{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:38:06Z","timestamp":1790789886816,"version":"4.1.0"},"reference-count":72,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T00:00:00Z","timestamp":1705968000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T00:00:00Z","timestamp":1705968000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ophthalmologie"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1007\/s00347-023-01974-7","type":"journal-article","created":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T17:02:25Z","timestamp":1706029345000},"page":"93-104","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Retinale OCT-Biomarker und neurodegenerative Erkrankungen des zentralen Nervensystems jenseits der Alzheimer-Krankheit","Retinal OCT biomarkers and neurodegenerative diseases of the central nervous system beyond Alzheimer\u2019s disease"],"prefix":"10.1007","volume":"121","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7989-9420","authenticated-orcid":false,"given":"Susanne","family":"Hopf","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"T\u00fcscher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander K.","family":"Schuster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,1,23]]},"reference":[{"key":"1974_CR1","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1080\/14737159.2020.1731306","volume":"20","author":"F Baldacci","year":"2020","unstructured":"Baldacci\u00a0F, Mazzucchi\u00a0S, Della Vecchia\u00a0A, Giampietri\u00a0L, Giannini\u00a0N, Koronyo-Hamaoui\u00a0M et\u00a0al (2020) The path to biomarker-based diagnostic criteria for the spectrum of neurodegenerative diseases. Expert Rev Mol Diagn 20:421\u2013441. https:\/\/doi.org\/10.1080\/14737159.2020.1731306","journal-title":"Expert Rev Mol Diagn"},{"key":"1974_CR2","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1038\/s41580-021-00382-6","volume":"22","author":"I Malik","year":"2021","unstructured":"Malik\u00a0I, Kelley\u00a0CP, Wang\u00a0ET, Todd\u00a0PK (2021) Molecular mechanisms underlying nucleotide repeat expansion disorders. Nat Rev Mol Cell Biol 22:589\u2013607. https:\/\/doi.org\/10.1038\/s41580-021-00382-6","journal-title":"Nat Rev Mol Cell Biol"},{"key":"1974_CR3","doi-asserted-by":"publisher","first-page":"468","DOI":"10.3390\/diagnostics12020468","volume":"12","author":"AJ Augustin","year":"2022","unstructured":"Augustin\u00a0AJ, Atorf\u00a0J (2022) The value of Optical Coherence Tomography Angiography (OCT-A) in neurological diseases. Diagnostics 12:468. https:\/\/doi.org\/10.3390\/diagnostics12020468","journal-title":"Diagnostics"},{"key":"1974_CR4","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1212\/WNL.0000000000012125","volume":"97","author":"A Aytulun","year":"2021","unstructured":"Aytulun\u00a0A, Cruz-Herranz\u00a0A, Aktas\u00a0O, Balcer\u00a0LJ, Balk\u00a0L, Barboni\u00a0P et\u00a0al (2021) APOSTEL 2.0 recommendations for reporting quantitative optical coherence tomography studies. Neurology 97:68\u201379. https:\/\/doi.org\/10.1212\/WNL.0000000000012125","journal-title":"Neurology"},{"key":"1974_CR5","first-page":"736","volume":"31","author":"JB Jonas","year":"1990","unstructured":"Jonas\u00a0JB, M\u00fcller-Bergh\u00a0JA, Schl\u00f6tzer-Schrehardt\u00a0UM, Naumann\u00a0GO (1990) Histomorphometry of the human optic nerve. Invest Ophthalmol Vis Sci 31:736\u2013744","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1974_CR6","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1055\/a-1098-3466","volume":"237","author":"C Mardin","year":"2020","unstructured":"Mardin\u00a0C (2020) OCT-diagnostik beim glaukom: tipps & tricks. Klin Monbl Augenheilkd 237:539\u2013551. https:\/\/doi.org\/10.1055\/a-1098-3466","journal-title":"Klin Monbl Augenheilkd"},{"key":"1974_CR7","doi-asserted-by":"publisher","first-page":"OCT575","DOI":"10.1167\/iovs.15-18906","volume":"57","author":"JMD Gmeiner","year":"2016","unstructured":"Gmeiner\u00a0JMD, Schrems\u00a0WA, Mardin\u00a0CY, Laemmer\u00a0R, Kruse\u00a0FE, Schrems-Hoesl\u00a0LM (2016) Comparison of bruch\u2019s membrane opening minimum rim width and peripapillary retinal nerve fiber layer thickness in early glaucoma assessment. Invest Ophthalmol Vis Sci 57:OCT575\u2013OCT584. https:\/\/doi.org\/10.1167\/iovs.15-18906","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1974_CR8","doi-asserted-by":"publisher","first-page":"6596","DOI":"10.1167\/iovs.16-20561","volume":"57","author":"P