{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T13:19:51Z","timestamp":1773926391554,"version":"3.50.1"},"reference-count":56,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T00:00:00Z","timestamp":1704153600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T00:00:00Z","timestamp":1704153600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ophthalmologie"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Kongenitale geteilte melanozyt\u00e4re N\u00e4vi (CMN) des Ober- und Unterlids sind seltene pigmentierte Ver\u00e4nderungen der Augenlider. Diese Muttermale sind auch als \u201ekissing nevi\u201c, \u201epanda nevi\u201c, \u201esplit ocular nevi\u201c bekannt und wurden erstmals 1919 von Fuchs beschrieben. Aus der Literatur sind bisher etwa 120 solcher F\u00e4lle bekannt. CMN sind entweder seit der Geburt vorhanden (kleine N\u00e4vi finden sich bereits bei ca.\u00a01\u202f% der Neugeborenen), oder sie manifestieren sich \u00fcberwiegend im ersten Lebensjahrzehnt. Diese seltene melanozyt\u00e4re Ver\u00e4nderung der Augenlider sollte regelm\u00e4\u00dfig kontrolliert werden, denn gem\u00e4\u00df der Literatur kann es zu einer malignen Entartung kommen. Die tats\u00e4chliche Inzidenz daf\u00fcr ist jedoch sehr variabel und reicht von 2 bis 40\u202f%, je nach Dauer des Follow-up, mit durchschnittlich 14\u202f% auf die gesamte Lebensdauer. Zudem k\u00f6nnen CMN an den Augenlidern als kosmetisch st\u00f6rend empfunden werden und zu funktionellen Problemen des Auges f\u00fchren. Eine therapeutische Entfernung mittels Dermabrasion, Kryotherapie, Laserbehandlung oder chirurgische Exzision mit ophthalmoplastischer Deckung ist aufgrund des geringen Entartungsrisikos selten medizinisch indiziert. Sie kann aber bei sekund\u00e4rer Amblyopie bei Ptosis, Kompression der Puncta lacrimalia, Epiphora oder basierend auf einem kosmetischen Wunsch durchgef\u00fchrt werden. Notwendig wird die Therapie hingegen bei einer suspekten Erscheinungsform oder Beeintr\u00e4chtigung der Lidfunktion und um m\u00f6gliche H\u00e4nseleien und grausamen Spott bei Kindern zu vermeiden.<\/jats:p>","DOI":"10.1007\/s00347-023-01963-w","type":"journal-article","created":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T13:02:16Z","timestamp":1704200536000},"page":"116-122","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Therapeutisches Management eines \u201ekissing nevus\u201c des Augenlids","Therapeutic management of a\u00a0kissing nevus of the eyelid"],"prefix":"10.1007","volume":"121","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4877-8543","authenticated-orcid":false,"given":"P. 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