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Erfasst wurden das Vorliegen einer Erosio oder Ulkus, die Anwendung einer AMT, der HH-Status und die Grunderkrankung. Zielgr\u00f6\u00dfen waren die Epithelschlussrate innerhalb 4\u00a0Wochen und die Rezidivrate nach Epithelschluss. Die mediane Beobachtungszeit betrug 50\u00a0Monate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Ergebnisse<\/jats:title><jats:p>Ein Epithelschluss zeigte sich bei 73,6\u202f% und ein Rezidiv bei 27,4\u202f%. Eine AMT wurde signifikant h\u00e4ufiger bei Ulzera (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090,001) und Rezidiven (<jats:italic>p<\/jats:italic>\u202f=\u20090,048) angewandt. Ohne AMT ergab sich eine signifikant h\u00f6here Epithelschlussrate (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090,001) und schnellere Heilungstendenz (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090,001). Es bestand kein Unterschied zwischen der eigenen HH und dem TPL in der Epithelschlussrate (<jats:italic>p<\/jats:italic>\u202f=\u20090,47). Auf dem TPL zeigte sich eine signifikant h\u00f6here Rezidivrate (<jats:italic>p<\/jats:italic>\u202f=\u20090,004) und ein schnelleres Rezidivauftreten (<jats:italic>p<\/jats:italic>\u202f=\u20090,03), v.\u202fa. \u22646\u00a0Monate nach Epithelschluss. Die Grunderkrankungen zeigten einen signifikanten Unterschied in der Epithelschluss- (<jats:italic>p<\/jats:italic>\u202f=\u20090,02) und Rezidivrate (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090,001) mit h\u00f6chstem Erfolg bei HH-Dystrophien und geringstem bei kongenitaler Aniridie.<\/jats:p><\/jats:sec><jats:sec><jats:title>Schlussfolgerungen<\/jats:title><jats:p>Das AS stellt eine effektive Therapieoption bei therapieresistenten Epitheldefekten dar. Es zeigt auf dem TPL eine hohe Erfolgsrate bei zugleich h\u00f6herer Rezidivneigung. Bei simultaner AMT ist wegen der erh\u00f6hten Komplexit\u00e4t des zugrunde liegenden Problems\u00a0mit geringeren Erfolgsraten zu rechnen. 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