Enders","year":"2016","unstructured":"Enders\u00a0P, Adler\u00a0W, Schaub\u00a0F, Hermann\u00a0MM, Dietlein\u00a0T, Cursiefen\u00a0C et\u00a0al (2016) Novel bruch\u2019s membrane opening minimum rim area equalizes disc size dependency and offers high diagnostic power for glaucoma. Invest Ophthalmol Vis Sci 57:6596\u20136603. https:\/\/doi.org\/10.1167\/iovs.16-20561","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1974_CR9","doi-asserted-by":"publisher","first-page":"526","DOI":"10.1364\/BOE.10.000526","volume":"10","author":"Z Chen","year":"2019","unstructured":"Chen\u00a0Z, Peng\u00a0P, Shen\u00a0H, Wei\u00a0H, Ouyang\u00a0P, Duan\u00a0X (2019) Region-segmentation strategy for bruch\u2019s membrane opening detection in spectral domain optical coherence tomography images. Biomed Opt Express 10:526\u2013538. https:\/\/doi.org\/10.1364\/BOE.10.000526","journal-title":"Biomed Opt Express"},{"key":"1974_CR10","doi-asserted-by":"publisher","first-page":"1120","DOI":"10.1016\/S1474-4422(22)00200-9","volume":"21","author":"A Petzold","year":"2022","unstructured":"Petzold\u00a0A, Fraser\u00a0CL, Abegg\u00a0M, Alroughani\u00a0R, Alshowaeir\u00a0D, Alvarenga\u00a0R et\u00a0al (2022) Diagnosis and classification of optic neuritis. Lancet Neurol 21:1120\u20131134. https:\/\/doi.org\/10.1016\/S1474-4422(22)00200-9","journal-title":"Lancet Neurol"},{"key":"1974_CR11","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1038\/nrneurol.2012.227","volume":"9","author":"A London","year":"2013","unstructured":"London\u00a0A, Benhar\u00a0I, Schwartz\u00a0M (2013) The retina as a\u00a0window to the brain-from eye research to CNS disorders. Nat Rev Neurol 9:44\u201353. https:\/\/doi.org\/10.1038\/nrneurol.2012.227","journal-title":"Nat Rev Neurol"},{"key":"1974_CR12","unstructured":"(2017) Stellungnahme des BVA, der DOG und der RG: OCT-Angiographie in Deutschland. https:\/\/www.springermedizin.de\/angiografie\/stellungnahme-des-bva-der-dog-und-der-rg-oct-angiographie-in-deu\/12220180. Zugegriffen: 16. Apr. 2023"},{"key":"1974_CR13","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1001\/jamaophthalmol.2020.5719","volume":"139","author":"JB Lin","year":"2021","unstructured":"Lin\u00a0JB, Apte\u00a0RS (2021) Seeing parkinson disease in the retina. JAMA Ophthalmol 139:189\u2013190. https:\/\/doi.org\/10.1001\/jamaophthalmol.2020.5719","journal-title":"JAMA Ophthalmol"},{"key":"1974_CR14","doi-asserted-by":"publisher","first-page":"2793","DOI":"10.1016\/j.visres.2004.06.009","volume":"44","author":"R Inzelberg","year":"2004","unstructured":"Inzelberg\u00a0R, Ramirez\u00a0JA, Nisipeanu\u00a0P, Ophir\u00a0A (2004) Retinal nerve fiber layer thinning in parkinson disease. Vision Res 44:2793\u20132797. https:\/\/doi.org\/10.1016\/j.visres.2004.06.009","journal-title":"Vision Res"},{"key":"1974_CR15","doi-asserted-by":"publisher","first-page":"197","DOI":"10.3233\/JPD-130306","volume":"4","author":"J-Y Lee","year":"2014","unstructured":"Lee\u00a0J\u2011Y, Ahn\u00a0J, Kim\u00a0TW, Jeon\u00a0BS (2014) Optical coherence tomography in parkinson\u2019s disease: is the retina a\u00a0biomarker? J\u00a0Parkinsons Dis 4:197\u2013204. https:\/\/doi.org\/10.3233\/JPD-130306","journal-title":"J Parkinsons Dis"},{"key":"1974_CR16","doi-asserted-by":"publisher","first-page":"4023","DOI":"10.1007\/s00415-020-10094-0","volume":"268","author":"L Huang","year":"2021","unstructured":"Huang\u00a0L, Wang\u00a0C, Wang\u00a0W, Wang\u00a0Y, Zhang\u00a0R (2021) The specific pattern of retinal nerve fiber layer thinning in parkinson\u2019s disease: a\u00a0systematic review and meta-analysis. J\u00a0Neurol 268:4023\u20134032. https:\/\/doi.org\/10.1007\/s00415-020-10094-0","journal-title":"J Neurol"},{"key":"1974_CR17","doi-asserted-by":"publisher","first-page":"4646","DOI":"10.1007\/s00415-020-10304-9","volume":"268","author":"L Huang","year":"2021","unstructured":"Huang\u00a0L, Zhang\u00a0D, Ji\u00a0J, Wang\u00a0Y, Zhang\u00a0R (2021) Central retina changes in parkinson\u2019s disease: a\u00a0systematic review and meta-analysis. J\u00a0Neurol 268:4646\u20134654. https:\/\/doi.org\/10.1007\/s00415-020-10304-9","journal-title":"J Neurol"},{"key":"1974_CR18","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1111\/ene.14613","volume":"28","author":"W-C Zhou","year":"2021","unstructured":"Zhou\u00a0W\u2011C, Tao\u00a0J\u2011X, Li\u00a0J (2021) Optical