{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T10:44:11Z","timestamp":1746701051090},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ophthalmologie"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1007\/s00347-022-01606-6","type":"journal-article","created":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T13:17:20Z","timestamp":1648819040000},"page":"952-957","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Hornhautepitheldicke bei Keratokonuspatienten im Vergleich zu gesunden Kontrollen"],"prefix":"10.1007","volume":"119","author":[{"given":"Larissa","family":"Lahme","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens Julian","family":"Storp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raphael","family":"Diener","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Eter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uwe","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin Dominik","family":"Leclaire","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maged","family":"Alnawaiseh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,4,1]]},"reference":[{"key":"1606_CR1","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1111\/aos.12647","volume":"93","author":"S Kaya","year":"2015","unstructured":"Kaya\u00a0S, Schmidl\u00a0D, Schmetterer\u00a0L et al (2015) Effect of hyaluronic acid on tear film thickness as assessed with ultra-high resolution optical coherence tomography. Acta Ophthalmol 93:439\u2013443. https:\/\/doi.org\/10.1111\/aos.12647","journal-title":"Acta Ophthalmol"},{"key":"1606_CR2","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1097\/00003226-199705000-00016","volume":"16","author":"MC Kenney","year":"1997","unstructured":"Kenney\u00a0MC, Nesburn\u00a0AB, Burgeson\u00a0RE et\u00a0al (1997) Abnormalities of the extracellular matrix in keratoconus corneas. Cornea 16:345\u2013351","journal-title":"Cornea"},{"key":"1606_CR3","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/0039-6257(84)90094-8","volume":"28","author":"JH Krachmer","year":"1984","unstructured":"Krachmer\u00a0JH, Feder\u00a0RS, Belin\u00a0MW (1984) Keratoconus and related noninflammatory corneal thinning disorders. Surv Ophthalmol 28:293\u2013322. https:\/\/doi.org\/10.1016\/0039-6257(84)90094-8","journal-title":"Surv Ophthalmol"},{"key":"1606_CR4","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0112696","author":"SJ Lang","year":"2014","unstructured":"Lang\u00a0SJ, Bischoff\u00a0M, B\u00f6hringer\u00a0D et\u00a0al (2014) Analysis of the changes in keratoplasty indications and preferred techniques. Plos One. https:\/\/doi.org\/10.1371\/journal.pone.0112696","journal-title":"Plos One"},{"key":"1606_CR5","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1016\/j.jcrs.2015.09.021","volume":"42","author":"Y Li","year":"2016","unstructured":"Li\u00a0Y, Chamberlain\u00a0W, Tan\u00a0O et\u00a0al (2016) Subclinical keratoconus detection by pattern analysis of corneal and epithelial thickness maps with optical coherence tomography. J\u00a0Cataract Refract Surg 42:284\u2013295. https:\/\/doi.org\/10.1016\/j.jcrs.2015.09.021","journal-title":"J Cataract Refract Surg"},{"key":"1606_CR6","doi-asserted-by":"publisher","first-page":"2425","DOI":"10.1016\/j.ophtha.2012.06.023","volume":"119","author":"Y Li","year":"2012","unstructured":"Li\u00a0Y, Tan\u00a0O, Brass\u00a0R et al (2012) Corneal epithelial thickness mapping by fourier-domain optical coherence tomography in normal and keratoconic eyes. Ophthalmology 119:2425\u20132433. https:\/\/doi.org\/10.1016\/j.ophtha.2012.06.023","journal-title":"Ophthalmology"},{"key":"1606_CR7","doi-asserted-by":"publisher","first-page":"1282","DOI":"10.1097\/ICO.0000000000000266","volume":"33","author":"B Lopes","year":"2014","unstructured":"Lopes\u00a0B, Ramos\u00a0I, Ambr\u00f3sio\u00a0RJ (2014) Corneal densitometry in keratoconus. Cornea 33:1282\u20131286. https:\/\/doi.org\/10.1097\/ICO.0000000000000266","journal-title":"Cornea"},{"key":"1606_CR8","doi-asserted-by":"publisher","first-page":"571","DOI":"10.3928\/1081597X-20080601-05","volume":"24","author":"DZ Reinstein","year":"2008","unstructured":"Reinstein\u00a0DZ, Archer\u00a0TJ, Gobbe\u00a0M et al (2008) Epithelial thickness in the normal cornea: three-dimensional display with very high frequency ultrasound. J\u00a0Refract Surg 24:571\u2013581","journal-title":"J Refract Surg"},{"key":"1606_CR9","doi-asserted-by":"publisher","first-page":"776","DOI":"10.3928\/1081597X-20090813-04","volume":"25","author":"DZ Reinstein","year":"2009","unstructured":"Reinstein\u00a0DZ, Archer\u00a0TJ, Gobbe\u00a0M et al (2009) Stromal thickness in the normal cornea: three-dimensional display with artemis very high-frequency digital ultrasound. J\u00a0Refract Surg 25:776\u2013786. https:\/\/doi.org\/10.3928\/1081597X-20090813-04","journal-title":"J Refract Surg"},{"key":"1606_CR10","doi-asserted-by":"publisher","first-page":"604","DOI":"10.3928\/1081597X-20090610-06","volume":"25","author":"DZ Reinstein","year":"2009","unstructured":"Reinstein\u00a0DZ, Archer\u00a0TJ, Gobbe\u00a0M (2009) Corneal epithelial thickness profile in the diagnosis of keratoconus. J\u00a0Refract Surg 25:604\u2013610. https:\/\/doi.org\/10.3928\/1081597X-20090610-06","journal-title":"J Refract Surg"},{"key":"1606_CR11","doi-asserted-by":"publisher","first-page":"259","DOI":"10.3928\/1081597X-20100218-01","volume":"26","author":"DZ Reinstein","year":"2010","unstructured":"Reinstein\u00a0DZ, Gobbe\u00a0M, Archer\u00a0TJ et al (2010) Epithelial, stromal, and total corneal thickness in keratoconus: three-dimensional display with artemis very-high frequency digital ultrasound. J\u00a0Refract Surg 26:259\u2013271. https:\/\/doi.org\/10.3928\/1081597X-20100218-01","journal-title":"J Refract Surg"},{"key":"1606_CR12","doi-asserted-by":"publisher","first-page":"173","DOI":"10.3928\/1081597X-20130129-08","volume":"29","author":"KM Rocha","year":"2013","unstructured":"Rocha\u00a0KM, Straziota\u00a0CP, Stulting\u00a0RD, Randleman\u00a0JB (2013) Spectral-domain OCT analysis of regional epithelial thickness profiles in keratoconus, postoperative corneal ectasia, and normal eyes. J\u00a0Refract Surg 29:173\u2013179. https:\/\/doi.org\/10.3928\/1081597X-20130129-08","journal-title":"J Refract Surg"},{"key":"1606_CR13","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000008314","author":"MM Samy","year":"2017","unstructured":"Samy\u00a0MM, Shaaban\u00a0YM, Badran\u00a0TAF (2017) Age- and sex-related differences in corneal epithelial thickness measured with spectral domain anterior segment optical coherence tomography among Egyptians. Medicine. https:\/\/doi.org\/10.1097\/MD.0000000000008314","journal-title":"Medicine"},{"key":"1606_CR14","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1001\/archopht.116.1.62","volume":"116","author":"S Sawaguchi","year":"1998","unstructured":"Sawaguchi\u00a0S, Fukuchi\u00a0T, Abe\u00a0H et al (1998) Three-dimensional scanning electron microscopic study of keratoconus corneas. Arch Ophthalmol 116:62\u201368. https:\/\/doi.org\/10.1001\/archopht.116.1.62","journal-title":"Arch Ophthalmol"},{"key":"1606_CR15","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/j.ajo.2018.09.008","volume":"197","author":"R Sella","year":"2019","unstructured":"Sella\u00a0R, Zangwill\u00a0LM, Weinreb\u00a0RN, Afshari\u00a0NA (2019) Repeatability and reproducibility of corneal epithelial thickness mapping with spectral-domain optical coherence tomography in normal and diseased cornea eyes. Am J Ophthalmol 197:88\u201397. https:\/\/doi.org\/10.1016\/j.ajo.2018.09.008","journal-title":"Am J Ophthalmol"},{"key":"1606_CR16","doi-asserted-by":"publisher","first-page":"1580","DOI":"10.1167\/iovs.13-12578","volume":"55","author":"RH Silverman","year":"2014","unstructured":"Silverman\u00a0RH, Urs\u00a0R, RoyChoudhury\u00a0A et al (2014) Epithelial remodeling as basis for machine-based identification of Keratoconus. Invest Ophthalmol Vis Sci 55:1580\u20131587. https:\/\/doi.org\/10.1167\/iovs.13-12578","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1606_CR17","doi-asserted-by":"publisher","first-page":"129","DOI":"10.5301\/ejo.5000850","volume":"27","author":"RH Silverman","year":"2017","unstructured":"Silverman\u00a0RH, Urs\u00a0R, RoyChoudhury\u00a0A et\u00a0al (2017) Combined tomography and epithelial thickness mapping for diagnosis of keratoconus. Eur J Ophthalmol 27:129\u2013134. https:\/\/doi.org\/10.5301\/ejo.5000850","journal-title":"Eur J Ophthalmol"},{"key":"1606_CR18","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1038\/sj.eye.6702286","volume":"21","author":"KH Weed","year":"2007","unstructured":"Weed\u00a0KH, MacEwen\u00a0CJ, Cox\u00a0A, McGhee\u00a0CNJ (2007) Quantitative analysis of corneal microstructure in keratoconus utilising in vivo confocal microscopy. Eye 21:614\u2013623. https:\/\/doi.org\/10.1038\/sj.eye.6702286","journal-title":"Eye"},{"key":"1606_CR19","doi-asserted-by":"publisher","DOI":"10.4172\/2161-038X.S6-001","author":"J Wheeler","year":"2012","unstructured":"Wheeler\u00a0J, Hauser\u00a0MA, Afshari\u00a0NA et\u00a0al (2012) The genetics of Keratoconus: a\u00a0review. Reprod Syst Sex Disord. https:\/\/doi.org\/10.4172\/2161-038X.S6-001","journal-title":"Reprod Syst Sex Disord"}],"container-title":["Die Ophthalmologie"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00347-022-01606-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00347-022-01606-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00347-022-01606-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T14:06:33Z","timestamp":1662127593000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00347-022-01606-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,1]]},"references-count":19,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["1606"],"URL":"https:\/\/doi.org\/10.1007\/s00347-022-01606-6","relation":{},"ISSN":["2731-720X","2731-7218"],"issn-type":[{"value":"2731-720X","type":"print"},{"value":"2731-7218","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,1]]},"assertion":[{"value":"25 November 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 February 2022","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 February 2022","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 April 2022","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"L.\u00a0Lahme, J.J.\u00a0Storp, R.\u00a0Diener, N.\u00a0Eter, U.\u00a0Hansen, M.D.\u00a0Leclaire und M.\u00a0Alnawaiseh geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"Die Analyse dieser retrospektiven Daten wurde durch die Ethik-Kommission der \u00c4rztekammer Westfalen-Lippe und der Westf\u00e4lischen Wilhelms-Universit\u00e4t genehmigt.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}