t zu Kiel lag vor Beginn vor (Protokoll Nr. D 469\/20). Von allen beteiligten Patienten liegt eine Einverst\u00e4ndniserkl\u00e4rung vor. Eine Registrierung im Deutschen Register f\u00fcr Klinische Studien (DRKS) ist vorab erfolgt (Protokoll Nr. DRKS00021416). Dieser Beitrag beinhaltet keine Studien an Tieren.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}