coherence tomography measurements as potential imaging biomarkers for parkinson\u2019s disease: a\u00a0systematic review and meta-analysis. Eur J Neurol 28:763\u2013774. https:\/\/doi.org\/10.1111\/ene.14613","journal-title":"Eur J Neurol"},{"key":"1974_CR19","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1002\/ana.25897","volume":"88","author":"I Ortu\u00f1o-Lizar\u00e1n","year":"2020","unstructured":"Ortu\u00f1o-Lizar\u00e1n\u00a0I, S\u00e1nchez-S\u00e1ez\u00a0X, Lax\u00a0P, Serrano\u00a0GE, Beach\u00a0TG, Adler\u00a0CH et\u00a0al (2020) Dopaminergic retinal cell loss and visual dysfunction in parkinson disease. Ann Neurol 88:893\u2013906. https:\/\/doi.org\/10.1002\/ana.25897","journal-title":"Ann Neurol"},{"key":"1974_CR20","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1002\/ana.25972","volume":"89","author":"J-Y Lee","year":"2021","unstructured":"Lee\u00a0J\u2011Y, Ahn\u00a0J, Shin\u00a0JY, Jeon\u00a0B (2021) Parafoveal change and dopamine loss in the retina with parkinson\u2019s disease. Ann Neurol 89:421\u2013422. https:\/\/doi.org\/10.1002\/ana.25972","journal-title":"Ann Neurol"},{"key":"1974_CR21","doi-asserted-by":"publisher","first-page":"e1003","DOI":"10.1212\/WNL.0000000000006157","volume":"91","author":"J Ahn","year":"2018","unstructured":"Ahn\u00a0J, Lee\u00a0J\u2011Y, Kim\u00a0TW, Yoon\u00a0EJ, Oh\u00a0S, Kim\u00a0YK et\u00a0al (2018) Retinal thinning associates with nigral dopaminergic loss in de novo parkinson disease. Neurology 91:e1003\u2013e1012. https:\/\/doi.org\/10.1212\/WNL.0000000000006157","journal-title":"Neurology"},{"key":"1974_CR22","doi-asserted-by":"publisher","first-page":"1437","DOI":"10.1007\/s10792-021-02133-0","volume":"42","author":"Y Kamata","year":"2022","unstructured":"Kamata\u00a0Y, Hara\u00a0N, Satou\u00a0T, Niida\u00a0T, Mukuno\u00a0K (2022) Investigation of the pathophysiology of the retina and choroid in parkinson\u2019s disease by optical coherence tomography. Int Ophthalmol 42:1437\u20131445. https:\/\/doi.org\/10.1007\/s10792-021-02133-0","journal-title":"Int Ophthalmol"},{"key":"1974_CR23","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-023-02653-x","author":"EE Christou","year":"2023","unstructured":"Christou\u00a0EE, Konitsiotis\u00a0S, Pamporis\u00a0K, Giannakis\u00a0A, Asproudis\u00a0C, Stefaniotou\u00a0M et\u00a0al (2023) Inner retinal layers\u2019 alterations of the microvasculature in early stages of parkinson\u2019s disease: a\u00a0cross sectional study. Int Ophthalmol. https:\/\/doi.org\/10.1007\/s10792-023-02653-x","journal-title":"Int Ophthalmol"},{"key":"1974_CR24","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1001\/jamaophthalmol.2020.5730","volume":"139","author":"CB Robbins","year":"2021","unstructured":"Robbins\u00a0CB, Thompson\u00a0AC, Bhullar\u00a0PK, Koo\u00a0HY, Agrawal\u00a0R, Soundararajan\u00a0S et\u00a0al (2021) Characterization of retinal microvascular and choroidal structural changes in parkinson disease. JAMA Ophthalmol 139:182\u2013188. https:\/\/doi.org\/10.1001\/jamaophthalmol.2020.5730","journal-title":"JAMA Ophthalmol"},{"key":"1974_CR25","doi-asserted-by":"publisher","first-page":"708700","DOI":"10.3389\/fnins.2021.708700","volume":"15","author":"A Murueta-Goyena","year":"2021","unstructured":"Murueta-Goyena\u00a0A, Barrenechea\u00a0M, Erramuzpe\u00a0A, Teijeira-Portas\u00a0S, Pengo\u00a0M, Ayala\u00a0U et\u00a0al (2021) Foveal remodeling of retinal microvasculature in parkinson\u2019s disease. Front Neurosci 15:708700. https:\/\/doi.org\/10.3389\/fnins.2021.708700","journal-title":"Front Neurosci"},{"key":"1974_CR26","doi-asserted-by":"publisher","first-page":"1930","DOI":"10.21037\/qims-20-460","volume":"10","author":"J Zou","year":"2020","unstructured":"Zou\u00a0J, Liu\u00a0K, Li\u00a0F, Xu\u00a0Y, Shen\u00a0L, Xu\u00a0H (2020) Combination of optical coherence tomography (OCT) and OCT angiography increases diagnostic efficacy of parkinson\u2019s disease. Quant Imaging Med Surg 10:1930\u20131939. https:\/\/doi.org\/10.21037\/qims-20-460","journal-title":"Quant Imaging Med Surg"},{"key":"1974_CR27","doi-asserted-by":"publisher","first-page":"785","DOI":"10.3233\/JPD-202324","volume":"12","author":"I van der Lijn","year":"2022","unstructured":"van der Lijn\u00a0I, de Haan\u00a0GA, Huizinga\u00a0F, van der Feen\u00a0FE, Rutgers\u00a0AWF, Stellingwerf\u00a0C et\u00a0al (2022) Self-reported visual complaints in people with