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Alle wiesen ein hohes Risiko f\u00fcr eine Transplantatabsto\u00dfung im Falle einer EK auf (vorherige andere Glaukomoperationen zus\u00e4tzlich zu GDD [<jats:italic>n<\/jats:italic>\u202f=\u20098], Zustand nach Descemet Membran-Endothel-Keratoplastik [DMEK;<jats:italic>n<\/jats:italic>\u202f=\u20099], Uveitis [<jats:italic>n<\/jats:italic>\u202f=\u20092], anteriore Synechien [<jats:italic>n<\/jats:italic>\u202f=\u20092]). Die EndoArt\u00ae wurde mit einer Gasblase und ein bis drei\u00a0Halten\u00e4hten gesichert. Die pr\u00e4- und postoperativ beste brillenkorrigierte Sehsch\u00e4rfe (BSCVA) und die zentrale Hornhautdicke (CCT) wurden bestimmt. Die Notwendigkeit zus\u00e4tzlicher Gasinjektionen (Rebubbling) wurde analysiert.<\/jats:p><\/jats:sec><jats:sec><jats:title>Ergebnisse<\/jats:title><jats:p>Octafluorpropan (C3F8) 12\u202f% wurde bei neun, Schwefelhexafluorid (SF6) 20\u202f% bei drei\u00a0Patienten als Vorderkammertamponnade zur Verbesserung der Anlage von EndoArt\u00ae verwendet. Bei vier\u00a0Augen war mindestens ein Rebubbling n\u00f6tig. Der pr\u00e4operative BSCVA betrug 1,6 (\u00b1\u202f0,5) logMAR und verbesserte sich nach 12\u00a0Wochen signifikant auf 1,1 (\u00b1\u202f0,6) logMAR (<jats:italic>p<\/jats:italic>\u202f=\u20090,028). Die pr\u00e4operative CCT betrug 719\u202f\u00b5m\u202f\u00b1\u2009145,7, sank nach sechs\u00a0Wochen signifikant auf 622,4\u202f\u00b5m\u202f\u00b1\u2009174,9 (<jats:italic>p<\/jats:italic>\u202f=\u20090,004) und nach 12\u00a0Wochen auf 591,7\u202f\u00b5m\u202f\u00b1\u2009190,8 (<jats:italic>p<\/jats:italic>\u202f=\u20090,096). Bei einem Auge wurde das Implantat explantiert, wir gehen von einem fibrotischen Umbau der Hornhaut nach vielfachen vorherigen DMEKs aus.<\/jats:p><\/jats:sec><jats:sec><jats:title>Diskussion<\/jats:title><jats:p>EndoArt\u00ae f\u00fchrte bei Patienten mit GDD zu einer signifikanten Verbesserung des BSCVA und Reduktion der CCT. Allerdings zeigte sich eine hohe Rebubbling-Rate. Bei Patienten mit hohem Risiko f\u00fcr Transplantatversagen kann die Verwendung von EndoArt\u00ae vorteilhaft sein.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00347-024-02122-5","type":"journal-article","created":{"date-parts":[[2024,10,2]],"date-time":"2024-10-02T13:01:37Z","timestamp":1727874097000},"page":"803-813","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["EndoArt\u00ae: Ergebnisse bei Patienten mit Glaukom-Drainage-Implantaten","EndoArt\u00ae: results in patients with glaucoma drainage devices"],"prefix":"10.1007","volume":"121","author":[{"given":"Johanna","family":"Wiedemann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mert","family":"Mestanoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Rekate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Gietzelt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claus","family":"Cursiefen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f6rn","family":"Bachmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,10,2]]},"reference":[{"issue":"(4","key":"2122_CR1","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1016\/j.jfo.2017.12.005","volume":"41","author":"V Kocaba","year":"2018","unstructured":"Kocaba\u00a0V, Damour\u00a0O, Auxenfans\u00a0C et\u00a0al (2018) Descemet\u2019s Membrane Endothelial Keratoplasty. 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