parkinson\u2019s disease: a\u00a0systematic review. J\u00a0Parkinsons Dis 12:785\u2013806. https:\/\/doi.org\/10.3233\/JPD-202324","journal-title":"J Parkinsons Dis"},{"key":"1974_CR28","doi-asserted-by":"publisher","first-page":"206","DOI":"10.3389\/fneur.2017.00206","volume":"8","author":"CE Mendoza-Santiesteban","year":"2017","unstructured":"Mendoza-Santiesteban\u00a0CE, Gabilondo\u00a0I, Palma\u00a0JA, Norcliffe-Kaufmann\u00a0L, Kaufmann\u00a0H (2017) The retina in multiple system atrophy: systematic review and meta-analysis. Front Neurol 8:206. https:\/\/doi.org\/10.3389\/fneur.2017.00206","journal-title":"Front Neurol"},{"key":"1974_CR29","doi-asserted-by":"publisher","first-page":"2083","DOI":"10.1007\/s00415-019-09654-w","volume":"268","author":"A Cerver\u00f3","year":"2021","unstructured":"Cerver\u00f3\u00a0A, Casado\u00a0A, Riancho\u00a0J (2021) Retinal changes in amyotrophic lateral sclerosis: looking at the disease through a\u00a0new window. J\u00a0Neurol 268:2083\u20132089. https:\/\/doi.org\/10.1007\/s00415-019-09654-w","journal-title":"J Neurol"},{"key":"1974_CR30","doi-asserted-by":"publisher","first-page":"1557","DOI":"10.1007\/s00415-018-8863-2","volume":"265","author":"M Rohani","year":"2018","unstructured":"Rohani\u00a0M, Meysamie\u00a0A, Zamani\u00a0B, Sowlat\u00a0MM, Akhoundi\u00a0FH (2018) Reduced retinal nerve fiber layer (RNFL) thickness in ALS patients: a\u00a0window to disease progression. J\u00a0Neurol 265:1557\u20131562. https:\/\/doi.org\/10.1007\/s00415-018-8863-2","journal-title":"J Neurol"},{"key":"1974_CR31","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1007\/s00702-015-1483-4","volume":"123","author":"A H\u00fcbers","year":"2016","unstructured":"H\u00fcbers\u00a0A, M\u00fcller\u00a0HP, Dreyhaupt\u00a0J, B\u00f6hm\u00a0K, Lauda\u00a0F, Tumani\u00a0H et\u00a0al (2016) Retinal involvement in amyotrophic lateral sclerosis: a\u00a0study with optical coherence tomography and diffusion tensor imaging. J\u00a0Neural Transm 123:281\u2013287. https:\/\/doi.org\/10.1007\/s00702-015-1483-4","journal-title":"J Neural Transm"},{"key":"1974_CR32","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1002\/acn3.46","volume":"1","author":"M Ringelstein","year":"2014","unstructured":"Ringelstein\u00a0M, Albrecht\u00a0P, S\u00fcdmeyer\u00a0M, Harmel\u00a0J, M\u00fcller\u00a0A\u2011K, Keser\u00a0N et\u00a0al (2014) Subtle retinal pathology in amyotrophic lateral sclerosis. Ann Clin Transl Neurol 1:290\u2013297. https:\/\/doi.org\/10.1002\/acn3.46","journal-title":"Ann Clin Transl Neurol"},{"key":"1974_CR33","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1007\/s00415-018-8787-x","volume":"265","author":"A Abdelhak","year":"2018","unstructured":"Abdelhak\u00a0A, H\u00fcbers\u00a0A, B\u00f6hm\u00a0K, Ludolph\u00a0AC, Kassubek\u00a0J, Pinkhardt\u00a0EH (2018) In vivo assessment of retinal vessel pathology in amyotrophic lateral sclerosis. J\u00a0Neurol 265:949\u2013953. https:\/\/doi.org\/10.1007\/s00415-018-8787-x","journal-title":"J Neurol"},{"key":"1974_CR34","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1038\/eye.2011.291","volume":"26","author":"S Noval","year":"2012","unstructured":"Noval\u00a0S, Contreras\u00a0I, Sanz-Gallego\u00a0I, Manrique\u00a0RK, Arpa\u00a0J (2012) Ophthalmic features of friedreich ataxia. Eye 26:315\u2013320. https:\/\/doi.org\/10.1038\/eye.2011.291","journal-title":"Eye"},{"key":"1974_CR35","doi-asserted-by":"publisher","DOI":"10.1002\/mds.29277","author":"G Thomas-Black","year":"2022","unstructured":"Thomas-Black\u00a0G, Altmann\u00a0DR, Crook\u00a0H, Solanky\u00a0N, Carrasco\u00a0FP, Battiston\u00a0M et\u00a0al (2022) Multimodal analysis of the visual pathways in friedreich\u2019s ataxia reveals novel biomarkers. Mov Disord. https:\/\/doi.org\/10.1002\/mds.29277","journal-title":"Mov Disord"},{"key":"1974_CR36","doi-asserted-by":"publisher","first-page":"2457","DOI":"10.1007\/s00415-015-7869-2","volume":"262","author":"HM Kersten","year":"2015","unstructured":"Kersten\u00a0HM, Danesh-Meyer\u00a0HV, Kilfoyle\u00a0DH, Roxburgh\u00a0RH (2015) Optical coherence tomography findings in huntington\u2019s disease: a\u00a0potential biomarker of disease progression. J\u00a0Neurol 262:2457\u20132465. https:\/\/doi.org\/10.1007\/s00415-015-7869-2","journal-title":"J Neurol"},{"key":"1974_CR37","doi-asserted-by":"publisher","first-page":"73","DOI":"10.2147\/EB.S193026","volume":"12","author":"G Tsokolas","year":"2020","unstructured":"Tsokolas\u00a0G, Tsaousis\u00a0KT, Diakonis\u00a0VF, Matsou\u00a0A, Tyradellis\u00a0S (2020) Optical coherence tomography angiography in neurodegenerative diseases: a\u00a0review. Eye Brain 12:73\u201387. https:\/\/doi.org\/10.2147\/EB.S193026","journal-title":"Eye Brain"},{"key":"1974_CR38","doi-asserted-by":"publisher","first-page":"e0282175","DOI":"10.1371\/journal.pone.0282175","volume":"18","author":"P Dusek","year":"2023","unstructured":"Dusek\u00a0P, Kopal\u00a0A, Brichova\u00a0M, Roth\u00a0J, Ulmanova\u00a0O, Klempir\u00a0J et\u00a0al (2023) Is retina affected in Huntington\u2019s disease? Is optical coherence tomography a\u00a0good biomarker? PLoS ONE 18:e282175. https:\/\/doi.org\/10.1371\/journal.pone.0282175","journal-title":"PLoS ONE"},{"key":"1974_CR39","doi-asserted-by":"publisher","first-page":"5933","DOI":"10.1007\/s10072-022-06232-3","volume":"43","author":"E Amini","year":"2022","unstructured":"Amini\u00a0E, Moghaddasi\u00a0M, Habibi\u00a0SAH, Azad\u00a0Z, Miri\u00a0S, Nilforushan\u00a0N et\u00a0al (2022) Huntington\u2019s disease and neurovascular structure of retina. Neurol Sci 43:5933\u20135941. https:\/\/doi.org\/10.1007\/s10072-022-06232-3","journal-title":"Neurol Sci"},{"key":"1974_CR40","unstructured":"Vickers A, Ponce C, Skanchy D, Tripathy K (2022) Ophthalmologic Manifestations of Spinocerebellar Ataxia\u2014EyeWiki. https:\/\/eyewiki.aao.org\/Ophthalmologic_Manifestations_of_Spinocerebellar_Ataxia#cite_note-sun4-4. Zugegriffen: 16. Apr. 2023"},{"key":"1974_CR41","doi-asserted-by":"publisher","first-page":"1376","DOI":"10.1038\/eye.2013.201","volume":"27","author":"G Alvarez","year":"2013","unstructured":"Alvarez\u00a0G, Rey\u00a0A, Sanchez-Dalmau\u00a0FB, Mu\u00f1oz\u00a0E, R\u00edos\u00a0J, Ad\u00e1n\u00a0A (2013) Optical coherence tomography findings in spinocerebellar ataxia\u20113. Eye 27:1376\u20131381. https:\/\/doi.org\/10.1038\/eye.2013.201","journal-title":"Eye"},{"key":"1974_CR42","doi-asserted-by":"publisher","first-page":"758","DOI":"10.1002\/mds.28893","volume":"37","author":"FM Rezende Filho","year":"2022","unstructured":"Rezende Filho\u00a0FM, Jurkute\u00a0N, de Andrade\u00a0JBC, Marianelli\u00a0BF, Ferraz Sallum\u00a0JM, Yu-Wai-Man\u00a0P et\u00a0al (2022) Characterization of retinal architecture in spinocerebellar ataxia type\u00a03 and correlation with disease severity. Mov Disord 37:758\u2013766. https:\/\/doi.org\/10.1002\/mds.28893","journal-title":"Mov Disord"},{"key":"1974_CR43","first-page":"2520","volume":"40","author":"V Parisi","year":"1999","unstructured":"Parisi\u00a0V, Manni\u00a0G, Spadaro\u00a0M, Colacino\u00a0G, Restuccia\u00a0R, Marchi\u00a0S et\u00a0al (1999) Correlation between morphological and functional retinal impairment in multiple sclerosis patients. Invest Ophthalmol Vis Sci 40:2520\u20132527","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1974_CR44","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1016\/S1474-4422(17)30278-8","volume":"16","author":"A Petzold","year":"2017","unstructured":"Petzold\u00a0A, Balcer\u00a0LJ, Calabresi\u00a0PA, Costello\u00a0F, Frohman\u00a0TC, Frohman\u00a0EM et\u00a0al (2017) Retinal layer segmentation in multiple sclerosis: a\u00a0systematic review and meta-analysis. Lancet Neurol 16:797\u2013812. https:\/\/doi.org\/10.1016\/S1474-4422(17)30278-8","journal-title":"Lancet Neurol"},{"key":"1974_CR45","doi-asserted-by":"publisher","first-page":"8503859","DOI":"10.1155\/2016\/8503859","volume":"2016","author":"M Satue","year":"2016","unstructured":"Satue\u00a0M, Obis\u00a0J, Rodrigo\u00a0MJ, Otin\u00a0S, Fuertes\u00a0MI, Vilades\u00a0E et\u00a0al (2016) Optical coherence tomography as a\u00a0biomarker for diagnosis, progression, and prognosis of neurodegenerative diseases. J\u00a0Ophthalmol 2016:8503859. https:\/\/doi.org\/10.1155\/2016\/8503859","journal-title":"J Ophthalmol"},{"key":"1974_CR46","doi-asserted-by":"publisher","first-page":"e1100","DOI":"10.1212\/WNL.0000000000200883","volume":"99","author":"RC Kenney","year":"2022","unstructured":"Kenney\u00a0RC, Liu\u00a0M, Hasanaj\u00a0L, Joseph\u00a0B, Abu Al-Hassan\u00a0A, Balk\u00a0LJ et\u00a0al (2022) The role of optical coherence tomography criteria and machine learning in multiple sclerosis and optic neuritis diagnosis. Neurology 99:e1100\u2013e1112. https:\/\/doi.org\/10.1212\/WNL.0000000000200883","journal-title":"Neurology"},{"key":"1974_CR47","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1007\/s10439-022-02930-3","volume":"50","author":"A Montol\u00edo","year":"2022","unstructured":"Montol\u00edo\u00a0A, Cego\u00f1ino\u00a0J, Garcia-Martin\u00a0E, del P\u00e9rez Palomar\u00a0A (2022) Comparison of machine learning methods using spectralis OCT for diagnosis and disability progression prognosis in multiple sclerosis. Ann Biomed Eng 50:507\u2013528. https:\/\/doi.org\/10.1007\/s10439-022-02930-3","journal-title":"Ann Biomed Eng"},{"key":"1974_CR48","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1212\/WNL.0000000000200862","volume":"99","author":"AT Toosy","year":"2022","unstructured":"Toosy\u00a0AT, Eshaghi\u00a0A (2022) Machine learning utility for optical coherence tomography in multiple sclerosis: is the future now? Neurology 99:453\u2013454. https:\/\/doi.org\/10.1212\/WNL.0000000000200862","journal-title":"Neurology"},{"key":"1974_CR49","doi-asserted-by":"publisher","first-page":"1242","DOI":"10.1055\/a-0715-7961","volume":"235","author":"A Papadopoulou","year":"2018","unstructured":"Papadopoulou\u00a0A, Oertel\u00a0FC, Zimmermann\u00a0H, Zeitz\u00a0O, Brandt\u00a0AU, Paul\u00a0F (2018) Optical coherence tomography in disorders of the central nervous system. Klin Monbl Augenheilkd 235:1242\u20131258. https:\/\/doi.org\/10.1055\/a-0715-7961","journal-title":"Klin Monbl Augenheilkd"},{"key":"1974_CR50","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.msard.2018.03.007","volume":"22","author":"R Alonso","year":"2018","unstructured":"Alonso\u00a0R, Gonzalez-Moron\u00a0D, Garcea\u00a0O (2018) Optical coherence tomography as a\u00a0biomarker of neurodegeneration in multiple sclerosis: a\u00a0review. Mult Scler Relat Disord 22:77\u201382. https:\/\/doi.org\/10.1016\/j.msard.2018.03.007","journal-title":"Mult Scler Relat Disord"},{"key":"1974_CR51","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1177\/1352458517694090","volume":"24","author":"D Coric","year":"2018","unstructured":"Coric\u00a0D, Balk\u00a0LJ, Verrijp\u00a0M, Eijlers\u00a0A, Schoonheim\u00a0MM, Killestein\u00a0J et\u00a0al (2018) Cognitive impairment in patients with multiple sclerosis is associated with atrophy of the inner retinal layers. Mult Scler 24:158\u2013166. https:\/\/doi.org\/10.1177\/1352458517694090","journal-title":"Mult Scler"},{"key":"1974_CR52","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1038\/s41433-022-02056-9","volume":"37","author":"S Vujosevic","year":"2023","unstructured":"Vujosevic\u00a0S, Parra\u00a0MM, Hartnett\u00a0ME, O\u2019Toole\u00a0L, Nuzzi\u00a0A, Limoli\u00a0C et\u00a0al (2023) Optical coherence tomography as retinal imaging biomarker of neuroinflammation\/neurodegeneration in systemic disorders in adults and children. Eye 37:203\u2013219. https:\/\/doi.org\/10.1038\/s41433-022-02056-9","journal-title":"Eye"},{"key":"1974_CR53","doi-asserted-by":"publisher","first-page":"1786","DOI":"10.1093\/brain\/aws098","volume":"135","author":"JM Gelfand","year":"2012","unstructured":"Gelfand\u00a0JM, Nolan\u00a0R, Schwartz\u00a0DM, Graves\u00a0J, Green\u00a0AJ (2012) Microcystic macular oedema in multiple sclerosis is associated with disease severity. Brain 135:1786\u20131793. https:\/\/doi.org\/10.1093\/brain\/aws098","journal-title":"Brain"},{"key":"1974_CR54","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/j.ophtha.2013.08.045","volume":"121","author":"M Abegg","year":"2014","unstructured":"Abegg\u00a0M, Dysli\u00a0M, Wolf\u00a0S, Kowal\u00a0J, Dufour\u00a0P, Zinkernagel\u00a0M (2014) Microcystic macular edema: retrograde maculopathy caused by optic neuropathy. Ophthalmology 121:142\u2013149. https:\/\/doi.org\/10.1016\/j.ophtha.2013.08.045","journal-title":"Ophthalmology"},{"key":"1974_CR55","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1097\/IJG.0000000000000633","volume":"26","author":"J Brazerol","year":"2017","unstructured":"Brazerol\u00a0J, Iliev\u00a0ME, H\u00f6hn\u00a0R, Fr\u00e4nkl\u00a0S, Grabe\u00a0H, Abegg\u00a0M (2017) Retrograde maculopathy in patients with glaucoma. J\u00a0Glaucoma 26:423\u2013429. https:\/\/doi.org\/10.1097\/IJG.0000000000000633","journal-title":"J Glaucoma"},{"key":"1974_CR56","doi-asserted-by":"publisher","first-page":"952","DOI":"10.1167\/iovs.13-12912","volume":"55","author":"MC Burggraaff","year":"2014","unstructured":"Burggraaff\u00a0MC, Trieu\u00a0J, de Vries-Knoppert\u00a0WAEJ, Balk\u00a0L, Petzold\u00a0A (2014) The clinical spectrum of microcystic macular edema. Invest Ophthalmol Vis Sci 55:952\u2013961. https:\/\/doi.org\/10.1167\/iovs.13-12912","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1974_CR57","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2014.01.035","author":"OA Mahroo","year":"2014","unstructured":"Mahroo\u00a0OA, Shalchi\u00a0Z, Kisimbi\u00a0J, Sanyiwa\u00a0AJ, Mohamed\u00a0MD, Plant\u00a0GT (2014) Re: Abegg et\u00a0al.: Microcystic macular edema: retrograde maculopathy caused by optic neuropathy (Ophthalmology 2014;121:142\u20139). Ophthalmology. https:\/\/doi.org\/10.1016\/j.ophtha.2014.01.035","journal-title":"Ophthalmology"},{"key":"1974_CR58","doi-asserted-by":"publisher","first-page":"1591","DOI":"10.1093\/brain\/awq080","volume":"133","author":"AJ Green","year":"2010","unstructured":"Green\u00a0AJ, McQuaid\u00a0S, Hauser\u00a0SL, Allen\u00a0IV, Lyness\u00a0R (2010) Ocular pathology in multiple sclerosis: retinal atrophy and inflammation irrespective of disease duration. Brain 133:1591\u20131601. https:\/\/doi.org\/10.1093\/brain\/awq080","journal-title":"Brain"},{"key":"1974_CR59","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1002\/ana.25782","volume":"88","author":"A Petzold","year":"2020","unstructured":"Petzold\u00a0A, Coric\u00a0D, Balk\u00a0LJ, Hamann\u00a0S, Uitdehaag\u00a0BMJ, Denniston\u00a0AK et\u00a0al (2020) Longitudinal development of peripapillary hyper-reflective ovoid masslike structures suggests a\u00a0novel pathological pathway in multiple sclerosis. Ann Neurol 88:309\u2013319. https:\/\/doi.org\/10.1002\/ana.25782","journal-title":"Ann Neurol"},{"key":"1974_CR60","doi-asserted-by":"publisher","DOI":"10.1111\/ene.15056","author":"R Wicklein","year":"2021","unstructured":"Wicklein\u00a0R, Wauschkuhn\u00a0J, Giglhuber\u00a0K, K\u00fcmpfel\u00a0T, Hemmer\u00a0B, Havla\u00a0J et\u00a0al (2021) Association of peripapillary hyper-reflective ovoid masslike structures and disease duration in primary progressive multiple sclerosis. Eur J Neurol. https:\/\/doi.org\/10.1111\/ene.15056","journal-title":"Eur J Neurol"},{"key":"1974_CR61","doi-asserted-by":"publisher","first-page":"1467","DOI":"10.3390\/jcm8091467","volume":"8","author":"S Tomatsu","year":"2019","unstructured":"Tomatsu\u00a0S, Pitz\u00a0S, Hampel\u00a0U (2019) Ophthalmological findings in mucopolysaccharidoses. J\u00a0Clin Med 8:1467. https:\/\/doi.org\/10.3390\/jcm8091467","journal-title":"J Clin Med"},{"key":"1974_CR62","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-021-05424-5","author":"S Hopf","year":"2021","unstructured":"Hopf\u00a0S, Schuster\u00a0AK, Hennermann\u00a0JB, Pfeiffer\u00a0N, Pitz\u00a0S (2021) Retinal thinning in phenylketonuria and Gaucher disease type\u00a03. Graefes Arch Clin Exp Ophthalmol. https:\/\/doi.org\/10.1007\/s00417-021-05424-5","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"1974_CR63","doi-asserted-by":"publisher","first-page":"2211","DOI":"10.1002\/mds.28256","volume":"35","author":"AAG Tantawy","year":"2020","unstructured":"Tantawy\u00a0AAG, Adly\u00a0AAM, Hashem\u00a0NH, Ebeid\u00a0WM, Abdeen\u00a0MS, Salah\u00a0NY (2020) Ganglion cell complex thinning in young gaucher patients: relation to prodromal parkinsonian markers. Mov Disord 35:2211\u20132219. https:\/\/doi.org\/10.1002\/mds.28256","journal-title":"Mov Disord"},{"key":"1974_CR64","doi-asserted-by":"publisher","first-page":"3023","DOI":"10.1007\/s10792-020-01486-2","volume":"40","author":"AI Cakmak","year":"2020","unstructured":"Cakmak\u00a0AI, Atalay\u00a0E, Cankurtaran\u00a0V, Ya\u015far\u00a0E, Turgut\u00a0FH (2020) Optical coherence tomography angiography analysis of fabry disease. Int Ophthalmol 40:3023\u20133032. https:\/\/doi.org\/10.1007\/s10792-020-01486-2","journal-title":"Int Ophthalmol"},{"key":"1974_CR65","unstructured":"Sodi A, Ioannidis A, Pitz S (2006) Ophthalmological manifestations of Fabry disease. In: Mehta A, Beck M, Sunder-Plassmann G, editors. Fabry Disease: Perspectives from 5 Years of FOS. Oxford: Oxford PharmaGenesis. http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK11599\/"},{"key":"1974_CR66","doi-asserted-by":"publisher","first-page":"2070","DOI":"10.1007\/s00415-020-09796-2","volume":"267","author":"J Havla","year":"2020","unstructured":"Havla\u00a0J, Moser\u00a0M, Sztatecsny\u00a0C, Lotz-Havla\u00a0AS, Maier\u00a0EM, Hizli\u00a0B et\u00a0al (2020) Retinal axonal degeneration in niemann-pick type\u00a0C disease. J\u00a0Neurol 267:2070\u20132082. https:\/\/doi.org\/10.1007\/s00415-020-09796-2","journal-title":"J Neurol"},{"key":"1974_CR67","doi-asserted-by":"publisher","first-page":"e0252825","DOI":"10.1371\/journal.pone.0252825","volume":"16","author":"S Hopf","year":"2021","unstructured":"Hopf\u00a0S, Hennermann\u00a0JB, Schuster\u00a0AK, Pfeiffer\u00a0N, Pitz\u00a0S (2021) Vertical saccadic palsy and foveal retinal thinning in niemann-pick disease type\u00a0C. PLoS ONE 16:e252825. https:\/\/doi.org\/10.1371\/journal.pone.0252825","journal-title":"PLoS ONE"},{"key":"1974_CR68","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1097\/ICB.0000000000000200","volume":"10","author":"MS Hansen","year":"2016","unstructured":"Hansen\u00a0MS, Hove\u00a0MN, Jensen\u00a0H, Larsen\u00a0M (2016) Optical coherence tomography In juvenile neuronal ceroid lipofuscinosis. Retin Cases Brief Rep 10:137\u2013139. https:\/\/doi.org\/10.1097\/ICB.0000000000000200","journal-title":"Retin Cases Brief Rep"},{"key":"1974_CR69","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/j.ajo.2022.07.019","volume":"244","author":"A Fie\u00df","year":"2022","unstructured":"Fie\u00df\u00a0A, Sch\u00e4ffler\u00a0A, Mildenberger\u00a0E, Urschitz\u00a0MS, Wagner\u00a0FM, Hoffmann\u00a0EM et\u00a0al (2022) Peripapillary retinal nerve fiber layer thickness in adults born extremely, very, and moderately preterm with and without retinopathy of prematurity: results from the Gutenberg Prematurity Eye Study (GPES). Am J Ophthalmol 244:88\u201397. https:\/\/doi.org\/10.1016\/j.ajo.2022.07.019","journal-title":"Am J Ophthalmol"},{"key":"1974_CR70","doi-asserted-by":"publisher","first-page":"1526","DOI":"10.1016\/j.ophtha.2018.03.026","volume":"125","author":"MM Mauschitz","year":"2018","unstructured":"Mauschitz\u00a0MM, Bonnemaijer\u00a0PWM, Diers\u00a0K, Rauscher\u00a0FG, Elze\u00a0T, Engel\u00a0C et\u00a0al (2018) Systemic and ocular determinants of peripapillary retinal nerve fiber layer thickness measurements in the European Eye Epidemiology (E3) population. Ophthalmology 125:1526\u20131536. https:\/\/doi.org\/10.1016\/j.ophtha.2018.03.026","journal-title":"Ophthalmology"},{"key":"1974_CR71","doi-asserted-by":"publisher","first-page":"e0197682","DOI":"10.1371\/journal.pone.0197682","volume":"13","author":"J Lamparter","year":"2018","unstructured":"Lamparter\u00a0J, Schmidtmann\u00a0I, Schuster\u00a0AK, Siouli\u00a0A, Wasielica-Poslednik\u00a0J, Mirshahi\u00a0A et\u00a0al (2018) Association of ocular, cardiovascular, morphometric and lifestyle parameters with retinal nerve fibre layer thickness. PLoS ONE 13:e197682. https:\/\/doi.org\/10.1371\/journal.pone.0197682","journal-title":"PLoS ONE"},{"key":"1974_CR72","doi-asserted-by":"publisher","first-page":"11161","DOI":"10.1038\/s41598-018-29557-6","volume":"8","author":"JY Moon","year":"2018","unstructured":"Moon\u00a0JY, Kim\u00a0HJ, Park\u00a0YH, Park\u00a0TK, Park\u00a0E\u2011C, Kim\u00a0CY et\u00a0al (2018) Association between Open-Angle Glaucoma and the Risks of Alzheimer\u2019s and Parkinson\u2019s Diseases in South Korea: A\u00a010-year Nationwide Cohort Study. Sci Rep 8:11161. https:\/\/doi.org\/10.1038\/s41598-018-29557-6","journal-title":"Sci Rep"}],"container-title":["Die Ophthalmologie"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00347-023-01974-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00347-023-01974-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00347-023-01974-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,11]],"date-time":"2024-02-11T15:07:24Z","timestamp":1707664044000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00347-023-01974-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,23]]},"references-count":72,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["1974"],"URL":"https:\/\/doi.org\/10.1007\/s00347-023-01974-7","relation":{},"ISSN":["2731-720X","2731-7218"],"issn-type":[{"value":"2731-720X","type":"print"},{"value":"2731-7218","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,23]]},"assertion":[{"value":"18 December 2023","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 January 2024","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"S.\u00a0Hopf, O.\u00a0T\u00fcscher und A.K.\u00a0Schuster geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autor\/-innen keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}